Effects of luteinizing hormone on glucose metabolism in cumulus-enclosed bovine oocytes matured in vitro.

abstract：:The formation of junctional complexes between adjacent epithelial principal cells leads to formation of the blood-epididymal barrier; this barrier is complete by 21 days of postnatal age. Cadherins are cell surface proteins that mediate intercellular adhesion and are involved in the formation of adherence, gap, and ti...

journal_title：Endocrinology

authors： Cyr DG,Hermo L,Robaire B

更新日期：1993-03-01 00:00:00

abstract：:We recently reported that aluminum administration to beagles stimulates uncoupled bone formation in the marrow cavity which increases trabecular bone volume and generates new osseous networks within the axial skeleton. To investigate whether this osteogenic process results from direct stimulation of bone cell replicat...

journal_title：Endocrinology

authors： Quarles LD,Wenstrup RJ,Castillo SA,Drezner MK

更新日期：1991-06-01 00:00:00

abstract：:19-Nor progesterone (19-nor P) has previously been shown to have a approximately 3-fold higher affinity for mineralocorticoid receptors than progesterone (P), its C-19 methylated parent steroid; in contrast, 19-nor aldosterone has less than 1% the mineralocorticoid receptor affinity of aldosterone. In the present stud...

journal_title：Endocrinology

authors： Funder JW,Adam WR

更新日期：1981-07-01 00:00:00

abstract：:We have previously reported that neurotensin (NT) is released from the small intestine and elevated in the hepatic-portal circulation in response to the perfusion of the small intestine with a micellar solution of oleic acid. In order to determine the minimum acyl chain length and whether the presence of a carboxylic ...

journal_title：Endocrinology

authors： Ferris CF,Armstrong MJ,George JK,Stevens CA,Carraway RE,Leeman SE

更新日期：1985-03-01 00:00:00

abstract：:Galanin-like peptide (GALP), a 29-amino-acid neuropeptide, is located in the hypothalamic arcuate nucleus (ARC), binds to galanin receptor subtype 2, and induces food intake upon intracerebroventricular (icv) injection in rats. However, neural mechanisms underlying its orexigenic action remain unclear. We aimed to ide...

journal_title：Endocrinology

authors： Kuramochi M,Onaka T,Kohno D,Kato S,Yada T

更新日期：2006-04-01 00:00:00

abstract：:The activity of many endocrine cells is regulated by gamma-aminobutyric acid (GABA). The effects of GABA are mediated by GABAA and/or GABAB receptors. While GABAB receptors in the central nervous system have now been extensively characterized, little is known of the function and pharmacology of GABAB receptors on endo...

journal_title：Endocrinology

authors： De Koning HP,Jenks BG,Roubos EW

更新日期：1993-02-01 00:00:00

abstract：:A heterologous RIA for ovine inhibin was developed which was sufficiently sensitive and specific to describe the peripheral concentrations of immunoreactive inhibin (iINH) during the estrous cycle of the ewe and to examine the effects of cautery of ovarian follicles on concentrations of iINH in ovarian and jugular ven...

journal_title：Endocrinology

authors： Findlay JK,Clarke IJ,Robertson DM

更新日期：1990-01-01 00:00:00

abstract：:Insulin coordinates the complex response to feeding, affecting numerous metabolic and hormonal pathways. Forkhead box protein O1 (FoxO1) is one of several signaling molecules downstream of insulin; FoxO1 drives gluconeogenesis and is suppressed by insulin. To determine the role of FoxO1 in mediating other actions of i...

journal_title：Endocrinology

authors： Ling AV,Gearing ME,Semova I,Shin DJ,Clements R,Lai ZW,Biddinger SB

更新日期：2018-03-01 00:00:00

abstract：:We have previously shown that plasma IGF 1 concentration is positively correlated with the rate of antler growth and have proposed that IGF 1 is stimulatory for antler growth in the red deer stag. Therefore to partly resolve the question of whether the IGF 1 was of circulating or local origin in relation to its effect...

journal_title：Endocrinology

authors： Suttie JM,Fennessy PF,Gluckman PD,Corson ID

更新日期：1988-06-01 00:00:00

abstract：:IGF-I has been shown to play a role in the progression of atherosclerosis in experimental animal models. IGF-binding protein-4 (IGFBP-4) binds to IGF-I and prevents its association with receptors. Overexpression of a protease-resistant form of IGFBP-4 has been shown to inhibit the ability of IGF-I to stimulate normal ...

journal_title：Endocrinology

authors： Nichols TC,Busby WH Jr,Merricks E,Sipos J,Rowland M,Sitko K,Clemmons DR

更新日期：2007-10-01 00:00:00

abstract：:The pigeon crop has long been known as a target tissue for PRL action. This study investigates the molecular events associated with PRL stimulation of the pigeon crop sac. Several experiments were performed comparing isolates from PRL-injected pigeons (200 micrograms/day, im, for 3 days) to saline-treated pigeons. Ele...

journal_title：Endocrinology

authors： Pukac LA,Horseman ND

更新日期：1984-05-01 00:00:00

abstract：:Insulin stimulation of glucose transport involves the translocation of vesicles containing the glucose transporter Glut 4 to the plasma membrane. Since low mol wt GTP-binding proteins (LMW-GTP-binding proteins) have been implicated in the regulation of vesicular trafficking, we have analyzed these proteins in adipocyt...

journal_title：Endocrinology

authors： Cormont M,Tanti JF,Grémeaux T,Van Obberghen E,Le Marchand-Brustel Y

更新日期：1991-12-01 00:00:00

abstract：:Mammary gland is an organ that undergoes cycles of growth, differentiation, and function during pregnancy and lactation. Although it is known that the gland enhances its sensitivity to insulin during lactation, it remains to be investigated whether this increased sensitivity develops during pregnancy and which are the...

journal_title：Endocrinology

authors： Carrascosa JM,Ramos P,Molero JC,Herrera E

更新日期：1998-02-01 00:00:00

abstract：:The Elovl3 gene belongs to the Elovl gene family, which encodes for enzymes involved in the elongation of very long chain fatty acids. The recognized role for the enzyme is to control the elongation of saturated and monounsaturated fatty acids up to 24 carbons in length. Elovl3 was originally identified as a highly ex...

journal_title：Endocrinology

authors： Brolinson A,Fourcade S,Jakobsson A,Pujol A,Jacobsson A

更新日期：2008-06-01 00:00:00

abstract：:Estrogen sulfotransferase (EST) catalyzes the sulfoconjugation and inactivation of the steroid hormone estrogen. It is known previously that EST is expressed abundantly in Leydig cells of the testis. We recently have shown that male mice with targeted EST gene disruption developed age related Leydig cell and seminifer...

journal_title：Endocrinology

authors： Tong MH,Song WC

更新日期：2002-08-01 00:00:00

abstract：:FSH and IGF-I are both important determinants of testicular development and Sertoli cell function. The present studies were performed to determine the actions of FSH and IGF-I on PI3K/AKT protein kinase signaling in immature rat Sertoli cells. Primary cultures of rat Sertoli cells were prepared from 10-d-old rats. Aft...

journal_title：Endocrinology

authors： Khan SA,Ndjountche L,Pratchard L,Spicer LJ,Davis JS

更新日期：2002-06-01 00:00:00

abstract：:We previously reported that interleukin-1alpha (IL-1alpha)-induced activation of protein kinase C (PKC) via phosphatidylcholine-specific phospholipase C (PC-PLC) limits IL-6 synthesis induced by IL-1alpha itself in osteoblast-like MC3T3-E1 cells. In the present study, we further investigated the mechanism behind IL-1a...

journal_title：Endocrinology

authors： Miwa M,Kozawa O,Tokuda H,Uematsu T

更新日期：1999-11-01 00:00:00

abstract：:Glucagon-like peptide 1 (GLP-1) is both a gut-derived hormone and a neurotransmitter synthesized in the brain. Early reports suggested that GLP-1 acts in the periphery to promote insulin secretion and affect glucose homeostasis, whereas central GLP-1 reduces food intake and body weight. However, current research indic...

journal_title：Endocrinology

authors： Williams DL

更新日期：2009-07-01 00:00:00

abstract：:Male Siberian hamsters undergo physiological weight change in changing photoperiod. Weight loss was induced by food restriction in long days to mimic short-day weight loss, or by food restriction superimposed on short-day weight loss, to test the hypothesis that the hypothalamus differentiates between weight change in...

journal_title：Endocrinology

authors： Mercer JG,Moar KM,Logie TJ,Findlay PA,Adam CL,Morgan PJ

更新日期：2001-10-01 00:00:00

abstract：:The SMRT coregulator functions as a dual coactivator and corepressor for estrogen receptor-α (ERα) in a gene-specific manner, and in several studies its elevated expression correlates with poor outcome for breast cancer patients. A specific role of SMRT in breast cancer progression has not been elucidated, but SMRT kn...

journal_title：Endocrinology

authors： Blackmore JK,Karmakar S,Gu G,Chaubal V,Wang L,Li W,Smith CL

更新日期：2014-09-01 00:00:00

abstract：:We have studied whether activation of cell adhesion kinase beta (CAKbeta) is involved in stretch-induced signaling pathway in cultured rat vascular smooth muscle cells. Cyclic stretch (1 Hz) induced a rapid (within 1 min) phosphorylation of CAKbeta, whose effect was time and strength dependent. Both Ca(2+) and Na(+) i...

journal_title：Endocrinology

authors： Iwasaki H,Yoshimoto T,Sugiyama T,Hirata Y

更新日期：2003-06-01 00:00:00

abstract：:ACTH and cAMP stimulate steroidogenesis and the mitochondrial electron transport system for steroid hydroxylation in cultured mouse adrenal cortex tumor cells. During this stimulation, the biosynthesis of adrenodoxin, a non-heme iron protein which is one of the electron transport enzymes, was examined. 14C-labeled adr...

journal_title：Endocrinology

authors： Asano K,Harding BW

更新日期：1976-10-01 00:00:00

abstract：:The median eminence (ME), which is the common termination field for adenohypophysiotropic systems, has been shown to produce nitric oxide (NO), a signaling molecule involved in neuroendocrine secretion. Using an ex vivo technique, 17beta-estradiol exposure to ME fragments, including vascular tissues, stimulated NO rel...

journal_title：Endocrinology

authors： Prevot V,Croix D,Rialas CM,Poulain P,Fricchione GL,Stefano GB,Beauvillain JC

更新日期：1999-02-01 00:00:00

abstract：:We investigated the role of peritubular cell-Sertoli cell interactions in the control of Sertoli cell function by androgens. Decreased FSH-inducible aromatase activity and increased secretion of androgen-binding protein (ABP) were used as parameters of androgen action on Sertoli cells. It is demonstrated that cocultur...

journal_title：Endocrinology

authors： Verhoeven G,Cailleau J

更新日期：1988-10-01 00:00:00

abstract：:A functioning rat thyroid cell line (FRTL-5) responds acutely to the addition of TSH, norepinephrine, and the Ca2+ ionophore A23187 by a depression in iodide (I-) uptake levels. The decrease in I- content measured at the steady state depends on the presence of external Ca2+ and can be accounted for by an effect on sti...

journal_title：Endocrinology

authors： Weiss SJ,Philp NJ,Grollman EF

更新日期：1984-04-01 00:00:00

abstract：:Insulin acts directly as a mitogen on isolated embryonic tissues but has been shown to be inactive at physiological concentrations on several fetal cell types. Since insulin availability is obligatory for optimal fetal growth, we have investigated its mitogenic actions on chondrocytes isolated from the epiphyseal grow...

journal_title：Endocrinology

authors： Hill DJ,de Sousa D

更新日期：1990-05-01 00:00:00

abstract：:A new hydrolase activity has been identified by its capability of cleaving t-boc-Ala-Ala-Pro-Ala-AMC, the released 7-amino-4-methylcoumarin (AMC) being quantified fluorometrically. The activity in the 28,000 X g supernatant fraction of homogenates of weanling mouse uterus was about one fifth that of the adult mouse. T...

journal_title：Endocrinology

authors： Katz J,Finlay TH,Tom C,Levitz M

更新日期：1980-12-01 00:00:00

abstract：:We have previously demonstrated that cultured rat thyroid cells do not exhibit constitutive expression of major histocompatibility (MHC) class II antigens. Using reovirus types 1 and 3, we infected 1B-6 cells (a cloned derivative of the Fisher rat cell line FRTL-5), and found a dose-dependent induction of thyroid cell...

journal_title：Endocrinology

authors： Neufeld DS,Platzer M,Davies TF

更新日期：1989-01-01 00:00:00

abstract：:It is generally accepted that cholesterol affects dynamic membrane properties and the function of membrane bound proteins involved in secretion processes. In the present study we employed GH4C1 cells treated with human lipoprotein-deficient serum (h-LPDS), exogenous cholesterol and high density lipoprotein (HDL3) to i...

journal_title：Endocrinology

authors： Lasa M,Perez-Caballero FJ,Usera F,Chiloeches A,Montes A,Toro MJ

更新日期：1993-04-01 00:00:00

abstract：:Fasting in rodents is characterized by decreases in serum T4 and T3 levels but no compensatory increase in serum TSH level. The types 1 and 2 deiodinases (D1 and D2) are postulated to play key roles in mediating these changes. However, serum T4 and T3 levels in fasted 5'-deiodinase-deficient mice decreased by at least...

journal_title：Endocrinology

authors： Galton VA,Hernandez A,St Germain DL

更新日期：2014-08-01 00:00:00