Nucleolar organiser regions (AgNORs) related to histopathological characteristics and survival in prostatic adenocarcinoma.

abstract：:The LAI reactivity of a colon organ specific neoantigen (OSN) was recovered from the urine of advanced colon cancer patients. In this study three physico-chemical steps were employed; precipitation by 80% ammonium sulfate, ion exchange, and molecular sieve chromatography. Each isolate was tested for activity and speci...

journal_title：Anticancer research

authors： Fink A,Harpaz N,Weisman Z,Shani A,Bentwich Z

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Licofelone, a potent antiinflammatory agent has been reported to interfere with the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) signaling pathways with few side-effects. However, the underlying mechanism of licofelone against human cancer is not understood. MATERIALS AND METHODS:Human and mouse pros...

journal_title：Anticancer research

authors： Narayanan NK,Nargi D,Attur M,Abramson SB,Narayanan BA

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Oral leukoplakia (LPL) is considered a potentially malignant disorder in the oral cavity and the gastric tract. High mobility group A (HMGA) proteins are important in the transformation of normal cells into cancer cells, but there is a lack of knowledge on their importance in oral cancer development. The aim...

journal_title：Anticancer research

authors： Larsson L,Jäwert F,Magnusson B,Hasséus B,Kjeller G

更新日期：2013-10-01 00:00:00

abstract：:The antitumor activity of (2''R)-4'-O-tetrahydropyranyl adriamycin (pirarubicin; THP) was assessed using human gastric cancer cell lines in vitro and in vivo. The cytotoxicity of THP on MKN-28 and MKN-45 was superior to that of adriamycin (ADM) as detected by a growth assay with an MTT colorimetric endpoint. When the ...

journal_title：Anticancer research

authors： Saikawa Y,Kubota T,Kuo TH,Furukawa T,Kase S,Tanino H,Ishibiki K,Kitajima M,Hoffman RM

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Recently, metastasis associated with the colon cancer 1 (MACC1) gene was identified by genome-wide search for differentially expressed genes in human colon cancer tissues and metastases. Previously, the MACC1 expression levels were examined in colorectal carcinomas and it was found that MACC1 expression show...

journal_title：Anticancer research

authors： Shirahata A,Sakata M,Kitamura Y,Sakuraba K,Yokomizo K,Goto T,Mizukami H,Saito M,Ishibashi K,Kigawa G,Nemoto H,Hibi K

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The osteoclast-specific active TRAP 5b isoform is detectable in serum and claimed to be a specific marker of bone resorption. The present study was undertaken to evaluate the usefulness of TRAP 5b as a serum marker of bone resorption in breast cancer patients with bone metastases. MATERIALS AND METHODS:TRAP...

journal_title：Anticancer research

authors： Capeller B,Caffier H,Sütterlin MW,Dietl J

更新日期：2003-03-01 00:00:00

abstract：:In order to define genes which mediate liver tropism of colon cancer metastasis we have compared the transcriptional profile of 5600 full-length genes using the Affymetrix HuGene FL array technology of the non-metastatic colon cancer cell lines KM12C and the two metastatic cell lines, KM12SM and KM12L4A, which are der...

journal_title：Anticancer research

authors： De Lange R,Burtscher H,Jarsch M,Weidle UH

更新日期：2001-07-01 00:00:00

abstract：:A plethora of contradictory research surrounds vitamin D and its influence on health and disease. This may, in part, result from analytical difficulties with regard to measuring vitamin D metabolites in serum. Indeed, variation exists between analytical techniques and assays used for the determination of serum 25-hydr...

journal_title：Anticancer research

authors： Stokes CS,Lammert F,Volmer DA

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:It is essential that cytotoxic T-lymphocytes (CTLs) recognize tumor-associated antigens (TAAs) and exhibit antitumor effects in immunological responses for tumor rejection. However, only a few cases with oral squamous cell carcinoma (OSCC) have been studied for these antitumor mechanisms. We established a ca...

journal_title：Anticancer research

authors： Okamoto JY,Miyazaki A,Kobayashi JI,Miyamoto S,Sasaki T,Kanaseki T,Hirohashi Y,Torigoe T,Hiratsuka H

更新日期：2017-09-01 00:00:00

abstract：:Tissue polypeptide specific antigen (TPS) is a new tumor proliferation serotest marker. The respective radioimmunodetective procedure is based on the application of monoclonal antibodies raised against one the principle epitopes of tissue polypeptide antigen (TPA). TPS is useful tool for the identification of prolifer...

journal_title：Anticancer research

authors： Tarle M,Kovacić K,Kastelan M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is thought to be the most powerful angiogenic factor in many malignancies while and several reports have determined serum VEGF to be a prognostic indicator for various malignancies. However, serum VEGF may not be suitable for the measurement of circulating VEGF level...

journal_title：Anticancer research

authors： Nakayama Y,Sako T,Shibao K,Okazaki K,Rempo N,Onitsuka K,Minagawa N,Akahane K,Nagashima N,Nagata N,Itoh H

更新日期：2002-07-01 00:00:00

abstract：:Eighteen patients with Zollinger-Ellison syndrome were studied with 111In-pentetreotide SPECT in order to localize gastrinoma, the tumour responsible for this pathology. NMR imaging was also carried out. Eight patients were operated. 111In-pentetreotide was reinjected 4 hours before operation and the radioactivity of ...

journal_title：Anticancer research

authors： Scopinaro F,Schillaci O,Delle Fave G,Danieli R,Materia A,Tavolaro R,Angeletti S,Marignani M,Massa R,Gualdi G,Polettini E,Picardi V,Basso N

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:This study aimed to examine the effect of apigenin on proliferation and apoptosis in HER2-overexpressing MDA-MB-453 breast cancer cells. MATERIALS AND METHODS:The antiproliferative effects of apigenin were examined by proliferation and MTT assays. The effect of apigenin on apoptotic molecules was determined...

journal_title：Anticancer research

authors： Seo HS,Ku JM,Choi HS,Woo JK,Jang BH,Shin YC,Ko SG

更新日期：2014-06-01 00:00:00

abstract：:Fine needle aspiration (FNA) cytology, being the mainstay to diagnose thyroid nodules, does not provide definitive results in a subset of patients. The use of molecular markers testing has been described as a useful aid in differentiation of thyroid nodules that present with an indeterminate cytodiagnosis. Molecular t...

journal_title：Anticancer research

authors： Bhatia P,Deniwar A,Friedlander P,Aslam R,Kandil E

更新日期：2015-03-01 00:00:00

abstract：:Most current anticancer drugs have shown excellent therapeutic effects on human oral squamous cell carcinoma (OSCC), but they also produce potent cytotoxicity in normal oral keratinocytes. This review article summarizes our extensive research of tumor specificity and keratinocyte toxicity of nine groups of compounds s...

journal_title：Anticancer research

authors： Sugita Y,Takao K,Uesawa Y,Sakagami H

更新日期：2017-11-01 00:00:00

abstract：:In vivo investigations on oncogene action may provide new findings on the toxicology of potential carcinogens. In this study we investigated the early effects of different cytostatic protocols on early oncogene expression in CBA/Ca mice. Most of the examined protocols showed detectable early changes, especially those ...

journal_title：Anticancer research

authors： Ember I,Raposa T,Varga C,Kiss I

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:S100(+) dendritic cells and CD57(+) lymphocytes are factors reflecting the immune system's ability to suppress the progress of tumor growth. CD57(+) cells include natural killer cells and late stages of T-effector lymphocytes. We evaluated the relationship between the known clinical and histological factors ...

journal_title：Anticancer research

authors： Liska V,Vycital O,Daum O,Novak P,Treska V,Bruha J,Pitule P,Holubec L

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND/AIM:The purpose of this study was to consider appropriate application of liquid and re-biopsy through analysis of current status in practice. PATIENTS AND METHODS:We performed a retrospective analysis of 22 patients with epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer wh...

journal_title：Anticancer research

authors： Komiya K,Nakashima C,Nakamura T,Hirakawa H,Abe T,Ogusu S,Takahashi K,Takeda Y,Egashira Y,Kimura S,Sueoka-Aragane N

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of oxaliplatin (L-OHP) fractionated over two days with bimonthly 5-fluorouracil (5-FU) and leucovorin (LV), as first-line treatment of metastatic colorectal cancer (MCC) patients. PATIENTS AND METHODS:Fifty-four patients with inoperable MCC (median age, 60 years) were entere...

journal_title：Anticancer research

authors： Recchia F,Rea S,Nuzzo A,Lalli A,Di Lullo L,De Filippis S,Saggio G,Biondi E,Massa E,Mantovani G

更新日期：2004-05-01 00:00:00

abstract：AIM:The aim of the present study was to evaluate how treatment with everolimus changes readouts of the pulmonary function test (PFT) in patients with metastatic renal cell carcinoma (mRCC). We also attempted to determine whether changes of PFT or everolimus-associated non-infectious pneumonitis (NIP) might affect the e...

journal_title：Anticancer research

authors： Park K,Kim HJ,Lee JL,Lee KH,Jeong IG,Song C,Hong BS,Hong J,Kim CS,Ahn H

更新日期：2014-10-01 00:00:00

abstract：:We have reported the presence of a CD4+ subpopulation of Natural Killer cells (NK) in humans. These cells also express HIV coreceptors CCR5 or CXCR4 and are infectable by HIV-1. Infection is productive and persistent in vitro and in vivo. Infected people under therapy have evidence of viral DNA in their NK pool. In vi...

journal_title：Anticancer research

authors： Valentin A,Pavlakis GN

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:In this study, the effect of novel taxane SB-T-1216 and paclitaxel on sensitive MDA-MB-435 and resistant NCI/ADR-RES human breast cancer cells was compared. MATERIALS AND METHODS:Cell growth and survival were evaluated after 96-hour incubation with tested concentrations of taxanes. The effect on the formati...

journal_title：Anticancer research

authors： Kovár J,Ehrlichová M,Smejkalová B,Zanardi I,Ojima I,Gut I

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The different clinical evolution of breast cancer with similar pathological characteristics prompted the authors to investigate the prognostic significance of different biological markers. METHODS:Seventy-one primary breast carcinoma specimens obtained by mastectomy or quadrantectomy were examined for the d...

journal_title：Anticancer research

authors： Midulla C,De Iorio P,Nagar C,Pisani T,Cenci M,Valli C,Nofroni I,Vecchione A

更新日期：1999-09-01 00:00:00

abstract：:During the last 50 years median survival for metastatic breast cancer has not varied and remains 2-3.5 years. To assess the clinical benefit of salvage systemic therapy a retrospective analysis of metastatic breast cancer patients all homogeneously treated with a commonly used first-line anthacycline-containing cytoto...

journal_title：Anticancer research

authors： Campora E,Gardin G,Gasco M,Rosso R,Santi L

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Polymorphisms altering DNA repair capacity may lead to synergistic effects with tobacco carcinogen-induced lung cancer risk. Based on this hypothesis, the relationship between APE1 polymorphism, smoking and the risk of lung cancer was explored. MATERIALS AND METHODS:The distribution of the APE1 Asp148Glu po...

journal_title：Anticancer research

authors： Agaçhan B,Küçükhüseyin O,Aksoy P,Turna A,Yaylim I,Görmüs U,Ergen A,Zeybek U,Dalan B,Isbir T

更新日期：2009-06-01 00:00:00

abstract：:Mechanisms of tumor growth are concerned with the possibility that neoplasms are disturbed in their response to growth factors. Interleukin 2 (IL 2) is secreted by activated T-cells and is required for autocrine T-cell growth. Controversy exists as to the functional capacity of T-lymphocytes in patients with B-cell ch...

journal_title：Anticancer research

authors： Jehn U,Gross HJ,Wachholz K,Pauls R

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:The influence of age on the patterns and outcomes of external beam radiotherapy for clinically localized prostate cancer patients was examined. MATERIALS AND METHODS:The Japanese Patterns of Care Study surveys were used to compare the processes and outcomes of radical external beam radiotherapy in 140 elder...

journal_title：Anticancer research

authors： Ogawa K,Nakamura K,Onishi H,Koizumi M,Sasaki T,Araya M,Miyabe Y,Otani Y,Teshima T,Japanese Patterns of Care Study Working Subgroup of Prostate Cancer.

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND/AIM:Malignant tumors of the salivary glands are rare and heterogeneous, with more than 20 subtypes, and classified mainly by histopathology. Their diagnosis is often challenging and their etiology unknown. Here, the possible association between human polyomaviruses (PyVs) and one or more salivary gland tumor...

journal_title：Anticancer research

authors： Ramqvist T,Ursu RG,Haeggblom L,Mirzaie L,Gahm C,Hammarstedt-Nordenvall L,Dalianis T,Näsman A

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:DNA repair is a crucial phenomenon that maintains the chromosome integrity of genome which are continuously damaged by endogenous and exogenous alkylating agents. If the damaged DNA is not repaired, it may lead to mutation, chromosomal aberration, aging and cancer. N-methylpurine-DNA glycosylase (MPG), a ubi...

journal_title：Anticancer research

authors： Kim NK,Lee SH,Sohn TJ,Roy R,Mitra S,Chung HM,Ko JJ,Cha KY

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND/AIMS:Our study aimed to compared 3-year results following laparoscopy-assisted proximal gastrectomy (LAPG)-double tract anastomosis (DTA) and lower esophageal sphincter-preserving LAPG (LES-LAPG). PATIENTS AND METHODS:Nine patients who underwent LES-LAPG and 23 LAPG-DTA were compared regarding 3-year follow...

journal_title：Anticancer research

authors： Kim DJ,Kim W

更新日期：2019-01-01 00:00:00