Maternal serum CA 125 for aneuploidy detection in early pregnancy.

Abstract:

:Maternal serum CA 125 levels were determined at 9-11 menstrual weeks for 26 cases of trisomy 13 (n = 4), trisomy 18 (n = 7), trisomy 21 (n = 15), and appropriate controls. There were no statistically significant differences between groups.

journal_name

Prenat Diagn

journal_title

Prenatal diagnosis

authors

Norton ME,Golbus MS

doi

10.1002/pd.1970120911

subject

Has Abstract

pub_date

1992-09-01 00:00:00

pages

779-81

issue

9

eissn

0197-3851

issn

1097-0223

journal_volume

12

pub_type

杂志文章
  • Transcervical (TC) and transabdominal (TA) CVS for prenatal diagnosis in Rotterdam: experience with 3611 cases.

    abstract::Data from 3611 consecutive CVS (TC, N = 1780; TA, N = 1831) were analysed with emphasis put on influence of maternal and gestational age at CVS on the fetal loss rate less than 28 weeks. For TC-CVS the gestational age varied from 9.3-11.6 weeks, for TA-CVS from 9.3-20 weeks. Sampling efficacy at first attempt was 86.5...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.1970110811

    authors: Jahoda MG,Brandenburg H,Reuss A,Cohen-Overbeek TE,Wladimiroff JW,Los FJ,Sachs ES

    更新日期:1991-08-01 00:00:00

  • Comparison of urinary free beta (hCG) and beta-core (hCG) in prenatal screening for chromosomal abnormalities.

    abstract::To evaluate the potential utility of free beta (hCG) and beta-core (hCG) in a prenatal screening protocol for Down syndrome we analysed these markers in dried maternal urine specimens from 163 control, 13 Down syndrome and 5 trisomy 18 pregnancies from 8 to 25 weeks' gestation. All results are reported after normaliza...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0223(199809)18:9<893::aid-pd362

    authors: Hallahan TW,Krantz DA,Tului L,Alberti E,Buchanan PD,Orlandi F,Klein V,Larsen JW Jr,Macri JN

    更新日期:1998-09-01 00:00:00

  • Fetal brain-sparing after laser surgery for twin-twin transfusion syndrome appears associated with two-year neurodevelopmental outcomes.

    abstract:OBJECTIVE:The cerebroplacental ratio (CPR) is a semi-quantitative marker for fetal brain-sparing. Our purpose was to measure the CPR at the time of treatment with selective laser photocoagulation of communicating vessels in gestations with twin-twin transfusion syndrome (TTTS) to test its association with neurological ...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.4713

    authors: Chmait RH,Chon AH,Schrager SM,Llanes A,Hamilton A,Vanderbilt DL

    更新日期:2016-01-01 00:00:00

  • Non-mosaic trisomy 20 presenting at 21 weeks' gestation as a thoraco-abdominal mass.

    abstract::Non-mosaic trisomy 20 is rare in fetuses surviving beyond the first trimester. We report a case of a fetus with non-mosaic trisomy 20 in amniotic fluid cultures obtained during the prenatal evaluation of an unusual thoraco-abdominal mass which was found at autopsy to be pulmonary sequestration. Gross inspection and au...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.65

    authors: Driggers RW,Bernstein H,Lantz M,Stetten G,Escallon CS,Perlman E,Blakemore KJ

    更新日期:2001-05-01 00:00:00

  • Pregnancy outcome after transcervical CVS with a flexible biopsy forceps: evaluation of risk factors.

    abstract::The pregnancy outcome of 1936 women who had transcervical chorionic villus sampling (CVS) with a flexible biopsy forceps was evaluated. Follow-up until 4 weeks after delivery was 99.4 per cent. Various patient- and procedure-related risk factors for spontaneous loss (fetal or neonatal death) were analysed using stepwi...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.1970150904

    authors: Lunshof S,Boer K,Leschot NJ,Pomp M,Wolf H

    更新日期:1995-09-01 00:00:00

  • hCG and the free beta-subunit as screening tests for Down syndrome.

    abstract::Published studies have reached varying conclusions as to the benefit of replacing human chorionic gonadotropin (hCG) measurements with the free beta-subunit of hCG (the free beta-subunit) for Down syndrome screening. One study reports 14 per cent higher detection for the free beta-subunit, while another finds an actua...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:

    authors: Knight GJ,Palomaki GE,Neveux LM,Fodor KK,Haddow JE

    更新日期:1998-03-01 00:00:00

  • Prenatal ultrasound diagnosis of frontonasal dysplasia.

    abstract::We report a case of prenatal ultrasound diagnosis of frontonasal dysplasia. This represents a very rare disorder involving the face (hypertelorism, median cleft lip, absence of the nasal tip) and often the central nervous system (CNS) (cranium bifidum occultum, ethmoidal cephalocele, agenesis of the corpus callosum). ...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.287

    authors: Martinelli P,Russo R,Agangi A,Paladini D

    更新日期:2002-05-01 00:00:00

  • The use of transferrin for enrichment of fetal cells from maternal blood.

    abstract::Iron loaded transferrin (holotransferrin) was used for enrichment of fetal cells from peripheral blood of pregnant women. Cord blood samples were used to evaluate enrichment efficacy of single and double MACS separations. Blood samples were obtained from 10 pregnant women prior to chorion villus sampling (CVS). Erythr...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:

    authors: Serlachius M,Von Koskull H,Wessman M,Schröder J

    更新日期:2000-05-01 00:00:00

  • Prenatal diagnosis of long QT syndrome using fetal magnetocardiography.

    abstract::We describe the detection of congenital long QT syndrome in a fetus at 37 weeks' gestation using magnetocardiography (MCG). The prenatal diagnosis was confirmed by standard electrocardiography (ECG) performed after birth. This is the first case report of fetal long QT syndrome detected by MCG. Fetal MCG may be useful ...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0223(199907)19:7<677::aid-pd597

    authors: Hamada H,Horigome H,Asaka M,Shigemitsu S,Mitsui T,Kubo T,Kandori A,Tsukada K

    更新日期:1999-07-01 00:00:00

  • Detection of fetomaternal haemorrhage associated with cordocentesis using serum alpha-fetoprotein and the Kleihauer technique.

    abstract::Fetomaternal haemorrhage (FMH) was studied after 46 cordocenteses. alpha-Fetoprotein (AFP) concentration and Kleihauer staining of maternal blood, taken both before and after the procedure, revealed increases in AFP values of more than 40 per cent in 30 per cent of the patients examined; fetal haemorrhage of more than...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.1970150403

    authors: Van Selm M,Kanhai HH,Van Loon AJ

    更新日期:1995-04-01 00:00:00

  • Two-colour immunocytochemical staining of gamma (gamma) and epsilon (epsilon) type haemoglobin in fetal red cells.

    abstract::We have developed a two-colour immunocytochemical staining method for the detection of fetal and embryonic haemoglobin in erythroid cells. The method was applied to study these haemoglobin types in fetal red cells. Specimens from fetal blood (10 weeks), cord blood and fetal liver (14 weeks) as well as chorionic villus...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0223(199811)18:11<1131::aid-pd4

    authors: Mesker WE,Ouwerkerk-van Velzen MC,Oosterwijk JC,Bernini LF,Golbus MS,Kanhai HH,Van Ommen GJ,Tanke HJ

    更新日期:1998-11-01 00:00:00

  • Noninvasive prenatal detection of sex chromosomal aneuploidies by sequencing circulating cell-free DNA from maternal plasma.

    abstract:OBJECTIVE:Whole-genome sequencing of circulating cell free (ccf) DNA from maternal plasma has enabled noninvasive prenatal testing for common autosomal aneuploidies. The purpose of this study was to extend the detection to include common sex chromosome aneuploidies (SCAs): [47,XXX], [45,X], [47,XXY], and [47,XYY] syndr...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.4127

    authors: Mazloom AR,Džakula Ž,Oeth P,Wang H,Jensen T,Tynan J,McCullough R,Saldivar JS,Ehrich M,van den Boom D,Bombard AT,Maeder M,McLennan G,Meschino W,Palomaki GE,Canick JA,Deciu C

    更新日期:2013-06-01 00:00:00

  • Prenatal ultrasound evaluation of fetal Hb Bart's disease among pregnancies at risk at 11 to 14 weeks of gestation.

    abstract:OBJECTIVE:The objective of this article is to evaluate the efficacy of the first trimester sonomarkers (11-14 weeks) in predicting hemoglobin (Hb) Bart's disease among fetuses at risk MATERIALS AND METHODS:Prospective analysis was conducted on pregnancies at risk of fetal Hb Bart's disease at 11 to 14 weeks of gestati...

    journal_title:Prenatal diagnosis

    pub_type: 临床试验,杂志文章

    doi:10.1002/pd.4293

    authors: Sirichotiyakul S,Luewan S,Srisupundit K,Tongprasert F,Tongsong T

    更新日期:2014-03-01 00:00:00

  • Prenatal diagnosis of congenital heart defect by genome-wide high-resolution SNP array.

    abstract:OBJECTIVE:This study aimed to detect genomic imbalances in fetuses with congenital heart defect (CHD) by high-resolution single-nucleotide polymorphism (SNP) array. METHODS:A total of 99 fetuses with CHDs with or without other ultrasound anomalies (including structural anomalies and soft markers) but normal karyotypes...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.4383

    authors: Liao C,Li R,Fu F,Xie G,Zhang Y,Pan M,Li J,Li D

    更新日期:2014-09-01 00:00:00

  • Antenatal sonographic findings of right pulmonary agenesis with ipsilateral microtia: a possible new laterality association.

    abstract::Right pulmonary agenesis is a rare congenital malformation which results in secondary dextrocardia in situs solitus. Ipsilateral microtia in this context composes a laterality syndrome. The prenatal sonographic findings of this abnormality have not been previously reported. We describe the association of dextrocardia ...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/1097-0223(200102)21:2<125::aid-pd999>3.0.c

    authors: Maymon R,Schneider D,Hegesh J,Herman A,Weinraub Z,Achiron R

    更新日期:2001-02-01 00:00:00

  • COFFEE: control-free noninvasive fetal chromosomal examination using maternal plasma DNA.

    abstract:OBJECTIVE:The aim of this study is to develop an approach for analyzing plasma DNA sequencing data for noninvasive fetal chromosomal aneuploidy testing that does not require the comparison with control samples or a series of selected genomic regions. RESULTS:We developed the control-free noninvasive fetal chromosomal ...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.5016

    authors: Sun K,Chan KC,Hudecova I,Chiu RW,Lo YM,Jiang P

    更新日期:2017-04-01 00:00:00

  • Meckel-Gruber syndrome: prenatal diagnosis at 10 menstrual weeks using embryoscopy.

    abstract::A case of Meckel-Gruber syndrome was diagnosed by embryoscopy at 10 menstrual weeks, allowing for early termination of pregnancy. Post-mortem examination confirmed the presence of polydactyly and bilateral cystic lesions of the mesonephros and metanephros. Both the forming nephrons and the collecting ducts were involv...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.1970140210

    authors: Dumez Y,Dommergues M,Gubler MC,Bunduki V,Narcy F,LeMerrer M,Mandelbrot L,Berkowitz R

    更新日期:1994-02-01 00:00:00

  • Prenatal brain imaging in congenital toxoplasmosis.

    abstract:OBJECTIVE:To describe brain imaging findings and outcomes in fetuses with confirmed congenital toxoplasmosis (CTX). METHODS:Physicians from Prenatal Diagnosis Units in ten Latin American countries were contacted and asked to provide data on fetuses with ultrasound findings suggestive of intrauterine infection and a po...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.2795

    authors: Malinger G,Werner H,Rodriguez Leonel JC,Rebolledo M,Duque M,Mizyrycki S,Lerman-Sagie T,Herrera M

    更新日期:2011-09-01 00:00:00

  • Cervical teratoma: prenatal diagnosis and long-term follow-up.

    abstract::Cervical teratomas are rare tumours which are the result of abnormal prenatal development. They are usually detected at birth, but can occasionally remain silent until adulthood. Obstruction of the airway is the major challenge in the neonatal period. Prenatal diagnosis allows for early consultation with paediatric su...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:

    authors: Kerner B,Flaum E,Mathews H,Carlson DE,Pepkowitz SH,Hixon H,Graham JM Jr

    更新日期:1998-01-01 00:00:00

  • Early prenatal diagnosis of ventricular diverticulum complicated by serous pericardial effusion.

    abstract::An unusual case of apical diverticulum complicated by serous pericardial effusion and diagnosed ultrasonographically at 13 weeks of gestation is described. A therapeutic abortion was induced at 14 weeks and the complete post-mortem examination did not show additional malformation. Cardiac diverticulum is a rare malfor...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.1970150817

    authors: Carles D,Maugey-Laulom B,Habboud H,Alberti EM,Weichhold W,Léger F

    更新日期:1995-08-01 00:00:00

  • Direct quantification of fetal cells in maternal blood by real-time PCR.

    abstract:BACKGROUND:Fetal cells in maternal blood still present an enticing alternative for the development of a safe and efficacious non-invasive method for prenatal diagnosis. However, most enrichment methods are very tedious and have failed to realise this long sought after goal. We developed a simple, robust TaqMan real-tim...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.1521

    authors: Zhong XY,Holzgreve W,Hahn S

    更新日期:2006-09-01 00:00:00

  • Fetal myelomeningocele surgery: Only treating the tip of the iceberg.

    abstract:OBJECTIVE:Fetal myelomeningocele (fMMC) surgery improves infant outcomes when compared with postnatal surgery. Surgical selection criteria and the option of pregnancy termination, however, limit the number of cases that are eligible for prenatal surgery. We aimed to quantify what proportion of cases could ultimately be...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.5390

    authors: AlRefai A,Drake J,Kulkarni AV,Connor KL,Shannon P,Toi A,Chitayat D,Blaser S,Church PT,Abbasi N,Ryan G,Van Mieghem T

    更新日期:2019-01-01 00:00:00

  • Anxiety in women with low maternal serum alpha-fetoprotein screening results.

    abstract::The purpose of this study was to measure anxiety in pregnant women who had low maternal serum alpha-fetoprotein (MSAFP) screening test levels, received genetic counselling and chose to undergo amniocentesis for fetal chromosome analysis. Their anxiety levels were compared with the levels in women undergoing amniocente...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.1970110607

    authors: Abuelo DN,Hopmann MR,Barsel-Bowers G,Goldstein A

    更新日期:1991-06-01 00:00:00

  • Can we predict 22q11 status of fetuses with tetralogy of Fallot?

    abstract:OBJECTIVE:To determine if chromosome 22q11 deletion status can be predicted in fetuses with tetralogy of Fallot as regards additional phenotypic anomalies. METHODS:One hundred and fifty-one consecutive fetuses with tetralogy of Fallot without or with pulmonary atresia were screened for 22q11 deletion. Additional echog...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.295

    authors: Boudjemline Y,Fermont L,Le Bidois J,Villain E,Sidi D,Bonnet D

    更新日期:2002-03-01 00:00:00

  • First-trimester screening for Down syndrome with ductus venosus Doppler studies in addition to nuchal translucency and serum markers.

    abstract:OBJECTIVE:To estimate the improvement in screening efficiency when fetal ductus venosus Doppler studies are added to existing first-trimester Down syndrome screening protocols. METHODS:Statistical modelling was used with parameters derived from prospective ductus venosus studies and from the published literature. The ...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.1203

    authors: Borrell A,Gonce A,Martinez JM,Borobio V,Fortuny A,Coll O,Cuckle H

    更新日期:2005-10-01 00:00:00

  • Subtle findings on fetal brain imaging in CMV infected pregnancies: What is the clinical significance? A retrospective analysis with outcome correlation.

    abstract:OBJECTIVE:To describe the prognosis of subtle findings on fetal brain imaging in pregnant women with primary CMV infection during pregnancy. METHODS:This was a retrospective study. The data included: timing of infection, amniocentesis results, imaging findings, obstetric outcome, and developmental assessment. RESULTS...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.5634

    authors: Roee B,Adi W,Michael B,Igal W,Karina KH,Liat BS,Gustavo M

    更新日期:2020-03-01 00:00:00

  • Familial supernumerary marker chromosome evolution through three generations.

    abstract::A mosaic chromosome complement, 46,XY/47,XY,+r(15), was detected at prenatal diagnosis. Family studies showed the mother and one of her two children to have a bisatellited supernumerary marker chromosome (SMC) in all lymphocytes examined. The maternal grandfather also showed a bisatellited SMC, but in only 2 per cent ...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0223(199802)18:2<178::aid-pd233

    authors: Adhvaryu SG,Peters-Brown T,Livingston E,Qumsiyeh MB

    更新日期:1998-02-01 00:00:00

  • Multiplex ligation-dependent probe amplification (MLPA) in prenatal diagnosis-experience of a large series of rapid testing for aneuploidy of chromosomes 13, 18, 21, X, and Y.

    abstract:BACKGROUND:Multiplex ligation-dependent probe amplification (MLPA) is a relatively new method for rapid prenatal diagnosis of common aneuploidies, and larger series to evaluate its performance remain to be reported. METHODS:A total of 2400 prenatal chorionic villus samples (CVS) and 1525 prenatal samples of amniotic f...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.2137

    authors: Gerdes T,Kirchhoff M,Lind AM,Vestergaard Larsen G,Kjaergaard S

    更新日期:2008-12-01 00:00:00

  • Molecular characterisation of a prenatally diagnosed 5q15q21.3 deletion and review of the literature.

    abstract:BACKGROUND:Ultrasound examination performed on a 32-year old woman at 30 weeks' gestation showed the presence of fetal malformations. Amniocentesis was performed. METHODS AND RESULTS:Cytogenetic analysis of cultured amniocytes revealed an interstitial deletion of the long arm of chromosome 5. Molecular studies confirm...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章,评审

    doi:10.1002/pd.1386

    authors: Malan V,Martinovic J,Sanlaville D,Caillat S,Waill MC,Ganne ML,Tantau J,Attie-Bitach T,Vekemans M,Morichon-Delvallez N

    更新日期:2006-03-01 00:00:00

  • Fetal brain injury in complicated monochorionic pregnancies: diagnostic yield of prenatal MRI following surveillance ultrasound and influence on prognostic counselling.

    abstract:OBJECTIVE:This study aimed to determine the additional diagnostic information provided by prenatal (fetal) magnetic resonance imaging (pMRI) following tertiary ultrasound (US) for fetal cranial abnormalities in complicated monochorionic gestations. METHODS:Women with complicated monochorionic gestations complicated by...

    journal_title:Prenatal diagnosis

    pub_type: 杂志文章

    doi:10.1002/pd.5059

    authors: Robinson A,Teoh M,Edwards A,Fahey M,Goergen S

    更新日期:2017-06-01 00:00:00