A randomized, double-blind, placebo-controlled study to evaluate topical anaesthesia of the pharynx in upper gastrointestinal endoscopy.

Abstract:

:Reduction of discomfort during diagnostic upper endoscopy may not be desired by patients if the medication has long-lasting and severe after-effects. The present study was designed to examine whether topical anaesthesia of the pharynx without concomitant sedation is of overall benefit to patients undergoing diagnostic upper endoscopy. Two hundred out-patients were randomized to receive in the form of a pharyngeal spray either 80-120 mg lidocaine or placebo. Patients assessed discomfort on a 100 mm visual analogue scale the day after examination. Patients undergoing endoscopy who received lidocaine spray experienced significantly less discomfort from the intubation (p = 0.0001), and discomfort induced by the rest of the examination was also reduced (p = 0.003). The outcome of the endoscopists' assessment was also in favour of lidocaine spray for intubation (p = 0.157) and ease of examination (p = 0.0014). The assessment of throat discomfort suffered by patients after endoscopy did not differ between the groups. A majority of patients, the same proportion in each group, stated they would prefer their next endoscopy to be performed with topical anaesthesia.

journal_name

Endoscopy

journal_title

Endoscopy

authors

Hedenbro JL,Ekelund M,Jansson O,Lindblom A

doi

10.1055/s-2007-1010550

subject

Has Abstract

pub_date

1992-08-01 00:00:00

pages

585-7

issue

6

eissn

0013-726X

issn

1438-8812

journal_volume

24

pub_type

临床试验,杂志文章,随机对照试验
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    abstract::The management of colonoscopic perforations is still evolving. Many now agree to the selective management strategy: Perforations during diagnostic colonoscopy being treated surgically and therapeutic ones treated conservatively. However, patients with diagnostic perforation, if they have clean bowel and no signs of pe...

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    pub_type: 杂志文章

    doi:10.1055/s-2007-1001423

    authors: Soliman A,Grundman M

    更新日期:1998-11-01 00:00:00

  • Endoscopic treatment of scar stenosis in the upper GI tract.

    abstract::Short cicatricial stenoses following surgery of the upper gastrointestinal tract are difficult to treat and have a high recurrence rate. A method of eliminating stenoses endoscopically with the aid of diathermy is described. This method has, to date, been employed in 51 patients, and only a single serious complication...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1018571

    authors: Groitl H

    更新日期:1984-09-01 00:00:00

  • Efficacy and safety of endoscopic biliary lithotripsy using FREDDY laser with a radiopaque mark under fluoroscopic guidance.

    abstract::To date no clinic trials have reported on the safety and effectiveness of the use of a frequency-doubled double pulse neodymium YAG (FREDDY) laser with a radiopaque mark under fluoroscopic guidance to treat bile duct stones that are untreatable by conventional endoscopic therapy. We report the cases of 30 patients wit...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0030-1256555

    authors: Liu F,Jin ZD,Zou DW,Li ZS

    更新日期:2011-10-01 00:00:00

  • A blinded, randomized comparison of a novel, low-dose, triple regimen with fleet phospho-soda: a study of colon cleanliness, speed and success of colonoscopy.

    abstract:BACKGROUND AND STUDY AIMS:A clean colon is essential for an efficient examination. The aim of this study was to compare a novel low-dose, low volume triple regimen with Fleet Phospho-soda. METHODS:A blinded, experienced colonoscopist examined 132 consecutive patients randomly allocated to receive either a triple regim...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2000-133

    authors: Chilton AP,O'Sullivan M,Cox MA,Loft DE,Nwokolo CU

    更新日期:2000-01-01 00:00:00

  • Exploring the clinical potential of an automatic colonic polyp detection method based on the creation of energy maps.

    abstract:BACKGROUND AND AIMS:Polyp miss-rate is a drawback of colonoscopy that increases significantly for small polyps. We explored the efficacy of an automatic computer-vision method for polyp detection. METHODS:Our method relies on a model that defines polyp boundaries as valleys of image intensity. Valley information is in...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0042-108434

    authors: Fernández-Esparrach G,Bernal J,López-Cerón M,Córdova H,Sánchez-Montes C,Rodríguez de Miguel C,Sánchez FJ

    更新日期:2016-09-01 00:00:00

  • Ulcerative colitis in a patient with Wiskott-Aldrich syndrome.

    abstract::A 30-year-old man with underlying Wiskott-Aldrich syndrome, which is a rare X-linked congenital immunodeficiency syndrome characterized by recurrent infections, thrombopenia, eczema and hematopoietic malignancies, presented with bloody diarrhea. Endoscopic and histological evaluation was compatible with ulcerative col...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2002-34272

    authors: Folwaczny C,Ruelfs C,Walther J,König A,Emmerich B

    更新日期:2002-10-01 00:00:00

  • Added value of narrow band imaging and confocal laser endomicroscopy in detecting Barrett's esophagus neoplasia.

    abstract:BACKGROUND AND STUDY AIMS:Advances in endoscopic imaging techniques have enabled more accurate identification of subtle mucosal abnormalities. The aim of the study was to assess the accuracy of predicting high grade dysplasia (HGD) and intramucosal cancer (IMC) in mucosa predicted as being nondysplastic vs. dysplastic ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0032-1325734

    authors: Jayasekera C,Taylor AC,Desmond PV,Macrae F,Williams R

    更新日期:2012-12-01 00:00:00

  • Patients' willingness to defer resection of diminutive polyps: results of a multicenter survey.

    abstract::BACKGROUND AND STUDY AIMS : Current colonoscopy practice requires removal of diminutive polyps. This is associated with costs, but the benefits to colorectal cancer (CRC) prevention remain unclear. The study aim was to understand patients' willingness to defer resection of diminutive polyps and to examine the factors ...

    journal_title:Endoscopy

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0043-121221

    authors: von Renteln D,Bouin M,Barkun AN,Weber A,Robertson DJ,Anderson JC,Pohl H

    更新日期:2018-03-01 00:00:00

  • Laser-induced shockwave lithotripsy of gallstones.

    abstract::With the aid of a Q-switched Nd:YAG laser with energy transmission via a flexible glass fiber, it proves possible under laboratory conditions, to destroy gallstones reliably and reproducibly. Lithotripsy is effected mechanically via a laser-induced local shockwave. ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1018340

    authors: Ell C,Wondrazek F,Frank F,Hochberger J,Lux G,Demling L

    更新日期:1986-05-01 00:00:00

  • Endoscopic submucosal dissection in a European setting. A multi-institutional report of a technique in development.

    abstract:BACKGROUND AND STUDY AIMS:Endoscopic submucosal dissection (ESD) is a technique for "en bloc" resection of superficial tumors of the gastrointestinal tract. In France, experience with this technique is still limited. We wanted to assess the development of ESD in France, with special attention to short term outcomes. P...

    journal_title:Endoscopy

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0030-1256413

    authors: Farhat S,Chaussade S,Ponchon T,Coumaros D,Charachon A,Barrioz T,Koch S,Houcke P,Cellier C,Heresbach D,Lepilliez V,Napoleon B,Bauret P,Coron E,Le Rhun M,Bichard P,Vaillant E,Calazel A,Bensoussan E,Bellon S,Mangiala

    更新日期:2011-08-01 00:00:00

  • Development and use of a quality scale for assessing studies that analyze the diagnostic capacity of capsule endoscopy.

    abstract:BACKGROUND AND STUDY AIMS:The aim of this study was to develop a scale for assessing the quality of published studies on capsule endoscopy, and to apply it to research papers retrieved by a systematic review. METHODS:The scale was based on the evidence-based quality assessment tools used in diagnostic accuracy studies...

    journal_title:Endoscopy

    pub_type: 杂志文章,meta分析

    doi:10.1055/s-2006-944958

    authors: Varela-Lema L,Ruano-Ravina A

    更新日期:2006-12-01 00:00:00

  • Prevalence of buried Barrett's metaplasia in patients before and after radiofrequency ablation.

    abstract:BACKGROUND AND STUDY AIM:Radiofrequency ablation (RFA) to treat Barrett's esophagus is increasingly accepted. Description of the etiology, natural history, and prevalence of buried Barrett's metaplasia (BBM) following RFA is limited, although BBM continues to pose a clinical dilemma. We aimed to assess the prevalence, ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0032-1325678

    authors: Yuan J,Hernandez JC,Ratuapli SK,Ruff KC,De Petris G,Lam-Himlin DM,Burdick GE,Pannala R,Ramirez FC,Fleischer DE

    更新日期:2012-11-01 00:00:00

  • Overcoming the barriers to dissemination and implementation of quality measures for gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) and United European Gastroenterology (UEG) position statement.

    abstract::The European Society of Gastrointestinal Endoscopy (ESGE) has developed performance measures and established a framework for quality assessment for gastrointestinal endoscopy in Europe. Most national societies actively undertake initiatives to implement and explicitly endorse these quality indicators. Given this, ESGE...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/a-1312-6389

    authors: Bisschops R,Rutter MD,Areia M,Spada C,Domagk D,Kaminski MF,Veitch A,Khannoussi W,Gralnek IM,Hassan C,Messmann H,Ponchon T,Fockens P,Dignass A,Dinis-Ribeiro M

    更新日期:2021-02-01 00:00:00

  • Endoscopic treatment of precanceroses and early gastric carcinoma.

    abstract::A plea is made for individual age-adjusted endoscopic therapy of precancerous lesions and, under certain conditions, of early gastric carcinoma. True adenoma and borderline lesion have to be resected, if technically feasible, by snare ectomy. Tumour remnants or local recurrences can be destroyed by argon laser applica...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1021723

    authors: Rösch W,Frühmorgen P

    更新日期:1980-05-01 00:00:00

  • Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of sarcoidosis.

    abstract:BACKGROUND AND STUDY AIMS:Transesophageal endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of mediastinal lymph nodes is increasingly used to detect noncaseating granulomas in patients with suspected sarcoidosis. The optimal needle size and tissue processing method for detecting noncaseating granulomas are...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0029-1243890

    authors: von Bartheld MB,Veseliç-Charvat M,Rabe KF,Annema JT

    更新日期:2010-03-01 00:00:00

  • Utility of laser-cut covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a single-center experience.

    abstract:BACKGROUND:Few reports have evaluated the effectiveness of laser-cut, covered, self-expandable metal stents (LC-CSEMS) for unresectable malignant distal biliary obstruction (MDBO) and whether reintervention is feasible after placement. We describe our experience with LC-CSEMS placement for unresectable MDBO. METHODS:P...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/a-1149-1700

    authors: Marui S,Uza N,Yamazaki H,Ota S,Nakamura T,Yoshida H,Okada H,Hirano T,Kuwada T,Sogabe Y,Tomono T,Matsumori T,Morita T,Nishikawa Y,Tsuda M,Maruno T,Shiokawa M,Kodama Y,Seno H

    更新日期:2020-08-01 00:00:00

  • Gallstone ileus revealed by endoscopy.

    abstract::Report on a female patient withe intestinal obstruction which endoscopically showed two radiolucent gallstones visualized by radiological examination of the duodenum with barium and removed through a gastrotomy. ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0028-1098500

    authors: Tauris P

    更新日期:1977-05-01 00:00:00

  • The effect of endoscopic hemostasis with alcohol on the mortality rate of nonvariceal upper gastrointestinal hemorrhage. A randomized prospective study.

    abstract::One hundred and forty-five patients with nonvariceal upper GI hemorrhage, active or with stigmata (Forrest I and II) were divided into two groups according to the day of the week on which emergency endoscopy was performed: group A (78 patients) in which conventional treatment was applied (blood transfusions, antacids,...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-1012899

    authors: Pascu O,Dräghici A,Acalovchi I

    更新日期:1989-03-01 00:00:00

  • Minimally invasive surgery.

    abstract::In 1987, Mouret performed the first laparoscopic cholecystectomy - dramatically changing the history of surgical practice. No other aspect of surgery has developed with such vigor as laparoscopy. Previously, surgeons had attempted to define the maximum level of surgical intervention a patient could withstand - but as ...

    journal_title:Endoscopy

    pub_type: 杂志文章,评审

    doi:10.1055/s-2001-13689

    authors: Rosen M,Ponsky J

    更新日期:2001-04-01 00:00:00

  • Treatment of biliary obstruction in selected patients by endoscopic ultrasonography (EUS)-guided transluminal biliary drainage.

    abstract:BACKGROUND AND STUDY AIMS:Endoscopic retrograde cholangiopancreatography (ERCP)-guided implantation of a biliary endoprosthesis or stent is the gold standard treatment for biliary obstructions. When the papilla cannot be traversed because there is pyloric or duodenal stenosis, or the catheter cannot be introduced, or b...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-966215

    authors: Will U,Thieme A,Fueldner F,Gerlach R,Wanzar I,Meyer F

    更新日期:2007-04-01 00:00:00

  • Splenic trauma during colonoscopy.

    abstract::A case of splenic rupture following therapeutic colonoscopy is described, and previously reported cases are reviewed. The occurrence of this event and the associated circumstances are often unpredictable. A high index of suspicion is the key to the diagnosis of this rare but potentially lethal complication. ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1010608

    authors: Colarian J,Alousi M,Calzada R

    更新日期:1991-01-01 00:00:00

  • Value of EUS in early detection of pancreatic ductal adenocarcinomas in patients with intraductal papillary mucinous neoplasms.

    abstract:BACKGROUND AND STUDY AIMS:Pancreatic ductal adenocarcinomas (PDAC) sometimes arise in patients with intraductal papillary mucinous neoplasms (IPMNs). This study examined the incidence of PDACs concomitant to or derived from branch duct IPMNs. The usefulness of endoscopic ultrasonography (EUS) relative to other imaging ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0033-1353603

    authors: Kamata K,Kitano M,Kudo M,Sakamoto H,Kadosaka K,Miyata T,Imai H,Maekawa K,Chikugo T,Kumano M,Hyodo T,Murakami T,Chiba Y,Takeyama Y

    更新日期:2014-01-01 00:00:00

  • Establishing transvaginal NOTES for gynecological and surgical indications: benefits, limits, and patient experience.

    abstract::Gynecologists have been performing transvaginal surgery for over a century and consequently the transvaginal approach was advocated for establishing natural orifice transluminal endoscopic surgery (NOTES) in gynecological and surgical practice. From 2008 the NOTES alternative has been offered to selected patients. Tra...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0030-1255756

    authors: Hackethal A,Sucke J,Oehmke F,Münstedt K,Padberg W,Tinneberg HR

    更新日期:2010-10-01 00:00:00

  • New development of peroral cholangioscopy--evaluation of double-angle, oblique viewing cholangioscope.

    abstract::Seven years have passed since the first report on peroral cholangioscopy by Takekoshi and Takagi (1) in Japan. Recently, several types of peroral cholangioscope with a forceps channel have been made for this treatment. However, the success rate of insertion of these instruments into the common bile duct was less than ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1018522

    authors: Fuji T,Ariyama S,Harima K,Aibe T,Amano H,Asagami F,Takemoto T

    更新日期:1984-01-01 00:00:00

  • High proximal migration rate of a partially covered "big cup" duodenal stent in patients with malignant gastric outlet obstruction.

    abstract::Endoscopic placement of self-expandable metal stents (SEMS) has emerged as a palliative treatment for patients with malignant gastric outlet obstruction (GOO). Recently, a new partially covered "big cup" SEMS has been developed to prevent both stent migration and tissue ingrowth. The aim of the study was to evaluate s...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-0033-1359023

    authors: van den Berg MW,Walter D,Vleggaar FP,Siersema PD,Fockens P,van Hooft JE

    更新日期:2014-02-01 00:00:00

  • Risk factors for inadequate bowel preparation: a validated predictive score.

    abstract::Background and study aim Inadequate bowel cleansing negatively affects the efficiency of colonoscopy in routine clinical practice. The aim of this study was to design and validate a predictive model for inadequate bowel cleanliness. Patients and methods The model was built from 667 consecutive outpatients (development...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0043-101683

    authors: Gimeno-García AZ,Baute JL,Hernandez G,Morales D,Gonzalez-Pérez CD,Nicolás-Pérez D,Alarcon-Fernández O,Jiménez A,Hernandez-Guerra M,Romero R,Alonso I,Gonzalez Y,Adrian Z,Carrillo M,Ramos L,Quintero E

    更新日期:2017-06-01 00:00:00

  • Detection of human gastric cancer in resected specimens using a novel infrared fluorescent anti-human carcinoembryonic antigen antibody with an infrared fluorescence endoscope in vitro.

    abstract:BACKGROUND AND STUDY AIMS:An indocyanine green derivative (ICG-sulfo-OSu) that can be used as an infrared fluorescent labeling substance suitable for detecting microlesions with an infrared fluorescence endoscope has been developed. The aims of the present study were to develop an infrared fluorescence endoscope and to...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2001-17328

    authors: Ito S,Muguruma N,Kusaka Y,Tadatsu M,Inayama K,Musashi Y,Yano M,Bando T,Honda H,Shimizu I,Ii K,Takesako K,Takeuchi H,Shibamura S

    更新日期:2001-10-01 00:00:00

  • Endoscopic detachable snare ligation: a new treatment method for colonic diverticular hemorrhage.

    abstract:BACKGROUND AND STUDY AIMS:Colonic diverticular hemorrhage is the most common cause of lower intestinal bleeding. We tried to develop a convenient and reliable hemostatic method, endoscopic detachable snare ligation (EDSL), to treat diverticular hemorrhage and retrospectively explored its safety and efficacy. PATIENTS ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0034-1392204

    authors: Akutsu D,Narasaka T,Wakayama M,Terasaki M,Kaneko T,Matsui H,Suzuki H,Hyodo I,Mizokami Y

    更新日期:2015-11-01 00:00:00

  • Prediction of rebleeding in peptic ulcers by visual stigmata and endoscopic Doppler ultrasound criteria.

    abstract::Following peptic ulcer hemorrhage, the ability to accurately determine those patients at highest risk of rebleeding relies on clinical and endoscopic criteria which are accurate in only a variable proportion of cases. In this study we have assessed prediction of rebleeding in peptic ulcers using a transendoscopic vasc...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1012795

    authors: Fullarton GM,Murray WR

    更新日期:1990-03-01 00:00:00

  • Role of endosonography in the surgical management of non-Hodgkin's lymphoma of the stomach.

    abstract::Ten patients with primary gastric non-Hodgkin's lymphoma (NHL) were preoperatively assessed by endoscopic ultrasonography (EUS). Tumor infiltration depth and lymph node involvement were assessed using the TNM classification system. EUS was 80% accurate in determining the TL stage and 90% in detecting lymph node metast...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1010386

    authors: Schüder G,Hildebrandt U,Kreissler-Haag D,Seitz G,Feifel G

    更新日期:1993-10-01 00:00:00