Ventricular premature beats in young subjects without evidence of cardiac disease: histological findings.

abstract：:Antithrombotic therapy and invasive risk stratification in selected high-risk patients have improved outcomes from non-ST-segment elevation acute coronary syndromes (NSTE-ACS), but carry a risk of bleeding and blood transfusion. Although the true incidence of bleeding depends on the population studied (i.e. clinical t...

journal_title：European heart journal

authors： Rao SV,Eikelboom JA,Granger CB,Harrington RA,Califf RM,Bassand JP

更新日期：2007-05-01 00:00:00

abstract：AIMS:This study was designed to characterise both the systolic and diastolic mechanical properties of regions with different degrees of myocardial ischaemic injury after reperfused acute myocardial infarction (AMI). METHODS AND RESULTS:Fourteen dogs underwent 90-min coronary artery occlusion followed by reperfusion. I...

journal_title：European heart journal

authors： Azevedo CF,Amado LC,Kraitchman DL,Gerber BL,Osman NF,Rochitte CE,Edvardsen T,Lima JA

更新日期：2004-08-01 00:00:00

abstract：AIMS:Ivabradine, a new I(f) inhibitor which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent. Ivabradine has shown anti-ischaemic and anti-anginal activity in a placebo-controlled trial. The objective of this study was to compare the anti-anginal and anti-ischaemic...

journal_title：European heart journal

authors： Tardif JC,Ford I,Tendera M,Bourassa MG,Fox K,INITIATIVE Investigators.

更新日期：2005-12-01 00:00:00

abstract：AIMS:Previous trials that investigated cell therapy as an adjunctive therapy after acute myocardial infarction (AMI) have shown conflicting results. We designed a randomized controlled trial to determine the effect of intracoronary infusion of mononuclear cells from bone marrow (BM) or peripheral blood in patients with...

journal_title：European heart journal

authors： Hirsch A,Nijveldt R,van der Vleuten PA,Tijssen JG,van der Giessen WJ,Tio RA,Waltenberger J,ten Berg JM,Doevendans PA,Aengevaeren WR,Zwaginga JJ,Biemond BJ,van Rossum AC,Piek JJ,Zijlstra F,HEBE Investigators.

更新日期：2011-07-01 00:00:00

abstract：Aims:Epidemiological studies strongly suggest a link between stress, depression, and cardiovascular diseases (CVDs); the mechanistic correlation, however, is poorly understood. A single-nucleotide polymorphism in the BDNF gene (BDNFVal66Met), associated with depression and anxiety, has been proposed as a genetic risk f...

journal_title：European heart journal

authors： Amadio P,Colombo GI,Tarantino E,Gianellini S,Ieraci A,Brioschi M,Banfi C,Werba JP,Parolari A,Lee FS,Tremoli E,Barbieri SS

更新日期：2017-05-07 00:00:00

abstract：AIMS:To compare effects of heparin and hirudin on biochemical markers of coagulation. METHODS AND RESULTS:Patients (n=395) with unstable angina or myocardial infarction without ST elevation were randomized to a 72-h infusion of one of three regimens: unfractionated heparin (bolus of 5000 IU followed by an infusion of ...

journal_title：European heart journal

authors： Flather MD,Weitz JI,Yusuf S,Pogue J,Sussex B,Campeau J,Gill J,Schuld R,Joyner CD,Morris AL,Lai C,Théroux P,Marquis JF,Chan YK,Venkatesh G,Jessel A

更新日期：2000-09-01 00:00:00

abstract：:This study has compared the effect on heart rate control of the addition of pindolol 15 mg bd or verapamil 40 mg tds to maintenance digoxin therapy in 12 patients with chronic atrial fibrillation. The study was performed in a randomized cross-over fashion. Treatment effects were assessed by 24-h ambulatory electrocard...

journal_title：European heart journal

authors： James MA,Channer KS,Papouchado M,Rees JR

更新日期：1989-01-01 00:00:00

abstract：AIMS:To estimate the incidence of dementia after the first atrial fibrillation (AF), and its impact on survival in a community-based cohort. METHODS AND RESULTS:Olmsted County, Minnesota adult residents diagnosed with first AF during 1986-2000 were identified, and followed until 2004. The primary outcome was new detec...

journal_title：European heart journal

authors： Miyasaka Y,Barnes ME,Petersen RC,Cha SS,Bailey KR,Gersh BJ,Casaclang-Verzosa G,Abhayaratna WP,Seward JB,Iwasaka T,Tsang TS

更新日期：2007-08-01 00:00:00

abstract：:Coronary vasodilator responses to pharmacological (acetylcholine) and physiological (cold pressor test and flow dependent dilation) stimuli are impaired in hypertensive patients. The ability of angiotensin-converting enzyme inhibitors to restore normal coronary responses in hypertension and the potential mechanisms in...

journal_title：European heart journal

authors： Nitenberg A,Antony I

更新日期：1998-09-01 00:00:00

abstract：AIMS:There is little evidence to inform routine practice in the use of coronary angiography and revascularization procedures after acute myocardial infarction. Large differences in the uptake of these procedures have been reported but representative data are scarce. Outcome studies have produced opposing conclusions co...

journal_title：European heart journal

authors： Woods KL,Ketley D,Agusti A,Hagn C,Kala R,Karatzas NB,Leizorowicz A,Reikvam A,Schilling J,Seabra-Gomes R,Vasiliauskas D,Wilhelmsen L

更新日期：1998-09-01 00:00:00

abstract：:To study the haemodynamic and neurohumoral effects of nisoldipine (2 X 10 mg) vs captopril (3 X 25 mg), 24 patients with heart failure (New York Heart Association class II and III) due to coronary artery disease were treated in a randomized double-blind trial over 3 months. Both drugs were well tolerated. Clinical sta...

journal_title：European heart journal

authors： Schofer J,Hobuss M,Aschenberg W,Tews A

更新日期：1990-08-01 00:00:00

abstract：AIMS:Adults who engage in leisure-time physical activity (LTPA) have a reduced risk of developing heart failure. We hypothesized that high levels of LTPA are associated with diminished adverse age-related changes in cardiac structure and function. METHODS AND RESULTS:We studied 4342 Atherosclerosis Risk in Communities...

journal_title：European heart journal

authors： Hegde SM,Gonçalves A,Claggett B,Evenson KR,Cheng S,Shah AM,Folsom AR,Solomon SD

更新日期：2016-08-21 00:00:00

abstract：AIMS:To investigate the subacute effects of a sustained intravenous infusion of urocortin-I (Ucn-I) in experimental heart failure (HF). METHODS AND RESULTS:In eight sheep with pacing-induced HF, a 4-day infusion of Ucn-I (0.3 microg/kg/h) induced prompt (30 min) and sustained (4-day) increases in cardiac output (CO, D...

journal_title：European heart journal

authors： Rademaker MT,Charles CJ,Espiner EA,Frampton CM,Lainchbury JG,Richards AM

更新日期：2005-10-01 00:00:00

abstract：AIMS:We aimed to assess the increased risk of death and severe vascular events in elderly individuals with subclinical or manifest peripheral arterial disease (PAD), evidenced by low ankle brachial index (ABI < 0.9) in primary care. METHODS AND RESULTS:In this monitored prospective observational study, 6880 representa...

journal_title：European heart journal

authors： Diehm C,Lange S,Darius H,Pittrow D,von Stritzky B,Tepohl G,Haberl RL,Allenberg JR,Dasch B,Trampisch HJ

更新日期：2006-07-01 00:00:00

abstract：AIMS:A new generation of multidetector-row CT (MDCT) scanners allows complete coronary coverage using retrospective ECG gating and 1mm slices. The purpose of this study was to investigate the potential of high resolution MDCT angiography with retrospective gating for detection of coronary artery stenoses. METHODS AND ...

journal_title：European heart journal

authors： Kopp AF,Schroeder S,Kuettner A,Baumbach A,Georg C,Kuzo R,Heuschmid M,Ohnesorge B,Karsch KR,Claussen CD

更新日期：2002-11-01 00:00:00

abstract：AIMS:We hypothesized that chronic heart failure as a model of systemic hypoxia may result in systemic inflammation. The signs of a systemic inflammatory response should disappear after successful mechanical circulatory support using biventricular assist device systems. METHODS AND RESULTS:Plasma levels of cytokines (I...

journal_title：European heart journal

authors： Hasper D,Hummel M,Kleber FX,Reindl I,Volk HD

更新日期：1998-05-01 00:00:00

abstract：AIMS:Although cerebral blood flow (CBF) is known to be low in patients with advanced systolic heart failure (HF), little is known of the prognostic significance of this observation. We investigated whether CBF might be associated with the development of adverse outcomes in systolic HF, and whether it might provide prog...

journal_title：European heart journal

authors： Kim MS,Kim JS,Yun SC,Lee CW,Song JK,Park SW,Park SJ,Kim JJ

更新日期：2012-02-01 00:00:00

abstract：AIMS:Our objective was to create a simple prognostic risk score for patients with systolic heart failure and mild symptoms. We then assessed the efficacy of eplerenone across different categories of risk. METHODS AND RESULTS:The Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure trial (EMP...

journal_title：European heart journal

authors： Collier TJ,Pocock SJ,McMurray JJ,Zannad F,Krum H,van Veldhuisen DJ,Swedberg K,Shi H,Vincent J,Pitt B

更新日期：2013-09-01 00:00:00

abstract：AIM:To define the long-term outcome of patients presenting with acute coronary syndrome [ST-segment elevation myocardial infarction (STEMI), and non-STEMI and unstable angina acute coronary syndrome (ACS) without biomarker elevation] and to test the hypothesis that the GRACE (Global Registry of Acute Coronary Events) r...

journal_title：European heart journal

authors： Fox KA,Carruthers KF,Dunbar DR,Graham C,Manning JR,De Raedt H,Buysschaert I,Lambrechts D,Van de Werf F

更新日期：2010-11-01 00:00:00

abstract：:The concentration of cholesterol in peripheral lymph is roughly one tenth of that in the blood plasma of the same subject. In lymph, there is virtually no very low density lipoprotein (VLDL), probably due to low permeability of the vascular endothelium for particles of this size. More than 95% of apo B-containing lipo...

journal_title：European heart journal

authors： Reichl D

更新日期：1990-08-01 00:00:00

abstract：:Clinical studies suggest that neutrophil activation during acute myocardial infarction (MI) aggravates tissue injury. Activated neutrophils are an important source of oxygen free radicals (OFR), the injurious effects of which are counteracted by endogenous antioxidants. We have previously shown in healthy subjects tha...

journal_title：European heart journal

authors： Herbaczyńska-Cedro K,K+osiewicz-Wasek B,Cedro K,Wasek W,Panczenko-Kresowska B,Wartanowicz M

更新日期：1995-08-01 00:00:00

abstract：:This report describes a patient with left atrial ball thrombus which was detected during echocardiographic evaluation of combined mitral-aortic valve disease. Surgical correction was performed entirely on the basis of the echocardiographic diagnosis. ...

journal_title：European heart journal

authors： Schäfer RO,Evers G,Morgan P,Thiel H

更新日期：1992-02-01 00:00:00

abstract：AIMS:Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a key regulator of extracellular matrix degradation. We examined relations of plasma total TIMP-1 to cardiovascular risk factors and echocardiographic left ventricular (LV) structure and function in a community-based sample. METHODS AND RESULTS:We studied 1069 ...

journal_title：European heart journal

authors： Sundström J,Evans JC,Benjamin EJ,Levy D,Larson MG,Sawyer DB,Siwik DA,Colucci WS,Wilson PW,Vasan RS

更新日期：2004-09-01 00:00:00

abstract：Aims:Congenital heart defects (CHD) affect almost 1% of all live born children and the number of adults with CHD is increasing. In families where CHD has occurred previously, estimates of recurrence risk, and the type of recurring malformation are important for counselling and clinical decision-making, but the recurren...

journal_title：European heart journal

authors： Ellesøe SG,Workman CT,Bouvagnet P,Loffredo CA,McBride KL,Hinton RB,van Engelen K,Gertsen EC,Mulder BJM,Postma AV,Anderson RH,Hjortdal VE,Brunak S,Larsen LA

更新日期：2018-03-21 00:00:00

abstract：AIMS:Reperfusion injury following acute myocardial infarction impacts not only on the myocardium but also on the coronary microcirculation, and microembolization from the culprit lesion contributes to microvascular obstruction. Prior experimental studies have not accounted for microembolization in ischaemia/reperfusion...

journal_title：European heart journal

authors： Skyschally A,Walter B,Heusch G

更新日期：2013-11-01 00:00:00

abstract：:Physical fitness of athletes affected by mitral valve prolapse (MVP) was examined, in order to evaluate the influence of sport activity on the natural history of the disease. Maximal workload, total workload, percentage efficiency (according to Hollmann's formula), double product of maximal cycloergometric stress test...

journal_title：European heart journal

authors： Musante R,Cupelli V,Mori F,Attinà DA

更新日期：1987-08-01 00:00:00

abstract：AIMS:Anticancer therapies have extended the lives of millions of patients with malignancies, but for some this benefit is tempered by adverse cardiovascular (CV) effects. Cardiotoxicity may occur early or late after treatment initiation or termination. The extent of this cardiotoxicity is variable, depending on the typ...

journal_title：European heart journal

authors： Lancellotti P,Suter TM,López-Fernández T,Galderisi M,Lyon AR,Van der Meer P,Cohen Solal A,Zamorano JL,Jerusalem G,Moonen M,Aboyans V,Bax JJ,Asteggiano R

更新日期：2019-06-07 00:00:00

abstract：:The diagnosis and management of patients with renovascular disease and hypertension continue to elude healthcare providers. The advent of novel imaging and interventional techniques, and increased understanding of the pathways leading to irreversible renal injury and renovascular hypertension, have ushered in commenda...

journal_title：European heart journal

authors： Baumgartner I,Lerman LO

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to describe the frequencies of various diagnoses in patients admitted with acute chest pain, but without acute myocardial infarction, and to evaluate a non-invasive screening programme for these patients. PATIENTS:A total of 204 consecutive non-acute myocardial infarction patien...

journal_title：European heart journal

authors： Fruergaard P,Launbjerg J,Hesse B,Jørgensen F,Petri A,Eiken P,Aggestrup S,Elsborg L,Mellemgaard K

更新日期：1996-07-01 00:00:00

abstract：AIMS:To investigate the effects of secretory phospholipase A2 (sPLA(2)) inhibition on plasma lipoproteins. Secretory phospholipase A2 isoenzymes promote atherosclerosis by mechanisms that include lipoprotein modification, retention, and oxidation. METHODS AND RESULTS:Phospholipase Levels And Serological Markers of Ath...

journal_title：European heart journal

authors： Rosenson RS,Elliott M,Stasiv Y,Hislop C,PLASMA II Investigators.

更新日期：2011-04-01 00:00:00