Effects of oxygen supply on the production of nikkomycin with immobilized cells of Streptomyces tendae.

abstract：:In a screening for proteolytically active lactic acid bacteria, three strains, Lactobacillus delbrueckii ssp. lactis 92202, Lactobacillus helveticus 92201, and Lactobacillus delbrueckii ssp. bulgaricus 92059, showed the highest activities following growth in milk. All three strains degraded α- and β-casein, but did no...

journal_title：Applied microbiology and biotechnology

authors： Kliche T,Li B,Bockelmann W,Habermann D,Klempt M,de Vrese M,Wutkowski A,Clawin-Raedecker I,Heller KJ

更新日期：2017-10-01 00:00:00

abstract：:Cyanobacterial mutants defective in acyl-acyl carrier protein synthetase (Aas) secrete free fatty acids (FFAs) into the external medium and hence have been used for the studies aimed at photosynthetic production of biofuels. While the wild-type strain of Synechocystis sp. PCC 6803 is highly sensitive to exogenously ad...

journal_title：Applied microbiology and biotechnology

authors： Kojima K,Keta S,Uesaka K,Kato A,Takatani N,Ihara K,Omata T,Aichi M

更新日期：2016-12-01 00:00:00

abstract：:Oils and fats are the most important renewable raw materials of the chemical industry. They make available fatty acids in such purity that they may be used for chemical conversions and for the synthesis of chemically pure compounds. Oleic acid (1) from "new sunflower," linoleic acid (2) from soybean, linolenic acid (3...

journal_title：Applied microbiology and biotechnology

authors： Metzger JO,Bornscheuer U

更新日期：2006-06-01 00:00:00

abstract：:Shewanella decolorationis S12, a representative dissimilatory azo-reducing bacterium of Shewanella genus, can grow by coupling the oxidation of hydrogen to the reduction of azo compounds as the sole electron acceptor, indicating that an uptake hydrogenase is an important component for electron transfer for azoreductio...

journal_title：Applied microbiology and biotechnology

authors： Hong YG,Guo J,Sun GP

更新日期：2008-09-01 00:00:00

abstract：:The six- and seven-subunit Na+/H+ antiporters (Mrp) are widely distributed in bacteria. They are reported to be integral for pH homeostasis in alkaliphilic bacteria when adapting to high pH environments. In this study, operons encoding for the six-subunit Na+/H+ antiporters were found in the genomes of all studied Die...

journal_title：Applied microbiology and biotechnology

authors： Fang H,Qin XY,Zhang KD,Nie Y,Wu XL

更新日期：2018-04-01 00:00:00

abstract：:The use of antibiotics may accelerate the development of antibiotic resistance genes (ARGs) and bacteria which shade health risks to humans and animals. The emerging of ARGs in the water environment is becoming an increasing worldwide concern. Hundreds of various ARGs encoding resistance to a broad range of antibiotic...

journal_title：Applied microbiology and biotechnology

authors： Zhang XX,Zhang T,Fang HH

更新日期：2009-03-01 00:00:00

abstract：:The genetic improvement of winemaking yeasts is a virtually infinite process, as the design of new strains must always cope with varied and ever-evolving production contexts. Good wine yeasts must feature both good primary traits, which are related to the overall fermentative fitness of the strain, and secondary trait...

journal_title：Applied microbiology and biotechnology

authors： Bonciani T,De Vero L,Mezzetti F,Fay JC,Giudici P

更新日期：2018-03-01 00:00:00

abstract：:Seasonal shifts of dissolved inorganic nitrogen (DIN) and the dynamics of microbial communities for nitrogen transformation were investigated in the water column of Chesapeake Bay. The relative abundance of nitrogen over phosphorus (N) showed a strong seasonal and spatial pattern: gradually decreased from upstream to ...

journal_title：Applied microbiology and biotechnology

authors： Hong Y,Xu X,Kan J,Chen F

更新日期：2014-04-01 00:00:00

abstract：:A gene for a synthetic protein-based polymer, G-(VPGVG)119-VPGV, coding for the EG-120mer (elastomer), was cloned into a fungal expression vector to allow constitutive expression of the polymer controlled by the gpdA (glyceraldehyde-3-phosphate dehydrogenase) promoter sequence of Aspergillus nidulans. Stable transform...

journal_title：Applied microbiology and biotechnology

authors： Herzog RW,Singh NK,Urry DW,Daniell H

更新日期：1997-04-01 00:00:00

abstract：:The polyene macrolide rimocidin, produced by Streptomyces rimosus M527, is highly effective against a broad range of fungal plant pathogens, but at low yields. Elicitation is an effective method of stimulating the yield of bioactive secondary metabolites. In this study, the biomass and filtrate of a culture broth of E...

journal_title：Applied microbiology and biotechnology

authors： Song Z,Ma Z,Bechthold A,Yu X

更新日期：2020-05-01 00:00:00

abstract：:Certain lactic acid bacteria, especially heterofermentative strains, are capable to produce mannitol under adequate culture conditions. In this study, mannitol production by Lactobacillus reuteri CRL 1101 and Lactobacillus fermentum CRL 573 in modified MRS medium containing a mixture of fructose and glucose in a 6.5:1...

journal_title：Applied microbiology and biotechnology

authors： Rodríguez C,Rimaux T,Fornaguera MJ,Vrancken G,de Valdez GF,De Vuyst L,Mozzi F

更新日期：2012-03-01 00:00:00

abstract：:(S)-Hydroxynitrile lyase from Manihot esculenta (MeHNL) was shown for the first time to be able to catalyze the enantioselective transcyanation of acetyltrimethylsilane (ATMS) with acetone cyanohydrin to form (S)-2-trimethylsilyl-2-hydroxyl-propionitrile in an aqueous/organic biphasic system. To better understand the ...

journal_title：Applied microbiology and biotechnology

authors： Xu R,Zong MH,Liu YY,He J,Zhang YY,Lou WY

更新日期：2004-11-01 00:00:00

abstract：:Cytophaga hutchinsonii is a Gram-negative aerobic soil bacterium which can digest crystalline cellulose completely through a strategy different from that of the well-studied cellulolytic aerobic fungi and anaerobic bacteria. However, despite the availability of a published genome sequence, studies on this organism hav...

journal_title：Applied microbiology and biotechnology

authors： Xu Y,Ji X,Chen N,Li P,Liu W,Lu X

更新日期：2012-01-01 00:00:00

abstract：:Myxobacteria are Gram-negative soil microorganisms that prey on other microorganisms. Myxobacteria have significant potential for applications in biotechnology because of their extraordinary ability to produce natural products such as secondary metabolites. Myxobacteria also stand out as model organisms for the study ...

journal_title：Applied microbiology and biotechnology

authors： Ueki T,Inouye S

更新日期：2006-08-01 00:00:00

abstract：:The amino acid analogue selenomethionine (SeMet) is shown to be efficiently incorporated into recombinant proteins expressed in Escherichia coli grown in a simple minimal medium without the addition of synthetic amino acids. Furthermore, satisfactory SeMet incorporation is obtained with a methionine-prototrophic strai...

journal_title：Applied microbiology and biotechnology

authors： Guerrero SA,Hecht HJ,Hofmann B,Biebl H,Singh M

更新日期：2001-09-01 00:00:00

abstract：:The main carbohydrate of red macroalgae is agarose, a heterogeneous polysaccharide composed of D-galactose and 3,6-anhydro-L-galactose. When saccharifying agarose by enzymes, the unique physical properties of agarose, namely the sol-gel transition and the near-insolubility of agarose in water, limit the accessibility ...

journal_title：Applied microbiology and biotechnology

authors： Kim JH,Yun EJ,Seo N,Yu S,Kim DH,Cho KM,An HJ,Kim JH,Choi IG,Kim KH

更新日期：2017-02-01 00:00:00

abstract：:Nanosized elemental sulfur (ES) is already reported to exert superior antimicrobial efficacy than micron-sized ES, which encourages their use in drugs and therapeutics. The aim of the present study is to explore the possible route and mode of antimicrobial action of orthorhombic (α-SNPs) and monoclinic (β-SNPs) allotr...

journal_title：Applied microbiology and biotechnology

authors： Roy Choudhury S,Mandal A,Ghosh M,Basu S,Chakravorty D,Goswami A

更新日期：2013-07-01 00:00:00

abstract：:Cyclosporin A (CyA) has received meticulous attention owing to its immunosuppressive and biological activities. In this study, a soil isolate, capable of producing CyA, was named Zag1 strain and identified as Aspergillus fumigatus based on macroscopic and microscopic characteristics, 18S rDNA sequence, and phylogeneti...

journal_title：Applied microbiology and biotechnology

authors： Ismaiel AA

更新日期：2017-04-01 00:00:00

abstract：:A purification procedure for an extracellular alpha-amylase from Streptomyces rimosus, oxytetracycline-producing strain, is described. The enzyme obtained was shown to be an acidic (pI 4.75) monomer with a relative molecular mass (M(r)) of 43,000, containing three cysteines involved in the catalytic activity of the en...

journal_title：Applied microbiology and biotechnology

authors： Vukelić B,Ritonja A,Renko M,Pokorny M,Vitale L

更新日期：1992-05-01 00:00:00

abstract：:Pichia pastoris is widely used as a host system for heterologous protein expression in both academia and industry. Production is typically accomplished by a fed-batch induction process that is known to have negative impacts on cell physiology that impose limits on both protein yields and quality. We have analysed reco...

journal_title：Applied microbiology and biotechnology

authors： Hesketh AR,Castrillo JI,Sawyer T,Archer DB,Oliver SG

更新日期：2013-11-01 00:00:00

abstract：:Confident protein-DNA interaction (PDI) data could significantly improve our understanding of transcriptional regulation network in both prokaryotes and eukaryotes. New methods need to be established for validating and mining the protein-DNA interaction data produced by bioinformatic tools and large-scale screening as...

journal_title：Applied microbiology and biotechnology

authors： Zeng J,Li Y,Zhang S,He ZG

更新日期：2012-02-01 00:00:00

abstract：:Two novel cyclic hexapeptides designated actinosynneptides A (1) and B (2), together with three tryptophan containing diketopiperazines, namely cyclo(L-Trp-L-Trp) (3), cyclo(L-Trp-N-MeL-Trp) (4), and cyclo(N-MeL-Trp-N-MeL-Trp) (5), were isolated from the culture of the genetically engineered strain HGF052::asm18 deriv...

journal_title：Applied microbiology and biotechnology

authors： Lu C,Xie F,Shan C,Shen Y

更新日期：2017-03-01 00:00:00

abstract：:A set of filamentous fungi (42 strains) was screened for alpha-N-acetylgalactosaminidase activity, and a series of inducers and different cultivation conditions were tested. Enzyme production by the best producer Aspergillus niger CCIM K2 was optimized and scaled up. alpha-N-Acetylgalactosaminidase was purified to app...

journal_title：Applied microbiology and biotechnology

authors： Weignerová L,Filipi T,Manglová D,Kren V

更新日期：2008-07-01 00:00:00

abstract：:Escherichia coli BL21, expressing a quintuple mutant of P450(BM-3), oxyfunctionalizes alpha-pinene in an NADPH-dependent reaction to alpha-pinene oxide, verbenol, and myrtenol. We optimized the whole-cell biocatalyst by integrating a recombinant intracellular NADPH regeneration system through co-expression of a glucos...

journal_title：Applied microbiology and biotechnology

authors： Schewe H,Kaup BA,Schrader J

更新日期：2008-02-01 00:00:00

abstract：:Phosphate is one of the major constituents in growth media. It closely regulates central carbon and energy metabolism. Biochemical reactions in central carbon metabolism are known to be regulated by phosphorylation and dephosphorylation of enzymes. Phosphate scarcity can limit microbial productivity. However, microorg...

journal_title：Applied microbiology and biotechnology

authors： Pandi K,Chauhan AS,Khan WH,Rathore AS

更新日期：2020-11-01 00:00:00

abstract：:Spillage of fossil-based oils during their conveyance through water conduits are sporadic, but significant environmental disasters. As the viscous hydrocarbons of the crude oils spread on water surface and choke aquatic life to death, their effective degradation is crucial for ecological balance. Though chemical and m...

journal_title：Applied microbiology and biotechnology

authors： Patel S,Homaei A,Patil S,Daverey A

更新日期：2019-01-01 00:00:00

abstract：:The phylum Basidiomycota includes filamentous fungi and yeast species with different ecological and genomic characteristics. Transposable elements (TEs) are abundant components of most eukaryotic genomes, and their transition from being genomic parasites to key drivers of genomic architecture, functionality, and evolu...

journal_title：Applied microbiology and biotechnology

authors： Castanera R,Borgognone A,Pisabarro AG,Ramírez L

更新日期：2017-02-01 00:00:00

abstract：:A reactive iron barrier in a contaminated aquifer with low pH was found to dechlorinate 1,2-dichloroethane (1,2-DCA) in situ. This chlorinated ethane is known to resist abiotic reduction by zero valent iron. Samples taken up-gradient and within the barrier were used to inoculate anaerobic batch cultures amended with v...

journal_title：Applied microbiology and biotechnology

authors： Zemb O,Lee M,Low A,Manefield M

更新日期：2010-09-01 00:00:00

abstract：:Herein, we present data demonstrating that the application of initial cell culture enrichment could significantly improve mycoplasma testing methods based on the nucleic acid amplification technology (NAT) including a polymerase chain reaction (PCR)/microarray method. The results of the study using Vero cells demonstr...

journal_title：Applied microbiology and biotechnology

authors： Kong H,Volokhov DV,George J,Ikonomi P,Chandler D,Anderson C,Chizhikov V

更新日期：2007-11-01 00:00:00

abstract：:Mycelial adhesion affects cell growth and the production of water-soluble extracellular yellow pigment (EYP) in submerged fermentation with Monascus ruber CGMCC 10910. Two nitrates, NaNO3 and KNO3, were used as nitrogen sources for mitigating mycelial adhesion and improving the production of EYP in this study. The res...

journal_title：Applied microbiology and biotechnology

authors： Yang SZ,Huang ZF,Liu HQ,Hu X,Wu ZQ

更新日期：2020-11-01 00:00:00