Quantitative analysis of Langerhans' cells in epidermis at irritant contact reactions using confocal laser scanning microscopy.

abstract：:Blood levels of serotonin (5-HT) and urinary excretion of 5-hydroxyindole-acetic acid (5-HIAA), tryptamine (T), and indole-acetic acid (IAA) were determined in 39 cases of systemic scleroderma and in 7 cases of very severe cutaneous scleroderma. The T/IAA ratio was normal and serotonin elevated in mild and rather seve...

journal_title：Acta dermato-venereologica

authors： Stachów A,Jabłońska S,Skiendzielewska A

更新日期：1979-01-01 00:00:00

abstract：:A skin biopsy is one of the most frequently performed procedures in the dermatology outpatient clinic, but doctors often do not consider the cognitive impact of the biopsy procedure. Based on "terror management theory," we reasoned that a skin biopsy increases patient compliance by unconsciously stimulating mortality ...

journal_title：Acta dermato-venereologica

authors： Kim JH,Kim J,Jung YH,Yi Y,Ahn HH

更新日期：2010-05-01 00:00:00

abstract：:During the years 1977-1986 five patients were referred to the Department of Plastic Surgery. University Hospital, Arhus, for treatment of carcinomas occurring in the skin on the sites previously treated with Grenz rays for benign dermatoses. Grenz ray treatment had been given for eight to nineteen years. The dose give...

journal_title：Acta dermato-venereologica

authors： Mortensen AC,Kjeldsen H

更新日期：1987-01-01 00:00:00

abstract：:In order to study the flare-up of contact allergy, 35 patients with a contact allergy to gold were given an intramuscular injection of 10 mg gold sodium thiomalate, i.e. the anti-rheumatic drug Myocrisin. Clinical reactions comprised an eczematous flare-up of previously positive patch tests to gold and of a previous d...

journal_title：Acta dermato-venereologica

authors： Möller H

更新日期：2000-03-01 00:00:00

abstract：:Lymphocytes from 8 patients with contact dermatitis and a positive nickel patch test, 7 patients with contact dermatitis due to other factors and with a negative nickel patch test, and 9 other subjects, 7 of whom suffered from other dermatological disorders, were tested with the lymphocyte transformation test (LTT), u...

journal_title：Acta dermato-venereologica

authors： Svejgaard E,Morling N,Svejgaard A,Veien NK

更新日期：1978-01-01 00:00:00

abstract：:Atopic dermatitis is a common skin disorder of unknown aetiology with peak incidence in early childhood. The disease is associated with peripheral T-cell accumulation in the skin. The thymus is a key organ of the cellular immune response early in life. We hypothesized that atopic dermatitis is associated with an unbal...

journal_title：Acta dermato-venereologica

authors： Olesen AB,Andersen G,Jeppesen DL,Benn CS,Juul S,Thestrup-Pedersen K

更新日期：2005-01-01 00:00:00

abstract：:A 45-year-old woman with solar urticaria is described. She was found to have: (a) increase of skin mast cells; (b) a good therapeutic response to hydroxyzine hydrochloride; (c) frequent peptic ulcers of the stomach; (d) antinuclear IgM antibodies in a titre of 1 : 1 000; (e) cold urticaria and dermographism; (f) anamn...

journal_title：Acta dermato-venereologica

authors： Rantanen T,Suhonen R

更新日期：1980-01-01 00:00:00

abstract：:Regulatory T cells (Tregs), identified by the expression of CD4, CD25 and Foxp3, together with immunosuppressive macrophages, such as CD163+ M2 macrophages, are involved in maintaining peripheral tolerance. The aim of this study was to elucidate the involvement of Tregs and CD163+ macrophages in invasive and non-invas...

journal_title：Acta dermato-venereologica

authors： Fujimura T,Kambayashi Y,Hidaka T,Hashimoto A,Haga T,Aiba S

更新日期：2012-11-01 00:00:00

abstract：:The biosynthesis of prostaglandins by human inflamed skin was studied in 8 patients with primary irritant dermatitis induced by benzalconium-chloride. Inflamed skin from these patients evidenced an increased ability to synthesize prostaglandins. In the presence of exogenous arachidonic acid in the incubation medium, t...

journal_title：Acta dermato-venereologica

authors： Jorgensen HP,Sondergaard J

更新日期：1976-01-01 00:00:00

abstract：:A female presenting multiple osteoma cutis lesions without underlying endocrinological disturbance was studied. Histologically, lesions revealed true bone formation with multiple osteoblastic cells. This was confirmed by demonstrating high alkaline phosphatase activity and osteonectin expression in osteoma cutis lesio...

journal_title：Acta dermato-venereologica

authors： Oikarinen A,Tuomi ML,Kallionen M,Sandberg M,Väänänen K

更新日期：1992-01-01 00:00:00

abstract：:Confounding from comorbidity and socioeconomic status may have biased earlier findings of all-cause mortality among patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). We therefore examined all-cause mortality among 72,295 Danish patients with BCC, 11,601 with SCC, and 383,714 age- and gender-m...

journal_title：Acta dermato-venereologica

authors： Jensen AØ,Lamberg AL,Jacobsen JB,Braae Olesen A,Sørensen HT

更新日期：2010-07-01 00:00:00

abstract：:Cutaneous leishmaniasis poses a therapeutic challenge in the paediatric population. The aim of this study was to assess the efficacy and safety of miltefosine treatment for Old World cutaneous leishmaniasis in paediatric patients. A multicentre retrospective review of 10 children (≤ 18 years of age) with cutaneous lei...

journal_title：Acta dermato-venereologica

authors： Ollech A,Solomon M,Horev A,Reiss-Huss S,Ben-Amitai D,Zvulunov A,Friedland R,Atar-Snir V,Molho-Pessach V,Barzilai A,Greenberger S

更新日期：2020-10-19 00:00:00

abstract：:Although recent therapeutic developments raise hope, melanoma remains a devastating disease with a need for new treatment targets. In other tumours prohormone convertases have been shown to be pro-tumourigenic as they are involved in processing preforms of matrix-metalloproteinases, growth factors and adhesion molecul...

journal_title：Acta dermato-venereologica

authors： Weishaupt C,Mastrofrancesco A,Metze D,Kemper B,Stegemann A,Picardo M,Klein-Szanto AJP,Böhm M

更新日期：2020-05-28 00:00:00

abstract：:Although pruritus is an essential symptom of atopic dermatitis, its complex pathomechanism is not fully understood. The aim of this study was to characterize the clinical pattern of itch in adult subjects with atopic dermatitis. A total of 89 patients (59 females, 30 males) with atopic dermatitis, age range 18-60 year...

journal_title：Acta dermato-venereologica

authors： Chrostowska-Plak D,Salomon J,Reich A,Szepietowski JC

更新日期：2009-01-01 00:00:00

abstract：:Halo naevi are considered benign. They occur in children and adolescents. Eruptive multiple halo naevi are infrequently seen in adults. The first patient in this case series had previously had melanoma. Positron emission tomography-computed tomography (PET-CT) showed a papillary thyroid carcinoma. Subsequent adult pat...

journal_title：Acta dermato-venereologica

authors： Lorentzen HF

更新日期：2020-08-17 00:00:00

abstract：:Urinary excretion of proline and hydroxyproline was studied in five groups of subjects, viz. controls, pituitary dwarfs, familial dwarfs, patients with fibrodysplasia ossificans progressive and patients with generalized scleroderma. The ratio Pro/Hyp in the urinary fraction precipitated with 5 parts of acetone (1 + 5 ...

journal_title：Acta dermato-venereologica

authors： Blumenkrantz N,Howitz P,Asboe-Hansen G

更新日期：1979-01-01 00:00:00

abstract：:The effect on dermographic wealing of an H1 and H2 receptor antagonist was studied separately and in combination. a double-blind protocol was used and dermographism was measured as the diameter of weal response to a measured force. Both H1 and H2 antagonists had a small but non-significant effect, but the combination ...

journal_title：Acta dermato-venereologica

authors： Cook J,Shuster S

更新日期：1983-01-01 00:00:00

abstract：:Most dermatologists are aware of the benefits of dermoscopy, and a few are familiar with laser-scanning confocal microscopy. Beyond confocal, there are fully 11 different categories of optical techniques that have been applied to clinical dermatology. This article first provides a comprehensive tabular overview of all...

journal_title：Acta dermato-venereologica

authors： Tkaczyk E

更新日期：2017-01-01 00:00:00

abstract：:Thirty psoriatic out-patients were treated as a right-left comparison with dithranol (0.1, 0.5, 1, 2%) and butantrone (0.66, 1.3, 2.7, 3.9%) short contact therapy, both in white petrolatum. Fifteen of the treated patients cleared well and no obvious differences between the treated sides were clinically observed. Six p...

journal_title：Acta dermato-venereologica

authors： Göransson A

更新日期：1987-01-01 00:00:00

abstract：:Localized heat urticaria is a rare disorder, in which the nature of the mediator is not fully established. We report the case of a 41-year-old woman with the condition, dependent upon mast cell integrity, in which histamine was demonstrated as the dominant, if not sole mediator. Non-sedative antihistamines conferred s...

journal_title：Acta dermato-venereologica

authors： Higgins EM,Friedmann PS

更新日期：1991-01-01 00:00:00

abstract：:Eosinophilic pustular folliculitis is a rare dermatosis. Recently, in addition to oral indomethacin, other treatments have been applied for eosinophilic pustular folliculitis. The aim of this study was to assess the effectiveness of various therapies encompassing conventional to newly applied drugs for eosinophilic pu...

journal_title：Acta dermato-venereologica

authors： Fukamachi S,Kabashima K,Sugita K,Kobayashi M,Tokura Y

更新日期：2009-01-01 00:00:00

abstract：:The proportions of suppressor T cells (TG) and helper T cells (TM) were determined in 5 patients with Mycosis fungoides (MF), 4 patients with parapsoriasis en plaques/poikiloderma atrophicans vasculare and 3 patients with generalized chronic dermatitis. All the MF patients showed increased proportions of suppressor T ...

journal_title：Acta dermato-venereologica

authors： Wassermann J,Biberfeld G,Baral E,Blomgren H,Thyresson N,Brehmer-Andersson E

更新日期：1980-01-01 00:00:00

abstract：:Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesions were evaluated fo...

journal_title：Acta dermato-venereologica

authors： Tschandl P,Gambardella A,Boespflug A,Deinlein T,de Giorgi V,Kittler H,Lallas A,Malvehy J,Moscarella E,Puig S,Scalvenzi M,Thomas L,Zalaudek I,Alfano R,Argenziano G

更新日期：2017-11-15 00:00:00

abstract：:Thirty lightly pigmented hairless (Hr/Hr) mice were irradiated 5 days per week for 30 weeks to assess the photocarcinogenicity of a new Philips TL 01 narrow-band (311 nm +/- 2) UVB lamp. All mice were found to be tumour-bearing after 16 weeks and histologically, 83% of these had definite squamous cell carcinomas. Comp...

journal_title：Acta dermato-venereologica

authors： Flindt-Hansen H,McFadden N,Eeg-Larsen T,Thune P

更新日期：1991-01-01 00:00:00

abstract：:Erythema elevatum diutinum (EED) is a chronic disease with symmetrical persistent erythematous nodules and plaques primarily in an acral distribution. EED is often associated with infections, especially of streptococcals. An immunological reaction has been proposed as pathogenetic mechanism. We describe a patient, who...

journal_title：Acta dermato-venereologica

authors： da Cunha Bang F,Weismann K,Ralfkiaer E,Pallesen G,Lange Wantzin G

更新日期：1986-01-01 00:00:00

abstract：:BRAF and NRAS genetic analyses are time-consuming and can delay treatment choices in patients with metastatic melanomas presenting with acute deterioration. We compared the rapid, real-time, fully automated molecular diagnosis platform Idylla™ with next-generation sequencing (NGS) and immunohistochemistry for detectio...

journal_title：Acta dermato-venereologica

authors： Barel F,Guibourg B,Lambros L,Le Flahec G,Marcorelles P,Uguen A

更新日期：2018-01-12 00:00:00

abstract：:This hitherto unknown and dominantly inherited disorder is characterized by vermiculate atrophoderma, milia, hypotrichosis, trichoepitheliomas, basal cell carcinomas and peripheral vasodilation with cyanosis. It has been present in the family reported for at least four generations. The lesions become visible in late c...

journal_title：Acta dermato-venereologica

authors： Michaëlsson G,Olsson E,Westermark P

更新日期：1981-01-01 00:00:00

abstract：:A report is given of the successful treatment with transfer factor as an additional therapeutic agent of a patient in the tumour stage of mycosis fungoides who had not responded to conventional treatment with nitrogen mustard, methotrexate, or grenz rays alone. Besides twelve injections of transfer factor, the patient...

journal_title：Acta dermato-venereologica

authors： Zachariae H,Grunnet E,Thestrup-Pedersen K

更新日期：1979-01-01 00:00:00

abstract：:Anisakis simplex is a seafish nematode, which is responsible for the well-known human infection (anisakiasis) and can induce IgE-mediated reactions. IgE sensitization to Anisakis simplex can be frequent in particular countries and should be suspected in patients with acute allergic symptoms after ingestion of fish. Th...

journal_title：Acta dermato-venereologica

authors： Foti C,Nettis E,Cassano N,Di Mundo I,Vena GA

更新日期：2002-01-01 00:00:00

abstract：:Eye colour, hair colour and skin colour are important risk factors for malignant melanoma and non-melanoma skin cancers. There are few studies in which the distribution of these pigmentary factors in risk populations has been assessed. The purpose of this study was to investigate the prevalence of the major eye and ha...

journal_title：Acta dermato-venereologica

authors： Lock-Andersen J,Wulf HC,Knudstorp ND

更新日期：1998-05-01 00:00:00