In vitro evidence supporting two mechanisms of action for the anion transport inhibitor L-644,711 in cerebral ischaemia.

abstract：:The association between glucocerebrosidase (GBA) mutations and Parkinson's disease (PD) is attracting increased attention worldwide. Results from previous studies on the association of GBA mutations with PD in different ethnicities remain contradictory. In order to derive a more comprehensive understanding of the rela...

journal_title：Neurological research

authors： Mao X,Wang T,Peng R,Chang X,Li N,Gu Y,Zhao D,Liao Q,Liu M

更新日期：2013-10-01 00:00:00

abstract：:This paper presents the results of transsphenoidal surgery in 41 consecutive patients with visual loss from pituitary adenomas. The most common pattern of loss was bitemporal hemianopia. Transsphenoidal decompression resulted in visual improvement in 78% of patients. If patients with optic atrophy and pre-operative co...

journal_title：Neurological research

authors： el-Azouzi M,Black PM,Candia G,Zervas NT,Panagopoulos KP

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:Leptin may be associated with cardiovascular disease. We tested to determine whether leptin is a marker for first-ever acute ischemic stroke (AIS) in a nested case-referent study. METHODS:Consecutive patients with first-ever AIS from May 2017 to December 2017 were included. Referents were matched for sex, ag...

journal_title：Neurological research

authors： Liu G,Dong M,Ma S,Fu L,Xiao Y,Zhong L,Geng J

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:The actual relationship between neural stem cells and SDF-1alpha/CXCR4 after brain injury has not yet been elucidated, although recent studies have speculated that stromal cell-derived factor-1alpha (SDF-1alpha) and its receptor, CXCR4, could contribute to neural stem cells migration after brain injury. In th...

journal_title：Neurological research

authors： Itoh T,Satou T,Ishida H,Nishida S,Tsubaki M,Hashimoto S,Ito H

更新日期：2009-02-01 00:00:00

abstract：:[15O]-water PET was performed on 12 patients with structural lesions for localization of the motor (n = 5), language (receptive and expressive; n = 6), and visual cortex (n = 1). All these patients underwent interactive image-guided surgery using an infrared digitizer and intraoperative electrical stimulation mapping ...

journal_title：Neurological research

authors： Viñas FC,Zamorano L,Mueller RA,Jiang Z,Chugani H,Fuerst D,Muzik O,Mangner TJ,Diaz FG

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:We evaluate the bladder volume and pressure through recording the bladder afferent activity in the sacral nerve roots in acute experiments of paraplegic dogs. These measurements are intended to report the status of the bladder and to adjust the stimulation parameters of an implantable electric stimulator. ME...

journal_title：Neurological research

authors： Saleh A,Sawan M,Elzayat EA,Corcos J,Elhilali MM

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Recurrent lumbar disc herniation (rLDH) is a common issue after primary discectomy and can cause severe pain, morbidity, and reoperation. The purpose of this systematic review was to evaluate the surgical management of recurrent lumbar disc herniation. METHODS:A systematic literature search was conducted usi...

journal_title：Neurological research

authors： Arif S,Brady Z,Enchev Y,Peev N

更新日期：2020-12-01 00:00:00

abstract：:The abnormal muscle response, elicited by electrical stimulation of one branch of the facial nerve and recorded from muscles innervated by another branch, has been used previously as an objective sign of hemifacial spasm in the development of animal models of this disorder. In the present study we recorded spontaneous...

journal_title：Neurological research

authors： Kuroki A,Møller AR

更新日期：1994-08-01 00:00:00

abstract：:Recent studies suggest that high plasma levels of tissue-type plasminogen activator (tPA) and its inhibitor (plasminogen activator inhibitor-1, PAI-1) are markers of an increased risk of atherothrombotic ischemic events such as stroke and myocardial infarction. In this prospective study, we measured tPA antigen, PAI-1...

journal_title：Neurological research

authors： Zunker P,Schick A,Padró T,Kienast J,Phillips A,Ringelstein EB

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVES:Equestrian sports can result in a variety of injuries to the nervous system due to many factors. We describe our series of 80 patients with injuries sustained during participation in equestrian sports. METHODS AND RESULTS:All patients seen at the regional trauma center with injuries associated with equestri...

journal_title：Neurological research

authors： Srinivasan V,Pierre C,Plog B,Srinivasan K,Petraglia AL,Huang JH

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Intracranial artery stenosis may be the most frequent cause of ischemic stroke in the world. Early detection of asymptomatic intracranial artery stenosis may allow for therapeutic intervention. Most elements of the Framingham stroke risk profile (FSRP) are also risk factors for intracranial artery stenosis....

journal_title：Neurological research

authors： Zhang Y,Wu S,Jia Z,Zhou Y,Liu X,Wang W,Wang T,Wang L,Zhang S,Jin C,Zhao X

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:To explore clinical features and compare of the difference between conservative treatment and surgical treatmentin prognosis of intracranial aneurysms associated with moyamoya disease (MMD). METHODS:104 patients with MMD a ssociated with intracranial aneurysms diagnosed by digital subtraction angiography (D...

journal_title：Neurological research

authors： Yan J,Lv M,Zeng E,Tang B,Xie S,Hong T

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Tadalafil is a selective phosphodiesterase type 5 (PDE-5) inhibitor approved for the treatment of erectile dysfunction. Less is known about the electroencephalography (EEG) effects of PDE-5 inhibitors, and the present study, therefore, examined the risk of EEG abnormalities associated with tadalafil. METHOD:...

journal_title：Neurological research

authors： Okuyucu EE,Guven O,Duman T,Gorur S,Melek IM,Akcin S,Yilmazer S

更新日期：2009-04-01 00:00:00

abstract：:The successful treatment of an intracranial arteriovenous malformation poses both technical and conceptual problems to the neurosurgeon. Treatment decisions are made in light of current understanding of the natural history of these lesions. It is important to understand the pros, cons and current indication of open cr...

journal_title：Neurological research

authors： Surdell DL Jr,Bhattacharjee S,Loftus CM

更新日期：2002-06-01 00:00:00

abstract：:The treatment of arteriovenous malformations depends on the efforts of a multidisciplinary team whose ultimate goal is to achieve better results when compared to the natural history of the pathology. The role of adjuvant treatment modalities such as radiosurgery and endovascular embolization is discussed. Treatment st...

journal_title：Neurological research

authors： de Oliveira E,Tedeschi H,Raso J

更新日期：1998-12-01 00:00:00

abstract：:Regional glucose utilization was measured in the rat brain after occlusion of the middle cerebral artery. Normoglycaemic rat had increased glucose use in the cerebral cortex adjacent to the infarct. A fraction of the nerve cells were irreversibly injured in this region. In hyperglycaemic rats, the glucose metabolism r...

journal_title：Neurological research

authors： Nedergaard M,Gjedde A,Diemer NH

更新日期：1987-12-01 00:00:00

abstract：:The survival of a group of patients with malignant gliomas of the brain submitted to radical surgery and radiotherapy was studied. The average survival was nearly 4 times longer with X-ray treatment than with cobalt 60 irradiation when a comparison was made between 24 patients with glioblasto-astroblastoma (grade 3-4)...

journal_title：Neurological research

authors： Christensen JC

更新日期：1987-09-01 00:00:00

abstract：:Dementia is one of the commonest neurological disorders in the elderly population. In regards to the increasing longevity of populations worldwide, prevention of dementia has become a major public health challenge. There has been an intense research in the identification of modifiable risk factors for dementia. These ...

journal_title：Neurological research

authors： Bergmann C,Sano M

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Misery perfusion increases the risk of stroke recurrence in patients with symptomatic major cerebral artery occlusion. The ratio of brain perfusion contralateral-to-affected asymmetry in the cerebellar hemisphere to brain perfusion affected-to-contralateral asymmetry in the cerebral hemisphere ...

journal_title：Neurological research

authors： Nomura J,Ogasawara K,Saito H,Terasaki K,Matsumoto Y,Takahashi Y,Ogasawara Y,Saura H,Yoshida K,Sato Y,Kubo Y,Ogawa A

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:Cerebral hyperperfusion syndrome (HPS) is a potential complication of extracranial-intracranial (EC-IC) bypass for moyamoya disease; however, the pathological threshold of the early cerebral blood flow (CBF) increases after EC-IC bypass has yet to be determined. The purpose of this study is to evaluate the pr...

journal_title：Neurological research

authors： Fujimura M,Niizuma K,Endo H,Sato K,Inoue T,Shimizu H,Tominaga T

更新日期：2015-02-01 00:00:00

abstract：:Insertion of pedicle screws in the thoracolumbar spine can be challenging. Incorrect placement can lead to a failure of fusion or to significant neurologic morbidity. Recently, techniques utilizing intraoperative monitoring and stereotaxis have been developed to achieve proper screw placement. While these techniques m...

journal_title：Neurological research

authors： Frank EH,Chamberland DL

更新日期：1997-12-01 00:00:00

abstract：:The purpose of this study was to determine the efficacy of nicardipine prolonged-release implants for preventing vasospasm in a canine SAH model in a dose-escalating placebo-controlled blind fashion. Drug-release kinetics of copoly(lactic/glycolic acid) pellet containing nicardipine were evaluated in vitro. In vivo, 1...

journal_title：Neurological research

authors： Kawashima A,Kasuya H,Sasahara A,Miyajima M,Izawa M,Hori T

更新日期：2000-09-01 00:00:00

abstract：:The selection of drugs to prevent the development of pathology in cerebral infarction remains an important problem. For the selection of effective drugs from among a large number of possible candidates, widely-used test screening techniques are sufficient for obtaining a good understanding of candidate drug effects. T...

journal_title：Neurological research

authors： Imaizumi S,Suzuki J,Kinouchi H,Yoshimoto T

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system. A contribution from complement has long been suspected. We investigated the association of complement factor H (CFH) Tyr402 His gene polymorphism and serum level in Egyptian patients with MS to examine whet...

journal_title：Neurological research

authors： Abdel Rasol HA,Helmy H,Aziz MA

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema after experimentally induced traumatic brain injury are evaluated. ...

journal_title：Neurological research

authors： Imer M,Omay B,Uzunkol A,Erdem T,Sabanci PA,Karasu A,Albayrak SB,Sencer A,Hepgul K,Kaya M

更新日期：2009-11-01 00:00:00

abstract：:Using magnetic resonance imaging, we reviewed 141 infratentorial infarcts in 81 consecutive cases: 65 infarcts were seen in the paramedian pons, while 18 in the posterior inferior cerebellar artery (PICA) territory and 17 in the watershed area between PICA and superior cerebellar artery. No comparable sign or symptom ...

journal_title：Neurological research

authors： Yin WM,Nagata K,Satoh Y,Yokoyama E,Watahiki Y,Yuya H,Hirata Y,Ogawa T,Inugami A

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Giant and large intracranial aneurysms represent enormous therapeutic challenges for neurosurgeons as well as for endovascular therapists. Since they may involve entire vessels or be irregular in shape, the rate of complete obliteration with GDCs is low and the incidence of recanalization is very high. So th...

journal_title：Neurological research

authors： Yang X,Wu Z,Mu S,Li Y,Lv M

更新日期：2008-07-01 00:00:00

abstract：:Complete thrombosis followed by recanalization of giant aneurysms is an infrequent process that has been exceptionally mentioned in relation to nongiant saccular aneurysms. A 25-year-old male presented with a right temporal hematoma and associated subarachnoid hemorrhage. Cerebral angiography revealed a small blister-...

journal_title：Neurological research

authors： Cohen JE,Rajz G,Umansky F,Spektor S

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVES:The present study characterized glial cell injury provoked in adult rat chiasm within 24 hours after a single, high-dose irradiation of 20 Gy. METHODS:All chiasmal glial cells in a section were counted, and the percentage of TUNEL-positive glial cells exhibiting apoptotic morphology was defined as the apopt...

journal_title：Neurological research

authors： Nagayama K,Kurita H,Nakamura M,Kusuda J,Tonari A,Takayama M,Fujioka Y,Shiokawa Y

更新日期：2005-06-01 00:00:00

abstract：:One case of dural arteriovenous malformation in the base of the anterior cranial fossa is reported. It was discovered by means of a PW-Doppler examination of angular branch of the ophthalmic artery in a patient under observation for hypertrophy of a superficial temporal artery. The nidus was located in the region of t...

journal_title：Neurological research

authors： Fiori L,Parenti G,Puglioli M,Padolecchia R

更新日期：1995-06-01 00:00:00