Localization of a gene for the human low-voltage EEG on 20q and genetic heterogeneity.

Abstract:

:The localization of a gene responsible for a normal variant of the human electroencephalogram to the distal part of chromosome 20q is reported. A linkage analysis, including 17 families with 191 individuals, tested with 73 RFLPs and 22 blood and serological markers, was performed for the low-voltage electroencephalogram. This is a normal variant of the human electroencephalogram with an autosomal dominant mode of inheritance. The results present strong evidence for close linkage with the highly polymorphic marker CMM6 (D20S19) and for genetic heterogeneity.

journal_name

Genomics

journal_title

Genomics

authors

Steinlein O,Anokhin A,Yping M,Schalt E,Vogel F

doi

10.1016/0888-7543(92)90408-k

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

69-73

issue

1

eissn

0888-7543

issn

1089-8646

pii

0888-7543(92)90408-K

journal_volume

12

pub_type

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