Treatment of human cutaneous sporotrichosis with itraconazole.

Abstract:

:Eighteen adult white male patients with cutaneous sporotrichosis were treated with itraconazole following different daily dose schemes. Cure was obtained in all cases after periods of 15-75 days (median 44 days) with total doses between 3.1 and 14.8 g (median 8.4 g). No serious side effects were observed and no relapses occurred in the follow-up period of between 1 and 26 months (median 14.7). These results show that itraconazole represents a safe and effective drug for the treatment of sporotrichosis. Comparison with other studies leads us to consider a daily dose of 200 mg as the most appropriate. A concomitant warming of the affected limbs should be recommended.

journal_name

Mycoses

journal_title

Mycoses

authors

Conti Díaz IA,Civila E,Gezuele E,Lowinger M,Calegari L,Sanabria D,Fuentes L,Da Rosa D,Alzueta G

doi

10.1111/j.1439-0507.1992.tb00836.x

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

153-6

issue

5-6

eissn

0933-7407

issn

1439-0507

journal_volume

35

pub_type

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