Higher eucaryotic cdc25 proteins are structurally related to phosphoseryl/threonyl protein phosphatases.

abstract：BACKGROUND INFORMATION:During apoptosis, the first morphological change is a distinct cell shrinkage known as the AVD (apoptotic volume decrease). This event is driven by a loss of intracellular K(+), which creates an osmotic gradient, drawing water out of the cell through AQPs (aquaporins). Loss of water in balance wi...

journal_title：Biology of the cell

authors： Jablonski EM,Hughes FM Jr

更新日期：2006-01-01 00:00:00

abstract：:A central issue in the understanding of Marfan syndrome deals with the functional architecture of fibrillin-containing microfibrils. Fibrillin-rich microfibrils are long extracellular matrix fibrillar components exhibiting a 50 nm periodic beaded-structure with a width of around 20-25 nm after rotary shadowing and a 1...

journal_title：Biology of the cell

authors： Hanssen E,Franc S,Garrone R

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND INFORMATION:Claudin-1 (CLDN1) is a four-span transmembrane protein localised at cell-cell tight junctions (TJs), playing an important role in epithelial impermeability and tissue homoeostasis under physiological conditions. Moreover, CLDN1 expression is up-regulated in several cancers, and the level of CLDN1...

journal_title：Biology of the cell

authors： Clément CMH,Deffieu MS,Dorobantu CM,Baumert TF,Ayala-Nunez NV,Mély Y,Ronde P,Gaudin R

更新日期：2020-05-01 00:00:00

abstract：:The daily rhythm in the activity of arylalkylamine N-acetyltransferase (AA-NAT) controls the rhythm in melatonin synthesis in the pineal gland. In the rat, transcriptional regulatory mechanisms play a major role in determining the observed pattern of AA-NAT gene expression. Remarkably, high levels of AA-NAT transcript...

journal_title：Biology of the cell

authors： Baler R,Covington S,Klein DC

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND INFORMATION:The identification of a source of stem cells able to regenerate skeletal muscle was the goal of numerous studies with the aim to develop new therapeutic approaches for genetic muscle diseases or muscle injuries. A series of studies have demonstrated that stem cells derived from various tissues ma...

journal_title：Biology of the cell

authors： Dimicoli-Salazar S,Bulle F,Yacia A,Massé JM,Fichelson S,Vigon I

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND INFORMATION:The ribonucleases (RNases) constitute a heterogeneous group of enzymes, which exert diverse and specific biological functions. Several RNases have been shown to control gene expression and cell differentiation. RNASET2, a novel member of the Rh/T2/S family of RNases, exerts micro-environmental co...

journal_title：Biology of the cell

authors： Vidalino L,Monti L,Haase A,Moro A,Acquati F,Taramelli R,Macchi P

更新日期：2012-01-01 00:00:00

abstract：:The pH-related change in morphology of vinblastine (VLB)-induced paracrystals formed in Chinese hamster ovary (CHO) cells was examined immunohistochemically in order to determine both the mechanism of tubulin crystallization and the influence of acidic pHs on cytoskeletal microtubules. Lowering the extracellular pH (p...

journal_title：Biology of the cell

authors： Takanari H,Morita J,Yamanaka H,Yada K,Takahashi A,Izutsu K

更新日期：1994-01-01 00:00:00

abstract：:Actin- and microtubule-based motors can propel different cargos along filaments. Within cells, they control the distribution of membrane-bound compartments by performing complementary tasks. Organelles make long journeys along microtubules, with class V myosins ensuring their capture and their dispersal in actin-rich ...

journal_title：Biology of the cell

authors： Desnos C,Huet S,Darchen F

更新日期：2007-08-01 00:00:00

abstract：:We took advantage of one of the main possibilities of ion microscopy, ie isotopic analysis, to study the cellular distribution of molecules labelled either with carbon 14 or with stable isotopes of low natural abundance such as nitrogen 15 and deuterium. The surface of the sample is bombarded with an ion beam (O2+, Cs...

journal_title：Biology of the cell

authors： Hindie E,Coulomb B,Beaupain R,Galle P

更新日期：1992-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) encodes two envelope glycoproteins, E1 and E2, that are released from HCV polyprotein by signal peptidase cleavage. These proteins assemble as a noncovalent heterodimer that is retained in the endoplasmic reticulum. The transmembrane domains of E1 and E2 are multifunctional and play a major rol...

journal_title：Biology of the cell

authors： Voisset C,Dubuisson J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND INFORMATION:Carcinoma of the oesophagus is the sixth leading cause of cancer death in the western world and is associated with a 5-year survival of less than 15%. Recent evidence suggests that stromal-epithelial interactions are fundamental in carcinogenesis. The advent of co-culture techniques permits the i...

journal_title：Biology of the cell

authors： Underwood TJ,Derouet MF,White MJ,Noble F,Moutasim KA,Smith E,Drew PA,Thomas GJ,Primrose JN,Blaydes JP

更新日期：2010-12-01 00:00:00

abstract：:The first step of polyamine uptake is the binding of polyamines to the cell membrane. In order to characterize the specificity of the putrescine binding sites at the surface of the glioblastoma cells (U251), we have carried out competition experiments between putrescine bound to latex microspheres and vizualized by sc...

journal_title：Biology of the cell

authors： Quemener V,Moulinoux JP,Khan NA,Seiler N

更新日期：1990-01-01 00:00:00

abstract：:The internalization of the yolk proteins has been investigated by electron microscopy and cytochemistry in the oocyte of the trout which stores up large quantities of yolk. The oocyte evolution has been followed for 18 months in a homogeneous group of animals. Anionic ferritin has been injected during vitellogenesis. ...

journal_title：Biology of the cell

authors： Busson-Mabillot S

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND INFORMATION:The mitogen-inducible gene-6 (Mig-6) is a non-kinase scaffolding adaptor protein. It has been shown that Mig-6 may play important roles in regulating stress response, maintaining homeostasis and functioning as a tumour suppressor. In this study, we investigated the role of Mig-6 in cellular senes...

journal_title：Biology of the cell

authors： Xie B,Zhao L,Chen H,Jin B,Mao Z,Yao Z

更新日期：2013-10-01 00:00:00

abstract：:Previous experiments have revealed a relatively weak electrostatic binding capacity of in vitro reconstituted intermediate filaments (IFs) as well as of natural IFs of whole cell mount preparations for purified ribosomal particles of mammalian origin. In order to demonstrate that such associations also occur in vivo, ...

journal_title：Biology of the cell

authors： Traub P,Bauer C,Hartig R,Grüb S,Stahl J

更新日期：1998-07-01 00:00:00

abstract：:Immunofluorescent techniques have been used in the analysis of DNA-RNA hybrids occurrence and its relationship to transcriptional events on polytene chromosomes of Drosophila subobscura. We have studied the distribution of these hybrids on uninduced/induced chromosomes. Two different indirect immunofluorescence method...

journal_title：Biology of the cell

authors： Arbona M,Cuenca JB,de Frutos R

更新日期：1992-01-01 00:00:00

abstract：:This study was undertaken to evaluate whether hypertrophy and hyperplasia of the pancreatic acinar cells induced by caerulein remained after termination of the hormonal treatment. Rats received subcutaneous injections of saline or caerulein for 4 days and were killed immediately after termination of treatment or 2, 15...

journal_title：Biology of the cell

authors： Morisset J,Grondin G

更新日期：1989-01-01 00:00:00

abstract：:ESCRTs (endosomal sorting complexes required for transport) were first discovered in yeast and are known to be required in the biogenesis of the MVB (multivesicular body). Most ESCRT research has been carried out in vitro using models such as yeast and mammalian cells in culture. The role of the ESCRTs genes in endoso...

journal_title：Biology of the cell

authors： Michelet X,Djeddi A,Legouis R

更新日期：2010-01-13 00:00:00

abstract：:Cell polarity is a fundamental property of cells from unicellular to multicellular organisms. Most of the time, it is essential so that the cells can achieve their function. The fission yeast Schizosaccharomyces pombe is a powerful genetic model organism for studying the molecular mechanisms of the cell polarity proce...

journal_title：Biology of the cell

authors： La Carbona S,Le Goff C,Le Goff X

更新日期：2006-11-01 00:00:00

abstract：:Peroxisomes are present in most eukaryotic cell types, and have different enzymatic content and metabolic functions throughout the life scale. The endosymbiotic origin of these DNA-devoid organelles is supported by evolutionary data concerning genes encoding not only most peroxisomal proteins, but also several transcr...

journal_title：Biology of the cell

authors： Latruffe N,Vamecq J

更新日期：2000-09-01 00:00:00

abstract：:Arabinoxylans were localised by immunocytochemistry using polyclonal antibodies in the cell walls of the apical internode of maize after degradation in the rumen. In order to understand the significance of arabinoxylan in digestibility property, two lines of maize differing in digestibility were used. Wide variations ...

journal_title：Biology of the cell

authors： Migné C,Prensier G,Cornu A,Grenet E

更新日期：1996-01-01 00:00:00

abstract：:The highly conserved VICKZ (Vg1 RBP/Vera, IMP-1,2,3, CRD-BP, KOC, ZBP-1) family of RNA-binding proteins recognize specific cis-acting elements in a variety of different RNAs and have been implicated in cell polarity and migration, cell proliferation, and cancer. In just the last two years, the use of transgenic mice, ...

journal_title：Biology of the cell

authors： Yisraeli JK

更新日期：2005-01-01 00:00:00

abstract：:Immunogold labeling and biochemical methods were used to localize the site of viral protein synthesis in frog virus 3 (FV3)-infected baby hamster kidney (BHK) cells. Immunogold labeling studies of Triton-extracted (cytoskeletons), FV3-infected BHK cells with antivimentin antibodies showed that the major components of ...

journal_title：Biology of the cell

authors： Murti K,Goorha R

更新日期：1989-01-01 00:00:00

abstract：:Although there are many macromolecular complexes which play extremely important roles in biology, and despite continued progress in X-ray crystallographic and NMR methods, it is still very difficult to obtain atomic level structural information about such large assemblies. It is now clear that a powerful approach is t...

journal_title：Biology of the cell

authors： Wade RH,Hewat EA

更新日期：1994-01-01 00:00:00

abstract：:In 2001, with-no-lysine (WNK) kinases were identified as the genes responsible for the human hereditary hypertensive disease pseudohypoaldosteronism type II (PHAII). It took a further 6 years to clarify that WNK kinases participate in a signaling cascade with oxidative stress-responsive gene 1 (OSR1), Ste20-related pr...

journal_title：Biology of the cell

authors： Uchida S,Sohara E,Rai T,Sasaki S

更新日期：2014-02-01 00:00:00

abstract：:The influence of triiodothyronine (T3) on avian myoblast proliferation and differentiation was studied in secondary cultures using plating densities of 2,500 and 7,000 cells/cm2. Culture media were depleted of T3 (control myoblasts) and increasing amounts were then added to concentrations of 0.6, 3 and 15 nM T3 (treat...

journal_title：Biology of the cell

authors： Marchal S,Cassar-Malek I,Pons F,Wrutniak C,Cabello G

更新日期：1993-01-01 00:00:00

abstract：:Circulating glucocorticoid (GC) levels are thought to modulate the basal activity of pro-opiomelanocortin (POMC) neurons within the mediobasal hypothalamus (MBH) of the male rat. In a recent study we demonstrated that Fos-immunoreactivity (Fos-IR) was spontaneously induced throughout the dark phase of the light/dark c...

journal_title：Biology of the cell

authors： Jamali KA,Tramu G

更新日期：1997-12-01 00:00:00

abstract：:Interactions of cells with the extracellular matrix are essential for the control of tissue remodelling, cell migration, and embryogenesis. At the cell-extracellular matrix contact points, specialized structures are formed and termed focal adhesions, where transmembrane adhesion receptors provide a structural link bet...

journal_title：Biology of the cell

authors： Petit V,Thiery JP

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND INFORMATION:Caspases are cysteine proteases that mediate apoptosis (programmed cell death) initiation and execution. Apoptosis is a conserved mechanism shared by all metazoans, although its physiological function and complexity show considerable taxon-dependent variations. To gain insight into the caspase re...

journal_title：Biology of the cell

authors： Weill M,Philips A,Chourrout D,Fort P

更新日期：2005-11-01 00:00:00

abstract：:Previous studies suggest that oligodeoxynucleotide (ODN) cellular uptake is cell cycle-dependent which may have important implications in cancer cell targeting. To further our understanding of ODN transport and activity, this study examines the relationships between the cell cycle, ODN cellular uptake, intracellular t...

journal_title：Biology of the cell

authors： Wu-Pong S,Bard J,Huffman J,Jimerson J

更新日期：1997-07-01 00:00:00