Pyrrolo[2,3-h]quinolinones: synthesis and photochemotherapic activity.

Abstract:

:A series of derivatives of the new ring system pyrrolo[2,3-h]quinoline-2-one was synthesized and evaluated as photoreagents toward cultured human tumor cells. Remarkable phototoxycity resulted for some derivatives, especially those bearing the phenyl group at the 7-position.

journal_name

Bioorg Med Chem Lett

authors

Barraja P,Diana P,Lauria A,Montalbano A,Almerico AM,Dattolo G,Cirrincione G,Viola G,Dall'Acqua F

doi

10.1016/s0960-894x(03)00529-8

subject

Has Abstract

pub_date

2003-08-18 00:00:00

pages

2809-11

issue

16

eissn

0960-894X

issn

1464-3405

pii

S0960894X03005298

journal_volume

13

pub_type

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