Yeast RNA helicases of the DEAD-box family involved in translation initiation.

abstract：BACKGROUND INFORMATION:MTA1 (metastasis-associated gene 1) has been reported to be overexpressed in cancers with high potential to metastasize. Studies of the molecular mechanisms revealed that MTA1 plays an important role in the process of metastasis of many types of cancer. However, the role of MTA1 in melanoma devel...

journal_title：Biology of the cell

authors： Qian H,Yu J,Li Y,Wang H,Song C,Zhang X,Liang X,Fu M,Lin C

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND INFORMATION:The transcription factor NFAT (nuclear factor of activated T-cell) family comprises important regulators in immuno-responses and mouse embryonic development, including early cardiovascular and heart valve development. The mechanism involved, however, is not fully understood. Nkx2-5 (NK2 transcrip...

journal_title：Biology of the cell

authors： Chen Y,Cao X

更新日期：2009-06-01 00:00:00

abstract：:Immunogold labeling and biochemical methods were used to localize the site of viral protein synthesis in frog virus 3 (FV3)-infected baby hamster kidney (BHK) cells. Immunogold labeling studies of Triton-extracted (cytoskeletons), FV3-infected BHK cells with antivimentin antibodies showed that the major components of ...

journal_title：Biology of the cell

authors： Murti K,Goorha R

更新日期：1989-01-01 00:00:00

abstract：:Flow DNA analysis was performed on samples from 71 surgically removed lung cancers and from 145 patients undergoing bronchoscopy. Abnormal DNA stem lines, characterized by their DNA index (DI), were frequently observed in operated lung carcinomas (87%). Two or three abnormal DNA stem lines were discovered simultaneous...

journal_title：Biology of the cell

authors： Chassevent A,Berruchon J,Bertrand G,Chretien MF,Tuchais C,George P,Larra F,Rebel A,Oury M

更新日期：1986-01-01 00:00:00

abstract：:Several transformed cells have been demonstrated to secrete growth factors. We studied the effect of conditioned medium from neoplastic rat pleural mesothelial cells on normal and neoplastic mesothelial cell growth. The results showed that the concentrated conditioned medium stimulated neoplastic mesothelial cell grow...

journal_title：Biology of the cell

authors： Van der Meeren A,Levy F,Bignon J,Jaurand MC

更新日期：1988-01-01 00:00:00

abstract：:The dynamics of change in mitochondria-rich (MR) cells density in the skin epithelium of Bufo viridis was studied on skin biopsies taken in vivo, throughout experimental periods lasting up to 3 months. When the bathing solution contained Cl-, MR cells' density (Dmrc) greatly decreased. There was one exception, when th...

journal_title：Biology of the cell

authors： Katz U,Gabby S

更新日期：1995-01-01 00:00:00

abstract：:Flow cytometry has important advantages over conventional techniques. It is rapid, highly sensitive and allows multi-parametric analysis and cell sorting. Potential exists for the measurement of many cell functions by flow cytometry. The technique can be used to determine cell viability, intracellular calcium and pH, ...

journal_title：Biology of the cell

authors： Maftah A,Huet O,Gallet PF,Ratinaud MH

更新日期：1993-01-01 00:00:00

abstract：:PD (peritoneal dialysis) is an established mode of renal replacement therapy, based on the exchange of fluid and solutes between blood in peritoneal capillaries and a dialysate that has been introduced into the peritoneal cavity. The dialysis process involves diffusive and convective transports and osmosis through the...

journal_title：Biology of the cell

authors： Devuyst O,Ni J,Verbavatz JM

更新日期：2005-09-01 00:00:00

abstract：:Our knowledge of cell signalling pathways in the molluscan immune system and their response to immunological challenge is currently poor. The present study focused on the Protein Kinase C (PKC) pathway in the immune cells (haemocytes) of Lymnaea stagnalis and its response following exposure to bacterial lipopolysaccha...

journal_title：Biology of the cell

authors： Walker AJ,Plows LD

更新日期：2003-11-01 00:00:00

abstract：:Alpha 2-macroglobulin (alpha 2M) is a plasma inhibitor of proteinases, the steric mechanism of which is based on a considerable conformational change. The typical and distinct H-like shape of alpha 2M-chymotrypsin (alpha 2M-chy) complexes seen by electron microscopy led us to an ultrastructural study of the binding of...

journal_title：Biology of the cell

authors： Boisset N,Taveau JC,Barray M,Van Leuven F,Delain E,Lamy JN

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Loss of sensitivity to TGF-beta1 (transforming growth factor beta1)-induced growth arrest is an important step towards malignant transformation in human epithelial cells, and Id-1 (inhibitor of differentiation or DNA binding-1) has been associated with cell proliferation and cell-cycle progressio...

journal_title：Biology of the cell

authors： Di K,Ling MT,Tsao SW,Wong YC,Wang X

更新日期：2006-09-01 00:00:00

abstract：:Rotation-mediated aggregate cultures of foetal rat liver cells were prepared and grown in a chemically defined medium. Their capacity for cellular organisation and maturation was studied over a culture period of 3 wk by using both morphologic and biochemical criteria. It was found that within each aggregate, distinct ...

journal_title：Biology of the cell

authors： Guigoz Y,Werffeli P,Favre D,Juillerat M,Wellinger R,Honegger P

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Our previous studies have shown that calreticulin, a Ca2+-binding chaperone located in the endoplasmic reticulum, affects cell-substratum adhesions via the induction of vinculin and N-cadherin. Cells overexpressing calreticulin contain more vinculin than low expressers and make abundant contacts ...

journal_title：Biology of the cell

authors： Papp S,Fadel MP,Opas M

更新日期：2007-07-01 00:00:00

abstract：:One of the initial events required for the expression of cartilage-specific macromolecules in monolayer cultures is the reversion to the initial round shape of chondrocytes. Thus, considerable research efforts have focused on developing reliable procedures to maintain a round morphology of cultured chondrocytes. Our s...

journal_title：Biology of the cell

authors： Loty S,Forest N,Boulekbache H,Sautier JM

更新日期：1995-01-01 00:00:00

abstract：:Image analysis was used to study the repair process of a circular mechanical lesion of confluent human endothelial cells in culture after irradiation (10 Gy) prior to wounding. Coverage of denuded areas 48 and 96 h after injury of endothelial cells was identical in control and irradiated cultures, although the labelin...

journal_title：Biology of the cell

authors： Klein-Soyer C,Beretz A,Cazenave JP,Driot F,Maffrand JP

更新日期：1990-01-01 00:00:00

abstract：:In cold-stressed oocytes of Pleurodeles waltl, lampbrush chromosome lateral loops exhibited important structural modifications which were visualized under light microscopy. Electron microscopy study revealed that the RNP particles associated with growing transcripts in the matrix of these loops were 15 nm at 8 degrees...

journal_title：Biology of the cell

authors： N'Da E,Bonnanfant-Jais ML,Moreau N,Angelier N

更新日期：1990-01-01 00:00:00

abstract：:The location of lipopolysaccharide (LPS) was studied by immunofluorescence and immunoelectron microscopy in macrophages infected with a non-invasive Shigella dysenteriae 1 strain. Bacterial degradation began only 3 h after the end of infection. The first visible sign of degradation was detected by immunogold labelling...

journal_title：Biology of the cell

authors： Dacosta B,Ryter A,Mounier J,Sansonetti P

更新日期：1990-01-01 00:00:00

abstract：:This review highlights new developments in miRNA as diagnostic and surveillance tools in diseases damaging the renal proximal tubule mediated by endothelin in the field of renal carcinoma, proteinuric kidney disease and tubulotoxicity. A new mechanism in the miRNA regulation of proteins leads to the binding of the miR...

journal_title：Biology of the cell

authors： Fries JWU

更新日期：2019-07-01 00:00:00

abstract：:The pH-related change in morphology of vinblastine (VLB)-induced paracrystals formed in Chinese hamster ovary (CHO) cells was examined immunohistochemically in order to determine both the mechanism of tubulin crystallization and the influence of acidic pHs on cytoskeletal microtubules. Lowering the extracellular pH (p...

journal_title：Biology of the cell

authors： Takanari H,Morita J,Yamanaka H,Yada K,Takahashi A,Izutsu K

更新日期：1994-01-01 00:00:00

abstract：:Netrins are secreted proteins that play a crucial role in neuronal migration and in axon guidance during the development of the nervous system. Netrin-1 has been shown to interact with the transmembrane receptors DCC and UNC5H and these receptors appeared of key importance in mediating the chemotropic activity of netr...

journal_title：Biology of the cell

authors： Mehlen P,Mazelin L

更新日期：2003-10-01 00:00:00

abstract：:Genome replication and assembly of viruses often takes place in specific intracellular compartments where viral components concentrate, thereby increasing the efficiency of the processes. For a number of viruses the formation of 'factories' has been described, which consist of perinuclear or cytoplasmic foci that most...

journal_title：Biology of the cell

authors： Novoa RR,Calderita G,Arranz R,Fontana J,Granzow H,Risco C

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND INFORMATION:CLEM (correlative live cell and electron microscopy) seeks to bridge the data acquired with different imaging strategies, typically between light microscopy and electron microscopy. It has been successfully applied in cell cultures, although its use in multicellular systems is hampered by difficu...

journal_title：Biology of the cell

authors： Kolotuev I,Schwab Y,Labouesse M

更新日期：2009-12-04 00:00:00

abstract：:Bistramide A, a new toxin isolated from a New Caledonian Urochordata, shows an antiproliferative effect on a non-small-cell lung carcinoma line in vitro and G1-blockade. In this work, the growth arrest induced by bistramide A was shown to be irreversible as assessed by growth kinetics of pretreated cells. Furthermore,...

journal_title：Biology of the cell

authors： Riou D,Roussakis C,Robillard N,Biard JF,Verbist JF

更新日期：1993-01-01 00:00:00

abstract：:We took advantage of one of the main possibilities of ion microscopy, ie isotopic analysis, to study the cellular distribution of molecules labelled either with carbon 14 or with stable isotopes of low natural abundance such as nitrogen 15 and deuterium. The surface of the sample is bombarded with an ion beam (O2+, Cs...

journal_title：Biology of the cell

authors： Hindie E,Coulomb B,Beaupain R,Galle P

更新日期：1992-01-01 00:00:00

abstract：:An interaction between human poly(A)-binding protein (PABP) et human eRF3 has been demonstrated using a double-hybrid approach and in vitro assays. Here, we show that the binding of both proteins is conserved through evolution. We also demonstrate that the last 39 C-terminal amino acids of PABP contain the interface t...

journal_title：Biology of the cell

authors： Cosson B,Berkova N,Couturier A,Chabelskaya S,Philippe M,Zhouravleva G

更新日期：2002-09-01 00:00:00

abstract：:A quantitative ultrastructural study was performed on 56 ejaculates showing anomalies of the sperm axonemal complex. The anomalies comprised either the absence of one, or more often several, axonemal structures, or defective elongation of the doublets. Several characteristics relating to the extent and superimposition...

journal_title：Biology of the cell

authors： Escalier D,David G

更新日期：1984-01-01 00:00:00

abstract：:This study was undertaken to evaluate the effects of caerulein, a CCK analog, on the different cell populations of the pancreatic tissue and their respective turnover. Rats received saline or caerulein subcutaneously and 3H-thymidine intraperitoneally three times a day for 4 days. They were sacrificed immediately afte...

journal_title：Biology of the cell

authors： Morisset J,Grondin G

更新日期：1989-01-01 00:00:00

abstract：:Bovine tracheal gland (BTG) cells in culture show an epithelial-fibroblastoid transition after several passages. To investigate these BTG cell phenotype changes, we studied the effects of both the culture medium and passage number on the expression of epithelial cytoskeletal proteins and glandular serous cell markers....

journal_title：Biology of the cell

authors： Benali R,Dupuit F,Chevillard M,Jacquot J,Haye B,Puchelle E

更新日期：1991-01-01 00:00:00

abstract：:Although there are many macromolecular complexes which play extremely important roles in biology, and despite continued progress in X-ray crystallographic and NMR methods, it is still very difficult to obtain atomic level structural information about such large assemblies. It is now clear that a powerful approach is t...

journal_title：Biology of the cell

authors： Wade RH,Hewat EA

更新日期：1994-01-01 00:00:00

abstract：:Flow cytometry (FCM) analysis of cellular DNA content has become an increasingly important clinical research tool for the measurement and identification of abnormal cell populations. Examination of cellular DNA content can provide information for use in cell cycle analysis in cancer studies. Most researchers would agr...

journal_title：Biology of the cell

authors： Spyratos F

更新日期：1993-01-01 00:00:00