Exotic and emerging viral encephalitides.

abstract：PURPOSE OF REVIEW:Experimental and clinical studies have suggested that epileptic seizures can be modulated or interrupted by electrical stimulations of subcortical structures that may exert a remote control on seizure generators. The aim of this review is to present these recent reports and to address the perspectives...

journal_title：Current opinion in neurology

authors： Kahane P,Depaulis A

更新日期：2010-04-01 00:00:00

abstract：:The pathogenesis of primary vasculitides, which are assumed to have an autoimmune pathogenesis, is not well understood. The endothelial cell adhesion molecules seem to play an active role, which varies according to the histopathologic stage of vascular lesions. The role of genetic factors also seems quite important, a...

journal_title：Current opinion in neurology

authors： Said G

更新日期：1999-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Research on the pathophysiology of syndromic autism spectrum disorder (ASD) has contributed to the uncovering of mechanisms in nonsyndromic ASD. The current review aims to compare recent progress in therapeutics development for ASD with those for fragile X syndrome (FXS), the most frequent monogenic f...

journal_title：Current opinion in neurology

authors： Yamasue H,Aran A,Berry-Kravis E

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Tension-type headache is the most common type of headache and, in its chronic form, one of the most neglected and difficult types of headache to treat. Recently published data will be reviewed. RECENT FINDINGS:The prevalence of frequent tension-type headache increased significantly from 1989 to 2001,...

journal_title：Current opinion in neurology

authors： Bendtsen L,Jensen R

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The relative influence of genes and environment on the liability to neurodevelopmental disorders (NDDs) can be investigated using a twin design. This review highlights the results of the most recent twin studies of NDDs. RECENT FINDINGS:Recent twin studies have confirmed that NDDs show moderate-to-hi...

journal_title：Current opinion in neurology

authors： Posthuma D,Polderman TJ

更新日期：2013-04-01 00:00:00

abstract：:A long series of studies beginning with the pioneering experiments of Wiesel and Hubel [1] has shown that correct visual experience is crucial for the development of the visual system. Recent results suggest that neurotrophic factors of the nerve growth factor family might have a relevant role in mediating the effects...

journal_title：Current opinion in neurology

authors： Pizzorusso T,Maffei L

更新日期：1996-04-01 00:00:00

abstract：:This article reviews the current knowledge with regard to neurotoxicity of conventional radiation, including recent understanding of the pathophysiology, molecular biology, diagnostic evaluation and clinical presentations, as well as proposed treatment modalities and possible protective agents. ...

journal_title：Current opinion in neurology

authors： New P

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Migraine has traditionally been categorized as a pain disorder, focusing on headache as its central feature. This narrow view does not account for the complex array of premonitory and postrdromal symptoms that occur in the hours before and after headache. This review outlines evidence that supports a ...

journal_title：Current opinion in neurology

authors： Charles A

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Inflammation is implicated in ischaemic stroke as a general cardiovascular risk factor, a possible immediate trigger, a component (and possible exacerbating factor) of the response to tissue injury, a marker of future risk, and as a therapeutic target. Each aspect is reviewed. RECENT FINDINGS:Evidenc...

journal_title：Current opinion in neurology

authors： Muir KW,Tyrrell P,Sattar N,Warburton E

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review considers the role of neuroimaging in developmental disorders by highlighting recent studies in two distinct, but overlapping, developmental disorders: autism and fragile X syndrome. RECENT FINDINGS:After a decade of conflicting results in neuroimaging studies of autism, recent studies ha...

journal_title：Current opinion in neurology

authors： Greicius MD

更新日期：2003-04-01 00:00:00

abstract：:Trauma to the developing brain constitutes an unexplored field. The few studies attempting to model and study paediatric head trauma, the leading cause of death and disability in the paediatric population, have revealed interesting aspects and potential targets for future research. One feature unique to the developing...

journal_title：Current opinion in neurology

authors： Felderhoff-Mueser U,Ikonomidou C

更新日期：2000-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to systematically and critically review the relationship between migraine and estrogen, the predominant female sex hormone, with a focus on studies published in the last 18 months. RECENT FINDINGS:Recent functional MRI (fMRI) studies of the brain support the existence of anatomical and fun...

journal_title：Current opinion in neurology

authors： Chai NC,Peterlin BL,Calhoun AH

更新日期：2014-06-01 00:00:00

abstract：:Central nervous system infections are an important cause of childhood morbidity and mortality. This review discusses recent developments in diagnostic tests, management strategies, and prevention of bacterial and tubercular meningitis. ...

journal_title：Current opinion in neurology

authors： Singhi PD,Singhi SC

更新日期：1995-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The search for a cure for Duchenne muscular dystrophy and other muscular dystrophies is progressing rapidly despite significant challenges posed by some genes and the complexity of targeting all skeletal muscles. This review focuses on three areas in which experimental clinical studies are in progress...

journal_title：Current opinion in neurology

authors： Muntoni F,Wells D

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The advent of novel techniques for tracing connections in vivo, such as diffusion tensor magnetic resonance imaging tractography, allows us, for the first time in the human brain, to study the microstructural integrity of white matter fibres and perform virtual dissections of large scale neurocognitiv...

journal_title：Current opinion in neurology

authors： Catani M

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses recent studies on myasthenia gravis with onset in childhood (juvenile myasthenia gravis) and neonatal myasthenia gravis. RECENT FINDINGS:The occurrence of myasthenia gravis in childhood is strongly influenced by genetic and environmental factors. Juvenile myasthenia gravis is as...

journal_title：Current opinion in neurology

authors： Evoli A

更新日期：2010-10-01 00:00:00

abstract：:Although spreading depression has been known for over 50 years, recent research into this interesting experimental phenomenon provides evidence for an integrative role of spreading depression in brain pathophysiology. Spreading depression activates neurophysiological pathways that may have widespread consequences on b...

journal_title：Current opinion in neurology

authors： Parsons AA

更新日期：1998-06-01 00:00:00

abstract：:Recent positron emission tomography investigations found spreading oligemia in the early phases of a human migraine attack. During the headache phase, increased cerebral blood flow was found in cortical sensory association areas and unilaterally in the brainstem. The brainstem activation persisted after complete relie...

journal_title：Current opinion in neurology

authors： Diener HC,May A

更新日期：1996-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In recent years, advances in the understanding of the regulatory mechanisms of the immune system has led to the development of new approaches for cancer treatment. Currently, immune checkpoint inhibitors are the first successful examples of this approach and several agents that target cytotoxic lympho...

journal_title：Current opinion in neurology

authors： Hottinger AF

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent years have witnessed the discoveries of several genes causing neurodegeneration with brain iron accumulation (NBIA) and subsequently their novel classification scheme was suggested. The first results of treatments with modern chelating drugs are also being published. RECENT FINDINGS:Most recen...

journal_title：Current opinion in neurology

authors： Dusek P,Schneider SA

更新日期：2012-08-01 00:00:00

abstract：:Although theoretical reasons exist for believing that selegiline slows the progression of Parkinson's disease, this has not been shown in clinical trials. Selegiline improves the symptoms of Parkinson's disease, allowing the introduction of levodopa to be delayed in de-novo patients and, later, for levodopa to be used...

journal_title：Current opinion in neurology

authors： Hely MA,Morris JG

更新日期：1996-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to review sleep disturbances in different movement disorders, mainly Parkinson's disease, and highlight current concepts on merging the boundaries between movement disorders and dissociative states of being. RECENT FINDINGS:Since the observation that rapid eye movement sleep behavior disor...

journal_title：Current opinion in neurology

authors： Giannoccaro MP,Antelmi E,Plazzi G

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the pathogenesis, clinical presentation, course, and therapy of herpes simplex encephalitis (HSE), the most fatal viral encephalitis, in which prognosis is dependent on early diagnosis and effective therapy. RECENT FINDINGS:Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) ...

journal_title：Current opinion in neurology

authors： Steiner I

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The results of phase 2 randomized controlled trials for the prevention of episodic and chronic migraine demonstrating the efficacy and safety of four mAbs targeting the calcitonin gene-related peptide (CGRP) pathway [ALD403 (eptinezumab), AMG334 (erenumab), LY2951742 (galcanezumab) and TEV48125 (frema...

journal_title：Current opinion in neurology

authors： Mitsikostas DD,Reuter U

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Although cluster headache has traditionally been thought of as a vascular headache disorder, its periodicity suggests an involvement of central areas such as the hypothalamus. This review covers the past 3 years, which have seen remarkable progress in understanding the pathophysiology of circadian hea...

journal_title：Current opinion in neurology

authors： May A,Leone M

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Left visual neglect is a frequent and dramatic consequence of right hemisphere lesions. Diagnosis is important because behavioural and pharmacological treatments are available. Furthermore, neglect raises important issues concerning the brain mechanisms of consciousness, perception and attention. REC...

journal_title：Current opinion in neurology

authors： Bartolomeo P

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The successful motor rehabilitation of stroke, traumatic brain-injured and spinal cord-injured patients requires an intensive and task-specific therapy approach. Budget constraints limit a hand-to-hand therapy approach, so that intelligent machines may offer a solution to promote motor recovery and ob...

journal_title：Current opinion in neurology

authors： Hesse S,Schmidt H,Werner C,Bardeleben A

更新日期：2003-12-01 00:00:00

abstract：:An increasing number of mutations in the CACNA1A gene have been identified, which are associated with a broad clinical spectrum, including familial hemiplegic migraine. Transfection studies and mouse model analyses are currently being undertaken to study the correlation between CACNA1A mutations and disease. ...

journal_title：Current opinion in neurology

authors： Kors EE,van den Maagdenberg AM,Plomp JJ,Frants RR,Ferrari MD

更新日期：2002-06-01 00:00:00

abstract：:The phakomatoses are a diverse group of diseases characterized by skin lesions in early childhood followed by the development of tumors in many other organs. Tuberous sclerosis complex and neurofibromatosis 1 are of special interest to the neurologist because of their prominent neuro-oncological and neuro-developmenta...

journal_title：Current opinion in neurology

authors： MacCollin M,Kwiatkowski D

更新日期：2001-04-01 00:00:00

abstract：:The population of pediatric patients with cerebrovascular disease presents a unique set of challenges to the neurosurgeon. The wide scope of pathology, including arteriovenous malformations, cavernous malformations and moyamoya disease, coupled with marked advances in diagnosis and treatment of these conditions over t...

journal_title：Current opinion in neurology

authors： Smith ER,Butler WE,Ogilvy CS

更新日期：2002-04-01 00:00:00