Circulating proangiogenic cytokines and angiogenesis inhibitor endostatin in untreated patients with chronic lymphocytic leukemia.

abstract：:Dengue is an acute febrile illness with a wide spectrum of signs and symptoms ranging from mild to severe forms characterized by plasma leakage that can be fatal. NK cells are one of the main effectors in early infection and may play an important role in dengue pathogenesis. We investigated NK cell involvement during ...

journal_title：Mediators of inflammation

authors： Gandini M,Petitinga-Paiva F,Marinho CF,Correa G,De Oliveira-Pinto LM,de Souza LJ,Cunha RV,Kubelka CF,de Azeredo EL

更新日期：2017-01-01 00:00:00

abstract：:It has been suggested that the supernatant of LPSstimulated macrophages (macrophage nociceptive factor, MNF) promotes nociception in mice. Intraperitoneal administration of MNF induced dose-related writhing, which reached a plateau between 18 and 26 min after injection and decreased within 60 min. The release of MNF w...

journal_title：Mediators of inflammation

authors： Thomazzi SM,Ribeiro RA,Campos DI,Cunha FQ,Ferreira SH

更新日期：1997-01-01 00:00:00

abstract：:The aim of this study was to evaluate the relationship between serum transforming growth factor β 1 (TGF- β 1) concentrations and the duration of type 1 diabetes mellitus (T1DM) in children and adolescents. One hundred and sixteen patients with T1DM and 19 healthy controls were examined. Serum TGF- β 1 concentrations ...

journal_title：Mediators of inflammation

authors： Zorena K,Raczyńska D,Wiśniewski P,Malinowska E,Myśliwiec M,Raczyńska K,Rachoń D

更新日期：2013-01-01 00:00:00

abstract：:We recently reported the immune-enhancing effects of a high-molecular-weight fraction (HMF) of CW in macrophages and immunosuppressed mice, and this effect was attributed to a crude polysaccharide. As polysaccharides may also have anti-inflammatory functions, we investigated the anti-inflammatory effects and related m...

journal_title：Mediators of inflammation

authors： Cho CW,Ahn S,Lim TG,Hong HD,Rhee YK,Yang DC,Jang M

更新日期：2017-01-01 00:00:00

abstract：:Hydroxysafflor yellow A (HSYA) is an effective therapeutic agent for inflammatory diseases and autoimmune disorders; however, its regulatory effect on NLRP3 inflammasome activation in macrophages has not been investigated. In this study, we predicted the potential interaction between HSYA and xanthine oxidase (XO) via...

journal_title：Mediators of inflammation

authors： Xu X,Guo Y,Zhao J,Wang N,Ding J,Liu Q

更新日期：2016-01-01 00:00:00

abstract：:Perinatal insults and subsequent neuroinflammation are the major mechanisms of neonatal brain injury, but there have been only scarce reports on the associations between hypoxic preconditioning and glial activation. Here we use neonatal hypoxia-ischemia brain injury model in 7-day-old rats and in vitro hypoxia model w...

journal_title：Mediators of inflammation

authors： Chen CY,Sun WZ,Kang KH,Chou HC,Tsao PN,Hsieh WS,Fu WM

更新日期：2015-01-01 00:00:00

abstract：:Statins exert pleiotropic effects on endothelial cells in addition to lowering cholesterol. 15-Lipoxygenase-1 (ALOX15) has been implicated in vascular inflammation and disease. The relationship between atorvastatin and ALOX15 was investigated using a rat carotid artery balloon-injury model. Hematoxylin and eosin (HE) ...

journal_title：Mediators of inflammation

authors： Zhang P,Xing X,Hu C,Yu H,Dong Q,Chang G,Qin S,Liu J,Zhang D

更新日期：2016-01-01 00:00:00

abstract：:The development of an acidic tissue environment is a hallmark of a variety of inflammatory processes and solid tumors. However, little attention has been paid so far to analyze the influence exerted by extracellular pH on the immune response. Tissue acidosis (pH 6.0 to 7.0) is usually associated with the course of inf...

journal_title：Mediators of inflammation

authors： Erra Díaz F,Dantas E,Geffner J

更新日期：2018-12-30 00:00:00

abstract：:Microparticles (MPs) are induced during apoptosis, cell activation, and even "spontaneous" release. Initially MPs were considered to be inert cellular products with no biological function. However, an extensive research and functional characterization have shown that the molecular composition and the effects of MPs de...

journal_title：Mediators of inflammation

authors： Burbano C,Rojas M,Vásquez G,Castaño D

更新日期：2015-01-01 00:00:00

abstract：:Inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, and leukotrienes, impact the immune system, usually as proinflammatory factors. Other mediators act as regulatory components to establish homeostasis after injury or prevent the inflammatory process. Histamine, a biogenic vasoactive am...

journal_title：Mediators of inflammation

authors： Branco ACCC,Yoshikawa FSY,Pietrobon AJ,Sato MN

更新日期：2018-08-27 00:00:00

abstract：:Non-cystic fibrosis-related bronchiectasis is a chronic inflammatory lung disease, which is regarded as an "orphan" lung disease, with little research devoted to the study of this condition. Bronchiectasis results in impaired quality of life and mortality if left untreated. The tools available in the armamentarium for...

journal_title：Mediators of inflammation

authors： Masekela R,Green RJ

更新日期：2012-01-01 00:00:00

abstract：:Little is known about the cause and pathophysiology of middermal elastolysis (MDE). In this condition, variable inflammatory infiltrate may be present or not together with loss of elastic fibres in the middermis that spares both papillary and lower reticular dermis. MDE may be a consequence of abnormal extracellular m...

journal_title：Mediators of inflammation

authors： De Cunto G,Lamberti A,de Santi MM,Miracco C,Fimiani M,Lungarella G,Cavarra E

更新日期：2017-01-01 00:00:00

abstract：Background:Gut microbiota is implied in obesity, because of its ability to harvest energy from diet, and in the regulation of behavior. Given the link between gut microbiota, body composition, obesity, and anxiety, the aim of this study was to evaluate the effects of a new psychobiotic formulation. Methods:Eligible pa...

journal_title：Mediators of inflammation

authors： Colica C,Avolio E,Bollero P,Costa de Miranda R,Ferraro S,Sinibaldi Salimei P,De Lorenzo A,Di Renzo L

更新日期：2017-01-01 00:00:00

abstract：:Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host's proteins. Antigens and their immune complexes (IC) may shape macrophage phenotype in various directions. Data on the impact of protein structure during inflammati...

journal_title：Mediators of inflammation

authors： Dalgėdienė I,Lučiūnaitė A,Žvirblienė A

更新日期：2018-11-18 00:00:00

abstract：:In addition to the spectrum of biological action already known to be exhibited by acetylsalicylic acid (ASA) as an analgesic, anti-inflammatory and platelet aggregation inhibitor, there is growing evidence of a stimulatory effect on the immune system. ASA has been found to increase the production ofcytokines and to in...

journal_title：Mediators of inflammation

authors： Jäpel M,Lötzerich H,Rogalla K

更新日期：1994-01-01 00:00:00

abstract：:We investigated the serum concentrations of interleukin-6 (IL-6) and two IL-6 family of cytokines (leukaemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) as well as IL-6 soluble receptor (sIL-6R) using an enzyme-linked immunosorbent assay (ELISA) in 66 patients with rheumatoid arthritis (RA) and 24 h...

journal_title：Mediators of inflammation

authors： Robak T,Gladalska A,Stepień H,Robak E

更新日期：1998-01-01 00:00:00

abstract：:Dysfunction of the blood-brain barrier (BBB) is a primary characteristic of experimental autoimmune encephalomyelitis (EAE), an experimental model of multiple sclerosis (MS). Matrine (MAT), a quinolizidine alkaloid derived from the herb Radix Sophorae Flave, has been recently found to suppress clinical EAE and CNS inf...

journal_title：Mediators of inflammation

authors： Zhang S,Kan QC,Xu Y,Zhang GX,Zhu L

更新日期：2013-01-01 00:00:00

abstract：:The causes of retinal hypoxia are many and varied. Under hypoxic conditions, a variety of soluble factors are secreted into the vitreous cavity including growth factors, cytokines, and chemokines. Cytokines, which usually serve as signals between neighboring cells, are involved in essentially every important biologica...

journal_title：Mediators of inflammation

authors： dell'Omo R,Semeraro F,Bamonte G,Cifariello F,Romano MR,Costagliola C

更新日期：2013-01-01 00:00:00

abstract：:Surgery induces release of neuroendocrine hormones (cortisol), cytokines (interleukin-6: IL-6, tumour necrosis factor-alpha: TNF-alpha), acute phase proteins (C-reactive protein: CRP, leptin). We studied the effects of general and spinal anaesthesia on stress response to haemorrhoidectomy. Patients were assigned to ge...

journal_title：Mediators of inflammation

authors： Buyukkocak U,Caglayan O,Daphan C,Aydinuraz K,Saygun O,Agalar F

更新日期：2006-01-01 00:00:00

abstract：:Tumor necrosis factor alpha (TNF-α) is a cytokine which plays opposing roles in the context of infectious disease pathogenesis. TNF-α is essential for the development of a protective immune response to some pathogens, for example, Mycobacterium tuberculosis, by synergizing with other cytokines. However, exorbitant or ...

journal_title：Mediators of inflammation

authors： Dirisala VR,Jeevan A,Ly LH,McMurray DN

更新日期：2015-01-01 00:00:00

abstract：AIM:To determine gastric tissue lactoferrin (Lf) levels of Helicobacter pylori- (Hp-) positive and -negative patients and its effect on anemia. METHODS:Cases in which initial presentation was of abdominal pain and that were Hp-positive at endoscopy were included. Hp-positive cases and -negative controls were divided i...

journal_title：Mediators of inflammation

authors： Doğan Y,Erkan T,Önal Z,Usta M,Doğusoy G,Çokuğraş FÇ,Kutlu T

更新日期：2012-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of multiple joints. The central pathogenesis of RA is the proliferation of synovial fibroblasts in response to inflammatory cytokines. However, some of the targeted therapies for inflammation reactions do not display signi...

journal_title：Mediators of inflammation

authors： Yin G,Wang Y,Cen XM,Yang M,Liang Y,Xie QB

更新日期：2015-01-01 00:00:00

abstract：:The observed effects after ozone exposure strongly depend on ozone concentration and exposure time. We hypothesized that depending on the O3 exposure protocol, mainly either an oxidant damage or an inflammation will determine the O3 toxicity. We compared two different ozone exposure protocols: an acute exposure (3 ppm...

journal_title：Mediators of inflammation

authors： van Hoof HJ,Zijlstra FJ,Voss HP,Garrelds IM,Dormans JA,van Bree L,Bast A

更新日期：1997-01-01 00:00:00

abstract：:The effects of intravenous injection of Porphyromonas gingivalis (Pg) on rabbit inflammatory immune response and atherosclerosis were evaluated by establishing a microamount Pg bacteremia model combined with high-fat diet. Twenty-four New Zealand rabbits were randomly divided into Groups A-D (n = 6). After 14 weeks, l...

journal_title：Mediators of inflammation

authors： Lin G,Chen S,Lei L,You X,Huang M,Luo L,Li Y,Zhao X,Yan F

更新日期：2015-01-01 00:00:00

abstract：:Current studies have identified the multifaceted protective functions of dexmedetomidine on multiple organs. For the first time, we clarify effects of dexmedetomidine on monocyte-endothelial adherence and whether its underlying mechanism is relative to connexin43 (Cx43), a key factor regulating monocyte-endothelial ad...

journal_title：Mediators of inflammation

authors： Chai Y,Yu R,Liu Y,Wang S,Yuan D,Chen J

更新日期：2020-02-10 00:00:00

abstract：:Lysophosphatidic acid (LPA) is a bioactive phospholipid playing an important role in various inflammatory diseases by inducing expression and secretion of many inflammatory cytokines/chemokines. Here we report in a murine air pouch model of inflammation that LPA induced CXCL13 secretion in a time-dependent manner and ...

journal_title：Mediators of inflammation

authors： Hui W,Zhao C,Bourgoin SG

更新日期：2015-01-01 00:00:00

abstract：:Matrix metalloproteinase 9 is a proteolytic enzyme which is recently one of the more often studied biomarkers. Its possible use as a biomarker of neuronal damage in stroke, heart diseases, tumors, multiple sclerosis, and epilepsy is being widely indicated. In epilepsy, MMP-9 is suggested to play a role in epileptic fo...

journal_title：Mediators of inflammation

authors： Bronisz E,Kurkowska-Jastrzębska I

更新日期：2016-01-01 00:00:00

abstract：:Inflammation represents the immune system response to external or internal aggressors such as injury or infection in certain tissues. The body's response to cancer has many parallels with inflammation and repair; the inflammatory cells and cytokines present in tumours are more likely to contribute to tumour growth, pr...

journal_title：Mediators of inflammation

authors： Albulescu R,Codrici E,Popescu ID,Mihai S,Necula LG,Petrescu D,Teodoru M,Tanase CP

更新日期：2013-01-01 00:00:00

abstract：:Background. Neutrophilic bronchial inflammation is a main feature of bronchiectasis, but not much is known about its relationship with other disease features. Aim. To compare airway inflammatory markers with clinical and functional findings in subjects with stable noncystic fibrosis bronchiectasis (NCFB). Methods. 152...

journal_title：Mediators of inflammation

authors： Dente FL,Bilotta M,Bartoli ML,Bacci E,Cianchetti S,Latorre M,Malagrinò L,Nieri D,Roggi MA,Vagaggini B,Paggiaro P

更新日期：2015-01-01 00:00:00

abstract：:Inflammatory response in Chagas disease is related to parasite and host factors. However, immune system regulation has not been fully elucidated. Thus, this study is aimed at evaluating IL-4 influence on acute phase of Trypanosoma cruzi experimental infection through dosage of cytokine levels in cardiac homogenate of ...

journal_title：Mediators of inflammation

authors： da Silva MV,de Almeida VL,de Oliveira WD,Matos Cascudo NC,de Oliveira PG,da Silva CA,da Silva ACS,Dos Reis Monteiro MLG,Correa RRM,Oliveira MAP,Lino-Júnior RS,Celes MRN,Machado JR

更新日期：2018-11-28 00:00:00