Importance of CD4+ helper T-cells in antitumor immunity.

Abstract:

:CD8+ cytotoxic T-lymphocytes are major effector cells involved in immunologically specific tumor destruction in vivo, and CD4+ T-cells are essential for controlling this CD8+ T-cell-dependent tumor eradication. The presence of CD4+ T-cells with distinct functional roles has been recognized. The further understanding of the complexity of antitumor immune responses by CD4+ T-cells may be crucial for designing more effective cancer vaccines.

journal_name

Int J Hematol

authors

Shiku H

doi

10.1007/BF02986610

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

435-8

issue

5

eissn

0925-5710

issn

1865-3774

journal_volume

77

pub_type

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