Abstract：
:The spore is the form released in a bioterrorism attack. There is a real need for definition of new targets for Bacillus anthracis that might be incorporated into emerging biodetection technologies. Particularly of interest are macromolecules found in B. anthracis that are (1) spore-specific, (2) readily accessible on the spore surface and (3) distinct from those present in related organisms. One of the few biochemical methods to identify the spores of B. anthracis is based on the presence of rhamnose and 3-O-methyl rhamnose as determined by gas chromatography-mass spectrometry. Related organisms additionally contain 2-O-methyl rhamnose and fucose. Carbohydrates and glycoproteins of the B. cereus group of organisms and the related B. subilis group are reviewed here. It is hypothesized that the spore-specific carbohydrate is a component of the newly described glycoprotein of the exosporium of B. anthracis. Further work to define the protein and carbohydrate components of the glycoprotein of B. anthracis could be highly useful in developing new technologies for rapid biodetection.
journal_name
J Microbiol Methodsjournal_title
Journal of microbiological methodsauthors
Fox A,Stewart GC,Waller LN,Fox KF,Harley WM,Price RLdoi
10.1016/s0167-7012(03)00095-2subject
Has Abstractpub_date
2003-08-01 00:00:00pages
143-52issue
2eissn
0167-7012issn
1872-8359pii
S0167701203000952journal_volume
54pub_type
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