Abstract:
:Flow cytometric analysis of human platelets from healthy volunteers by high-resolution immunophenotyping accomplished with enzymatic amplification staining revealed the expression of CD34. Assessment of the platelets with five different monoclonal antibodies to the three different classes of CD34 epitopes suggested that platelets express a unique glycoform of the molecule. Expression of CD34 was verified by immunoblotting. Platelet activation resulted in a marked decrease in surface CD34. CD34 expression has significant implications for the function of platelets as well as for the determination of hematopoietic progenitor cells.
journal_name
Plateletsjournal_title
Plateletsauthors
Lewandowska K,Kaplan D,Husel Wdoi
10.1080/0953710031000080577subject
Has Abstractpub_date
2003-03-01 00:00:00pages
83-7issue
2eissn
0953-7104issn
1369-1635pii
26GYFYYA674B1CXHjournal_volume
14pub_type
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