Functional topography of connections linking mirror-symmetric maps in the mouse olfactory bulb.

Abstract:

:In rodents, each main olfactory bulb contains two mirror-symmetric glomerular maps, a feature not found in the initial topographic maps of other sensory systems. Targeting tracer injections to identified glomeruli revealed that isofunctional odor columns-translaminar assemblies connected to a given glomerulus-were specifically and reciprocally interconnected through a mutually inhibitory circuit with exquisite topographic specificity. Thus, instead of containing two mirror-symmetric maps, we propose that the olfactory bulb contains a single integrated map in which isofunctional odor columns are connected through an intrabulbar link, analogous to the specific horizontal connections linking iso-orientation columns in primary visual cortex.

journal_name

Neuron

journal_title

Neuron

authors

Lodovichi C,Belluscio L,Katz LC

doi

10.1016/s0896-6273(03)00194-6

subject

Has Abstract

pub_date

2003-04-24 00:00:00

pages

265-76

issue

2

eissn

0896-6273

issn

1097-4199

pii

S0896627303001946

journal_volume

38

pub_type

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