Evaluation of endotoxin content of diphtheria-tetanus-acellular pertussis combined (DTaP) vaccines that interfere with the bacterial endotoxin test.

abstract：:Immunization with xenogeneic DNA is a promising cancer treatment to overcome tolerance to self-antigens. Heat shock protein 70 (HSP70) is over-expressed in various kinds of tumors and is believed to be involved in tumor progression. This study tested a xenogeneic chicken HSP70 (chHSP70) DNA vaccine in an experimental ...

journal_title：Vaccine

authors： Yu WY,Chuang TF,Guichard C,El-Garch H,Tierny D,Laio AT,Lin CS,Chiou KH,Tsai CL,Liu CH,Li WC,Fischer L,Chu RM

更新日期：2011-04-18 00:00:00

abstract：:Forty-four adult patients with cutaneous leishmaniasis (CL) were enrolled in a randomized, double-blind, controlled, dose-escalating clinical trial and were randomly assigned to receive three injections of either the LEISH-F1+MPL-SE vaccine (consisting of 5, 10, or 20 μg recombinant Leishmania polyprotein LEISH-F1 ant...

journal_title：Vaccine

authors： Nascimento E,Fernandes DF,Vieira EP,Campos-Neto A,Ashman JA,Alves FP,Coler RN,Bogatzki LY,Kahn SJ,Beckmann AM,Pine SO,Cowgill KD,Reed SG,Piazza FM

更新日期：2010-09-14 00:00:00

abstract：BACKGROUND:Invasive pneumococcal disease and respiratory tract infections are both frequent and severe in patients with systemic lupus erythematosus (SLE). This study aimed to compare the immunological efficacy and safety of pneumococcal vaccination with the 23-valent polysaccharide (PPS) vaccine alone to a sequential ...

journal_title：Vaccine

authors： Grabar S,Groh M,Bahuaud M,Le Guern V,Costedoat-Chalumeau N,Mathian A,Hanslik T,Guillevin L,Batteux F,Launay O,VACCILUP study group.

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Pseudotuberculosis is an infection caused by the bacterial enteropathogen Yersinia pseudotuberculosis and is considered to be a significant problem in veterinary medicine. We previously found that intranasal administration of a recombinant Lactococcus lactis strain that secretes the low-calcium response V (L...

journal_title：Vaccine

authors： Daniel C,Titecat M,Poiret S,Cayet D,Boutillier D,Simonet M,Sirard JC,Lemaître N,Sebbane F

更新日期：2016-11-11 00:00:00

abstract：:The currently used live-attenuated measles vaccine is very effective although maternal antibody prevents its administration prior to 6 months of age. We are investigating the ability of a DNA vaccine encoding the measles viral hemagglutinin, fusion and nucleoprotein to protect newborn infants from measles. Here, we sh...

journal_title：Vaccine

authors： Premenko-Lanier M,Rota P,Rhodes G,Bellini W,McChesney M

更新日期：2004-01-26 00:00:00

abstract：:The aim of this work was to evaluate the microencapsulation by spray-drying of inactivated Vibrio cholerae, using methacrylic copolymers Eudragit® L30D-55 and FS30D. The microparticles obtained presented a particle size around 3.0 μm. The preparation temperature affected the morphology and the antigenicity of micropar...

journal_title：Vaccine

authors： Año G,Esquisabel A,Pastor M,Talavera A,Cedré B,Fernández S,Sifontes S,Aranguren Y,Falero G,García L,Solís RL,Pedraz JL

更新日期：2011-08-05 00:00:00

abstract：:A major challenge for poultry vaccination is the design of vaccines that protect against multiple pathogens via a single protective dose delivered through mass vaccination methods. In this investigation, we examined herpesvirus of turkeys (HVT) as a vaccine vector for delivery of haemagglutinin (HA) antigen of highly ...

journal_title：Vaccine

authors： Li Y,Reddy K,Reid SM,Cox WJ,Brown IH,Britton P,Nair V,Iqbal M

更新日期：2011-10-26 00:00:00

abstract：:Pertactin/P.69, a surface-associated polypeptide antigen of Bordetella pertussis, was expressed in a Salmonella typhimurium aroA aroD vaccine strain, BRD509, using different expression systems, and the immune response in mice against these constructs was compared. Initially, Pertactin/P.69 was expressed on the surface...

journal_title：Vaccine

authors： Anderson R,Dougan G,Roberts M

更新日期：1996-10-01 00:00:00

abstract：:Measles, mumps, rubella and varicella are viral infections which can implicate seriously long-term sequelae of infected individuals or even the unborn child. Vaccines against the individual diseases have long been available. Global measles vaccination is estimated to have prevented more than 20million deaths during 20...

journal_title：Vaccine

authors： Kowalzik F,Faber J,Knuf M

更新日期：2018-08-28 00:00:00

abstract：:Hepatitis A caused by hepatitis A virus (HAV) transmitted by the fecal-oral route, results in considerable morbidity and economic loss. Mucosal immunization can be more effective than conventional injection at inducing both local and systemic immunity to HAV. Here we show that co-administration of killed HAV with synt...

journal_title：Vaccine

authors： Mitchell LA,Joseph A,Kedar E,Barenholz Y,Galun E

更新日期：2006-06-19 00:00:00

abstract：BACKGROUND:Coverage levels for many recommended adult vaccinations are low. The cost-effectiveness research literature on adult vaccinations has not been synthesized in recent years, which may contribute to low awareness of the value of adult vaccinations and to their under-utilization. We assessed research literature ...

journal_title：Vaccine

authors： Leidner AJ,Murthy N,Chesson HW,Biggerstaff M,Stoecker C,Harris AM,Acosta A,Dooling K,Bridges CB

更新日期：2019-01-07 00:00:00

abstract：:The role of disulfide-dependent protein conformation of the 195,000 kDa Plasmodium falciparum merozoite surface glycoprotein in the induction of biologically active antibodies was investigated. Serum samples from rabbits immunized with native gp195 had a mean ELISA titre of 1/560,000 and a mean in vitro parasite growt...

journal_title：Vaccine

authors： Locher CP,Tam LQ

更新日期：1993-01-01 00:00:00

abstract：:The availability of an inactivated hepatitis A virus (HAV) vaccine, and the development of live attenuated virus vaccines against hepatitis represent great advances in the effort to control an important cause of viral hepatitis. There are a number of ways hepatitis A vaccines could be used, depending on the epidemiolo...

journal_title：Vaccine

authors： Kane MA

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Persons with primary immunodeficiency disorders (PIDD) who receive oral poliovirus vaccine (OPV) or are household contacts of OPV recipients are at risk of excreting immunodeficiency-associated vaccine-derived polioviruses (iVDPVs). iVDPVs can be transmitted and cause paralytic polio. The objective of this s...

journal_title：Vaccine

authors： Sazzad HM,Rainey JJ,Mach O,Sutter R,Diordista S,Kawser CA,Mobarak R,Alam D,Chowdhury MA,Hossain MJ,Hasan AS,Luby SP

更新日期：2012-08-03 00:00:00

abstract：:As sensitivity to erythritol is the main feature of the Brucella abortus B19 vaccine strain, an attempt to define the genetic basis of this phenotypic trait was made in order to explore its usefulness as a means of molecular identification of strain B19. With this purpose, an erythritol-sensitive derivative of B. abor...

journal_title：Vaccine

authors： Sangari FJ,Agüero J

更新日期：1994-04-01 00:00:00

abstract：:Uncertainty regarding the benefits of influenza vaccination may contribute to the underutilization of this vaccine. We have conducted serial cohort studies using the administrative data bases of a Twin Cities based managed care organization to assess the impact of disease and benefits of vaccination among the elderly....

journal_title：Vaccine

authors： Nichol KL

更新日期：1999-07-30 00:00:00

abstract：:HPV vaccination schedules have changed as evidence has supported reduced dosing and extended intervals. Women living with HIV (WLWH) represent an important population with no data on alternative dosing. Girls and WLWH received quadrivalent HPV (qHPV) vaccine in a pan-Canadian study of immunogenicity and efficacy. Sero...

journal_title：Vaccine

authors： McClymont E,Ogilvie G,Albert A,Johnston A,Raboud J,Walmsley S,Lipsky N,Loutfy M,Trottier S,Smaill F,Yudin MH,Klein MB,Harris M,Wobeser W,Bitnun A,Kakkar F,Samson L,Brophy J,Karatzios C,Money D,CTN 236 HPV in HIV S

更新日期：2020-03-30 00:00:00

abstract：:Flagellin of Pseudomonas aeruginosa is an important vaccine candidate. N-terminal domains are highly conserved in both type a and type b flagellins. The efficacy of gold nanoparticles (AuNPs) conjugated to N-terminal domains of P. aeruginosa flagellin (flagellin(1-161)), as an immunogen in mice, has been assessed. The...

journal_title：Vaccine

authors： Dakterzada F,Mohabati Mobarez A,Habibi Roudkenar M,Mohsenifar A

更新日期：2016-03-14 00:00:00

abstract：OBJECTIVES:Yearly vaccination against influenza is currently recommended to patients with rheumatoid Arthritis (RA). Antibody and cell-mediated responses are both involved in the defense against influenza. Humoral responses to influenza vaccine are impaired in RA patients treated with rituximab (RTX). The objectives of...

journal_title：Vaccine

authors： Arad U,Tzadok S,Amir S,Mandelboim M,Mendelson E,Wigler I,Sarbagil-Maman H,Paran D,Caspi D,Elkayam O

更新日期：2011-02-11 00:00:00

abstract：:Rabies is an ancient zoonosis that continues to be an important health problem worldwide. Vaccination with rabies vaccine is the most important strategy to prevent rabies. Adjuvants contribute to the immune response of viral vaccine. The aim of this study was to investigate whether artemisinin derivatives artesunate a...

journal_title：Vaccine

authors： Luo J,Zhang Y,He H,Liu Q,Huang S,Guo X

更新日期：2019-12-03 00:00:00

abstract：:Tick-borne encephalitis (TBE) is a potentially serious disease, especially in adults. There is no treatment available for TBE; supportive therapy may help to ease symptoms of the disease. Vaccination is the most effective method of preventing TBE disease and is recommended for those who live, work, or travel in TBE-en...

journal_title：Vaccine

authors： Plentz A,Jilg W,Schwarz TF,Kuhr HB,Zent O

更新日期：2009-02-05 00:00:00

abstract：:Phage lambda particles displaying four immunodominant regions of porcine Circovirus 2 (PCV2) capsid protein (LDP-D-CAP) was shown to be immunogenic in pigs. The immunodominant regions were fused to the carboxyl-terminal of lambda head protein D. Expression of D-CAP on lambda display particles was demonstrated by ELISA...

journal_title：Vaccine

authors： Gamage LN,Ellis J,Hayes S

更新日期：2009-11-05 00:00:00

abstract：:The goal of the present study was to evaluate the influence of the influenza A H1N1/2009 vaccine on dermatomyositis/polymyositis (DM/PM) disease parameters and the potential deleterious effect of therapy on immune response. Thirty-seven DM and 21 PM patients (Bohan and Peter's criteria) were gender- and age-matched to...

journal_title：Vaccine

authors： Shinjo SK,de Moraes JC,Levy-Neto M,Aikawa NE,de Medeiros Ribeiro AC,Schahin Saad CG,Precioso A,Silva CA,Bonfá E

更新日期：2012-12-17 00:00:00

abstract：:Carbopol is a polyanionic carbomer used in man for topical application and drug delivery purposes. However parenteral administration of Carbopol in animal models results in systemic adjuvant activity including strong pro-inflammatory type-1 T-cell (Th1) polarization. Here we investigated potential pathways of immune a...

journal_title：Vaccine

authors： Gartlan KH,Krashias G,Wegmann F,Hillson WR,Scherer EM,Greenberg PD,Eisenbarth SC,Moghaddam AE,Sattentau QJ

更新日期：2016-04-27 00:00:00

abstract：:Immunization with amyloid-beta (Abeta) peptide reduces amyloid load in animal studies and in humans; however clinical trials resulted in the development of a pro-inflammatory cellular response to Abeta. Apoptosis has been employed to stimulate humoral and Th2-biased cellular immune responses. Thus, we sought to invest...

journal_title：Vaccine

authors： DaSilva KA,Brown ME,McLaurin J

更新日期：2009-02-25 00:00:00

abstract：BACKGROUND:China is the most populous country in the world, with an annual birth cohort of approximately 16 million, requiring an average of 500 million vaccine doses administered annually. In China, over 30 domestic and less than 10 overseas vaccine manufacturers supply over 60 licensed vaccine products, representing ...

journal_title：Vaccine

authors： Guo B,Page A,Wang H,Taylor R,McIntyre P

更新日期：2013-01-11 00:00:00

abstract：:Immunologically based fertility control vaccines against zona pellucida (ZP) proteins are being developed in New Zealand for biocontrol of the brushtail possum (Trichosurus vulpecula), an introduced Australian marsupial pest. We have shown that immunization of female possums with recombinant possum ZP3 protein (rZP3) ...

journal_title：Vaccine

authors： Cui X,Duckworth JA,Molinia FC,Cowan PE

更新日期：2010-02-10 00:00:00

abstract：:Salmonellae are commonly isolated from dogs. The number of dogs infected with Salmonella spp. is surprisingly high and greater than the incidence of clinical disease would suggest. Salmonellosis is common in greyhound kennels. Morbidity can approach 100% in puppies and the mortality ranges to nearly 40%. To date, ther...

journal_title：Vaccine

authors： McVey DS,Chengappa MM,Mosier DE,Stone GG,Oberst RD,Sylte MJ,Gabbert NM,Kelly-Aehle SM,Curtiss R

更新日期：2002-02-22 00:00:00

abstract：:Designation as a Category B biothreat agent has propelled Coxiella burnetii from a relatively obscure, underappreciated, "niche" microorganism on the periphery of bacteriology, to one of possibly great consequence if actually used in acts of bioterrorism. Advances in the study of this microorganism proceeded slowly, p...

journal_title：Vaccine

authors： Waag DM

更新日期：2007-10-16 00:00:00

abstract：:Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a potent immune stimulant when administered with different vaccines. Optimal use of GM-CSF resides in its ability to act locally to stimulate the proliferation and maturation of professional antigen-presenting cells (APCs) (i.e., Langerhans' cells) at the in...

journal_title：Vaccine

authors： Reali E,Canter D,Zeytin H,Schlom J,Greiner JW

更新日期：2005-04-22 00:00:00