Expression of a thioredoxin peroxidase in insulin-producing cells.

abstract：AIM:To investigate the effect of changes in fasting plasma glucose (FPG) variability, as assessed by 2-year trajectories of FPG variability, on mortality risk in patients with type 2 diabetes (T2D). METHODS:From 2009 to 2012, outpatients with T2D, aged>18 years, were enrolled from a medical centre. FPG was measured ev...

journal_title：Diabetes & metabolism

authors： Lee CL,Sheu WH,Lee IT,Lin SY,Liang WM,Wang JS,Li YF

更新日期：2018-03-01 00:00:00

abstract：:Although diabetes is a classical risk factor for macroangiopathy, the prevalence of renal artery stenosis (RAS) in this type of pathology has not been clearly determined. More than 50% of RAS occur in diabetic patients (almost exclusively Type 2), whereas autopsy findings and the few clinical surveys reported indicate...

journal_title：Diabetes & metabolism

authors： Otal P,Janne D'othee B,Chabbert V,Meites G,Rousseau H,Joffre F

更新日期：2000-07-01 00:00:00

abstract：AIMS:Trimethylamine N-oxide (TMAO), choline and betaine serum levels have been associated with metabolic diseases including type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD). These associations could be mediated by insulin resistance. However, the relationships among these metabolites, insulin resista...

journal_title：Diabetes & metabolism

authors： León-Mimila P,Villamil-Ramírez H,Li XS,Shih DM,Hui ST,Ocampo-Medina E,López-Contreras B,Morán-Ramos S,Olivares-Arevalo M,Grandini-Rosales P,Macías-Kauffer L,González-González I,Hernández-Pando R,Gómez-Pérez F,Campos-Pérez F,

更新日期：2020-08-10 00:00:00

abstract：AIM:Online continuous glucose monitoring (CGM) during physical exercise would be highly useful in patients with insulin-treated diabetes. For this reason, this study assessed whether such a goal could be reached with a subcutaneous 'needle-type' enzymatic sensor. METHODS:Ten patients (five women/five men), aged 51 ± 1...

journal_title：Diabetes & metabolism

authors： Radermecker RP,Fayolle C,Brun JF,Bringer J,Renard E

更新日期：2013-05-01 00:00:00

abstract：AIM:Our objective was to verify the energy balance in streptozotocin-induced diabetic rats chronically treated with lipoic acid (LA). METHODS:Diabetes was induced in rats by streptozotocin and the animals divided into four groups, comprising controls and diabetic rats, with each group receiving either daily intraperit...

journal_title：Diabetes & metabolism

authors： Luz J,Zemdegs JC,Amaral LS

更新日期：2009-04-01 00:00:00

abstract：:The timely series of state-of-the-art reviews contained within this supplement provide a valuable overview of the current state of diabetes care, and the pharmacological interventions we have available. Our experts agree that one of the most important lessons to emerge recently concerns the magnitude of the malign inf...

journal_title：Diabetes & metabolism

authors： Standl E

更新日期：2003-09-01 00:00:00

abstract：AIMS:To evaluate factors associated with reaching or not reaching target glycated haemoglobin (HbA1c) levels by analysing the respective contributions of fasting hyperglycaemia (FHG), also referred to as basal hyperglycaemia, vs postprandial hyperglycaemia (PHG) before and after initiation of a basal or premixed insuli...

journal_title：Diabetes & metabolism

authors： Scheen AJ,Schmitt H,Jiang HH,Ivanyi T

更新日期：2017-02-01 00:00:00

abstract：AIM:To investigate the balance between parameters of oxidative stress and antioxidant defences in the mitochondria of peripheral blood mononuclear cells (PBMCs) of type 2 diabetic patients with late complications. METHODS:Ten type 2 diabetic patients with late diabetic complications and 10 age-matched healthy voluntee...

journal_title：Diabetes & metabolism

authors： García-Ramírez M,Francisco G,García-Arumí E,Hernández C,Martínez R,Andreu AL,Simó R

更新日期：2008-04-01 00:00:00

abstract：:Protease inhibitor treatment has dramatically improved rates of morbidity and mortality in HIV-infected patients. However, it has recently been shown that this medication is associated with long-term side effects characterized by metabolic, clinical and biological alterations. These modifications have been described i...

journal_title：Diabetes & metabolism

authors： Vigouroux C,Gharakhanian S,Salhi Y,Nguyên TH,Adda N,Rozenbaum W,Capeau J

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:In patients with type 2 diabetes (T2D), glycaemic variability (GV), another component of glycaemic abnormalities, is a novel potentially aggravating factor for coronary artery disease (CAD). OBJECTIVES:The aim of our study was to identify interactions between GV and severity of CAD in diabetes patients admi...

journal_title：Diabetes & metabolism

authors： Benalia M,Zeller M,Mouhat B,Guenancia C,Yameogo V,Greco C,Yao H,Maza M,Vergès B,Cottin Y

更新日期：2019-10-01 00:00:00

abstract：:The project to finalize a 'closed loop' insulin delivery according to blood glucose level, i.e. an implanted artificial beta cell, is born from the development of the first miniaturized portable insulin pumps during the 1970s. Continuous improvements in micro-electronics, as well as in the development of biomaterials ...

journal_title：Diabetes & metabolism

authors： Renard E,Costalat G,Bringer J

更新日期：2002-09-01 00:00:00

abstract：AIM:To investigate the association between mean fasting glucose (FG) and variability in visit-to-visit FG and risk of mortality in people with type 2 diabetes (T2D). METHODS:This retrospective cohort study included 48,077 Chinese men and women with T2D. The yearly mean and coefficient of variation for fasting glucose ...

journal_title：Diabetes & metabolism

authors： Xu H,Zhang Y,Xu W,Chen L,Zhang M,Su H,Cheng Y,Zhao N,Xu D,Qin G

更新日期：2020-05-26 00:00:00

abstract：AIM:Adiponectin levels in skeletal muscle and adipose tissue have been reported to be involved in insulin resistance in rats fed with a high-fat diet (HFD). Our objective was to explore whether adiponectin is also expressed in the pancreas and what its potential role is during the development of type 2 diabetes (T2D) i...

journal_title：Diabetes & metabolism

authors： Liu XX,Liu KY,Li P,Han S,Peng XD,Shen L

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of a patient education program on diabetes control. METHODS:A pre-test post-test pre experimental study was performed with 87 insulin treated diabetic patients followed in the chronic disease unit of Kelibia district (Nabeul, Tunisia). Subjects received education in 6 monthly sess...

journal_title：Diabetes & metabolism

authors： Jenhani M,Gaha K,Nabouli R,Ghedira A,Ben Abdelaziz A

更新日期：2005-09-01 00:00:00

abstract：:Hypertension is a major cardiovascular risk factor in diabetic subjects. Recent trials have suggested that blood pressure objectives should be < or = 140/80 mmHg. However, there is currently no evidence supporting any particular preferential drug strategy for this treatment objective. ...

journal_title：Diabetes & metabolism

authors： Marre M,Bouhanick B,Hadjadj S,Weekers L

更新日期：1999-06-01 00:00:00

abstract：:The effect of propranolol on the occurrence of hypoglycaemic symptoms was assessed in insulin-dependent diabetic patients with hypoglycaemia unawareness. A double-blind, randomised parallel group study (2:1 fashion) was conducted over 4-week period. The propranolol group (n = 9) received 20 mg (week 1 and 2) and 30 mg...

journal_title：Diabetes & metabolism

authors： Chalon S,Berlin I,Sachon C,Bosquet F,Grimaldi A

更新日期：1999-03-01 00:00:00

abstract：AIM:The best way to treat pregnant patients who have type 1 diabetes is still unclear. For this reason, the present study compared metabolic control and maternal-fetal outcomes in patients treated with continuous subcutaneous infusions of rapid-acting insulin analogues (CSII) or with insulin glargine and multiple daily...

journal_title：Diabetes & metabolism

authors： Bruttomesso D,Bonomo M,Costa S,Dal Pos M,Di Cianni G,Pellicano F,Vitacolonna E,Dodesini AR,Tonutti L,Lapolla A,Di Benedetto A,Torlone E,Italian Group for Continuous Subcutaneous Insulin Infusion in Pregnancy.

更新日期：2011-11-01 00:00:00

abstract：AIM:The objective of the study was to examine the correlation between three methods of measuring insulin sensitivity (IS) - namely, the frequently sampled intravenous glucose tolerance test (FSIVGTT), indices derived from the oral glucose tolerance test (OGTT) and fasting indices (HOMA-IR, QUICKI, fasting insulin [INS(...

journal_title：Diabetes & metabolism

authors： Henderson M,Rabasa-Lhoret R,Bastard JP,Chiasson JL,Baillargeon JP,Hanley JA,Lambert M

更新日期：2011-02-01 00:00:00

abstract：AIM:To describe current practices of glucose-lowering treatments in people with diabetes and chronic kidney disease (CKD), the associated glucose control and hypoglycaemic symptoms, with an emphasis on sex differences. METHODS:Among the 3033 patients with CKD stages 3-5 recruited into the French CKD-REIN study, 645 me...

journal_title：Diabetes & metabolism

authors： Balkau B,Metzger M,Andreelli F,Frimat L,Speyer E,Combe C,Laville M,Jacquelinet C,Briançon S,Ayav C,Massy Z,Pisoni RL,Stengel B,Fouque D

更新日期：2019-04-01 00:00:00

abstract：:TNF-alpha is considered as one of the potential determinants of insulin resistance. However several data suggest that TNF-alpha expression itself, could be modulated by the degree of adiposity and/or plasma insulin levels. To clarify the determinants of plasma TNF-alpha levels in type 2 diabetes mellitus, we studied t...

journal_title：Diabetes & metabolism

authors： Bertin E,Nguyen P,Guenounou M,Durlach V,Potron G,Leutenegger M

更新日期：2000-05-01 00:00:00

abstract：:Continuous subcutaneous insulin infusion (CSII) using an external pump is widely used for the treatment of type 1 diabetes, but has been less evaluated in type 2 diabetes. This review analyzes the open-label as well as randomized controlled studies performed in type 2 diabetic patients. The efficacy of CSII is compare...

journal_title：Diabetes & metabolism

authors： Reznik Y

更新日期：2010-12-01 00:00:00

abstract：AIMS:To evaluate the current procedures in French general practice of intensifying hypoglycaemic treatment in orally treated type 2 diabetic patients, according to the French recommendations. METHODS:Type 2 diabetic patient characteristics, HbA(1c) values, hypoglycaemic treatment and physician characteristics were col...

journal_title：Diabetes & metabolism

authors： Balkau B,Bouée S,Avignon A,Vergès B,Chartier I,Amelineau E,Halimi S

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:To calculate an adjusted maternal weight gain during pregnancy including infant and placental weights to the actual weight gain and secondarily examine its influence on the occurrence of fetal macrosomia. METHODS:The corrected weight gain was calculated as follows: maternal body weight at the last prenatal ...

journal_title：Diabetes & metabolism

authors： Lepercq J,Hauguel-De Mouzon S,Timsit J,Catalano PM

更新日期：2002-09-01 00:00:00

abstract：:The CGMS (Continuous Glucose Monitoring System) is a portable device allowing continuous measuring of glucose. It provides recordings of at least 72 h, during which 288 measures/day are performed. Results are visualised in the form of a set of curves, illustrating the variations in blood glucose levels over time. The ...

journal_title：Diabetes & metabolism

authors： Melki V,Ayon F,Fernandez M,Hanaire-Broutin H

更新日期：2006-04-01 00:00:00

abstract：AIM:The clinical guidelines reported by the French-Speaking Diabetes Society (Société francophone du diabète) include updated recommendations for preconceptual planning and care in the management of pregnancy in women with type 1 diabetes mellitus (T1DM). METHODS:The working group included diabetologists, as well as a...

journal_title：Diabetes & metabolism

authors： Bismuth E,Bouche C,Caliman C,Lepercq J,Lubin V,Rouge D,Timsit J,Vambergue A,French-Speaking Diabetes Society.

更新日期：2012-06-01 00:00:00

abstract：:Hypoglycaemia unawareness, a frequent syndrome in insulin-dependent diabetes mellitus (IDDM), involves a decrease or absence of perception of specific symptoms which normally inform the subject that plasma glucose is decreasing to dangerous levels leading to neuroglycopenia. Without warning symptoms, IDDM patients are...

journal_title：Diabetes & metabolism

authors： Bolli GB

更新日期：1997-09-01 00:00:00

abstract：AIM:Kidney hypoxia can predispose to the development of acute and chronic renal failure in diabetes. Ischaemia-reperfusion injury (IRI) causes inflammation, and diabetes is known to exacerbate this inflammatory response in the kidney, whereas alarmin IL-33 could act as an innate immune mediator during kidney IRI. Thus,...

journal_title：Diabetes & metabolism

authors： Sehnine M,Ferhat M,Sena S,Gombert JM,Goujon JM,Thierry A,Touchard G,Hauet T,Herbelin A,Hadjadj S

更新日期：2018-02-01 00:00:00

abstract：:The "Société Française de Gériatrie et Gérontologie" (SFGG) and "Association de Langue Française pour l'Etude du Diabète et des Maladies Métaboliques" (ALFEDIAM) have decided to join their efforts in actions to improve the management and treatment of the elderly diabetic patients. New knowledge brought by the fundamen...

journal_title：Diabetes & metabolism

authors： Tréton J

更新日期：2005-12-01 00:00:00

abstract：:Diabetes Mellitus frankly increases the prevalence of sexual problems in men, mainly in the form of erectile dysfunctions. Its effects on sexual function of the diabetic women have been less objectively studied, due to cultural reasons and methodological difficulties. The different phases of the sexual cycle, as well ...

journal_title：Diabetes & metabolism

authors： Buvat J,Lemaire A

更新日期：2001-09-01 00:00:00

abstract：AIMS:The objective of the present investigation was to study the production of IL-1, IL-6, IL-10, IFNgamma and TNFalpha in cultures of peripheral blood mononuclear cells (PBMC) taken from type 1 diabetic patients with inadequate metabolic control. METHODS:Seventeen type 1 diabetic patients and a gender- and age-matche...

journal_title：Diabetes & metabolism

authors： Foss NT,Foss-Freitas MC,Ferreira MA,Cardili RN,Barbosa CM,Foss MC

更新日期：2007-12-01 00:00:00