Patients' vehicle preference for corticosteroid treatments of scalp psoriasis.

abstract：:Superficial mycoses are becoming increasingly resistant to current antifungal medications. As alternative therapeutic options are limited, the increasing frequency of reports of antifungal resistance is alarming. This epidemic parallels the rise of antibiotic resistance; however, the significance of this problem has y...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Renaud HJ,Quinlan EM,Shear NH,Piguet V

更新日期：2020-12-22 00:00:00

abstract：:Most people in modern society are exposed daily to fragrance ingredients from one or more sources. Fragrance ingredients are also one of the most frequent causes of contact allergic reactions. The diagnosis is made by patch testing with a mixture of fragrance ingredients, the fragrance mix. This gives a positive patch...

journal_title：American journal of clinical dermatology

authors： Johansen JD

更新日期：2003-01-01 00:00:00

abstract：:Acne vulgaris is one of the most common inflammatory dermatoses and is seen in both the hospital setting and in general practice. Multiple factors are involved in the pathophysiology of acne, including: an alteration in the pattern of keratinization within the pilosebaceous follicles resulting in comedone formation; a...

journal_title：American journal of clinical dermatology

authors： Layton AM

更新日期：2001-01-01 00:00:00

abstract：:Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily that regulate lipid, glucose, and amino acid metabolism. More recently, PPARs and corresponding ligands have been shown in skin and other organs to regulate important cellular functions, including cell proliferation and...

journal_title：American journal of clinical dermatology

authors： Sertznig P,Seifert M,Tilgen W,Reichrath J

更新日期：2008-01-01 00:00:00

abstract：:Granular parakeratosis (GP) is a rare, idiopathic, and benign skin condition that presents classically as erythematous to brown hyperkeratotic papules that can coalesce into plaques. Axillary GP was initially observed by Northcutt and colleagues and has since been described in various other areas of the body including...

journal_title：American journal of clinical dermatology

authors： Ding CY,Liu H,Khachemoune A

更新日期：2015-12-01 00:00:00

abstract：:Tildrakizumab (tildrakizumab-asmn in the USA) [Ilumetri®; Ilumya™] is a humanized monoclonal antibody (mAb) that selectively targets the p19 subunit of interleukin (IL)-23, thereby inhibiting the IL-23/IL-17 axis, the signalling pathway primarily implicated in the immunopathogenesis of psoriasis. Administered subcutan...

journal_title：American journal of clinical dermatology

authors： Frampton JE

更新日期：2019-04-01 00:00:00

abstract：SIGNIFICANCE:Psoriasis, a common immune-mediated disease, affects approximately 2% of the population worldwide. Sudden sensorineural hearing loss (SSNHL) might be a manifestation of systemic vascular involvement in autoimmune disease. However, to the best of our knowledge, there is no systematic English-language examin...

journal_title：American journal of clinical dermatology

authors： Yen YC,Lin YS,Weng SF,Lai FJ

更新日期：2015-06-01 00:00:00

abstract：:Chronic itch is a common skin manifestation in many connective tissue diseases. However, the cause of chronic itch in these diseases is still not fully understood. The complex, and in some cases incomplete understanding of, pathogenesis in each condition makes it difficult to target specific mediators of chronic itch....

journal_title：American journal of clinical dermatology

authors： Haber JS,Valdes-Rodriguez R,Yosipovitch G

更新日期：2016-10-01 00:00:00

abstract：:The family of toll-like receptors (TLRs) plays a central role in the cutaneous immune defense system. To date, different TLRs have been found on several major cell populations of the skin, such as keratinocytes, fibroblasts, antigen-presenting cells, and melanocytes. Activation of TLRs leads, via different intracellul...

journal_title：American journal of clinical dermatology

authors： Terhorst D,Kalali BN,Ollert M,Ring J,Mempel M

更新日期：2010-01-01 00:00:00

abstract：:Darier's disease is a rare cutaneous disease with an autosomal dominant mode of inheritance. Greasy papules and plaques arise on the seborrheic areas and in the flexures and almost all patients have nail abnormalities. Acantholysis and dyskeratosis are the typical histological findings. The underlying defect is a resu...

journal_title：American journal of clinical dermatology

authors： Cooper SM,Burge SM

更新日期：2003-01-01 00:00:00

abstract：:Keratosis follicularis spinulosa decalvans is a rare, X-linked disorder characterized by scarring alopecia of the scalp and eyebrows in the setting of widespread keratosis pilaris. Less frequent associations are ocular abnormalities and palmoplantar keratoderma. Acne keloidalis nuchae has previously been described in ...

journal_title：American journal of clinical dermatology

authors： Janjua SA,Iftikhar N,Pastar Z,Hosler GA

更新日期：2008-01-01 00:00:00

abstract：:Black hairy tongue (BHT) is a benign condition commonly found among people who smoke, have poor oral hygiene, are immunocompromised, or have a medical condition limiting their ability to practice good oral hygiene. Though this condition is harmless, patients need to be educated on etiology as many common medications a...

journal_title：American journal of clinical dermatology

authors： Schlager E,St Claire C,Ashack K,Khachemoune A

更新日期：2017-08-01 00:00:00

abstract：:The connection between the brain and the skin is more than a physiologic fact. Skin conditions can impose great effects on every field in the patients' lives. Reciprocally, skin diseases can be evoked by psychological problems. A psychodermatology clinic is the format that enables dermatology patients to receive a com...

journal_title：American journal of clinical dermatology

authors： Orion E,Feldman B,Ronni W,Orit BA

更新日期：2012-04-01 00:00:00

abstract：:Seborrheic dermatitis (SD) is characterized by erythematous pruritic patches and plaques with greasy scale that occur in sebaceous areas. It is common, affecting up to 3% of the population. Past treatments have relied on a wide variety of anti-inflammatory and antifungal agents, but corticosteroids have limited use be...

journal_title：American journal of clinical dermatology

authors： Cook BA,Warshaw EM

更新日期：2009-01-01 00:00:00

abstract：:Disorders of cornification are a group of diseases that share abnormalities in the manufacture or desquamation of corneocytes. This paper reviews the major and a few of the rarer ones with a concentration on their therapy. Ichthyosis vulgaris is probably a post-translational defect in pro-filaggrin expression. It show...

journal_title：American journal of clinical dermatology

authors： Shwayder T

更新日期：2004-01-01 00:00:00

abstract：:Melanoma is a malignancy of pigment-producing cells that is driven by a variety of genetic mutations and aberrations. In most cases, this leads to upregulation of the mitogen-activated protein kinase (MAPK) pathway through activating mutations of upstream mediators of the pathway including BRAF and NRAS. With the adve...

journal_title：American journal of clinical dermatology

authors： Akabane H,Sullivan RJ

更新日期：2016-02-01 00:00:00

abstract：:After a marked decline in the number of syphilis cases in the context of AIDS prevention campaigns, a significant increase has been observed in states of the former Soviet Union since 1994. In recent years, outbreaks have also been reported in the US, Canada, and several European countries. The current epidemic in the...

journal_title：American journal of clinical dermatology

authors： Lautenschlager S

更新日期：2006-01-01 00:00:00

abstract：:At least 20 clinically relevant factors affect percutaneous absorption of drugs and chemicals: relevant physico-chemical properties, vehicle/formulation, drug exposure conditions (dose, duration, surface area, exposure frequency), skin appendages (hair follicles, glands) as sub-anatomical pathways, skin application si...

journal_title：American journal of clinical dermatology

authors： Law RM,Ngo MA,Maibach HI

更新日期：2020-02-01 00:00:00

abstract：:Tumor therapy is not a common indication for the use of lasers, as it is in the treatment of benign vascular skin lesions, since many alternative treatment modalities exist. However, certain patients may benefit from laser therapy of premalignant and malignant skin tumors. Skin tumors can be treated by laser excision,...

journal_title：American journal of clinical dermatology

authors： Karrer S,Szeimies RM,Hohenleutner U,Landthaler M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Evidence regarding what comprises effective education for acne vulgaris patients is lacking. Internet-based education may improve patient knowledge of this condition. OBJECTIVES:Our objective was to compare the effectiveness of standard web-based education and an automated counseling website in improving ac...

journal_title：American journal of clinical dermatology

authors： Tuong W,Wang AS,Armstrong AW

更新日期：2015-02-01 00:00:00

abstract：:Vitamin D plays a key role in skeletal and cardiovascular disorders, cancers, central nervous system diseases, reproductive diseases, infections, and autoimmune and dermatological disorders. The two main sources of vitamin D are sun exposure and oral intake, including vitamin D supplementation and dietary intake. Mult...

journal_title：American journal of clinical dermatology

authors： Kechichian E,Ezzedine K

更新日期：2018-04-01 00:00:00

abstract：:Erythema annulare centrifugum is a reactive erythema of various possible etiologies including, although less often, an associated cancer. Cancer-related erythema annulare centrifugum is most commonly associated with lymphoproliferative malignancies, specifically lymphoma and leukemia. Malignancy-associated erythema an...

journal_title：American journal of clinical dermatology

authors： Chodkiewicz HM,Cohen PR

更新日期：2012-08-01 00:00:00

abstract：:Coccidioidomycosis is an endemic mycosis of the southern United States, Northern Mexico, and South America. Primary cutaneous coccidioidomycosis, despite being a very rare clinical presentation, has shown an increasing incidence. An extensive literature search for cutaneous coccidioidomycosis cases was performed using...

journal_title：American journal of clinical dermatology

authors： Reyna-Rodríguez IL,Ocampo-Candiani J,Chavez-Alvarez S

更新日期：2020-10-01 00:00:00

abstract：:Mycobacterial organisms have re-emerged as an important cause of infectious disease worldwide. Both tuberculosis and nontuberculous mycobacterial infections remain endemic in many parts of the world and are becoming more common in patients with iatrogenic immunosuppression and HIV infection. The nontuberculous mycobac...

journal_title：American journal of clinical dermatology

authors： Elston D

更新日期：2009-01-01 00:00:00

abstract：:Rituximab is a chimeric monoclonal antibody that selectively binds to the CD20 molecule on B cells, resulting in their lysis. In autoimmune blistering diseases, the auto-antibody-producing B cells are destroyed and auto-antibody levels are reduced or eliminated. In the majority of patients, rituximab produces rapid cl...

journal_title：American journal of clinical dermatology

authors： Ahmed AR,Shetty S

更新日期：2015-06-01 00:00:00

abstract：:Topical pimecrolimus 1% cream (Elidel) [hereafter referred to as topical pimecrolimus] is a nonsteroidal alternative in the treatment of pediatric atopic dermatitis. In vehicle-controlled, short-term, continuous-use trials in pediatric patients with mild to moderate atopic dermatitis, topical pimecrolimus was effectiv...

journal_title：American journal of clinical dermatology

authors： Yang LP,Curran MP

更新日期：2010-01-01 00:00:00

abstract：:Viral skin infections are common findings in organ transplant recipients. The most important etiological agents are the group of human herpesviruses (HHV), human papillomaviruses (HPV), and molluscum contagiosum virus. HHV that are important in this group of patients are herpes simplex virus (HSV) types 1 and 2, varic...

journal_title：American journal of clinical dermatology

authors： Tan HH,Goh CL

更新日期：2006-01-01 00:00:00

abstract：:Tumor necrosis factor (TNF)-α inhibitors are an alternative to oral systemic therapies for psoriasis. Data regarding the safety of TNF-α inhibitors from randomized clinical trials may not fully reflect the effects on the clinic patient population receiving the therapy, but other sources of information are available. W...

journal_title：American journal of clinical dermatology

authors： Semble AL,Davis SA,Feldman SR

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:A few studies in psoriasis vulgaris patients have reported changes suggesting red blood cell (RBC) damage is linked to neutrophil activation, oxidative stress, and psoriasis worsening. OBJECTIVE:The aim of this study was to evaluate erythroid disturbances in Portuguese psoriasis vulgaris patients, before, d...

journal_title：American journal of clinical dermatology

authors： Coimbra S,Oliveira H,Reis F,Belo L,Rocha S,Quintanilha A,Figueiredo A,Teixeira F,Castro E,Rocha-Pereira P,Santos-Silva A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Methotrexate (MTX) is an effective treatment for psoriasis but its use is limited by its toxicity. Folate supplementation can be used to reduce the adverse effects of MTX, though this may impact efficacy. The frequency of folic acid supplementation is not well characterized. PURPOSE:The objective of this st...

journal_title：American journal of clinical dermatology

authors： Al-Dabagh A,Davis SA,Kinney MA,Huang K,Feldman SR

更新日期：2013-06-01 00:00:00