Primary hepatic neuroendocrine carcinoma coexisting with hepatocellular carcinoma in hepatitis C liver cirrhosis: report of a case.

Abstract:

:Primary hepatic neuroendocrine carcinoma is an extremely rare tumor of the liver. We herein describe a case of primary hepatic neuroendocrine carcinoma with lymph node metastases, coexisting with hepatocellular carcinoma, on a background of hepatitis C cirrrhosis, in a 72-year-old man. Abdominal ultrasonography and computed tomography (CT) showed a tumor (3 cm in diameter) in Couinaud's hepatic segment 8 (S8) with regional lymph node metastases. Whole-body CT, magnetic resonance imaging (MRI), and endoscopy did not reveal primary lesions outside the liver. Feridex MRI and [(18)F]fluorodeoxyglucose positron emission tomography were strongly suspicious of malignancy. A limited hepatectomy with regional lymph node dissection was performed. Histopathology, immunohistochemistry, and electron microscopy confirmed a diagnosis of primary neuroendocrine carcinoma on a background of liver cirrhosis. A tumor (1.5 cm in diameter) found in hepatic S5 at operation was also simultaneously resected, and histologically diagnosed to be hepatocellular carcinoma. We also review previous reports of hepatic neuroendocrine carcinoma and discuss hypotheses for the histogenesis of these tumors as well as prognostic implications. Given the background cirrhosis and coexisting hepatocellular carcinoma, we speculate that one of the hepatocellular carcinomas underwent neuroendocrine differentiation.

journal_name

Surg Today

journal_title

Surgery today

authors

Ishida M,Seki K,Tatsuzawa A,Katayama K,Hirose K,Azuma T,Imamura Y,Abraham A,Yamaguchi A

doi

10.1007/s005950300048

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

214-8

issue

3

eissn

0941-1291

issn

1436-2813

journal_volume

33

pub_type

杂志文章,评审
  • FoundationOne® CDx gene profiling in Japanese pancreatic ductal adenocarcinoma patients: a single-institution experience.

    abstract:PURPOSE:The aim of this study was to investigate the genetic mutation profiles of Japanese pancreatic ductal adenocarcinoma (PDAC) patients. METHODS:Next-generation sequencing was performed using FoundationOne® CDx on 17 PDAC patients who were treated by surgical resection at Kyushu University Hospital between Februar...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-020-02123-2

    authors: Kimura R,Ohtsuka T,Kubo M,Kajihara A,Fujii A,Watanabe Y,Mori Y,Ikenaga N,Nakata K,Shindo K,Ohuchida K,Nakamura M

    更新日期:2020-09-04 00:00:00

  • Preservation of physiological passage through the remnant stomach prevents postoperative malnutrition after proximal gastrectomy with double tract reconstruction.

    abstract:PURPOSE:Double tract reconstruction (DT) after proximal gastrectomy (PG) is considered beneficial for postoperative nutrition status by preserving the physiological passage of food. We conducted this study to assess postoperative nutrition status based on food passage after this operation. METHODS:The subjects of this...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-019-01799-5

    authors: Yamashita K,Iwatsuki M,Koga Y,Toihata T,Kiyozumi Y,Kuroda D,Eto K,Hiyoshi Y,Iwagami S,Baba Y,Miyamoto Y,Yoshida N,Baba H

    更新日期:2019-09-01 00:00:00

  • Arterial blood gas analysis in acute caustic ingestion injuries.

    abstract:PURPOSE:Quickly differentiating patients who need emergency salvage operation for caustic ingestion injury from those who do not remains difficult. We thus conducted a retrospective study to assess whether arterial blood gas (ABG) analysis is helpful for deciding on the best management plan. METHODS:We divided 129 pat...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s10595-002-2523-y

    authors: Cheng YJ,Kao EL

    更新日期:2003-01-01 00:00:00

  • Successful treatment of an esophageal hemangioma by endoscopic injection sclerotherapy: report of a case.

    abstract::We report herein the case of a 46-year-old man in whom an esophageal hemangioma was successfully treated by endoscopic injection sclerotherapy (EIS). The patient was admitted to hospital after a routine upper gastrointestinal series demonstrated a filling defect in the esophagus. Endoscopy, computed tomography (CT) im...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02385711

    authors: Aoki T,Okagawa K,Uemura Y,Nishioka K,Miyata H,Ukei T,Miyauchi K,Terashima T,Kaneko T,Mizunoya S

    更新日期:1997-01-01 00:00:00

  • A comparison of the results of prospective and retrospective cohort studies in the field of digestive surgery.

    abstract:PURPOSE:We compared the results of prospective and retrospective cohort studies in the field of digestive surgery to clarify whether the results of prospective cohort studies were more similar to those of randomized controlled trials (RCTs). METHODS:We conducted a secondary analysis of the results to compare the resul...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-017-1479-9

    authors: Ukai T,Shikata S,Nakayama T,Takemura YC

    更新日期:2017-07-01 00:00:00

  • Factors related to impaired bactericidal activity in patients with esophageal cancer.

    abstract::We examined the possible factors that could contribute to the impairment of polymorphonuclear neutrophil (PMN) bactericidal activities in patients with esophageal cancer, based on the discovery that a depression of the intracellular killing (KI) activity, with an elevation of the superoxide anion-producing capacity (S...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311251

    authors: Shigemitsu Y,Saito T,Kinoshita T,Katsuta T,Shimoda K,Kobayashi M

    更新日期:1995-01-01 00:00:00

  • Complete dissection of the lymph nodes located along and at the roots of the left gastroepiploic vessels during distal gastrectomy.

    abstract::Achieving complete dissection of the lymph nodes located at the roots of the left gastroepiploic vessels is difficult when distal gastrectomy is the surgical goal; firstly, because the short gastric vessels must be preserved to supply blood to the remnant stomach; and also, because the roots of the left gastroepiploic...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950050320

    authors: Seto Y,Nagawa H,Kaizaki S,Nakayama H,Muto T

    更新日期:1998-01-01 00:00:00

  • Modified neutrophil-platelet score as a promising marker for stratified surgical and oncological outcomes of patients with gastric cancer.

    abstract:PURPOSE:Gastric cancer (GC) is a common malignancy, especially in East Asian countries. There is emerging evidence that circulating neutrophil and platelet levels correlate with cancer progression. We evaluated the short- and long-term outcomes of GC patients systemically, to compare the original neutrophil-platelet sc...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-019-01873-y

    authors: Okugawa Y,Toiyama Y,Yamamoto A,Omura Y,Kusunoki K,Yin C,Ide S,Kitajima T,Koike Y,Fujikawa H,Yasuda H,Okita Y,Hiro J,Yoshiyama S,Ohi M,Araki T,Kusunoki M

    更新日期:2020-03-01 00:00:00

  • Impact of microvessel density on lymph node metastasis and survival after curative resection of pancreatic cancer.

    abstract:PURPOSE:The roles of angiogenesis and the most prominent angiogenic vascular endothelial growth factor (VEGF) in diseases of the pancreas remain controversial. We compared microvessel density (MVD) and VEGF status in normal pancreatic, chronic pancreatic, and pancreatic cancer (PC) tissues to establish their prognostic...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-011-0045-0

    authors: Benckert C,Thelen A,Cramer T,Weichert W,Gaebelein G,Gessner R,Jonas S

    更新日期:2012-01-01 00:00:00

  • Laparoscopic excision of a retroperitoneal cystic lymphangioma: report of a case.

    abstract::A 36-year-old woman without any relevant medical history was admitted to our hospital with an abdominal tumor that had caused recurrent right hypochondral and back pain for 3 months. Retroperitoneal cystic lymphangioma was diagnosed by abdominal ultrasonography and computed tomography. We suc-cessfully excised the tum...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950300032

    authors: Tsukamoto T,Tanaka S,Yamamoto T,Kakinoki E,Uemichi A,Kubo S,Hirohashi K,Kinoshita H

    更新日期:2003-01-01 00:00:00

  • Reinforced mitral valve replacement using a xenopericardium collared prosthetic valve for a heavily calcified or disrupted mitral annulus: a simple "Dumpling technique".

    abstract::Heavy mitral annular calcification or severe destruction of the mitral annulus in the setting of mitral valve replacement may result in fatal complications, such as atrioventricular disruption, ventricular rupture, valve dehiscence, and perivalvular leakage. Collar-reinforced mitral valve replacements with xenopericar...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-016-1447-9

    authors: Ishida M,Toda K,Nakamura T,Miyagawa S,Yoshikawa Y,Fukushima S,Saito S,Ueno T,Kuratani T,Sawa Y

    更新日期:2017-07-01 00:00:00

  • A new method of performing continuous intraabdominal drainage after pancreaticoduodenectomy.

    abstract::Dehiscence of the pancreaticoenterostomy is one of the most feared, yet common, postoperative complications following pancreaticoduodenectomy (PD). We report herein a new technique we developed for performing continuous intraabdominal suction drainage (CISD) following PD. This method of CISD involves positioning an 18...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF00311482

    authors: Kayahara M,Nagakawa T,Ueno K,Ohta T,Miyazaki I

    更新日期:1995-01-01 00:00:00

  • Salvage lymphadenectomy of the right recurrent nerve node with tracheal involvement after definitive chemoradiation therapy for esophageal squamous cell carcinoma: report of two cases.

    abstract::Thoracic esophageal cancers frequently metastasize to the right recurrent nerve nodes (RRNNs). In fact, huge RRNNs invading the trachea sometimes remain after definitive chemoradiation therapy (CRT), despite complete remission of the primary lesion. We performed salvage lymphadenectomy of a large RRNN combined with pa...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3447-7

    authors: Doki Y,Yasuda T,Miyata H,Fujiwara Y,Takiguchi S,Yamasaki M,Makari Y,Matsuyama J,Masuoka T,Monden M

    更新日期:2007-01-01 00:00:00

  • Solitary cavernous hemangioma of the duodenum: report of a case.

    abstract::Vascular lesions of the duodenum, including hemangioma, are rare causes of gastrointestinal bleeding. We herein describe a 52-year-old woman with a solitary cavernous hemangioma of the duodenum that caused chronic gastrointestinal bleeding. Repeated upper gastrointestinal endoscopy and a barium meal study revealed a s...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311641

    authors: Fujikawa T,Kurata M,Takaori K,Matsusue S,Takeda H,Sakai S

    更新日期:1996-01-01 00:00:00

  • Receiver-operating characteristic analysis of leukocyte counts and serum C-reactive protein levels in children with advanced appendicitis.

    abstract:PURPOSE:To assess the diagnostic value of the white blood cell count (WBC) and serum C-reactive protein (CRP) level in children with advanced appendicitis. METHODS:We reviewed 289 children ranging in age from 3 to 15 years old, who underwent appendectomy in our hospital between 1993 and 2003. The advanced appendicitis...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3189-6

    authors: Okamoto T,Sano K,Ogasahara K

    更新日期:2006-01-01 00:00:00

  • Predictors of hypocalcemia occurring after a total/near total thyroidectomy.

    abstract:PURPOSE:The aim of this study was to identify the predictors of early postoperative hypocalcemia after a total/near total thyroidectomy in order to select patients for prompt treatment to prevent symptomatic hypocalcemia. METHODS:Patients with hypocalcemia within 24 h of surgery were identified as Group I and normocal...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00595-009-3957-1

    authors: Kara M,Tellioglu G,Krand O,Fersahoglu T,Berber I,Erdogdu E,Ozel L,Titiz MI

    更新日期:2009-01-01 00:00:00

  • The dynamics and clinical significance of alpha 2 plasmin inhibitor-plasmin complex and thrombin-antithrombin complex in postoperative pleural effusion following a pulmonary lobectomy.

    abstract:PURPOSE:The overall incidence of postoperative alveolar air leakage (AAL) remains high; however, the mechanism regarding how to adequately heal such postoperative AAL remains to be elucidated. The aim of this study was to determine any correlations between the activity of the fibrinolytic and coagulation system in the ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3865-9

    authors: Shoji F,Yano T,Yoshino I,Kawano D,Takenaka T,Miura N,Ito K,Morodomi Y,Maehara Y

    更新日期:2009-01-01 00:00:00

  • The enhanced therapeutic efficacy of intra-arterial cis-diamminedichloroplatinum (II) chemotherapy in combination with aortic clamping on metastatic hepatic tumors in the rat.

    abstract::The efficacy of intrahepatic cis-diamminedichloroplatinum (II), cisplatin, administered via the hepatic artery in combination with concomitant clamping of the abdominal aorta beneath the diaphragm against metastatic liver tumors in rats was evaluated. When 2.5 or 5 mg/kg of cisplatin was injected intra-arterially (i.a...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02473393

    authors: Nishioka Y

    更新日期:1994-01-01 00:00:00

  • Ano-urethral fistula, a special type of anomaly: report of two cases.

    abstract::Two cases of an ano-urethral fistula, being a low malformation, are reported herein. Both patients underwent a colostomy under the diagnosis of a recto-urethral fistula during the neonatal period. As a urethro-rectogram later revealed the fistula to be located between the anus and anterior urethra, revision of the ure...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00309106

    authors: Takamatsu H,Noguchi H,Tahara H,Kajiya H,Kaji T,Ikee T,Yoshioka T,Akiyama H

    更新日期:1993-01-01 00:00:00

  • The development of a small bowel volvulus in the early postoperative period following a distal gastrectomy: report of a case.

    abstract::A 51-year-old Japanese man who underwent a standard distal gastrectomy for cancer of the stomach developed abdominal pain when oral intake was commenced on the 6th postoperative day after an uneventful postoperative course. Complete obstruction of the jejunum led to a sudden deterioration in his general condition and ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF01367459

    authors: Sakamoto T,Miyata M,Nakamuro M,Izukura M,Kamiike W,Matsuda H

    更新日期:1994-01-01 00:00:00

  • Dedifferentiation of neoplastic cells in medullary thyroid carcinoma: report of a case.

    abstract::We report herein the unusual case of a man who was diagnosed as having sporadic medullary thyroid carcinoma (MTC) at the age of 29 years, and subsequently followed up for a period of 18 years. A total thyroidectomy with radical neck dissection was initially performed, followed by a stable interval of 16 years with reg...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02482271

    authors: Osaka M,Soga J,Tamiya Y,Suzuki T

    更新日期:1999-01-01 00:00:00

  • The association of cigarette smoking with a high risk of recurrence after ileocolonic resection for ileocecal Crohn's disease.

    abstract::The purpose of this retrospective study was to examine the influence of cigarette smoking on the recurrence of Crohn's disease after resection. Between 1975 and 1990, 141 patients underwent primary ileocolonic resection for ileocecal Crohn's disease, 79 of whom were nonsmokers and 62 of whom were smokers at the time o...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02482360

    authors: Yamamoto T,Keighley MR

    更新日期:1999-01-01 00:00:00

  • Possible roles of 5-HT in vein graft failure due to intimal hyperplasia 5-HT, nitric oxide and vein graft.

    abstract::For vascular occlusive disease, an autologous vein graft is the most suitable conduit for arterial reconstruction. Intimal hyperplasia, resulting from the migration and proliferation of vascular smooth muscle cells, is a major obstacle to patency after vein grafting. The degree to which the function of nitric oxide (N...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-013-0555-z

    authors: Kodama A,Itoh T,Komori K

    更新日期:2014-02-01 00:00:00

  • Does potassium ion concentration affect lung preservation?

    abstract::To evaluate the influence of potassium ion concentration in an organ preservation solution on lung preservation, four types of solutions were produced. These preservation solutions consisted of sodium and potassium ions on the cation and phosphate ions on the anion with glucose. Contents of solutions were: (1) 155 mmo...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950050104

    authors: Ono K,Sone Y,Irie T,Ohnuki T,Nitta S

    更新日期:1998-01-01 00:00:00

  • Invasive micropapillary carcinoma of the ampulla of Vater with extensive lymph node metastasis: Report of a case.

    abstract::Invasive micropapillary carcinoma is characterized by extensive lymph node metastasis and a poor prognosis. This histological variant was first described in breast cancer, with a few subsequent reports of it in the ampullo-pancreato-biliary region. We report a case of invasive micropapillary carcinoma of the papilla o...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-010-4330-0

    authors: Fujita T,Konishi M,Gotohda N,Takahashi S,Nakagohri T,Kojima M,Kinoshita T

    更新日期:2010-12-01 00:00:00

  • Primary localized amyloidosis of the small intestine presenting as an intestinal pseudo-obstruction: report of a case.

    abstract::A 47-year-old man with primary amyloidosis confined to the small intestine is reported. Thickening of the folds and multiple polypoid protrusions were found in the duodenum by upper gastrointestinal endoscopy. Because the patient presented with a persistent intestinal pseudo-obstruction, partial jejunectomy was perfor...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/PL00022938

    authors: Deguchi M,Shiraki K,Okano H,Yamanaka T,Ito N,Takase K,Nakano T

    更新日期:2001-01-01 00:00:00

  • Adult neuroblastoma in pregnancy: report of a case.

    abstract::We report herein an extremely rare case of retroperitoneal neuroblastoma occurring in a mother during her third trimester of pregnancy. A live male infant was delivered by cesarean section at 36 weeks gestation and 23 days later, the mother's tumor was curatively resected. Six months have elapsed since her operation a...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311716

    authors: Ohashi K,Sawada H,Kanaizumi T,Nakano H,Okamoto S,Maruyama H,Tsutsumi M,Konishi Y

    更新日期:1993-01-01 00:00:00

  • Effect of imatinib (STI571) on metastatic gastrointestinal stromal tumors: report of a case.

    abstract::The prognosis for advanced gastrointestinal stromal tumor (GIST) is poor. However, recent reports from Europe have described the effects of imatinib against metastatic GIST. We herein report the case of a Japanese patient treated with imatinib for advanced GIST. Imatinib at 400 mg daily was given to an adult with mult...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-004-2890-6

    authors: Ando Y,Tsunoda T,Beck Y,Takayama T,Tahara H

    更新日期:2005-01-01 00:00:00

  • The successful application of jejunal interposition for severe dumping syndrome: report of a case.

    abstract::We report herein the case of a 76-year-old man with intractable dumping syndrome which had manifested itself 3 years after he underwent a gastric resection and Billroth I reconstruction for a gastric ulcer. Despite aggressive medical therapy by the time of admission, he had suffered from disabling dumping symptoms for...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF01651008

    authors: Ishikawa M,Morioka E,Wada D,Komi N

    更新日期:1994-01-01 00:00:00

  • Drug development for intraperitoneal chemotherapy against peritoneal carcinomatosis from gastrointestinal cancer.

    abstract::Intraperitoneal (IP) chemotherapy for peritoneal carcinomatosis (PC) from gastrointestinal cancer has been investigated and applied clinically for several decades. Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy have been considered to be the optimal treatment options for selected patients with co...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-014-0848-x

    authors: Emoto S,Sunami E,Yamaguchi H,Ishihara S,Kitayama J,Watanabe T

    更新日期:2014-12-01 00:00:00