Abstract:
:New analogues of the previously described 3-aryl pyridone KOR agonists have been synthesised by parallel synthetic methods, both in solution- and with solid-phase chemistry, making use of the well known and versatile Mitsunobu, Suzuki and Buchwald reactions. Opioid receptor binding data for the compounds produced is reported.
journal_name
Bioorg Med Chem Lettjournal_title
Bioorganic & medicinal chemistry lettersauthors
Semple G,Andersson BM,Chhajlani V,Georgsson J,Johansson MJ,Rosenquist A,Swanson Ldoi
10.1016/s0960-894x(03)00033-7subject
Has Abstractpub_date
2003-03-24 00:00:00pages
1141-5issue
6eissn
0960-894Xissn
1464-3405pii
S0960894X03000337journal_volume
13pub_type
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