Comparison of maximal midexpiratory flow rate and forced expiratory flow at 50% of vital capacity in children.

Abstract:

BACKGROUND:The mid-portion of the maximal expiratory flow-volume (MEFV) curve is often described by values of the mean forced expired flow as lung volume decreases from 75% to 25% of vital capacity (ie, forced expiratory flow, midexpiratory phase [FEF(25-75)]). It is common practice to report also forced expired flow at 50% of vital capacity (FEF(50)). STUDY OBJECTIVE:To investigate whether FEF(50) and FEF(25-75) are highly correlated or whether the difference between them reflects a degree of airways obstruction. Also, we wanted to investigate the correlation between the two in cases of irregularly shaped MEFV curves (ie, "saw-toothing"). DESIGN:Analysis of the correlation between FEF(50) and FEF(25-75) in a single determination. We assessed the relationship between the FEF(50)/FEF(25-75) ratio and the degree of airways obstruction, as reflected by other traditional parameters such as FEV(1), FEV(1)/FVC ratio, and specific airway conductance (SGaw). PATIENTS:There were 1,350 forced expiratory maneuvers performed by children with a broad range of pulmonary abnormalities. RESULTS:FEF(50) correlated with FEF(25-75) as follows: FEF(50) (L/s) = 0.041 + 1.136*FEF(25-75)(L/s); r(2) = 0.956; standard error of the estimate = 0.013; p < 0.0001. The FEF(50)/FEF(25-75) ratio remained stable and did not correlate with FEV(1) (r = 0.12), FEV(1)/FVC ratio (r = 0.11), or SGaw (r = 0.02; difference not significant). The correlation between FEF(25-75) and FEF(50) was similar for both the smooth curve (r = 0.97) and the irregular curve (r = 0.96). CONCLUSIONS:Although not identical, FEF(25-75) and FEF(50) are highly correlated, and the ratio of the two is fairly constant. Therefore, the practice of reporting both of them is unnecessary. We suggest that it is reasonable to prefer FEF(50).

journal_name

Chest

journal_title

Chest

authors

Bar-Yishay E,Amirav I,Goldberg S

doi

10.1378/chest.123.3.731

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

731-5

issue

3

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)34737-7

journal_volume

123

pub_type

杂志文章

相关文献

CHEST文献大全
  • Recurrent syncope for over a decade due to idiopathic ventricular fibrillation.

    abstract::A 35-year-old man had a history of recurrent syncope for more than a decade. During a witnessed episode, an ambulatory electrocardiographic recording showed ventricular flutter/fibrillation that lasted for 2 1/2 minutes and terminated spontaneously without adverse neurologic sequelae. No structural heart disease and n...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.106.5.1601

    authors: Masrani K,Cowley C,Bekheit S,el-Sherif N

    更新日期:1994-11-01 00:00:00

  • Prolonged myocardial ischemia after intravenous dipyridamole thallium imaging.

    abstract::Intravenous dipyridamole thallium imaging is reported to be a safe test with minimal side effects. It has been proposed by some that the test simply dilates the coronary vessels without actually producing myocardial ischemia. In this report, we describe a patient who, following intravenous dipyridamole thallium imagin...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.6.1102

    authors: Lewen MK,Labovitz AJ,Kern MJ,Chaitman BR

    更新日期:1987-12-01 00:00:00

  • Spinal cord ischemia resulting in paraplegia following extrapleural pneumonectomy.

    abstract::A patient undergoing radical extrapleural pneumonectomy for epithelioid malignant mesothelioma developed acute paraplegia postoperatively related to long-segment spinal cord ischemia. The usual area of concern for this complication is the T9 to T12 area where the artery of Adamkiewicz is most likely to originate. In t...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.13-3062

    authors: Ural K,Jakob K,Lato S,Gilly G,Landreneau R

    更新日期:2014-08-01 00:00:00

  • Predictors of survival in patients with chronic obstructive pulmonary disease treated with long-term oxygen therapy.

    abstract::Long-term oxygen is the only therapy that has been shown to improve survival in patients with chronic obstructive pulmonary disease. The aim of this study was to assess the predictors of survival in such patients treated with long-term oxygen therapy. We studied 179 patients who were assessed for long-term oxygen ther...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.6.1522

    authors: Skwarski K,MacNee W,Wraith PK,Sliwinski P,Zielinski J

    更新日期:1991-12-01 00:00:00

  • Left-to-right shunt via left superior vena cava communication with left atrium.

    abstract::The findings in a 22-year-old man with Ebstein's anomaly of the tricuspid valve, Wolff-Parkinson-White syndrome, and a persistent left superior vena cava are reported. This is the first reported case of this combination of anomalies in which the atrial septum was intact and the left superior vena cava communicated wit...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.79.6.700

    authors: Lam W,Danoviz J,Witham D,Wyndham C,Rosen KM

    更新日期:1981-06-01 00:00:00

  • Maximal exercise testing for the selection of heart transplantation candidates: limitation of peak oxygen consumption.

    abstract:BACKGROUND:Peak exercise oxygen consumption (peak VO2), which is considered an indicator of prognosis in advanced heart failure, is currently being used as a major criterion in many centers for the selection of candidates for heart transplantation. Available studies suggest that patients with peak VO2 < 14 mL/min/kg ha...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.2.410

    authors: Ramos-Barbón D,Fitchett D,Gibbons WJ,Latter DA,Levy RD

    更新日期:1999-02-01 00:00:00

  • Infectious complications following isolated lung transplantation.

    abstract:STUDY OBJECTIVE:To ascertain the incidence, types, morbidity, and mortality of infectious episodes in isolated lung transplant recipients. DESIGN:Retrospective chart review of patients who have undergone transplants over a six-year period in one institution. PATIENTS:Twenty-three single and 17 double lung transplants...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.4.1056

    authors: Maurer JR,Tullis DE,Grossman RF,Vellend H,Winton TL,Patterson GA

    更新日期:1992-04-01 00:00:00

  • Elevated concentrations of exhaled hydrogen peroxide in asthmatic patients.

    abstract:BACKGROUND:Airway inflammation is important in the development and progression of asthma. Activation of inflammatory cells induces a respiratory burst resulting in the production of reactive oxygen species, such as H(2)O(2). The aim of this study was to measure the concentration of H(2)O(2) in exhaled breath condensate...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.120.4.1136

    authors: Emelyanov A,Fedoseev G,Abulimity A,Rudinski K,Fedoulov A,Karabanov A,Barnes PJ

    更新日期:2001-10-01 00:00:00

  • Short- and long-term hemodynamic effects of captopril in patients with pulmonary hypertension and selected connective tissue disease.

    abstract::To assess the pulmonary and systemic hemodynamic effects of oral captopril in patients with connective tissue disease and pulmonary hypertension, we performed right heart catheterization in eight patients with diffuse systemic sclerosis, the CREST syndrome, or mixed connective tissue diseases prior to and immediately ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.5.1407

    authors: Alpert MA,Pressly TA,Mukerji V,Lambert CR,Mukerji B

    更新日期:1992-11-01 00:00:00

  • Tropical pulmonary eosinophilia.

    abstract::Tropical pulmonary eosinophilia (TPE) usually affects people living in the tropics, especially those in Southeast Asia, India, and certain parts of China and Africa. However, owing to the rising frequency of world-wide travel and the migration between continents, this disease is increasingly seen in the West, where th...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.113.6.1673

    authors: Ong RK,Doyle RL

    更新日期:1998-06-01 00:00:00

  • Improvement in pulmonary function in mitral stenosis after percutaneous transvenous mitral commissurotomy.

    abstract::Before and after percutaneous transvenous mitral commissurotomy (PTMC), pulmonary function studies were performed in 25 patients with mitral stenosis, in order to determine the effects of pulmonary hemodynamics on pulmonary function in patients with mitral stenosis. After PTMC, dramatic improvements in pulmonary hemod...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.2.290

    authors: Yoshioka T,Nakanishi N,Okubo S,Kunieda T,Ishikura F,Nagata S

    更新日期:1990-08-01 00:00:00

  • Prevalence and prognostic value of left ventricular diastolic dysfunction in idiopathic and heritable pulmonary arterial hypertension.

    abstract:BACKGROUND:Little is known about the association between left ventricular (LV) diastolic dysfunction and outcomes in patients with idiopathic or heritable pulmonary arterial hypertension (PAH). Our rationale was to investigate the prevalence of LV diastolic dysfunction, and its association with disease severity and out...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-1903

    authors: Tonelli AR,Plana JC,Heresi GA,Dweik RA

    更新日期:2012-06-01 00:00:00

  • Relationship of vancomycin minimum inhibitory concentration to mortality in patients with methicillin-resistant Staphylococcus aureus hospital-acquired, ventilator-associated, or health-care-associated pneumonia.

    abstract:BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and health-care-associated pneumonia (HCAP). These infections are associated with significant morbidity, mortality, and cost. The impact of vancomycin minimum inh...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.09-2453

    authors: Haque NZ,Zuniga LC,Peyrani P,Reyes K,Lamerato L,Moore CL,Patel S,Allen M,Peterson E,Wiemken T,Cano E,Mangino JE,Kett DH,Ramirez JA,Zervos MJ,Improving Medicine through Pathway Assessment of Critical Therapy of Hospital-Acqu

    更新日期:2010-12-01 00:00:00

  • Treatment failure in community-acquired pneumonia.

    abstract::Treatment failure (TF) is defined as a clinical condition with inadequate response to antimicrobial therapy. Clinical response should be evaluated within the first 72 h of treatment, whereas infiltrate images may take up to 6 weeks to resolve. Early failure is considered when ventilatory support and/or septic shock ap...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.06-1995

    authors: Menendez R,Torres A

    更新日期:2007-10-01 00:00:00

  • CPR and postarrest care: overview, documentation, and databases.

    abstract::It is estimated that 350,000 people suffer a cardiac arrest each year in the United States, with one-half occurring out-of-hospital and the other half in-hospital. Overall survival is < 10% and has not changed significantly for decades. CPR is the umbrella term for attempts to restore organized cardiac contractility a...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.11-2130

    authors: Gaieski DF,Abella BS,Goyal M

    更新日期:2012-04-01 00:00:00

  • High rhinovirus burden in lower airways of children with cystic fibrosis.

    abstract:BACKGROUND:Rhinovirus (RV)-induced pulmonary exacerbations are common in cystic fibrosis (CF) and have been associated with impaired virus clearance by the CF airway epithelium in vitro. Here, we assess in vivo the association of RV prevalence and load with antiviral defense mechanisms, airway inflammation, and lung fu...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-0954

    authors: Kieninger E,Singer F,Tapparel C,Alves MP,Latzin P,Tan HL,Bossley C,Casaulta C,Bush A,Davies JC,Kaiser L,Regamey N

    更新日期:2013-03-01 00:00:00

  • Therapeutic potential of mesenchymal stem cells for severe acute lung injury.

    abstract::Preclinical studies indicate that allogeneic human mesenchymal stem cells (MSC) may be useful for the treatment of several clinical disorders, including sepsis, acute renal failure, acute myocardial infarction, and more recently, acute lung injury (ALI). This article provides a brief review of the biologic qualities o...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.10-0518

    authors: Matthay MA,Thompson BT,Read EJ,McKenna DH Jr,Liu KD,Calfee CS,Lee JW

    更新日期:2010-10-01 00:00:00

  • Sarcoidosis Diagnostic Score: A Systematic Evaluation to Enhance the Diagnosis of Sarcoidosis.

    abstract:BACKGROUND:The diagnosis of sarcoidosis is made by the combination of clinical features and biopsy results. The clinical features of sarcoidosis can be quite variable. We developed a Sarcoidosis Diagnostic Score (SDS) to summarize the clinical features of patients with possible sarcoidosis. METHODS:Biopsy-confirmed pa...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2018.05.003

    authors: Bickett AN,Lower EE,Baughman RP

    更新日期:2018-11-01 00:00:00

  • Clonidine in the elderly hypertensive. Monotherapy and therapy with a diuretic.

    abstract::Forty-eight elderly patients with uncomplicated mild essential hypertension entered two drug regimens. In group 1, clonidine monotherapy (n = 15), clonidine was titrated to achieve goal blood pressure (less than 90 mm Hg diastolic) in dosages of 0.05 mg twice daily to 0.2 mg three times daily. Blood pressure decreased...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.83.2.410

    authors: Thananopavarn C,Golub MS,Sambhi MP

    更新日期:1983-02-01 00:00:00

  • Preflight medical screenings of patients. Analysis of health and flight characteristics.

    abstract::We evaluated the demographic, medical, and flight characteristics of 1,115 passengers who were routinely referred for preflight medical screening by a major domestic air carrier. The largest category consisted of 892 patients who requested in-flight oxygen therapy for cardiopulmonary conditions, of which COPD and card...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.3.788

    authors: Gong H Jr,Mark JA,Cowan MN

    更新日期:1993-09-01 00:00:00

  • A 62-Year-Old Woman With Wheezing, Respiratory Failure, and an Abnormal CT Scan.

    abstract:CASE PRESENTATION:A previously healthy 62-year-old woman was transferred to the ICU from the medical ward with acute bronchospastic respiratory failure requiring intubation and mechanical ventilation. Four weeks before, the patient was vacationing in Arizona and acquired a mildly productive cough as well as mild dyspne...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2017.04.168

    authors: Hountras P,Cajigas H

    更新日期:2017-09-01 00:00:00

  • An Audit of medical thoracoscopy and talc poudrage for pneumothorax prevention in advanced COPD.

    abstract:OBJECTIVES:To prospectively study all patients with COPD and spontaneous pneumothorax (SP) who underwent thoracoscopic talc poudrage (TP) under local anesthesia to determine its efficacy and safety in recurrence prevention. METHODS:Data on clinical measurements, complications, duration of chest tube drainage, length o...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.125.4.1315

    authors: Lee P,Yap WS,Pek WY,Ng AW

    更新日期:2004-04-01 00:00:00

  • Detection of MALT1 gene rearrangements in BAL fluid cells for the diagnosis of pulmonary mucosa-associated lymphoid tissue lymphoma.

    abstract:BACKGROUND:Mucosa-associated lymphoid tissue (MALT) lymphoma constitutes approximately 90% of primary pulmonary lymphoma, and the diagnosis of pulmonary MALT lymphoma often requires invasive methods such as surgical lung biopsy. Chromosomal rearrangements involving MALT lymphoma translocation gene 1 (MALT1) have been r...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-0068

    authors: Kido T,Yatera K,Noguchi S,Sakurai Y,Nagata S,Kozaki M,Tokuyama S,Ogoshi T,Kawanami T,Yoshii C,Mukae H

    更新日期:2012-01-01 00:00:00

  • Automatic objective diagnosis of lymph nodal disease by B-mode images from convex-type echobronchoscopy.

    abstract:BACKGROUND:We investigated whether artificial neural networks (ANNs) could diagnose pathology of lymph nodes by feeding B-mode images from convex-type echobronchoscopy to ANNs. METHODS:Subjects comprised 91 patients who had undergone endobronchial ultrasonography transbronchial needle aspiration at our hospital betwee...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.07-1497

    authors: Tagaya R,Kurimoto N,Osada H,Kobayashi A

    更新日期:2008-01-01 00:00:00

  • Melioidosis complicated by pericarditis.

    abstract::A case of acute and recrudescent melioidosis complicated by pericarditis and pericardial effusion is described. The potential for the appearance of future cases in the United States and the necessity for physicians to remain aware of this potential diagnosis are discussed. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.69.2.227

    authors: Ruff MJ,Lamkin N Jr,Braun J,Barnwell P

    更新日期:1976-02-01 00:00:00

  • Outcomes of Nurse Practitioner-Delivered Critical Care: A Prospective Cohort Study.

    abstract:BACKGROUND:Acute care nurse practitioners (ACNPs) are increasingly being employed in ICUs to offset physician shortages, but no data exist about outcomes of critically ill patients continuously cared for by ACNPs. METHODS:Prospective cohort study of all admissions to an adult medical ICU in an academic, tertiary-care ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2015.12.015

    authors: Landsperger JS,Semler MW,Wang L,Byrne DW,Wheeler AP

    更新日期:2016-05-01 00:00:00

  • Congenital atrioventricular block in right atrial isomerism (asplenia). A case due to atrionodal discontinuity.

    abstract::The association of complex congenital heart disease with asplenia syndrome and congenital AV block is described in a newborn. Cardiovascular lesions were right atrial isomerism, d-loop, discordant ventriculoarterial connection, pulmonary stenosis, total anomalous pulmonary venous drainage, absent right pulmonary arter...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.85.4.578

    authors: Rossi L,Montella S,Frescura C,Thiene G

    更新日期:1984-04-01 00:00:00

  • Bronchoalveolar lavage-induced pneumothorax.

    abstract::Bronchoalveolar lavage (BAL) has not been associated with the complication of pneumothorax. Candidates for this procedure are predisposed to develop pneumothorax due to underlying infectious interstitial emphysema. This risk factor is increased by the hyperbaric consequences of lavage and also by the cough induced by ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.94.2.440

    authors: Krueger JJ,Sayre VA,Karetzky MS

    更新日期:1988-08-01 00:00:00

  • Left lung asthma.

    abstract::The chest radiograph of a woman with acute asthma showed signs of obstructive emphysema of the left lung. Fiberoptic bronchoscopy excluded obstruction of a large bronchus. The signs disappeared after antiasthmatic treatment, suggesting that they were caused by airway closure. In usual asthma, airway closure affects bo...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.6.1919

    authors: DiFrancia M,Barbier D,Orehek J

    更新日期:1993-12-01 00:00:00

  • Influence of three factors on the diagnostic effectiveness of transthoracic needle aspiration in pneumonia.

    abstract::Prior antibiotic therapy, size of the infiltrate, and the person who performed the technique were the three factors that we studied to assess their influence on the effectiveness of transthoracic needle aspiration (TNA). Ninety-one patients with a diagnosis of severe bacterial pneumonia, who underwent TNA, have been i...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.1.96

    authors: Zalacain R,Llorente JL,Gaztelurrutia L,Pijoan JI,Sobradillo V

    更新日期:1995-01-01 00:00:00