Effects of growth hormone on testicular dysfunction induced by cyclophosphamide (CP) in GH-deficient rats.

abstract：:A 73-year-old Japanese woman was referred for examination of right flank pain and progressive hypertension. Abdominal CT incidentally detected a right adrenal mass 8 cm in size. The tumor exhibited isodensity by CT and contained high-intense lesion by T2-weighted MRI. Scintigraphy with (131) I-metaiodobenzylguanidine ...

journal_title：Endocrine journal

authors： Goto J,Otsuka F,Kodera R,Miyoshi T,Kinomura M,Otani H,Mimura Y,Ogura T,Yanai H,Nasu Y,Makino H

更新日期：2008-03-01 00:00:00

abstract：:The present study was aimed to examine the possible functional relationship between melatonin and hypothalamic transmitters, endogenous opioids and excitatory amino acids in controlling gonadotropin secretion in ovariectomized estrogen-primed rats. An intravenous injection of naloxone (mu opioid receptor antagonist), ...

journal_title：Endocrine journal

authors： Akema T,Ikeda T,Chiba A,Sugiyama H,Sato I,Kimura F,Toyoda J

更新日期：1999-12-01 00:00:00

abstract：:A 67-year-old female with hypertension and impaired glucose tolerance was admitted to our hospital because of a typical acromegalic appearance, including large, thickened bulky hands and feet, and a large prominent forehead and tongue. She did not have a Cushingoid appearance, such as a moon-face, buffalo hump, purple...

journal_title：Endocrine journal

authors： Kobayashi Y,Takei M,Ohkubo Y,Kakizawa Y,Matoba H,Kumagai M,Takeda T,Suzuki S,Komatsu M

更新日期：2014-01-01 00:00:00

abstract：:A patient with an apparently normal 46, XY karyotype, suffering from pure gonadal dysgenesis and of short stature was investigated. The patient, who was growth retarded, was a 30-year-old married Japanese woman with a history of primary amenorrhea and infertility with a weight of 42 kg and a height of 146 cm. She has ...

journal_title：Endocrine journal

authors： Tsutsumi O,Iida T,Taketani Y,Sugase M,Nakahori Y,Nakagome Y

更新日期：1994-06-01 00:00:00

abstract：:Pregnancy in acromegalic patients is a rare event, but is usually uneventful, with stable GH and IGF-I levels and no tumor enlargement. Medical treatment can usually be withdrawn without problems and although no major adverse event has been reported, the suspension of drug treatments is generally recommended. No cas...

journal_title：Endocrine journal

authors： Kasuki L,Neto LV,Takiya CM,Gadelha MR

更新日期：2012-01-01 00:00:00

abstract：:A fasting triglyceridemia >10 mmol/L is associated with chylomicronemia (CM) and an increased recurrent acute pancreatitis (RAP) risk. The number of pancreatitis episodes varies significantly between patients with CM. The objective of this study was to investigate gene expression profiles of RAP in patients with CM. A...

journal_title：Endocrine journal

authors： Tremblay K,Brisson D,Gaudet D

更新日期：2020-11-28 00:00:00

abstract：:Sirtuin1 (SIRT1) is activated during calorie restriction and appears to be related to energy balance through glucose or lipid metabolism and insulin signaling. These findings suggest that SIRT1 may play a role in the pathophysiology of visceral obesity. Therefore, we investigated the relationship between SIRT1 gene ex...

journal_title：Endocrine journal

authors： Lee H,Chu SH,Park JY,Park HK,Im JA,Lee JW

更新日期：2013-01-01 00:00:00

abstract：:Colestimide is a new anion-exchange resin used to lower serum cholesterol in Japan. Because of its excellent compliance, colestimide can replace cholestyramine. To clarify the effect of colestimide on glycemic controls, colestimide (3 g/day) or pravastatin (10 mg) was given orally to patients with type 2 diabetes trea...

journal_title：Endocrine journal

authors： Yamakawa T,Takano T,Utsunomiya H,Kadonosono K,Okamura A

更新日期：2007-02-01 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-stimulated thyroid stimulating hormone (TSH) response in normal subjects is suppressed by oral glucose administration. Pharmacologic studies indicate that this suppressive action of glucose is mediated by an increase in hypothalamic somatostatin (SRIH) tone. Since activation of the ...

journal_title：Endocrine journal

authors： Park C,Kim E,Sohn S,Yang I,Koh G,Oh S,Woo J,Kim S,Kim J,Kim Y,Oh K,Park S,Park S

更新日期：2005-02-01 00:00:00

abstract：:We examined 13 patients with euthyroid Graves' disease suspected ophthalmologically, by comparing them with 20 patients with untreated Graves' disease and by following them up for 5 to 10 years. They had Graves' ophthalmopathy (NOSPECS class II-IV) without other ocular diseases, normal levels of serum thyroid hormones...

journal_title：Endocrine journal

authors： Kashiwai T,Tada H,Asahi K,Hidaka Y,Tamaki H,Iwatani Y,Amino N

更新日期：1995-06-01 00:00:00

abstract：:The inflammatory biomarkers that fully characterize the metabolically unhealthy (MU) state-which is a risk factor for cardiovascular disease (CVD)-remain unclear. Recent studies suggest follistatin-like protein 1 (FSTL1) could be used as a biomarker for inflammation and CVD, however there is little information on FSTL...

journal_title：Endocrine journal

authors： Lee SY,Kim DY,Kyung Kwak M,Hee Ahn S,Kim H,Kim BJ,Koh JM,Rhee Y,Hwa Kim C,Hyun Baek K,Min YK,Hun Lee S,Kang MI

更新日期：2019-03-28 00:00:00

abstract：:We investigated the regulation of each intracellular signal transduction system including cyclic AMP (cAMP)-dependent and calcium (Ca2+) messenger systems in bovine adrenal fasciculo-reticularis cells to clarify the exact mode of action of ACTH. Pretreatment with primaquine and quinacrine, which are phospholipase A2 i...

journal_title：Endocrine journal

authors： Omura M,Suematsu S,Nishikawa T

更新日期：2007-08-01 00:00:00

abstract：:This study assessed the dose-dependent efficacy and safety of exenatide over 12 weeks in Japanese patients with type 2 diabetes suboptimally controlled despite therapeutic doses of sulfonylurea (SU), SU plus biguanide, or SU plus thiazolidinedione. Patients were randomly assigned to placebo (N = 40), 2.5 microg (N = 3...

journal_title：Endocrine journal

authors： Kadowaki T,Namba M,Yamamura A,Sowa H,Wolka AM,Brodows RG

更新日期：2009-01-01 00:00:00

abstract：:The present study was undertaken to determine clinical features of hypopituitarism in elderly subjects. Thirty-one elderly patients with hypopituitarism were enrolled. They were 19 males and 12 females, with the ages of 70.7±5.4 years ranging from 62 to 80 years. High prevalence of hyponatremia (80.6%) and hypoglyc...

journal_title：Endocrine journal

authors： Asano T,Aoki A,Sasaki M,Ikoma A,Kakei M,Kawakami M,Ishikawa SE

更新日期：2012-01-01 00:00:00

abstract：:We studied functional and histopathological changes in acromegalic cardiomyopathy following intermittent subcutaneous infusion of octreotide. A 68-year-old female patient with acromegaly associated with congestive heart failure due to dilated cardiomyopathy was initially treated with cardioactive medication for three ...

journal_title：Endocrine journal

authors： Nishiki M,Murakami Y,Sohmiya M,Koshimura K,Inoue K,Goto Y,Nakamura N,Kato Y

更新日期：1997-10-01 00:00:00

abstract：:Our previous studies have revealed that protein malnutrition enhances insulin signaling in rat liver and muscle in response to a bolus insulin injection. However, it has not been established whether protein malnutrition up-regulates insulin signaling under physiological conditions, such as feeding. Here, we studied th...

journal_title：Endocrine journal

authors： Toyoshima Y,Tokita R,Taguchi Y,Akiyama-Akanishi N,Takenaka A,Kato H,Chida K,Hakuno F,Minami S,Takahashi S

更新日期：2014-01-01 00:00:00

abstract：:We evaluated the concentration of epidermal growth factor (EGF) in platelets, serum and plasma obtained from 47 patients with Graves' disease, 7 with hypothyroidism and 20 healthy subjects. The platelets of the subjects were collected from platelet rich plasma and lysed by freezing and thawing. Subsequently the platel...

journal_title：Endocrine journal

authors： Okada M,Kamiya Y,Ito J,Yoshimata T,Kawaguchi M,Shibata H,Fujinami T

更新日期：1998-02-01 00:00:00

abstract：:Pseudohypoaldosteronism type 1 (PHA1) is a rare genetic disease characterized by resistance to aldosterone, and the renal form of PHA1 is associated with heterozygous inactivating mutations in NR3C2, which encodes mineralocorticoid receptor (MR). Here we report a case of renal PHA1 due to a novel frameshift mutation i...

journal_title：Endocrine journal

authors： Kawashima Sonoyama Y,Tajima T,Fujimoto M,Hasegawa A,Miyahara N,Nishimura R,Hashida Y,Hayashi A,Hanaki K,Kanzaki S

更新日期：2017-01-30 00:00:00

abstract：:Irisin is an adipokine/myokine which could be connected with insulin sensitivity. Polycystic ovary syndrome (PCOS) is characterized by oligo- or anovulation, polycystic ovary, hyperandrogenism and insulin resistance. The aim of the present study was to determine the relationship between serum irisin concentration and ...

journal_title：Endocrine journal

authors： Adamska A,Karczewska-Kupczewska M,Lebkowska A,Milewski R,Górska M,Otziomek E,Nikolajuk A,Wolczynski S,Kowalska I

更新日期：2016-12-30 00:00:00

abstract：:Previously, we reported that short-term continuous glucose monitoring (CGM) with the professional iPro2© CGM device is a good clinical indicator of glycated hemoglobin (HbA1c) levels. However, there was no significant correlation between CGM and HbA1c levels when HbA1c levels were >8.0%. To further investigate this is...

journal_title：Endocrine journal

authors： Yamada M,Okada S,Oda H,Nakajima Y,C Bastie C,Kasai Y,Osaki A,Shimoda Y,Shibusawa R,Uehara R,Saito T,Ozawa A,Yamada E

更新日期：2020-05-28 00:00:00

abstract：:It has been reported that there is an inverse relationship between serum sodium (Na) and potassium (K) levels in patients with diabetic coma. The present study was undertaken to determine whether such an inverse relation depends upon plasma glucose levels in diabetic patients for their glycemic control. We examined tw...

journal_title：Endocrine journal

authors： Saito T,Ishikawa S,Higashiyama M,Nakamura T,Rokkaku K,Hayashi H,Kusaka I,Nagasaka S,Saito T

更新日期：1999-02-01 00:00:00

abstract：:This study investigates whether urinary levels of pentosidine, pyrraline and acrolein adduct are increased in type 2 diabetes (DM), and whether these levels are correlated with glycemic control and clinical traits. Urinary levels of pentosidine, pyrraline and acrolein adduct in DM patients (n = 100) recruited from the...

journal_title：Endocrine journal

authors： Daimon M,Sugiyama K,Kameda W,Saitoh T,Oizumi T,Hirata A,Yamaguchi H,Ohnuma H,Igarashi M,Kato T

更新日期：2003-02-01 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) and its agonists have been known to directly affect steroid hormone production in human granulosa cells. In this study, we examined effects of GnRH on Ca2+ mobilization, protein kinase C activity and steroidogenesis of human granulosa cells. Human granulosa cells were harvested by...

journal_title：Endocrine journal

authors： Hori H,Uemura T,Minaguchi H

更新日期：1998-04-01 00:00:00

abstract：:This is a case report of an 18-year-old man with central diabetes incipidus (DI). An MRI done three months after the onset of the DI did not disclose a responsible lesion. Four months later, a second MRI showed the location of the tumor origin at the upper pituitary stalk and median eminence. Eight months later, the t...

journal_title：Endocrine journal

authors： Saeki N,Uchida D,Tatsuno I,Saito Y,Yamaura A

更新日期：1999-04-01 00:00:00

abstract：:Musk is a secreted external hormone or information compound that is stored in musk scent glands of the males of species within the family Moschidae, such as Moschus berezovskii. The secretion of musk changes periodically during the courtship and reproduction periods, with the early stage of secretion occurring from Ma...

journal_title：Endocrine journal

authors： Fan M,Zhang M,Shi M,Zhang T,Qi L,Yu J,Li X,Lin S,Huang Z,Yang S,Zhou J,Li Y,Sun X,Cha M,Xu S,Liu Y,Guo X,Hu D,Liu S

更新日期：2018-11-29 00:00:00

abstract：:Estrogen plays pivotal roles in body weight regulation through its effects on central estrogen receptor-α (ERα) expression. ERα is found on neurons that express the hypothalamic anorexigenic factors steroidogenic factor-1 (SF-1) and pro-opiomelanocortin (POMC) mediate these effects of estrogen. As the gonadal hormonal...

journal_title：Endocrine journal

authors： Iwasa T,Matsuzaki T,Mayila Y,Yano K,Irahara M

更新日期：2017-12-28 00:00:00

abstract：:To evaluate the prevalence of lymphocytic infiltrate in a large series of pituitary adenomas, we retrospectively studied tumor tissues from 1400 patients. Based on immunocytochemical data, tumors were classified as PRL (n=411), multihormonal (n=310), immunonegative (n=275), ACTH (n=166), GH (n=137), alpha subunit (n=4...

journal_title：Endocrine journal

authors： Heshmati HM,Kujas M,Casanova S,Wollan PC,Racadot J,Van Effenterre R,Derome PJ,Turpin G

更新日期：1998-06-01 00:00:00

abstract：:The relation between thyroid ultrasonography and laboratory, and the relationship of thyroid volume with clinical and anthropometric parameters, are not well clarified. Aim of the study was to investigate normal and hypoechoic-inhomogeneous not nodular thyroid gland in predicting thyroid tests, and to assess the corre...

journal_title：Endocrine journal

authors： Trimboli P,Rossi F,Thorel F,Condorelli E,Laurenti O,Ventura C,Nigri G,Romanelli F,Guarino M,Valabrega S

更新日期：2012-01-01 00:00:00

abstract：:Recent studies indicate that succinate dehydrogenase (SDH) genes B, C, or D are, at least partly, involved in the pathogenesis of pheochromocytoma or paraganglioma. Of these three genes, the SDHD gene mutation is most closely related with paragangliomas of the neck. Here we describe a case of an SDHD-related paragangl...

journal_title：Endocrine journal

authors： Yamashita R,Usui T,Hashimoto S,Suzuki H,Takahashi M,Honkura K,Iwamoto K,Kodama E,Tagami T,Naruse M,Shimatsu A,Kaise K

更新日期：2009-01-01 00:00:00

abstract：:Unusual presentations with bone, lung or soft tissue metastases in initial diagnosis of follicular thyroid carcinoma have been reported occasionally. This implies how difficult it is to diagnosis this type of cancer at the pre-operative or intra-operative stage of treatment. Fine needle aspiration cytology has been sh...

journal_title：Endocrine journal

authors： Lin JD,Chao TC

更新日期：2006-08-01 00:00:00