Travel epidemiology: the Saudi perspective.

Abstract:

:The Kingdom of Saudi Arabia occupies four-fifths of the Arabian Peninsula, with a land area of 2 million square kilometres. Saudi Arabia holds a unique position in the Islamic world, as the custodian of the two holiest places of Islam, in Mecca and Medina. Annually, some 2 million Muslims from over 140 countries embark on Hajj. This extraordinary en masse migration is a unique forum for the study of travel epidemiology since the Hajj carries various health risks, both communicable and non-communicable, often on a colossal scale. Non-communicable hazards of the Hajj include stampede and motor vehicle trauma, fire-related burn injuries and accidental hand injury during animal slaughter. Communicable hazards in the form of outbreaks of multiple infectious diseases have been reported repeatedly, during and following the Hajj. Meningococcal meningitis, gastroenteritis, hepatitis A, B and C, and various zoonotic diseases comprise some of the possible infectious hazards at the Hajj. Many of these infectious and non-infectious hazards can be avoided or averted by adopting appropriate prophylactic measures. Physicians and health personnel must be aware of these risks to appropriately educate, immunize and prepare these travellers facing the unique epidemiological challenges of Hajj in an effort to minimize untoward effects. Travel epidemiology related to the Hajj is a new and exciting area, which offers valuable insights to the travel specialist. The sheer scale of numbers affords a rare view of migration medicine in action. As data is continually gathered and both national and international policy making is tailored to vital insights gained through travel epidemiology, the Hajj will be continually safeguarded. Practitioners will gain from findings of travel related epidemiological changes in evolution at the Hajj: the impact of vaccinating policies, infection control policies and public health are afforded a real-world laboratory setting at each annual Hajj, allowing us to learn from this unique phenomenon of migration medicine.

authors

Memish ZA,Venkatesh S,Ahmed QA

doi

10.1016/s0924-8579(02)00364-3

subject

Has Abstract

pub_date

2003-02-01 00:00:00

pages

96-101

issue

2

eissn

0924-8579

issn

1872-7913

pii

S0924857902003643

journal_volume

21

pub_type

杂志文章
  • Developments in PK/PD: optimising efficacy and prevention of resistance. A critical review of PK/PD in in vitro models.

    abstract::In vitro pharmacokinetic models are excellent tools with which to study an antibacterial's pharmacodynamics (pD), being flexible, adaptable, low cost, and correlating well with animal and human systems. They can be used to perform simple descriptive studies on antibacterial effect, determine the dominant pD factor and...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/s0924-8579(02)00027-4

    authors: MacGowan A,Bowker K

    更新日期:2002-04-01 00:00:00

  • Recombinant human erythropoietin for treatment of anemia in persons with AIDS not receiving zidovudine.

    abstract::Because few data exist on the effect of recombinant human erythropoietin (EPO) for anemia not induced by zidovudine (ZDV) in persons with AIDS, we analyzed a subset of 523 subjects not taking ZDV ('non-ZDV') who participated in an open-label EPO treatment program involving 1943 subjects. Non-ZDV subjects had a mean he...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(97)00371-3

    authors: Balfour HH Jr

    更新日期:1997-01-01 00:00:00

  • Use of imipenem as empirical treatment of febrile neutropenia.

    abstract::Based on past information from the literature and our own review, it appears that imipenem can be used effectively as an initial empirical therapy of febrile neutropenia, as a monotherapy, even in patients with haematological malignancies. The response rate is outstanding in microbiologically documented infections, na...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/s0924-8579(03)00002-5

    authors: Klastersky JA

    更新日期:2003-05-01 00:00:00

  • Dichotomous selection of high-level oxacillin resistance in Staphylococcus aureus by fluoroquinolones.

    abstract::The objective of this study was to determine whether exposure of Staphylococcus aureus to early (ciprofloxacin or levofloxacin) and a recent fluoroquinolone (moxifloxacin) has differential potential as a mutator or selector for meticillin resistance. The potential of fluoroquinolones to act as mutators or selectors wa...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2010.04.014

    authors: Dalhoff A,Schubert S

    更新日期:2010-09-01 00:00:00

  • Pharmacokinetics of intracellular zidovudine and its phosphorylated anabolites in the absence and presence of stavudine using an in vitro human peripheral blood mononuclear cell (PBMC) model.

    abstract::Both zidovudine (ZDV) and stavudine (D4T) must be intracellularly converted to their respective active triphosphate anabolites (ZDV-TP and D4T-TP). It is hypothesized that the combination of ZDV and D4T may lead to altered formation of phosphorylated anabolites for either drug. The objective of this study was to inves...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(97)00041-1

    authors: Brody SR,Aweeka FT

    更新日期:1997-09-01 00:00:00

  • Crossover assessment of serum bactericidal activity of grepafloxacin, ofloxacin and clarithromycin against respiratory pathogens after oral administration to healthy volunteers.

    abstract::Serum bactericidal activity was studied in a crossover manner in 10 volunteers, after 2-day administration of grepafloxacin 600 mg qd, ofloxacin 400 mg bid and clarithromycin 500 mg bid. Bactericidal activity against clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Klebs...

    journal_title:International journal of antimicrobial agents

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0924-8579(01)00333-8

    authors: Dan M,Poch F,Asherov J

    更新日期:2001-06-01 00:00:00

  • Eradication of meticillin-resistant Staphylococcus aureus from human skin by the novel LL-37-derived peptide P10 in four pharmaceutical ointments.

    abstract::Skin bacterial colonization/infection is a frequent cause of morbidity in patients with chronic wounds and allergic/inflammatory skin diseases. This study aimed to develop a novel approach to eradicate meticillin-resistant Staphylococcus aureus (MRSA) from human skin. To achieve this, the stability and antibacterial a...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2019.07.014

    authors: Nibbering PH,Göblyös A,Adriaans AE,Cordfunke RA,Ravensbergen B,Rietveld MH,Zwart S,Commandeur S,van Leeuwen R,Haisma EM,Schimmel KJM,den Hartigh J,Drijfhout JW,Ghalbzouri AE

    更新日期:2019-11-01 00:00:00

  • Targeting antimicrobial drug resistance with marine natural products.

    abstract::The rise and spread of antimicrobial resistance represents one of the most pressing health issues of today. Antimicrobial resistance in micro-organisms can arise due to a multiplicity of factors, including permeability changes in the cell membrane, increase of drug efflux pumps, enzymatic modification or inactivation ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijantimicag.2020.106005

    authors: Barbosa F,Pinto E,Kijjoa A,Pinto M,Sousa E

    更新日期:2020-07-01 00:00:00

  • Emergence of colistin resistance in Pseudomonas aeruginosa ST235 clone in South Korea.

    abstract::In this study, the prevalence and characteristics of metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa isolates in South Korea were investigated. Among 215 P. aeruginosa isolates collected from eight hospitals, 77 (35.8%) and 72 (33.5%) were resistant to imipenem and meropenem, respectively. Of the 77 imipene...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2017.01.023

    authors: Wi YM,Choi JY,Lee JY,Kang CI,Chung DR,Peck KR,Song JH,Ko KS

    更新日期:2017-06-01 00:00:00

  • Antibacterial activity of high concentrations of carvedilol against Gram-positive and Gram-negative bacteria.

    abstract::Many drugs used to treat non-infectious diseases have also shown excellent antibacterial activity or the ability to enhance the action of antibiotics. The aim of this study was to investigate the antibacterial activity of a popular β-blocker, carvedilol, and its mechanism of antibacterial action. The antibacterial act...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2017.12.014

    authors: Zawadzka K,Bernat P,Felczak A,Różalska S,Lisowska K

    更新日期:2018-03-01 00:00:00

  • The effect of food on plasma and tissue concentrations of linezolid after multiple doses.

    abstract::In the present pilot study we investigated the effect of food ingestion on target site pharmacokinetics of linezolid, the first clinically approved oxazolidinone. For this purpose we determined free concentrations of linezolid at steady state in the interstitial space fluid of skeletal muscle and subcutaneous adipose ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2005.09.017

    authors: Islinger F,Dehghanyar P,Sauermann R,Bürger C,Kloft C,Müller M,Joukhadar C

    更新日期:2006-02-01 00:00:00

  • High prevalence of plasmid-mediated quinolone resistance determinant aac(6')-Ib-cr amongst Salmonella enterica serotype Typhimurium isolates from hospitalised paediatric patients with diarrhoea in China.

    abstract::In this study, the antimicrobial susceptibilities and prevalence of plasmid-mediated quinolone resistance determinants amongst Salmonella enterica serotype Typhimurium isolates from hospitalised paediatric patients with diarrhoea in China were investigated. In total, 40 (64.5%) of 62 S. Typhimurium isolates were resis...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2010.10.021

    authors: Yu F,Chen Q,Yu X,Pan J,Li Q,Yang L,Chen C,Zhuo C,Li X,Zhang X,Huang J,Wang L

    更新日期:2011-02-01 00:00:00

  • Antistaphylococcal penicillins versus cephalosporins for definitive treatment of meticillin-susceptible Staphylococcus aureus bacteraemia: a systematic review and meta-analysis.

    abstract::The objective of this study was to assess the comparative effectiveness and safety of antistaphylococcal penicillins (ASPs) and cephalosporins for the definitive treatment of patients with meticillin-susceptible Staphylococcus aureus (MSSA) bacteraemia. PubMed and Scopus electronic databases were searched up to Decemb...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ijantimicag.2014.09.002

    authors: Vardakas KZ,Apiranthiti KN,Falagas ME

    更新日期:2014-12-01 00:00:00

  • In vitro susceptibility of Achromobacter spp. isolates: comparison of disk diffusion, Etest and agar dilution methods.

    abstract::In this study, we analysed the antimicrobial susceptibility of 92 strains of Achromobacter spp. isolated from clinical samples to 18 antimicrobial agents. The disk diffusion method and Etest were compared with the agar dilution method, and the breakpoints of susceptibility and resistance for the disk diffusion method ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2009.08.015

    authors: Almuzara M,Limansky A,Ballerini V,Galanternik L,Famiglietti A,Vay C

    更新日期:2010-01-01 00:00:00

  • Combined treatment of Pseudomonas aeruginosa biofilm with lactoferrin and xylitol inhibits the ability of bacteria to respond to damage resulting from lactoferrin iron chelation.

    abstract::With an ageing and ever more obese population, chronic wounds such as diabetic ulcers, pressure ulcers and venous leg ulcers are an increasingly relevant medical concern. Identification of bacterial biofilm contamination as a major contributor to non-healing wounds demands biofilm-targeted strategies to manage chronic...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2010.12.019

    authors: Ammons MC,Ward LS,Dowd S,James GA

    更新日期:2011-04-01 00:00:00

  • The effect of Nepeta cataria extract on adherence and enzyme production of Staphylococcus aureus.

    abstract::Nepeta cataria L., commonly known as catnip, is a perennial herb with a considerable folkloric reputation. A diethyl ether extract of this plant has been shown to have antimicrobial activity against fungi and Gram-positive bacteria. The aim of this work was to study the activity of N. cataria extract on 44 Staphylococ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(01)00452-6

    authors: Nostro A,Cannatelli MA,Crisafi G,Alonzo V

    更新日期:2001-12-01 00:00:00

  • Trends in antimicrobial susceptibility of bacterial pathogens isolated from patients with bloodstream infections in the USA, Canada and Latin America. SENTRY Participants Group.

    abstract::From January through June of 1998, 4579 bloodstream infections (BSI) due to bacterial pathogens were reported from SENTRY hospitals in Canada, the USA and Latin America. Staphylococcus aureus, Escherichia coli, and coagulase-negative staphylococcus (CoNS) were the most common pathogens, together accounting for 55.2% o...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(99)00131-4

    authors: Diekema DJ,Pfaller MA,Jones RN,Doern GV,Kugler KC,Beach ML,Sader HS

    更新日期:2000-02-01 00:00:00

  • Population pharmacokinetics and dosing optimization of latamoxef in neonates and young infants.

    abstract:OBJECTIVES:There has been recent renewed interest in historical antibiotics because of the increased antibiotic-resistant bacterial strains. Latamoxef, a semi-synthetic oxacephem antibiotic developed in 1980s, has recently been brought back into use for treatment of infections in newborns; however, it is still used off...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2018.11.017

    authors: Qi H,Kou C,Qi YJ,Tang BH,Wu YE,Jin F,Luo XJ,Shen YH,Guo YJ,Qi X,Wang YC,Dong Q,Chen XK,Shi HY,Zheng Y,Zhao W,Shen AD

    更新日期:2019-03-01 00:00:00

  • In vitro activity of four fluoroquinolones against clinical isolates of Pseudomonas aeruginosa determined by the E test.

    abstract::Ciprofloxacin, levofloxacin, ofloxacin, and trovafloxacin were tested by the E-test against 100 clinical isolates of Pseudomonas aeruginosa. Ciprofloxacin was the most active of the tested agents with 82% of isolates having a MIC 8). Levofloxacin and trovafloxacin had nearly identical potency:...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/s0924-8579(00)00132-1

    authors: Swiatlo E,Moore E,Watt J,McDaniel LS

    更新日期:2000-06-01 00:00:00

  • Wide distribution of CC92 carbapenem-resistant and OXA-23-producing Acinetobacter baumannii in multiple provinces of China.

    abstract::Carbapenem-resistant Acinetobacter baumannii has spread rapidly across China and is currently reported to be a worldwide nosocomial menace. In light of its increasing clinical significance, this study aimed to investigate the molecular epidemiology of carbapenem-resistant and carbapenem-susceptible isolates obtained f...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2013.06.019

    authors: Ruan Z,Chen Y,Jiang Y,Zhou H,Zhou Z,Fu Y,Wang H,Wang Y,Yu Y

    更新日期:2013-10-01 00:00:00

  • Five-year trends for ventilator-associated pneumonia: Correlation between microbiological findings and antimicrobial drug consumption.

    abstract::The epidemiology of multidrug-resistant bacteria (MDRB) has changed significantly in European healthcare settings, with a decrease in frequency of meticillin-resistant Staphylococcus aureus and an increase in extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. Little is known about the effects of these ...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2015.07.010

    authors: Fihman V,Messika J,Hajage D,Tournier V,Gaudry S,Magdoud F,Barnaud G,Billard-Pomares T,Branger C,Dreyfuss D,Ricard JD

    更新日期:2015-11-01 00:00:00

  • Mutant prevention concentration: a new tool for choosing treatment in nontuberculous mycobacterial infections.

    abstract::The mutant prevention concentration (MPC) of fluoroquinolones, linezolid, rifabutin, rifampicin and macrolides was determined in 16 nontuberculous Mycobacterium species in order to compare the incidence of resistant mutant occurrence for different antibiotics. Linezolid showed good activity against Mycobacterium gordo...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2004.03.026

    authors: Rodríguez JC,Cebrián L,López M,Ruiz M,Royo G

    更新日期:2004-10-01 00:00:00

  • Mutant prevention concentration for ciprofloxacin and levofloxacin with Pseudomonas aeruginosa.

    abstract::The mutant prevention concentration (MPC) was determined by population analysis using six fluoroquinolone-susceptible isolates of Pseudomonas aeruginosa applied to fluoroquinolone-containing agar plates. The MPCs were 3 mg/L and 9.5 mg/L for ciprofloxacin and levofloxacin, respectively. At high concentrations of eithe...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2005.10.005

    authors: Hansen GT,Zhao X,Drlica K,Blondeau JM

    更新日期:2006-02-01 00:00:00

  • Multidrug-resistant high-risk Enterococcus faecium clones: can we really define them?

    abstract::Enterococcus faecium is a significant opportunistic human pathogen with a broad host range, including humans, farm animals, pets and wildlife. Specialised subpopulations have globally evolved towards a powerful and convergent adaption to the healthcare environment by acquiring a cocktail of key antimicrobial resistanc...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijantimicag.2020.106227

    authors: Freitas AR,Pereira AP,Novais C,Peixe L

    更新日期:2021-01-01 00:00:00

  • Antibiotics enhance binding of lipid A-specific murine monoclonal antibody E5 to Gram-negative bacteria.

    abstract::Cross-protection by anti-lipid A antibodies may be mediated by contribution to host defence mechanisms such as enhancement of bactericidal activity and phagocytosis. The lipid A-specific murine monoclonal antibody (mAb) E5 was evaluated in vitro for its ability to enhance antibacterial effects in concert with antibiot...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/0924-8579(94)90008-6

    authors: Bouter AS,van Kessel KP,Cornelissen JJ,Schellekens JF,van der Hoek YY,Snippe H,Verhoef J

    更新日期:1994-08-01 00:00:00

  • Fluoroquinolone resistance of Pseudomonas aeruginosa isolates causing nosocomial infection is correlated with levofloxacin but not ciprofloxacin use.

    abstract::This study investigated the correlation between fluoroquinolone (ciprofloxacin or levofloxacin) use and rates of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from patients with nosocomial infection at a medical centre in Taiwan. Antibiotic utilisation data were extracted on a monthly basis from the in...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2009.11.007

    authors: Lee YJ,Liu HY,Lin YC,Sun KL,Chun CL,Hsueh PR

    更新日期:2010-03-01 00:00:00

  • Conclusions: the future of antimicrobial therapy - Augmentin and beyond.

    abstract::Since most infectious microorganisms inevitably develop resistance to any agents used to combat them, there has been a constant need to produce improved, more potent, antimicrobials. At least in part, the emergence and spread of resistant organisms has been provoked by inappropriate over-use of antibacterials. In the ...

    journal_title:International journal of antimicrobial agents

    pub_type: 历史文章,杂志文章,评审

    doi:10.1016/j.ijantimicag.2007.08.016

    authors: Ball P

    更新日期:2007-12-01 00:00:00

  • Comparative analysis and distribution of pP9014, a novel drug resistance IncP-1 plasmid from Photobacterium damselae subsp. piscicida.

    abstract::Photobacterium damselae subsp. piscicida, a causative agent of pseudotuberculosis, often harbours resistance plasmids (R plasmids) that facilitate horizontal gene transfer of drug resistance genes. R plasmid pP9014 was isolated from P. damselae subsp. piscicida and its complete nucleotide sequence was determined using...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2013.02.027

    authors: del Castillo CS,Jang HB,Hikima J,Jung TS,Morii H,Hirono I,Kondo H,Kurosaka C,Aoki T

    更新日期:2013-07-01 00:00:00

  • Characterisation and risk factor profiling of Pseudomonas aeruginosa urinary tract infections: pinpointing those likely to be caused by multidrug-resistant strains.

    abstract::This study aimed to characterise UTIs caused by Pseudomonas aeruginosa in hospitalised adults and to identify risk factors for infections caused by multidrug-resistant (MDR) strains. A retrospective case-case-control study was conducted in two Italian teaching hospitals. Totally, 242 monomicrobial P. aeruginosa UTIs w...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2020.105900

    authors: Tumbarello M,Raffaelli F,Peghin M,Losito AR,Chirico L,Giuliano G,Spanu T,Sartor A,Fiori B,Bassetti M

    更新日期:2020-04-01 00:00:00

  • Prevalence of plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases in Spain.

    abstract::The presence of the plasmid-mediated quinolone resistance determinants qnrA, qnrB, qnrS and aac(6')-Ib-cr was evaluated in a collection of 382 isolates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae collected between February and March 2006 for the nationwide Spanish GEIH-...

    journal_title:International journal of antimicrobial agents

    pub_type: 杂志文章

    doi:10.1016/j.ijantimicag.2011.12.009

    authors: Briales A,Rodríguez-Martínez JM,Velasco C,de Alba PD,Rodríguez-Baño J,Martínez-Martínez L,Pascual A

    更新日期:2012-05-01 00:00:00