Rectal pressure response to a meal in patients with high spinal cord injury.

Abstract:

OBJECTIVES:To determine whether there is a postprandial increase of rectal pressure in patients with spinal cord injury (SCI) and to compare their rectal pressures with those of healthy volunteers. DESIGN:A before-after trial comparing SCI and control subjects. SETTING:Patients were recruited from the register of an SCI unit at a rehabilitation medicine department, and the study took place at the university hospital laboratory in Sweden. PARTICIPANTS:Ten patients with high traumatic SCI and 9 healthy volunteers. Eight patients had a lesion above level T5. INTERVENTION:Continuous anorectal manometry was performed. Rectal activity was calculated before and at regular time intervals after a 1000-cal test meal. MAIN OUTCOME MEASURE:Rectal activity measured as area under the pressure curve. RESULTS:There was a significant increase in rectal activity of 46% after 10 minutes in the patients but of 72% after 5 minutes in the volunteers. There was no difference in fasting rectal activity, but patients had a stronger mean rectal postprandial response during 60 minutes compared with volunteers. CONCLUSIONS:These results support the theory that the colonic response to food is preserved in patients with high SCI.

journal_name

Arch Phys Med Rehabil

authors

Walter SA,Morren GL,Ryn AK,Hallböök O

doi

10.1053/apmr.2003.50071

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

108-11

issue

1

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(02)04889-X

journal_volume

84

pub_type

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