Abstract:
:In this study, 36 extracts derived from 29 plant species selected using an ethnobotanical approach were tested for antifungal activity against a taxonomically diverse group of 13 human pathogenic fungi. We compared the inhibitory characteristics of these plant extracts with those of the commonly used antifungals, amphotericin B and ketoconazole, and the plant-derived antifungal, berberine. Several plant extracts, notably those from Zingiber officinale (ginger) and Juglans cinerea (butternut), had pronounced antifungal activity against a wide variety of fungi, including strains that were highly resistant to amphotericin B and ketoconazole. Further exploration of Z. officinale as an antifungal is warranted as this species is generally regarded as safe for human consumption.
journal_name
Mycosesjournal_title
Mycosesauthors
Ficker CE,Arnason JT,Vindas PS,Alvarez LP,Akpagana K,Gbéassor M,De Souza C,Smith MLdoi
10.1046/j.1439-0507.2003.00838.xsubject
Has Abstractpub_date
2003-02-01 00:00:00pages
29-37issue
1-2eissn
0933-7407issn
1439-0507pii
838journal_volume
46pub_type
杂志文章相关文献
MYCOSES文献大全abstract::The objective of this study was to compare phospholipase production between fluconazole-resistant and fluconazole-susceptible strains of Candida albicans in order to explore the relationship between resistance to antifungal drugs and virulence of C. albicans. Fifteen each of fluconazole-resistant (MIC ≥ 64 μg ml(-1)) ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2011.02024.x
更新日期:2012-01-01 00:00:00
abstract:UNLABELLED:Cryptococcosis is frequently associated to the immune reconstitution inflammatory syndrome (IRIS) in AIDS patients on highly active antiretroviral therapy (HAART). This study aimed to evaluate clinical and evolutive features of IRIS associated cryptococcosis patients in Uberaba, Brazil. PATIENTS:Eighty-one ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2010.01870.x
更新日期:2011-07-01 00:00:00
abstract::Recent observations on reciprocal regulation of humoral and cell-mediated immunity to Candida albicans are presented and their significance in the exploration of the host-fungus-relationship is discussed. ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1999.tb00012.x
更新日期:1999-12-01 00:00:00
abstract::Orointestinal mycoses are localized mainly in the oral cavity and in the oesophagus. Candida oesophagitis is not only found in AIDS-patients, also in patients of risk admitted to intensive care units. Upper intestinoscopies were made in 124 patients. Oesophageal candidosis was found in 6 patients, two of them had also...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1999.tb04531.x
更新日期:1999-01-01 00:00:00
abstract::The growth and viability of two Paracoccidioides brasiliensis strains were evaluated in PYG and MMcM media containing no boric acid. The two P. brasiliensis strains exhibited a similar growth pattern in PYG medium, which was considered to be good compared with the growth curves in defined MMcM medium without boric aci...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1996.tb00108.x
更新日期:1996-03-01 00:00:00
abstract::Candida kefyr is an emerging pathogen able to cause disseminated infection, especially in immunocompromised patients. Although guidelines for the treatment of invasive candidiasis have been published, no specific recommendations against C. kefyr are available. We determine the in vitro killing activity of amphotericin...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12468
更新日期:2016-04-01 00:00:00
abstract::The role of Malassezia furfur adherence to human stratum corneum cells in vitro was studied. The adherence assay was performed with one strain of M. furfur and stratum corneum cells from 30 healthy individuals and from 28 patients with seborrhoeic dermatitis. Stratum corneum cells from patients with seborrhoeic dermat...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1994.tb00303.x
更新日期:1994-06-01 00:00:00
abstract::Eleven clinical and veterinary strains of filamentous Basidiomycetes were compared with 15 reference strains representing the orders Aphyllophorales and Agaricales. The methods used were restriction analysis of small subunit (18S) (SSU) rDNA and internal transcribed spacers (ITS) 1 and 2 and variable domain 9 (V9)-ITS...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1998.tb00321.x
更新日期:1998-05-01 00:00:00
abstract::Perforative eye injuries in two patients were complicated by fulminant endophthalmitis. In both patients the cornea was free of micro-organisms. Vitrectomy of the posterior pars plana was performed and the contents of the vitreous body were examined mycologically and bacteriologically. Fusarium moniliforme var. subglu...
journal_title:Mycoses
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:To assess the diagnostic value of serum Candida mannan antigen (MN) and anti-mannan IgG and IgM antibodies for candidiasis. METHODS:This study was a prospective cohort study. Clinical data and venous blood samples from 23 medical centres in Beijing, China were collected between 1 January 2017 and 31 December...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.13035
更新日期:2020-02-01 00:00:00
abstract::With advances in medical sciences, an increase in survival rates of low birth weight; increased incidence in use of catheter and antibiotics, and total parenteral nutrition are reported, therefore, the rate of fungal infections in late and very late onset neonatal sepsis have increased. Although fungal endocarditis ra...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/myc.12359
更新日期:2015-10-01 00:00:00
abstract::Peptidorhamnomannans (PRMs), rhamnomannans and α-glucans are especially relevant for the architecture of the Scedosporium/Pseudallescheria boydii cell wall, but many of them are immunologically active, with great potential as regulators of pathogenesis and the immune response of the host. In addition, some of them can...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0507.2011.02105.x
更新日期:2011-10-01 00:00:00
abstract::The objective of this study was to compare polymerase chain reaction (PCR) fingerprinting with other molecular typing methods as an epidemiologic tool to investigate the transmission of Candida strains between HIV-positive mothers and their children. Forty-nine yeast strains (including Candida albicans, Candida glabra...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1046/j.1439-0507.1999.00479.x
更新日期:1999-01-01 00:00:00
abstract::In pooled samples of faeces from 25 pet bird flocks in Thuringia, a high rate of contamination with Cryptococcus neoformans var. neoformans was found. The prevalence of Cr. neoformans in the bird-breeding establishments correlated with the numbers of the different pet bird species in these flocks. The differentiation ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1046/j.1439-0507.2000.00534.x
更新日期:2000-01-01 00:00:00
abstract::Pityriasis versicolor (PV) is a superficial fungal infection where Malassezia species play a definite causative role, but the clinical significance of each of these species is not fully understood. The aim of our study was to analyse the prevalence of Malassezia species in PV lesions and to examine if the range of spe...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2006.01310.x
更新日期:2007-01-01 00:00:00
abstract::Bacterial superinfections often occur in dermatomycoses, resulting in greatly inflamed or eczematous skin. The objective of this study was to evaluate the antibacterial efficacy of isoconazole nitrate (ISN), a broad-spectrum antimicrobial imidazole, commonly used to treat dermatomycoses. Several gram-positive bacteria...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12055
更新日期:2013-05-01 00:00:00
abstract::We describe an African histoplasmosis case in a 65-year-old Belgian living in Zaire for 46 years. Microscopic bone marrow examination showed Histoplasma. It was confirmed by cultures and hamster inoculation. Autopsy revealed a fungal dissemination by Histoplasma duboisii. ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1991.tb00620.x
更新日期:1991-01-01 00:00:00
abstract::Many studies have described the adherence of Candida albicans to epithelial cells but little is known about Candida parapsilosis adhesion and its role in host cell surface recognition. This study was designed to evaluate the correlation between the adherence of 20 C. albicans and 12 C. parapsilosis strains to human bu...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2009.01757.x
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Histoplasmosis is a frequent fungal infection in HIV/AIDS patients, with high morbimortality rates when diagnosis and treatment are delayed. Antibody detection, which is faster than the gold standard culture test, hastens the laboratory investigation. OBJECTIVES:To evaluate the role of WB for antibody detec...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12877
更新日期:2019-03-01 00:00:00
abstract::Six cases of tinea of the scrotum with atypical clinical features were observed in the dermatology department of our hospital between 2001 and 2007. The age of onset ranged from 14 to 26 years. Unusual clinical presentations of pseudomembranous-like disease were observed in every patient. Causative agents were Microsp...
journal_title:Mycoses
pub_type: 信件
doi:10.1111/j.1439-0507.2008.01557.x
更新日期:2009-05-01 00:00:00
abstract::Onychomycosis was considered uncommon in children. This survey was carried out to estimate the frequency of fungal nail infections in children and adolescents (0-18 years of age) attending our clinic in the last decade and gain more insight into the aetiology and clinics of this entity in the paediatric age group. Thi...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2005.01186.x
更新日期:2006-01-01 00:00:00
abstract::The Clinical and Laboratory Standard Institute (CLSI) revised the clinical breakpoints (CBPs) for the azoles and echinocandins against Candida species in 2012. We aimed to report the epidemiology of candidemia and antifungal susceptibility of Candida species and evaluate the impact of new CBPs on antifungal susceptibi...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12553
更新日期:2017-02-01 00:00:00
abstract::We report a case of cerebral mucormycosis in a 28-year-old male who was affected by chronic myeloid leukaemia and underwent allogeneic bone marrow transplantation. Nine months post-transplantation, he was admitted to the hospital with fever, bilateral eyelid oedema and neutropenia. X-ray analysis showed numerous areas...
journal_title:Mycoses
pub_type: 信件
doi:10.1111/j.1439-0507.2009.01689.x
更新日期:2010-05-01 00:00:00
abstract::Heat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up-regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties. A possible cellular heat shock response was inves...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2010.01933.x
更新日期:2011-09-01 00:00:00
abstract::The standard methods for yeast susceptibility testing require 24-48 h of incubation. As there has been an increase in incidence of non-albicans Candida species, the clinician is very often wary of initiating therapy with fluconazole until a final susceptibility report is generated, especially when treating very sick p...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2007.01466.x
更新日期:2008-05-01 00:00:00
abstract::In an 84-year-old man cryptococcosis with a pronounced osteomyelitic course (involvement of a rib, two thoracic vertebrae, the sacrum and a femur) was diagnosed histologically post mortem, thus directing attention to cryptococcosis in advanced age. The presumptive chronic course of the Cryptococcus neoformans (Cr. n.)...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/myc.1990.33.4.157
更新日期:1990-04-01 00:00:00
abstract:PURPOSE:We aimed to implement and to assess the impact of the antifungal stewardship programme (AFSp) on prescription appropriateness of antifungals, management and outcomes of candidaemia patients, and antifungal consumption and costs at our solid organ transplant (SOT) institute. METHODS:Local epidemiology of invasi...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.13098
更新日期:2020-07-01 00:00:00
abstract::Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most common pharmacological agents. They have three primary therapeutic properties including anti-inflammatory, anti-pyretic and analgesic effects. Seven NSAIDs were tested against two species of dermatophytes. Percentage inhibition was determined for effec...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2010.01945.x
更新日期:2011-09-01 00:00:00
abstract::Eight cases of imported mycetomata in The Netherlands are reviewed. Seven of these were cultured; only one isolate, Actinomadura madurae, belonged to a species commonly known as an agent of mycetoma. The remaining strains either belonged to very rare species, such as Phialophora cyanescens, or could not be identified ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1993.tb00693.x
更新日期:1993-03-01 00:00:00
abstract::The Aspergillus fumigatus group splits into the anamorphic A. fumigatus series and the teleomorphic Neosartorya fischeri series. The species A. fumigatus Fresenius is the most common species within the A. fumigatus series. Forty-seven clinical isolates out of the A. fumigatus group were obtained from patients with dis...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1997.tb00248.x
更新日期:1997-12-01 00:00:00