Inhibition of human pathogenic fungi by ethnobotanically selected plant extracts.

Abstract:

:In this study, 36 extracts derived from 29 plant species selected using an ethnobotanical approach were tested for antifungal activity against a taxonomically diverse group of 13 human pathogenic fungi. We compared the inhibitory characteristics of these plant extracts with those of the commonly used antifungals, amphotericin B and ketoconazole, and the plant-derived antifungal, berberine. Several plant extracts, notably those from Zingiber officinale (ginger) and Juglans cinerea (butternut), had pronounced antifungal activity against a wide variety of fungi, including strains that were highly resistant to amphotericin B and ketoconazole. Further exploration of Z. officinale as an antifungal is warranted as this species is generally regarded as safe for human consumption.

journal_name

Mycoses

journal_title

Mycoses

authors

Ficker CE,Arnason JT,Vindas PS,Alvarez LP,Akpagana K,Gbéassor M,De Souza C,Smith ML

doi

10.1046/j.1439-0507.2003.00838.x

subject

Has Abstract

pub_date

2003-02-01 00:00:00

pages

29-37

issue

1-2

eissn

0933-7407

issn

1439-0507

pii

838

journal_volume

46

pub_type

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