Abstract：
:Using the optical disector for quantifying cell numbers, we investigated whether oral treatment of rats on days 6-21 of gestation with the weakly estrogenic bisphenol A (BPA, 0.1 or 50 mg/kg) or the highly estrogenic ethinyl estradiol (EE, 0.02 mg/kg) alters testicular histology, in those offspring 9-12 month of age. Since production of male germ cells depends on Sertoli cell number, possible changes in that parameter were investigated using unbiased stereology. Spermatogenesis was qualitatively normal in all groups. BPA increases Sertoli cell number per organ but not when expressed as per gram testis. EE did not affect cell number per organ but did affect numbers on a per gram testis basis due to a lowered testis weight. In contrast to the lowering of Sertoli cell numbers that might have been expected according to the estrogen hypothesis, intrauterine administration of these xenoestrogens in fact resulted in minor increases in Sertoli cell numbers and had no qualitative effect on spermatogenesis.
journal_name
Environ Resjournal_title
Environmental researchauthors
Wistuba J,Brinkworth MH,Schlatt S,Chahoud I,Nieschlag Edoi
10.1016/s0013-9351(02)00019-1subject
Has Abstractpub_date
2003-02-01 00:00:00pages
95-103issue
2eissn
0013-9351issn
1096-0953pii
S0013935102000191journal_volume
91pub_type
杂志文章abstract：:The intestinal absorption of arsenate(As(V)) has been investigated in the chick by means of the in situ ligated duodenal loop technique. By this procedure, it was observed that arsenate is rapidly and essentially completely absorbed (80-95%) from the lumen at As(V) concentrations up to 5 mM, declining to about 50% abs...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(85)90018-0
更新日期：1985-02-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2007-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2007-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2008-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110050
更新日期：2020-12-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2019-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章,评审
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更新日期：2016-05-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.12.013
更新日期：2017-04-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.03.045
更新日期：2019-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2007-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2021.110767
更新日期：2021-01-27 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109907
更新日期：2020-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.04.013
更新日期：2016-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.06.041
更新日期：2016-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2008.08.003
更新日期：2008-11-01 00:00:00
abstract：:Residents in close proximity to agricultural land are at risk of higher pesticide exposures. The purpose of this study was to generate national population-level exposure estimates for Canada for three commonly applied pesticides that are suspected carcinogens (2,4-dichlorophenoxyacetic acid (2,4-D), glyphosate and chl...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110100
更新日期：2020-12-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.04.008
更新日期：2014-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110706
更新日期：2021-01-06 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.2001.4317
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Exposure to PM2.5 (fine particulate matter journal_title：Environmental research pub_type： 杂志文章 doi：10.1016/j.envres.2017.11.050 更新日期：2018-02-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2020-08-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2013.08.012
更新日期：2013-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：1986-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.12.017
更新日期：2019-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1997.3812
更新日期：1998-08-01 00:00:00
abstract：INTRODUCTION:Accumulating evidence indicates that arsenic (As), a potent environmental toxicant, may increase cardiovascular disease risk and adversely affect endothelial function at high levels of exposure. Pregnancy is a vulnerable time for both mother and child; however, studies examining the association between pre...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.03.056
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:In utero exposure to dioxins and related compounds have been associated with adverse neurocognitive development in infants. It is unclear whether neurodevelopmental deficits persist to childhood. We assessed the association of prenatal dioxin exposure with neurocognitive function in 11-year-ol...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.06.003
更新日期：2016-10-01 00:00:00
abstract：:The effect of exposure to lead on the longitudinal development of the femur and of its cartilage growth plate was studied in rats. A group of forty-five 50-day-old female Wistar rats was divided into a control group of 20 rats and an experimental group of 25 rats fed a diet supplemented with 17 mg of lead acetate per ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1997.3760
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:According to the WHO, low birth weight (<2500 gr) is a primary maternal health indicator as the cause of multiple morbi-mortality in the short and long-term. It is known that air pollution from road traffic (PM10, NO2) and O3 have an important impact on low birth weight (LBW), but there are few studies of th...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.01.030
更新日期：2019-04-01 00:00:00
