Abstract：
OBJECTIVE:To examine the hypothesis that older hospitalized patients have higher laboratory costs than younger patients in the same severity-adjusted diagnosis-related group (DRG). DESIGN:We obtained hospital case mix data sets (1995-1997) from the Massachusetts Division of Health Care Finance and Policy. We selected discharge abstracts from 4 medical DRGs, at 5 large academic hospitals (n = 15,265) and 5 midsized community hospitals (n = 10,540), for analysis. We converted laboratory and blood product charges to direct costs using the department-specific ratio of cost to charges. We adjusted diagnostic groups for severity of comorbid conditions and complications using the refined DRG method. MAIN OUTCOME MEASURES:Hospital length of stay (LOS), laboratory direct cost (LDC) per hospitalization, LDC per hospital day, and ratio of LDC to total direct cost. RESULTS:Hospital LOS was longer for older patients in all comparisons. Laboratory direct cost per hospitalization was higher for older patients in some DRGs, but lower in other DRGs. Laboratory direct cost per hospital day was almost always less for older patients than for younger patients, both at academic and community hospitals. Data stratification by gender, admission status, and principal diagnosis yielded substantially the same pattern of cost differences observed within the larger data set. CONCLUSIONS:Older medical patients have longer hospital stays and generally higher costs. These patients also have a significantly decreased rate of laboratory resource consumption over the course of hospitalization (LDC per hospital day), as well as lower laboratory costs as a proportion of total costs. Age-specific differences in LOS and cost parameters were essentially unchanged after controlling for several potential sources of bias.
journal_name
Arch Pathol Lab Medjournal_title
Archives of pathology & laboratory medicineauthors
Brimhall BB,Dean T,Hunt EL,Siegrist RB,Reiquam Wdoi
10.1043/0003-9985(2003)127<169:AALCFH>2.0.CO;2subject
Has Abstractpub_date
2003-02-01 00:00:00pages
169-77issue
2eissn
0003-9985issn
1543-2165journal_volume
127pub_type
杂志文章abstract：:We report the cytopathologic, immunocytochemical, histopathologic, and electron microscopic findings of a juxtaglomerular cell tumor that developed in a hypertensive 25-year-old Japanese woman. The symptoms of her disease disappeared after the tumor was resected. To our knowledge, this is the first case report of this...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:Massive hepatic necrosis following exposure to phenytoin and trimethoprim-sulfamethoxazole is a rare occurrence and to the best of our knowledge has not been reported previously. Acute hepatic failure following administration of trimethoprim-sulfamethoxazole has rarely been seen, and only 4 cases have been well docume...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：10.1043/0003-9985(2000)124<1800:AFHFIA>2.0.CO;2
更新日期：2000-12-01 00:00:00
abstract：CONTEXT:Epidermal growth factor receptor (EGFR) mutations have been identified as predictors of response to EGFR tyrosine kinase inhibitors in non-small cell lung cancer. OBJECTIVE:To investigate the relationship of EGFR mutation status to the histologic subtype of adenocarcinoma according to the new International Ass...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.5858/arpa.2013-0376-OA
更新日期：2014-10-01 00:00:00
abstract：CONTEXT:Newborns are often screened prior to discharge for hyperbilirubinemia. Transcutaneous bilirubin analyzers, such as the BiliChek, are promoted as screening tools, but it is unclear whether they also function well as monitoring devices. Newborns on home phototherapy require frequent determinations of serum biliru...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.1043/1543-2165(2008)132[684:EOTBBU]2.0.CO;2
更新日期：2008-04-01 00:00:00
abstract：:A spectrum of changes that range from crypt basophilia through varying degrees of dysplasia and carcinoma in situ have been observed in the flat, nonraised mucosa of the rectum in patient who received pelvic irradiation for carcinoma of the cervix. This case demonstrates (1) the morphological evidence of the relations...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：:Nasal mucosal biopsy specimens encompassing normal and pathological epithelia were obtained from nickel workers, a population with an increased incidence of carcinomas of the respiratory tract. The immunohistochemical detection of keratins was carried out using monoclonal antibodies AE1 and AE3. The antibody AE1 stain...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：:We report a case of silicone-induced endocarditis as a newly recognized complication of transvenous cardiac pacing catheterization. Silicone was found embedded in thrombotic vegetations on the tricuspid valve of a patient who had a long-standing pacing catheter in the right side of his heart. Scanning electron microsc...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:Hyalinized glomeruli in tissue sections those isolated from kidneys of subjected with end-stage and diabetic nephropathies and from aged persons (older than 75 years) were studied by histochemical, immunohistochemical, electron microscopic, and chemical methods. Our purposes were as follows: (1) to clarify the pathoge...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1981-11-01 00:00:00
abstract：:Sarcoidlike granulomas may occur in association with Hodgkin lymphoma and non-Hodgkin lymphoma. The granulomas may be concomitant and so extensive that they obscure the malignant process. In addition, a sarcoidosis-lymphoma syndrome has been described in which there appears to be a relationship between sarcoidosis and...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：10.1043/0003-9985(2000)124<0152:LGBCLA>2.0.CO;2
更新日期：2000-01-01 00:00:00
abstract：:We report the case of a primary breast rhabdomyosarcoma in a 51-year-old white woman. The tumor occupied the upper outer quadrant of the right breast. There was no association with the underlying pectoral muscle, and the patient was free of any other benign or malignant neoplastic processes outside the breast. Microsc...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1998-08-01 00:00:00
abstract：CONTEXT:Advances in RHD genotyping offer an opportunity to update policies and practices for testing weak D phenotypes and administration of Rh immune globulin to postpartum women. OBJECTIVES:To repeat questions from a 1999 College of American Pathologists proficiency test survey, to evaluate current practices for tes...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.5858/arpa.2013-0141-CP
更新日期：2014-05-01 00:00:00
abstract：:We describe a 14-year-old boy with a solitary cavernous hemangioma in the proximal small intestine that caused recalcitrant iron deficiency anemia beginning at 3 years of age. After a number of attempts to ascertain the cause of the anemia were unsuccessful, the vascular tumor was ultimately diagnosed in the jejunum, ...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-01 00:00:00
abstract：:The purpose of this review is to address some common problems involving the diagnosis of trophoblastic lesions. ...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：10.1043/1543-2165(2008)132[168:DPWTL]2.0.CO;2
更新日期：2008-02-01 00:00:00
abstract：CONTEXT:The addition of cetuximab to first-line chemotherapy substantially prolonged survival in patients with advanced non-small cell lung cancer whose tumors expressed high levels of epidermal growth factor receptor (EGFR; immunohistochemistry score of ≥200 on a scale of 0-300). OBJECTIVE:To evaluate the interobserv...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.5858/arpa.2012-0605-OA
更新日期：2013-09-01 00:00:00
abstract：CONTEXT.—:Resection of breast carcinoma with adequate margins reduces the risk of local recurrence and reoperation. Tozuleristide (BLZ-100) is an investigational peptide-fluorophore agent that may aid in intraoperative tumor detection and margin assessment. In this study, fluorescence imaging was conducted ex vivo on g...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.5858/arpa.2018-0197-OA
更新日期：2019-09-01 00:00:00
abstract：:Lymph node involvement by histiocytosis X is usually secondary to nearby bone or skin lesions. A patient with histiocytosis X confined to lymph nodes is rarely seen; however, we studied two such persons. In each, a lymph node biopsy was performed because the clinical aspects caused us to suspect neoplastic disease. ...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1982-02-01 00:00:00
abstract：PROBLEM CONSIDERED:Reproducibility is only one dimension of test quality to be considered when evaluating the utility of a test or deciding to perform a test at or near the point of care. METHODS:Personal experience and review of the literature. RESULTS:Hemoglobin A1c and bedside glucose measurements are cited as exa...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:Epithelioid sarcomas are rare, mesenchymal tumors of unknown histogenesis and display multidirectional differentiation, which is predominantly epithelial. They have no normal cellular counterpart and differ from both synovial sarcoma and carcinoma. They account for less than 1% of all soft tissue sarcomas and are usua...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：10.1043/1543-2165-133.5.814
更新日期：2009-05-01 00:00:00
abstract：:The concentration of neuron-specific enolase (NSE, gamma-subunit of enolase) in tumor extracts of 25 nonargyrophilic and seven argyrophilic carcinomas of the female breast was measured by radioimmunoassay. The mean concentration of NSE in nonargyrophilic carcinomas was 89 ng/mg of protein, (range, 9 to 281 ng/mg), and...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1987-09-01 00:00:00
abstract：:Langerhans cell histiocytosis (LCH) is a neoplastic proliferation of Langerhans cells that occurs in a range of nodal and extranodal sites. Scattered reports of LCH within the thymus exist, typically among children within the setting of multifocal, multisystem disease. Rare cases of isolated LCH involving the thymus h...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：10.1043/1543-2165(2003)127
更新日期：2003-07-01 00:00:00
abstract：:Histiocytes counted in smears made from the tracheobronchial washings of 208 patients with malignant melanomas were found to be 3.12 times more numerous than in a control group comparable in sex, age (decades), and smoking habit but without any type of prediagnosed malignant lesion. The discovery of this phenomenon ma...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1978-12-01 00:00:00
abstract：:A 52-year-old man, suffering for years from malabsorption due to endemic sprue, developed progressive bowel dysfunction, ie, recurrent ileus and intestinal pseudo-obstruction. Because of partial volvulus formation, ileocecal resection was performed. Histopathologic examination of the resected specimen revealed signs o...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Peliotic lesions of the liver and spleen are rare and usually occur in patients with wasting diseases, such as tuberculosis and cancer, or in patients who have received treatment with anabolic-androgenic steroids. Peliosis appears grossly as blood-filled, cyst-like or nodular lesions, 1 to 5 mm in diameter, that are d...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1982-02-01 00:00:00
abstract：:We studied a woman who underwent a jejunoileal bypass for the treatment of morbid obesity and in whom severe jaundice and hepatic failure developed six months later; these developments prompted restoration of the normal continuity of the small bowel. Four serial wedge biopsy specimens of the liver were taken during a ...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1983-04-01 00:00:00
abstract：:We performed x-ray microanalysis of autopsy specimens using a scanning-transmission electron microscopy mode. Tissues were obtained at necropsy from a patient with history of angiography using thorium dioxide and from a patient with hemochromatosis. X-ray microanalysis confirmed the presence of thorium and iron in the...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：CONTEXT:Bone marrow examination is essential for diagnosis and staging of hematologic disorders. Traditionally, the bone marrow biopsy and aspirate are obtained with 2 needles at 2 separate sites. This approach is associated with significant discomfort, procedural time, and occasionally, morbidity. Although previous ob...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.5858/arpa.2012-0046-OA
更新日期：2013-07-01 00:00:00
abstract：:The pathologists and cytologists who study Papanicolaou smears perform a highly successful cancer screening test in a low-prevalence population. This leads to a mathematically inevitable false-negative error rate even in the most competent professional hands. The US judicial system supports a public expectation of per...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1997-03-01 00:00:00
abstract：CONTEXT:-Multiple sources have identified challenges that training programs face in preparing graduates for the "real world" practice of pathology, and many training programs have sought to decrease the gap between skills acquired during training and those required in practice. However, there exists the possibility tha...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.5858/arpa.2015-0138-CP
更新日期：2017-02-01 00:00:00
abstract：:Two hundred twenty-seven arteries from 17 autopsy patients having a history of Kawasaki disease were studied histopathologically and immunohistologically. Forty-five arteries in four cases (duration of illness ranging from 23 to 33 days) showed an arterial lesion characterized by reactive proliferative change of the m...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：:Sclerosing angiomatoid nodular transformation (SANT) is a recently recognized nonneoplastic vascular lesion of the spleen with fewer than 30 cases described. Microscopically, SANT consists of multiple well-circumscribed vascular/angiomatoid nodules showing plump endothelial cell and extravasated erythrocytes. The nodu...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.1043/1543-2165(2007)131[974:SANTOT]2.0.CO;2
更新日期：2007-06-01 00:00:00
