Abstract:
:During the past three to four decades, a significant amount of data was collected to reinforce the notion that mitochondrial function is irrevocably linked to mitochondrial structure. Indeed, data from numerous studies have revealed several salient points of mitochondrial biology that include the following: 1). mitochondria exist as a reticulum rather than as single entities, 2). different mitochondrial populations identified by their cellular location are characterized by different structural and functional characteristics, and 3). muscle mitochondrial respiratory capacity readily adapts to changes in muscle use and disuse by adjusting tissue metabolic capacity to match functional demands. More recently, research in the area of mitochondrial biology has focused on uncovering 1). the cellular signals responsible for the control of mitochondrial biogenesis via coordinate regulation of nuclear and mitochondrial gene expression, 2). the mechanisms by which mitochondrial respiration is regulated, and 3). the role of mitochondria in apoptotic cell death. The most current knowledge in these areas of mitochondrial biology will be addressed in the following symposium papers.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Turcotte LPdoi
10.1097/00005768-200301000-00014subject
Has Abstractpub_date
2003-01-01 00:00:00pages
82-5issue
1eissn
0195-9131issn
1530-0315journal_volume
35pub_type
杂志文章,评审abstract:PURPOSE:Cardiac troponin T (cTnT) is a highly specific marker of myocardial damage and used clinically in the diagnosis of acute myocardial infarction (AMI). Release of cTnT has been demonstrated in several small studies after endurance exercise. The purpose of this study was to explore, using a meta-analytic approach,...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,meta分析
doi:10.1249/mss.0b013e318153ff78
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:Stress-induced cardiovascular reactivity is associated with the pathogenesis of cardiovascular disease. This study tested whether a simulated active commute to school dampened cardiovascular reactivity to a cognitive stressor typical to what children might experience during school. METHODS:Forty children (20 g...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e3181d0c77b
更新日期:2010-08-01 00:00:00
abstract::The objective of the Team Physician Consensus Statement is to provide physicians, school administrators, team owners, the general public, and individuals who are responsible for making decisions regarding the medical care of athletes and teams with guidelines for choosing a qualified team physician and an outline of t...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200004000-00023
更新日期:2000-04-01 00:00:00
abstract::The purpose of this study was to describe the body composition of adolescent and young adult ballet dancers using total body electrical conductivity (TOBEC). We studied 112 female and 33 male dancers. The mean ages were 15.0 +/- 2.0 and 18.7 +/- 3.1 yr for females and males, respectively. The mean percent body fat (PB...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:PURPOSE:beta2 adrenergic agonists are widely used as doping agents. Their side effects on bone, especially microarchitecture, remain unknown. The purpose of this study was to evaluate the effects of chronic clenbuterol and salbutamol treatment on bones of growing rats. METHODS:Twelve-week-old Wistar female rats were d...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000177592.82507.95
更新日期:2005-09-01 00:00:00
abstract::The effects of supervised physical training (PT) and lifestyle education (LSE) on risk factors for coronary artery disease and non-insulin-dependent diabetes mellitus were compared in obese 7- to 11-yr-old black girls. The subjects were divided into two groups. The PT group (N = 12) completed a 5-d.wk-1, 10-wk, aerobi...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1097/00005768-199601000-00009
更新日期:1996-01-01 00:00:00
abstract::The performance of the Caltrac accelerometer was studied in elementary school-age children under field and laboratory conditions. In Study 1, 35 children (20 boys, 15 girls, mean age = 10.8 yr) wore the accelerometer and a heart rate (HR) monitor for 2 d. Caltrac activity counts per hour were compared to the mean "act...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-199010000-00023
更新日期:1990-10-01 00:00:00
abstract:PURPOSE:The purpose of this study is to examine whether performance supercompensation during taper is maximized in endurance athletes after experiencing overreaching during an overload training (OT) period. METHODS:Thirty-three trained male triathletes were assigned to either OT (n = 23) or normal training groups (n =...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000301
更新日期:2014-09-01 00:00:00
abstract::Since many physiological, metabolic, and endocrine changes that occur during pregnancy are evident even at rest, the alterations found during exercise may not necessarily be the same as those found in the normal population. Nonetheless, the exercise-induced cardiopulmonary changes are essentially normal or slightly ex...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/00005768-198508000-00001
更新日期:1985-08-01 00:00:00
abstract:PURPOSE:In this study, we examined the effects of body position (from deep to high position) in slide boarding by well-trained cross-country skiers. The main hypothesis was that a deeper, more "crouched" position would lead to reduced air resistance and enhanced power production during explosive extension of the lower ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000227536.13175.52
更新日期:2006-08-01 00:00:00
abstract:PURPOSE:Sitting time (ST) is a serious global health issue and positively associated with cardiometabolic disease. The present study investigated associations between objectively measured ST, sedentary patterns, and cardiometabolic biomarkers in physically active young males. METHODS:Cross-sectional analysis was compl...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002528
更新日期:2020-10-01 00:00:00
abstract::The field of developmental neurobiology is entering a very exciting phase, in which the application of new techniques promises to lead to major advances in our understanding of basic developmental processes. There is a need to apply much of this new knowledge to problems of spinal cord and muscle development, about wh...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1985-02-01 00:00:00
abstract:INTRODUCTION:We examined the relationships between insulin-like growth factor I (IGF-I), its binding protein (IGFBP-3), body composition, and bone mineral density (BMD) in collegiate runners (N = 13), gymnasts (N = 10), and noncompetitive women (N = 10). METHODS:Subjects were evaluated by dual-energy x-ray absorptiome...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200011000-00013
更新日期:2000-11-01 00:00:00
abstract::We develop an observation system that quantifies the duration, intensity, and frequency of children's physical activities. We use this system to assess the level and tempo of energy expenditure under free-ranging, natural conditions experienced by 15 children aged 6-10 yr in southern California. Observations were reco...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-199507000-00012
更新日期:1995-07-01 00:00:00
abstract::The effect of physical exercise and vitamin C on iron absorption after oral iron administration was investigated. Eight healthy male subjects without iron deficiency were studied after administration of 100 mg ferric sodium citrate complex, 100 mg ferric sodium citrate complex with 200 mg ascorbic acid, and without ir...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:10.1097/00005768-199612000-00005
更新日期:1996-12-01 00:00:00
abstract::Inappropriate cushioning and/or tractional characteristics of sports surfaces are assumed to increase surface-related injuries in various sports activities. Various tests assessing cushioning and frictional properties are currently in use to evaluate sports surfaces with respect to their potential to reduce the number...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1990-02-01 00:00:00
abstract:PURPOSE:The purpose of this study was to compare the predictive accuracy of previously published skinfold (SKF) equations for estimating body density of 134 premenopausal African-American women (18 to 40 yr). METHODS:The equations cross-validated were: the sum of seven skinfolds equation (JPW7) and the sum of three sk...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199811000-00015
更新日期:1998-11-01 00:00:00
abstract:PURPOSE:The objective of this study is to investigate the effect of three different workplace interventions on long-term compliance, muscle strength gains, and neck/shoulder pain in office workers. METHODS:A 1-yr randomized controlled intervention trial was done with three groups: specific resistance training (SRT, n ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e3181676640
更新日期:2008-06-01 00:00:00
abstract::Healthy men (N = 33) and women (N = 73) participated in a 6-month exercise program three mornings per week, and their attendance scores (percent of total classes attended) were related to a variety of physiological, anthropometric, psychological, and demographic variables which were studied. These subjects were also g...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1984-12-01 00:00:00
abstract:PURPOSE:High school cross-country runners have a high incidence of injury, particularly at the shin and knee. An increased step rate during running has been shown to reduce impact forces and loading of the lower extremity joints. The purpose of this prospective study was to examine step rate as a risk factor for injury...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000000890
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To determine substrate utilization and energy expenditure during maximal and submaximal exercise and recovery in adolescents with cystic fibrosis (CF) and healthy age-matched controls (C). METHODS:Ten clinically stable CF patients (four girls, six boys; age = 10-22 yr) were matched by body mass index, age, gen...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e318188449b
更新日期:2009-02-01 00:00:00
abstract:PURPOSE:This study examined whether plasma total glutathione levels could explain the intersubject variability in the creatine kinase (CK) response to eccentric exercise. We hypothesized that the increase in plasma CK activity after eccentric exercise would be lower for individuals with low plasma total glutathione (<2...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000069553.47739.36
更新日期:2003-06-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the physiological and performance responses to a simulated freestyle wrestling tournament after typical weight loss techniques used by amateur wrestlers. METHODS:Twelve Division I collegiate wrestlers (mean +/- SD;19.33 +/- 1.16 yr) lost 6% of total body weight duri...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200108000-00019
更新日期:2001-08-01 00:00:00
abstract::The reproducibility of the Bruce exercise test protocol for the determination of maximal aerobic activity was evaluated in sedentary older women. Seventeen women between the ages of 51 and 68 yr performed five maximal graded exercise tests to volitional fatigue on a treadmill. VO2max (mL.kg-1.min-1) values averaged 27...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199708000-00018
更新日期:1997-08-01 00:00:00
abstract::To compare the physiological response to a cocaine-exercise challenge in cocaine-conditioned animals with that of acute-cocaine animals, rats were injected i.p. with either cocaine (20 mg.kg-1) or saline, twice daily for 14 consecutive days. On the 15th day (test day) cocaine-conditioned rats received an i.v. injectio...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Sprint-trained athletes demonstrate a remarkable ability to perform exercise which results in fatigue quickly. However, the mechanisms for these enhanced performance capabilities have not been fully elucidated. Elevation in glycolytic enzymes and increased fast-twitch fiber compositions which would result in an enhanc...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:
更新日期:1984-08-01 00:00:00
abstract:PURPOSE:We asked whether submaximal exercise with chest wall restriction (CWR), as a model of restrictive pulmonary disease, would result in fatigue of the diaphragm in healthy humans. METHODS:To address this question, we used cervical magnetic stimulation of the phrenic nerves along with measures of transdiaphragmati...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3181ef5e67
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:This study aimed to quantify the frequency, magnitude, and location of head impacts sustained by male and female collegiate ice hockey players during two seasons of play. METHODS:During two seasons, 88 collegiate athletes (51 females, 37 males) on two female and male National Collegiate Athletic Association va...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e31822b0ab4
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:One approach to studying the effects of aging on physiological functional capacity (PFC) in humans is to analyze the peak physical performance of trained athletes with increasing age. The primary aim of the present study was to determine weightlifting and powerlifting performance with increasing age in both men...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000106283.34742.BE
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:The effect of quantified resistance and high impact exercise training on bone mass as modified by age and oral contraceptive (OCont) use in young women was studied. METHODS:Women were categorized by age (18-23 vs 24-31 yr) and OCont use, and were then randomized into either three sessions of resistance exercis...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200106000-00004
更新日期:2001-06-01 00:00:00