Progression of lower-extremity disability in older women with diabetes: the Women's Health and Aging Study.

abstract：OBJECTIVE:Growth deferentiation factor-15 (GDF-15) is involved in inflammation and apoptosis. Expression is induced in the heart in response to ischemia and in atherosclerotic plaques. The aim of this study was to investigate GDF-15 levels in relation to all-cause mortality, cardiovascular mortality and morbidity, decl...

journal_title：Diabetes care

authors： Lajer M,Jorsal A,Tarnow L,Parving HH,Rossing P

更新日期：2010-07-01 00:00:00

abstract：:The acute effect of sulfonylurea drugs during long-term treatment was evaluated in two separate studies. In the first study, the levels of plasma glucose, insulin, and C-peptide were measured after intake of 10 mg glyburide alone or together with a standardized mixed meal in 10 non-insulin-dependent diabetes mellitus ...

journal_title：Diabetes care

authors： Faber OK,Beck-Nielsen H,Binder C,Butzer P,Damsgaard EM,Froland F,Hjollund E,Lindskov HO,Melander A,Pedersen O

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:In vitro evidence shows that immune function is compromised in people with diabetes. Although certain rare infections are more common and infection-related mortality is higher, the risk of acquiring an infectious disease for diabetic patients has never been quantified. RESEARCH DESIGN AND METHODS:A retrospec...

journal_title：Diabetes care

authors： Shah BR,Hux JE

更新日期：2003-02-01 00:00:00

abstract：:The reality of primary and secondary prevention of cardiovascular complications in people with diabetes is alarming, even in developed countries with a well-structured medical system. Even though therapeutic targets have been more clearly defined during the last decades, their implementation is still suboptimal. Finan...

journal_title：Diabetes care

authors： Stirban AO,Tschoepe D

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Recent studies suggest that air pollution plays a role in type 2 diabetes (T2D) incidence and mortality. The underlying physiological mechanisms have yet to be established. We hypothesized that air pollution adversely affects insulin sensitivity and secretion and serum lipid levels. RESEARCH DESIGN AND METHO...

journal_title：Diabetes care

authors： Chen Z,Salam MT,Toledo-Corral C,Watanabe RM,Xiang AH,Buchanan TA,Habre R,Bastain TM,Lurmann F,Wilson JP,Trigo E,Gilliland FD

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:We examined the association between high blood pressure and incident type 2 diabetes in African Americans and whites aged 35-54 years at baseline. RESEARCH DESIGN AND METHODS:We combined data from the Atherosclerosis Risk in Communities (ARIC) study, the Coronary Artery Risk Development in Young Adults (CARD...

journal_title：Diabetes care

authors： Wei GS,Coady SA,Goff DC Jr,Brancati FL,Levy D,Selvin E,Vasan RS,Fox CS

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To determine the association between serum 25-hydroxyvitamin D (25OHD) and diabetes risk and whether it varies by ethnicity. RESEARCH DESIGN AND METHODS:We performed an analysis of data from participants who attended the morning examination of the Third National Health and Nutrition Examination Survey (1988-...

journal_title：Diabetes care

authors： Scragg R,Sowers M,Bell C,Third National Health and Nutrition Examination Survey.

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of hypoglycemia in patients with type I diabetes and impaired awareness of hypoglycemia by prospective assessment. RESEARCH DESIGN AND METHODS:A prospective study was undertaken for 12 months in 60 patients with type I diabetes: 29 had impaired awareness of hypoglycemia and 31 reta...

journal_title：Diabetes care

authors： Gold AE,MacLeod KM,Frier BM

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of diabetes in Tohono O'odham pregnancies, and to assess the efficacy of early prenatal diabetes screening in populations with high rates of diabetes. RESEARCH DESIGN AND METHODS:All Tohono O'odham women receiving prenatal care at the Sells Service Unit who delivered a viable baby...

journal_title：Diabetes care

authors： Livingston RC,Bachman-Carter K,Frank C,Mason WB

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To compare the glucose variability associated with insulin glargine and NPH/Lente insulin used as the basal insulin component of a multiple daily injection (MDI) regimen in pediatric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Continuous glucose monitoring data were collected from a subset of ...

journal_title：Diabetes care

authors： White NH,Chase HP,Arslanian S,Tamborlane WV,4030 Study Group.

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To compare pharmacokinetics (PK) and pharmacodynamics (PD) of insulin glargine in type 2 diabetes mellitus (T2DM) after evening versus morning administration. RESEARCH DESIGN AND METHODS:Ten T2DM insulin-treated persons were studied during 24-h euglycemic glucose clamp, after glargine injection (0.4 units/kg...

journal_title：Diabetes care

authors： Porcellati F,Lucidi P,Cioli P,Candeloro P,Marinelli Andreoli A,Marzotti S,Ambrogi M,Bolli GB,Fanelli CG

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:Some children with type 1 diabetes may be at risk of cognitive impairments, but mechanisms of this effect have not been confirmed. The objective of this study was to determine whether severe hypoglycemia (SH) in children with type 1 diabetes is associated with cognitive decline over 18 months. RESEARCH DESIG...

journal_title：Diabetes care

authors： Wysocki T,Harris MA,Mauras N,Fox L,Taylor A,Jackson SC,White NH

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Early use of insulin after diagnosis of type 2 diabetes is met with resistance because of associated weight gain, hypoglycemia, and fear of decreased compliance and quality of life (QoL). RESEARCH DESIGN AND METHODS:In treatment-naive patients with newly diagnosed type 2 diabetes, insulin and metformin were ...

journal_title：Diabetes care

authors： Lingvay I,Legendre JL,Kaloyanova PF,Zhang S,Adams-Huet B,Raskin P

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Reports of amputations associated with sodium-glucose cotransporter 2 (SGLT2) inhibitors have been inconsistent. We aimed to compare the risk of below-knee amputation with SGLT2 inhibitors versus dipeptidyl peptidase 4 (DPP-4) inhibitors among patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:This m...

journal_title：Diabetes care

authors： Yu OHY,Dell'Aniello S,Shah BR,Brunetti VC,Daigle JM,Fralick M,Douros A,Hu N,Alessi-Severini S,Fisher A,Bugden SC,Ronksley PE,Filion KB,Ernst P,Lix LM,Canadian Network for Observational Drug Effect Studies (CNODES) Investiga

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To examine whether cardiovascular autonomic neuropathy (CAN) is an independent risk factor of cardiovascular disease (CVD) events during DCCT/EDIC. RESEARCH DESIGN AND METHODS:Standardized cardiovascular autonomic reflex tests (R-R response to paced breathing, Valsalva maneuver, postural changes in blood pre...

journal_title：Diabetes care

authors： Pop-Busui R,Braffett BH,Zinman B,Martin C,White NH,Herman WH,Genuth S,Gubitosi-Klug R,DCCT\/EDIC Research Group.

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To assess the contemporaneous prevalence of diabetic peripheral neuropathy (DPN) in people with type 1 diabetes (T1D) in Scotland and study its cross-sectional association with risk factors and other diabetic complications. RESEARCH DESIGN AND METHODS:We analyzed data from a large representative sample of ad...

journal_title：Diabetes care

authors： Jeyam A,McGurnaghan SJ,Blackbourn LAK,McKnight JM,Green F,Collier A,McKeigue PM,Colhoun HM,SDRNT1BIO Investigators.

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To assess the long-term cost-effectiveness of aspirin use among adults aged >or=40 years with newly diagnosed type 2 diabetes. RESEARCH DESIGN AND METHODS:We used a validated cost-effectiveness model of type 2 diabetes to assess the lifetime health and cost consequences of use or nonuse of aspirin. The model...

journal_title：Diabetes care

authors： Li R,Zhang P,Barker LE,Hoerger TJ

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:The goal of the study was to examine risk factors in the prediction of coronary heart disease (CHD) and differences in men and women in the EURODIAB Prospective Complications Study. RESEARCH DESIGN AND METHODS:Baseline risk factors and CHD at follow-up were assessed in 2,329 type 1 diabetic patients without ...

journal_title：Diabetes care

authors： Soedamah-Muthu SS,Chaturvedi N,Toeller M,Ferriss B,Reboldi P,Michel G,Manes C,Fuller JH,EURODIAB Prospective Complications Study Group.

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To provide an overview of the Department of Veterans Affairs (VA) research activities, highlighting diabetes-related research. RESEARCH DESIGN AND METHODS:Diabetes is an important component of the VA research portfolio. All four VA research services support aspects of diabetes research. VA diabetes research ...

journal_title：Diabetes care

authors： Reiber GE,Boyko EJ

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Studies showing that family communication and conflict resolution are critical to effective management of type 1 diabetes in adolescents have stimulated interest in evaluating psychological treatments targeting these processes. Previous trials have shown that Behavioral Family Systems Therapy (BFST) improved ...

journal_title：Diabetes care

authors： Wysocki T,Harris MA,Buckloh LM,Mertlich D,Lochrie AS,Mauras N,White NH

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To evaluate safety and efficacy of DiaPep277 in preserving β-cell function in type 1 diabetic patients. RESEARCH DESIGN AND METHODS:DIA-AID 1 is a multinational, phase 3, balanced-randomized, double-blind, placebo-controlled, parallel-group clinical study. Newly diagnosed patients (N = 457, aged 16-45 years)...

journal_title：Diabetes care

authors： Raz I,Ziegler AG,Linn T,Schernthaner G,Bonnici F,Distiller LA,Giordano C,Giorgino F,de Vries L,Mauricio D,Procházka V,Wainstein J,Elias D,Avron A,Tamir M,Eren R,Peled D,Dagan S,Cohen IR,Pozzilli P,DIA-AID 1 Writin

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Determine the impact of islet transplantation on carotid intima-media thickness (CIMT), a marker for atherosclerosis, in type 1 diabetes without kidney disease. RESEARCH DESIGN AND METHODS:Consecutive case series of 15 adults (mean age [SD], 49 years [10 years]; 87% female) with type 1 diabetes for ≥5 years ...

journal_title：Diabetes care

authors： Danielson KK,Hatipoglu B,Kinzer K,Kaplan B,Martellotto J,Qi M,Mele A,Benedetti E,Oberholzer J

更新日期：2013-02-01 00:00:00

abstract：:Chemical test strips for estimating blood glucose have been shown to be reliable, rapid, and convenient when properly used. This study compares a new product, the Ames Visidex (Miles Laboratories, Elkhart, Indiana), and an established product, the Bio-Dynamics Chemstrip bG (Boehringer-Mannheim, Indianapolis, Indiana) ...

journal_title：Diabetes care

authors： Frindik JP,Kassner DA,Pirkle DA,Kemp SF,Hoff C

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:This study was performed to determine the net effects of euglycemia, resolution of renal failure, immunosuppressant drugs, and hyperinsulinemia on fasting lipid profiles of patients with renal failure and insulin-dependent diabetes mellitus (IDDM) after combined pancreas-kidney transplantation (PKT). RESEARC...

journal_title：Diabetes care

authors： Larsen JL,Stratta RJ,Ozaki CF,Taylor RJ,Miller SA,Duckworth WC

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To examine the effect of pioglitazone on myocardial insulin sensitivity and left ventricular (LV) function in patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS:Twelve subjects with T2D and 12 with normal glucose tolerance received a euglycemic insulin clamp. Myocardial glucose uptake (MGU) and...

journal_title：Diabetes care

authors： Clarke GD,Solis-Herrera C,Molina-Wilkins M,Martinez S,Merovci A,Cersosimo E,Chilton RJ,Iozzo P,Gastaldelli A,Abdul-Ghani M,DeFronzo RA

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the short-term impact of a 7-h type 2 diabetes continuing medical education (CME) program. Outcomes included a measure of health care providers' diabetes knowledge and the Diabetes Attitude Scale (DAS), a validated measure of attitudes toward diabetes. RESEARCH DES...

journal_title：Diabetes care

authors： Sharp LK,Lipsky MS

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Identifying maturity-onset diabetes of the young (MODY) in pediatric populations close to diabetes diagnosis is difficult. Misdiagnosis and unnecessary insulin treatment are common. We aimed to identify the discriminatory clinical features at diabetes diagnosis of patients with glucokinase (GCK), hepatocyte n...

journal_title：Diabetes care

authors： Carlsson A,Shepherd M,Ellard S,Weedon M,Lernmark Å,Forsander G,Colclough K,Brahimi Q,Valtonen-Andre C,Ivarsson SA,Elding Larsson H,Samuelsson U,Örtqvist E,Groop L,Ludvigsson J,Marcus C,Hattersley AT

更新日期：2020-01-01 00:00:00

abstract：:Stress is a potential contributor to chronic hyperglycemia in diabetes. Stress has long been shown to have major effects on metabolic activity. Energy mobilization is a primary result of the fight or flight response. Stress stimulates the release of various hormones, which can result in elevated blood glucose levels. ...

journal_title：Diabetes care

authors： Surwit RS,Schneider MS,Feinglos MN

更新日期：1992-10-01 00:00:00

abstract：:We have examined insulin and glucagon degrading activities of muscle and fat tissues in 11 subjects (4 lean controls, 3 insulin-resistant obese subjects, 2 non-insulin-dependent diabetic subjects, and 2 insulin-treated diabetic subjects) and correlated degrading activity with (1) basal insulin level and (2) state of i...

journal_title：Diabetes care

authors： Kitabchi AE,Stentz FB,Cole C,Duckworth WC

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine medication adherence and other self-management practices as potential determinants of higher glycemic risk among black relative to white patients. RESEARCH DESIGN AND METHODS:We used a retrospective, longitudinal repeated-measures design to model the contribution of m...

journal_title：Diabetes care

authors： Adams AS,Trinacty CM,Zhang F,Kleinman K,Grant RW,Meigs JB,Soumerai SB,Ross-Degnan D

更新日期：2008-05-01 00:00:00