Abstract：
:Biomphalaria glabrataembryonic (Bge) cells have been shown to provide favourable environmental conditions for the development of Schistosoma mansoni sporocysts. We investigated the effect of Bge excretory-secretory products on metabolic activity and gene transcription in S. mansoni mother sporocysts. Using the differential-display technique, we identified several sporocyst transcripts regulated by exposure to Bge soluble components. Research in databases indicated that six of the eight differential products analysed were homologous to sequences already present in databases. Two transcripts appeared of interest for schistosome development since they could be associated with cell division and protein synthesis in developing sporocysts. Their up-regulation following contact with cell products was confirmed by semi-quantitative RT-PCR. The first fragment coded for a part of the chaperonin containing T-complex protein gamma subunit-like protein of S. mansoni (SmTCP 1-C). The second one represented a new S. mansoni expressed sequence tag encoding a protein homologous to various glutaminyl-tRNA synthetases (GlnRS). The full-length sequence of SmGlnRS was cloned from adult schistosomes and its primary sequence was compared to other GlnRS. The overexpression of SmTCP-1 and SmGlnRS could be correlated with the metabolic changes observed in Bge-exposed sporocysts.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Coppin JF,Lefebvre C,Caby S,Cocquerelle C,Vicogne J,Coustau C,Dissous Cdoi
10.1007/s00436-002-0643-2subject
Has Abstractpub_date
2003-01-01 00:00:00pages
113-9issue
2eissn
0932-0113issn
1432-1955journal_volume
89pub_type
杂志文章abstract：:Differentiation between viable and non-viable hookworm ova in environmental samples is necessary in order to implement strategies to mitigate re-infections in endemic regions. In this study, an untargeted metabolic profiling method was developed that utilised gas chromatography-mass spectrometry (GC-MS) in order to in...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5112-4
更新日期：2016-09-01 00:00:00
abstract：:Trichinella spiralis infection results in the transformation of muscle cells into a new, non-muscular cell called the nurse cell, and the nurse cell-muscle larva complex is finally created. To investigate whether T. spiralis infectivity is NBL age-dependent, five groups of synchronous newborn larvae (sNBL) were obtain...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050550
更新日期：1999-04-01 00:00:00
abstract：:Feline lungworms infect the respiratory tract of wild and domestic cats, causing infection often associated with clinical disease. Until recently, Aelurostrongylus abstrusus has been considered the most relevant species of lungworm, while Troglostrongylus brevior was considered of less significance. Fecal samples of f...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06852-8
更新日期：2020-10-01 00:00:00
abstract：:Levamisole phosphate, chosen based on its 100 % efficacy demonstrated by a previous fecal egg count reduction test (FECRT), was used as the exclusive anthelmintic treatment in the Embrapa Southeast Livestock sheep flock from 2009 to 2014 in a target selected treatment scheme. In the present study, the effectiveness of...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4844-x
更新日期：2016-03-01 00:00:00
abstract：:We developed a real-time LC PCR assay to detect a 152 bp sequence in an uncharacterized region of the Blastocystis genome. The described assay detected 11 of 11 ATCC strains of Blastocystis from subtypes 1, 3, and 4. Three of three stool samples from Oregon and California military personnel that were negative for Blas...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1006-4
更新日期：2008-08-01 00:00:00
abstract：:An endopeptidase specific to the Plasmodium falciparum erythrocytic schizont stage and to free merozoites was detected using the fluorogenic GlcA-Val-Leu-Gly-Lys(or Arg)-AEC substrate. The enzyme was purified by high performance liquid chromatography (HPLC); its optimal activity was around pH 7.5 and its isoelectric p...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00930972
更新日期：1989-01-01 00:00:00
abstract：:Leishmania (L.) tropica is a causative agent of cutaneous and occasionally visceral or viscerotropic leishmaniasis in humans. The dose of parasites influences the course and outcome of disease in some Leishmania species. The effect of parasite dose on L. tropica infection in an experimental model was studied in the cu...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5991-7
更新日期：2018-09-01 00:00:00
abstract：:Sarcocystis neurona is the parasite associated with equine protozoal myeloencephalitis (EPM). Recently, cats (Felis domesticus) have been implicated as a potential intermediate host in the life cycle of S. neurona. This study was initiated to determine whether cats have antibodies that react to S. neurona antigens sim...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360100503
更新日期：2002-01-01 00:00:00
abstract：:Several murine monoclonal antibodies were raised against purified soluble Plasmodium falciparum antigens from the asexual blood stage. The monoclonal antibodies were purified from ascites by preparative agarose gel electrophoresis and tested for inhibitory activities against P. falciparum in vitro cultures. One monocl...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00535326
更新日期：1987-01-01 00:00:00
abstract：:The efficacy of metaphylactic treatment with toltrazuril (Baycox 5% suspension) against natural infections with Eimeria bovis and/or Eimeria zuernii in calves was investigated. The study was conducted with 208 calves on five calf-rearing farms in Germany and the Czech Republic. All participating farms had a notable in...
journal_title：Parasitology research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00436-005-1457-9
更新日期：2005-10-01 00:00:00
abstract：:An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of Echinococcus coproantigens in fecal samples from dogs, dingoes or foxes infected with either E. granulosus or E. multilocularis. The ELISA was based on protein-A-purified polyclonal antibodies [anti-E. granulosus excretory/secretory (E/S) ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00937088
更新日期：1992-01-01 00:00:00
abstract：:During their different life stages, parasites undergo remarkable morphological, physiological, and behavioral "metamorphoses" to meet the needs of their changing habitats. This is even true for ectoparasites, such as the monogeneans, which typically have a free-swimming larval stage (oncomiracidium) that seeks out and...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-07045-z
更新日期：2021-01-12 00:00:00
abstract：:Systematic, continuous mosquito surveillance is considered the most reliable tool to predict the spread and establishment of alien mosquito species such as the Asian tiger mosquito (Aedes albopictus), Japanese bush mosquito (Aedes japonicus), and the transmission risk of mosquito-borne arboviruses to humans. Only sing...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06287-w
更新日期：2019-05-01 00:00:00
abstract：:Neurocysticercosis (NC) is one of the most important diseases caused by parasites affecting the central nervous system. We fractionated by ion-exchange chromatography using diethylaminoethyl (DEAE)-sepharose resin the total saline extract (S) from Taenia solium metacestodes and evaluated obtained fractions (DEAE S1 an...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3908-7
更新日期：2014-07-01 00:00:00
abstract：:Many factors contribute to parasites varying in host specificity and distribution among potential hosts. Metagonimoides oregonensis is a digenetic trematode that uses stream-dwelling plethodontid salamanders as second intermediate hosts in the Eastern US. We completed a field survey to identify which stream salamander...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4550-8
更新日期：2015-08-01 00:00:00
abstract：:Nested PCR was used as a diagnostic tool to investigate the presence of Echinococcus multilocularis tapeworm in protected species of carnivores in Slovakia. Twenty-three faecal samples from wolves, four samples from bears and three samples from lynx from the Muránska Planina mountains and eight samples from wolves fro...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360100452
更新日期：2001-10-01 00:00:00
abstract：:Cyclospora cayetanensis was identified as the cause of large outbreaks of diarrhea in many parts of the world, but its host range and reservoirs remains poorly defined. Recently, oocysts resembling the C. cayetanensis were detected in dairy cattle fecal specimens from China. The 18S rDNA from two of these Cyclospora-l...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0380-z
更新日期：2007-04-01 00:00:00
abstract：:Naturally occurring bithyniid snails, Bithynia siamensis goniomphalos (Prosobranchia: Bithyniidae), and their intermediate hosts were sampled from Khammouane Province, the Lao People's Democratic Republic, and the prevalence of the carcinogenic human liver fluke, Opisthorchis viverrini, was examined. The presence of O...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-2140-3
更新日期：2011-04-01 00:00:00
abstract：:Tetracapsuloides bryosalmonae (Myxozoa) is the causative agent of proliferative kidney disease in various species of salmonids which are found in Europe and North America. Less information about the interactions of T. bryosalmonae proteins with salmonid proteins during parasite development is known. In this study, ant...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4357-7
更新日期：2015-05-01 00:00:00
abstract：:cDNA clones for homologues of a molecular chaperone of the endoplasmic reticulum called the immunoglobulin heavy-chain binding protein (BiP) have been isolated from Eimeria maxima and E. tenella sporozoite cDNA libraries. The E. tenella cDNA clone is of full length and has a predicted N-terminal signal sequence of app...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050163
更新日期：1996-01-01 00:00:00
abstract：:Experimental infection trails of Lymnaea (cailliaudi) natalensis snails with miracidia of Fasciola hepatica revealed neither cercariae nor larval stages shed. Infection of white mice with metacercariae from field-collected snails proved to be negative for Fasciola eggs and immature juveniles or adults after 84 days po...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-0888-5
更新日期：2008-05-01 00:00:00
abstract：:Trichomonas vaginalis, a flagellated protozoan parasite causes a variety of adverse health consequences in both men and women. The parasite exists in the trophozoite and the pseudocystic stage. The study reports for the first time that pseudocyst forms of T. vaginalis isolated from cervical neoplasia (CN) patients dem...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-2848-3
更新日期：2012-07-01 00:00:00
abstract：:Strongyloides stercoralis can cause severe infection both in humans and dogs. Coproparasitological examination has low sensitivity for the diagnosis of this parasite; hence, different diagnostic techniques have been implemented. However, serology and molecular methods have been assessed almost exclusively in humans. I...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5468-0
更新日期：2017-07-01 00:00:00
abstract：:This randomised controlled laboratory study demonstrated the residual speed of efficacy of an imidacloprid/flumethrin collar (Seresto(®), Bayer) for the control of ticks (Dermacentor variabilis, Amblyomma americanum) at 6 and 12 hours postinfestation on dogs when compared to oral afoxolaner (NexGard(®), Merial). Dogs ...
journal_title：Parasitology research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00436-015-4515-y
更新日期：2015-08-01 00:00:00
abstract：:Cryptosporidium spp. are common intestinal protozoa causing diarrhea in humans and a variety of animal species. With the recent development of fur industry, a large number of fur animals are farmed worldwide, especially in China. The existence of identical Cryptosporidium species/genotypes in humans and fur animals su...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5686-5
更新日期：2018-01-01 00:00:00
abstract：:Leishmania has distinct epidemiological and biological characteristics and causes a variety of clinical symptoms. To understand the genetic diversity and the phylogenetic relationships among Leishmania isolates from China, 29 Leishmania isolates from different geographic origins, vectors, and hosts were analyzed using...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-1814-1
更新日期：2010-05-01 00:00:00
abstract：:Members of the Naegleria genus are free-living amoebae, and the only pathogenic specie described to date for humans is N. fowleri. However, as the complete genome of this specie has not been reported, non-pathogenic N. gruberi is employed to describe molecular pathways in N. fowleri. Regardless, certain mechanisms, su...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5293-x
更新日期：2017-01-01 00:00:00
abstract：:Isometamidium chloride (ISM) is an effective trypanocide with curative and prophylactive activity in husbandry animals. The mode of action of ISM against pathogenic trypanosomes is not fully understood, but there is evidence in the literature that kinetoplastic topoisomerase type II is selectively inhibited by the dru...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050346
更新日期：1997-01-01 00:00:00
abstract：:The catalysis of malate dehydrogenase (MDH) in Plasmodium falciparum (pfMDH) which involves NAD/NADH coupling is crucial for the parasite's pathogenicity. Primers were designed based on the P. falciparum genome resource, and these facilitated the cloning of a gene coding for pfMDH from a local clinical isolate. The DN...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-003-0996-1
更新日期：2004-01-01 00:00:00
abstract：:Haematophagous leeches express a broad variety of bioactive factors that are released from the salivary gland cells into the wound of a host during feeding. Among these, hirudin is probably the best studied factor and, moreover, the only one that has successfully made the transition from nature to clinical use. Many c...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5294-9
更新日期：2017-01-01 00:00:00
