Abstract:
BACKGROUND:Cannabis is a possible risk factor for the onset of schizophrenia and can induce neurocognitive, behavioural and motor co-ordination alterations. The aim of this study was to evaluate the role of cannabis in the occurrence of neurological soft signs (NSS) and, considering that this drug has been related to positive symptoms, whereas NSS have been linked to negative symptoms, we also examined the role of clinical features. METHODS:The study investigated NSS in 25 male cannabis-consuming and 25 male non-consuming schizophrenic patients, using the Neurological Evaluation Scale. Clinical features were studied using SANS and SAPS. RESULTS:Significant differences emerged after comparison analysis, with more NSS in non-consuming patients. The SANS subscales Alogia and Anhedonia-asociality were also statistically significant in this group of patients. DISCUSSION:If non-consuming patients show a higher incidence of both NSS and negative symptoms, which, according to the literature, seem to be associated, then these findings suggest that NSS are relatively independent from cannabis, but not from clinical features.
journal_name
Psychopathologyjournal_title
Psychopathologyauthors
Bersani G,Orlandi V,Gherardelli S,Pancheri Pdoi
10.1159/000067064subject
Has Abstractpub_date
2002-09-01 00:00:00pages
289-95issue
5eissn
0254-4962issn
1423-033Xpii
67064journal_volume
35pub_type
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