Abstract：
:We assessed the cellular immunological responses to two Plasmodium falciparum liver-stage antigen (LSA)-1-derived T-cell epitopes in healthy Gabonese children and adults. The N-terminal peptide, designated T1, induced interferon (IFN)-gamma production in peripheral blood mononuclear cells (PBMC) from a significantly lower proportion of children compared to adults, but both interleukin (IL)-10 and IL-12 were produced by similar proportions of PBMC from the two groups. The LSA-1 junction region peptide (LSA-J) also induced IFN-gamma in a lower, but in this case statistically non-significant, proportion of PBMC from children compared to adults, whilst the proportions producing either IL-10 or IL-12 were again similar. Higher amounts of both IFN-gamma and IL-10 were induced by LSA-J compared to T1. CD8+ T-cells were shown to be primarily responsible for the production of peptide-driven IFN-gamma. The results suggest a significant age-related increase in the proportion of individuals capable of producing IFN-gamma to the N-terminal T1 epitope, with a shift from a predominantly IL-10-led response in children.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Bongartz M,Rezbach P,Borrmann S,Hollingdale MR,Kremsner PG,Luty AJdoi
10.1007/s00436-002-0703-7subject
Has Abstractpub_date
2002-12-01 00:00:00pages
1083-9issue
12eissn
0932-0113issn
1432-1955journal_volume
88pub_type
杂志文章abstract：:Two thousand four hundred fifty-eight fish comprised of 53 species were captured in the Danjiangkou Reservoir, in the northwestern part of Hubei Province, central China during 2004, to examine Camallanus cotti infections. We found that 19 cypriniform, 3 siluriforme, and 4 perciforme fishes were infected by the nematod...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0472-4
更新日期：2007-07-01 00:00:00
abstract：ABTRACT:Structure of the helminth community of Megaleporinus obtusidens collected in Lake Guaíba was evaluated, and the results indicated that the diversity of helminth species was probably determined by fish behavior and eating habits. The influence of sex, weight, and standard length of hosts for parasitic indices wa...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5933-4
更新日期：2018-08-01 00:00:00
abstract：:Cystic echinococcosis (CE) is a widespread zoonosis. For treating single echinococcal cysts during the last decades, therapeutic puncture of the cyst, aspiration, injection of a scolicide, and re-aspiration (PAIR) has been established as a minimal-invasive alternative method to surgery. A recent review on the complica...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-4275-0
更新日期：2015-02-01 00:00:00
abstract：:Two of the three vector species of Schistosoma mansoni Sambon, 1907 in Brazil occur in the state of Maranhão: Biomphalaria glabrata (Say, 1818) and Biomphalaria straminea (Dunker, 1848). For the implementation of effective measures to combat schistosomiasis, it is necessary to identify the spatial and seasonal dynamic...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5810-1
更新日期：2018-05-01 00:00:00
abstract：:Over the past decade, advances in proteomic and mass spectrometry techniques and the sequencing of the Plasmodium falciparum genome have led to an increasing number of studies regarding the parasite proteome. However, these studies have focused principally on parasite protein expression, neglecting parasite-induced va...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2521-2
更新日期：2012-02-01 00:00:00
abstract：:Three actinosporean types--raabeia, aurantiactinomyxon, and guyenotia--from the oligochaete Branchiura sowerbyi Beddard collected from a crucian carp (Carassius auratus gibelio) pond are described in this report. Compared with the actinospores described previously, the raabeia type presents similar spore shape with th...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3306-6
更新日期：2013-04-01 00:00:00
abstract：:The purpose of the present study was to investigate the acaricidal and larvicidal activity against the larvae of Haemaphysalis bispinosa Neumann (Acarina: Ixodidae) and larvae of hematophagous fly Hippobosca maculata Leach (Diptera: Hippoboscidae) and against the fourth-instar larvae of malaria vector, Anopheles steph...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2473-6
更新日期：2012-08-01 00:00:00
abstract：:In 1997, an outbreak of alveolar echinococcosis in Japanese monkeys (Macaca fuscata) occurred in a zoo in Hokkaido, Japan. Twelve infected monkeys from a colony (n = 57) were diagnosed serologically by Western blotting, and ultrasonography showed the presence of tumor-like tissue in the livers of nine monkeys. The 12 ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1627-2
更新日期：2009-12-01 00:00:00
abstract：:Molecular characterization studies on Setaria equina are limited. The present study aimed to characterize S. equina at the cytochrome c oxidase gene and to examine its phylogenetic relationships with other filarid species. Sequence analysis showed 100% nucleotide homology with an S. equina sequence from Italy (AJ54487...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06917-8
更新日期：2020-12-01 00:00:00
abstract：:Trypanosoma cruzi causes Chagas' disease, a systemic infection that affects cells of meso-, endo-, and ectodermic origin. However, as far as we know, the presence of T. cruzi stages in bone has not been reported previously, and it has scarcely been investigated in cartilage. We inoculated 7- and 20-day-old (8 and 15 g...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0211-2
更新日期：2006-11-01 00:00:00
abstract：:Sticky traps were mounted on heifers and sheep to assess Culicoides spp. (Diptera: Ceratopogonidae) host preference. Initially, four coloured 200-cm(2) sticky traps (white, clear, yellow and blue) were attached to the backs of each of ten Friesian heifers that were released into open pasture for 24 h, repeated on six ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3974-x
更新日期：2014-08-01 00:00:00
abstract：:Severe and complicated malaria is usually caused by Plasmodium falciparum malaria (PF) but it has been increasingly observed that Plasmodium vivax malaria (PV), which was otherwise considered to be benign malaria, with a low case-fatality ratio, can also occasionally result in severe disease as with PF malaria. There ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2776-7
更新日期：2012-06-01 00:00:00
abstract：:Three monoclonal antibodies generated by immunization of mice with Plasmodium berghei-infected red blood cells were found to react with the 75-kDa heat-shock protein (HSP70) present in liver stages and erythrocytic forms of the parasites. These antibodies were shown to react with a recombinant protein encoding the car...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00932618
更新日期：1994-01-01 00:00:00
abstract：:Specimens of Bertiella studeri (Cyclophyllidea, Anoplocephalidae) that have been preserved in ethanol or fixed permanently in formalin for >2 years were used for DNA extraction and molecular characterization. DNA was amplified via PCR from samples collected from different monkey and human hosts using eucestoda-specifi...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2550-x
更新日期：2012-02-01 00:00:00
abstract：:Effectiveness of an oral combination of toltrazuril and iron dextran (Baycox(®) Iron) to maintain weaning weight by preventing coccidiosis caused by Isospora suis and iron-deficiency anaemia in neonatal piglets was investigated on three commercial pig farms with a history of coccidiosis: two in Mexico and one in Brazi...
journal_title：Parasitology research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00436-015-4525-9
更新日期：2015-08-01 00:00:00
abstract：:The ethanolic leaf extract of Cassia obtusifolia was investigated for their larvicidal and oviposition deterrence effects against Anopheles stephensi. Concentrations ranging from 25 to 125 mg/l were assessed at 24 h post-treatment against late third instar larvae. The leaf extract had significant larvicidal effect wit...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1197-8
更新日期：2009-01-01 00:00:00
abstract：:High levels of lactate dehydrogenase (LDH; EC 1. 1. 1. 27) activity have been detected in the filarial worm Molinema dessetae. The two major LDH isoenzymes (LDH1 and LDH2) from female worms were purified by successive chromatography on diethylaminoethyl (DEAE)-Sepharose, carboxymethyl (CM)-Sepharose, and hydroxyapatit...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050184
更新日期：1996-01-01 00:00:00
abstract：:Echinostoma trivolvis adults grown in golden hamsters were treated in vitro with [3H]-tyrosine to label sperm and transplanted to uninfected hamsters alone or with four to six unlabeled adults. After 4-5 days, worms were recovered, processed for autoradiography, and observed for silver grains over their seminal recept...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00932258
更新日期：1993-01-01 00:00:00
abstract：:In a survey study on the macroscopic species of Sarcocystis infecting domestic sheep (Ovis aries) and cattle (Bos taurus) in Egypt, the macrosarcocysts of Sarcocystis gigantea and Sarcocystis medusiformis were detected in the carcasses of 33 domestic sheep out of a total of 250 (13.20%), whereas Sarcocystis hirsuta ma...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-07002-w
更新日期：2021-01-18 00:00:00
abstract：:Blastocystis sp. is the most common eukaryotic parasite in the intestinal tract of humans. Due to its strong impact in public health, in this study, we determined the frequency of different Blastocystis subtypes in patients in France. We hypothesized on the mode of transmission and tested a possible relationship betwe...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1398-9
更新日期：2009-08-01 00:00:00
abstract：:The structure modulation of follicular cells and the ovarian changes during fourth larval instar and pupal stage of the malaria vector mosquitoes Anopheles pharoensis Theobald were investigated using the light and electron microscopy. The generative organs consist of a pair of polytrophic ovaries (OV), which are oblon...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-4099-y
更新日期：2014-11-01 00:00:00
abstract：:The principal health problem in small ruminants is helminthiasis and the rapid development of nematode resistance to anthelminthics has limited the success of control in several countries, stimulating the search for alternatives. In this study, extracts of immature fruits of the mango Mangifera indica L. var Ubá were ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3017-4
更新日期：2012-12-01 00:00:00
abstract：:Strongyloides stercoralis can cause severe infection both in humans and dogs. Coproparasitological examination has low sensitivity for the diagnosis of this parasite; hence, different diagnostic techniques have been implemented. However, serology and molecular methods have been assessed almost exclusively in humans. I...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5468-0
更新日期：2017-07-01 00:00:00
abstract：:Using molecular techniques, we documented the presence of Nosema ceranae in honeybees (Apis mellífera) from Argentina. Samples were collected from A. mellifera colonies in 38 districts of Buenos Aires province, Argentina. Molecular characterization was achieved with a multiplex PCR-based method, which allows parallel ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2566-2
更新日期：2012-02-01 00:00:00
abstract：:In Egypt, reclaiming portions of the desert using water from the Nile has resulted in large-scale invasion of Biomphalaria alexandrina in these regions. Studies exploring the local adaptation of Schistosoma mansoni to its snail host have been carried out to predict the extension of schistosomiasis to newly reclaimed a...
journal_title：Parasitology research
pub_type： 杂志文章,meta分析
doi：10.1007/s00436-014-3756-5
更新日期：2014-03-01 00:00:00
abstract：:Helminths are one of the major health problems of working donkeys, often with heavy worm burden and contributing to their early demise and/or reduction in their work output. Cross-sectional and longitudinal studies were conducted to investigate the current infection prevalence and level of strongyles infection donkeys...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5485-z
更新日期：2017-07-01 00:00:00
abstract：:The complete coding sequence of manganese superoxide dismutase (Mn-SOD) of Trichinella pseudospiralis (Tp) was obtained and characterized for the first time by degenerative reverse transcription polymerase chain reaction (RT-PCR) and rapid amplification of complementary DNA ends (RACE) reactions. The open reading fram...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0755-9
更新日期：2008-01-01 00:00:00
abstract：:From March to October 2003, a total of 2,518 host-seeking Ixodes ricinus ticks (1,944 nymphs, 264 females, 310 males) were collected by blanket dragging at 45 sites all over the city area of Bonn, western Germany, to be checked for Borrelia burgdorferi infection. The collection sites included 20 private gardens, nine ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-004-1240-3
更新日期：2005-01-01 00:00:00
abstract：:This is the first report of cryptosporidiosis in a bactrian camel (Camelus bactrianus) in China. Two Cryptosporidium isolates derived from the same bactrian camel (3-year-old) in November 2005 and April 2006 were characterized using sequence and phylogenetic analysis of the small-subunit rRNA (18S rRNA), 70-kDa heat s...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0851-x
更新日期：2008-04-01 00:00:00
abstract：:Intraspecific variation in Schistosoma mansoni infection and modulation of its expression by vertebrate host genetics was studied by evaluation of some biological parameters of the infection in BALB/c and C57BL/6 mice infected with one Brazilian (BH) and two Venezuelan (YT and SM) laboratory strains of the parasite. M...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/pl00008565
更新日期：2001-02-01 00:00:00
