Fatty acid desaturation: variations on an oxidative theme.

Abstract:

:Significant progress in our understanding of the mechanism of fatty acid desaturation has been achieved. The site of initial oxidation has been determined for several membrane-bound desaturases and a common cryptoregiochemical theme has been revealed. The results of several studies, including a detailed analysis of a soluble plant desaturase system, point to a close mechanistic relationship between dehydrogenation and hydroxylation pathways.

journal_name

Curr Opin Chem Biol

authors

Behrouzian B,Buist PH

doi

10.1016/s1367-5931(02)00365-4

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

577-82

issue

5

eissn

1367-5931

issn

1879-0402

pii

S1367593102003654

journal_volume

6

pub_type

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