Abstract:
:Time-related aspects of health have attracted increasing interest, and it has become evident that many medical situations concern the exchange of present-day costs for future benefits. Traditional decision analytic paradigms weigh the probability of outcomes and the value of outcomes. Such analyses are incomplete if they do not consider the time of the outcome as well. The concept of diminishing value over time is positive discounting. Time discounting processes and effects have a potentially large impact on clinical decision making. Therefore, characteristics of discounting should be taken into consideration. Discounting processes are variable with individuals and also within different contexts such as gains and losses. No single model can be expected to describe time-related decisions within health. A more diversified use and critical appraisal of these concepts in medicine become more important as we attempt to refine decision models. A summary of valuation factors in medical decision making is presented: (a) long-term decisions are very sensitive to discount rates; (b) discount rates are greater for gains than for losses; (c) discount rates vary by domain, by outcome, by individuals over time, and by level of certainty; (d) individual preferences may reverse themselves over time; (e) the doctor uses expected value; the patient is risk aversive; (f) over a lifetime perspective, a flat or even negative discount rate will result in choices that minimize lifetime disability.
journal_name
J Clin Epidemioljournal_title
Journal of clinical epidemiologyauthors
Ortendahl M,Fries JFdoi
10.1016/s0895-4356(02)00447-xsubject
Has Abstractpub_date
2002-09-01 00:00:00pages
843-8issue
9eissn
0895-4356issn
1878-5921pii
S089543560200447Xjournal_volume
55pub_type
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/0895-4356(95)00019-z
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章,meta分析
doi:10.1016/s0895-4356(99)00213-9
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To address methodologic issues in searching for observational studies by presenting database search methods and results. STUDY DESIGN AND SETTING:Results of two literature searches for publications reporting on observational studies of alcohol consumption and the risk of breast cancer and large bowel cancer ...
journal_title:Journal of clinical epidemiology
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doi:10.1016/j.jclinepi.2005.03.004
更新日期:2005-09-01 00:00:00
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journal_title:Journal of clinical epidemiology
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doi:10.1016/0895-4356(95)00012-s
更新日期:1995-09-01 00:00:00
abstract::The relationships between the prevalence of hepatitis B surface antigen (HBsAg), mean annual per capita alcohol consumption and primary liver cancer (PLC) death rates were explored in 30 countries. HBsAg prevalence was associated, significantly, with the logarithm of the primary liver cancer death rate (simple correla...
journal_title:Journal of clinical epidemiology
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doi:10.1016/0895-4356(88)90165-5
更新日期:1988-01-01 00:00:00
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journal_title:Journal of clinical epidemiology
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doi:10.1016/j.jclinepi.2008.09.008
更新日期:2009-07-01 00:00:00
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journal_title:Journal of clinical epidemiology
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更新日期:2010-08-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/s0895-4356(03)00119-7
更新日期:2003-07-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/s0895-4356(97)00021-8
更新日期:1997-06-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.jclinepi.2016.02.023
更新日期:2016-08-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/s0895-4356(98)00094-8
更新日期:1998-11-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/j.jclinepi.2010.09.009
更新日期:2011-03-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/j.jclinepi.2007.11.016
更新日期:2008-10-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/0895-4356(88)90080-7
更新日期:1988-01-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jclinepi.2007.08.012
更新日期:2008-07-01 00:00:00
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doi:10.1016/0895-4356(94)90085-x
更新日期:1994-12-01 00:00:00
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journal_title:Journal of clinical epidemiology
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doi:10.1016/s0895-4356(00)00373-5
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journal_title:Journal of clinical epidemiology
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更新日期:2017-01-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.jclinepi.2014.06.008
更新日期:2014-10-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/j.jclinepi.2011.12.013
更新日期:2012-07-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.jclinepi.2018.12.015
更新日期:2019-05-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/s0895-4356(99)00021-9
更新日期:1999-06-01 00:00:00
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/j.jclinepi.2017.11.004
更新日期:2018-02-01 00:00:00
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journal_title:Journal of clinical epidemiology
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doi:10.1016/0895-4356(94)90129-5
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journal_title:Journal of clinical epidemiology
pub_type: 杂志文章,评审
doi:10.1016/s0895-4356(01)00447-4
更新日期:2001-12-01 00:00:00
abstract::Pragmatic trials aim to inform clinical decision making by measuring the effect of a treatment in clinical practice. The purpose of the PRECIS-2 tool is to support in designing a truly pragmatic trial. We comment on a study by Forbes et al., who assessed the applicability of the PRECIS-2 tool. The tool will prove part...
journal_title:Journal of clinical epidemiology
pub_type: 杂志文章
doi:10.1016/j.jclinepi.2017.06.006
更新日期:2017-10-01 00:00:00