Abstract:
:Aging produces a loss in a number of behavioral and cognitive functions, including sleep. Hypocaloric diet is one of the few methods that have been shown to retard the effects due to age. However, the effects of such a diet on sleep have never been investigated. In the present study, 21 months old male F344 rats fed a 60% calorie-reduced diet continued to have a significant reduction in delta power (0.3-4 Hz EEG), less sleep following 12 h total sleep deprivation (TSD) and increased sensitivity to caffeine compared to young rats (3 months) fed a similar diet. These results indicate that caloric restriction is unable to prevent the decline in sleep that occurs with aging.
journal_name
Neurobiol Agingjournal_title
Neurobiology of agingauthors
Salin-Pascual RJ,Upadhyay U,Shiromani PJdoi
10.1016/s0197-4580(02)00030-1subject
Has Abstractpub_date
2002-09-01 00:00:00pages
771-6issue
5eissn
0197-4580issn
1558-1497pii
S0197458002000301journal_volume
23pub_type
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