Lateral position decreases collapsibility of the passive pharynx in patients with obstructive sleep apnea.

Abstract:

BACKGROUND:Reduction of nocturnal obstructive events during lateral position in patients with obstructive sleep apnea was previously reported. However, little information is available regarding mechanisms of the improvement and the precise pharyngeal site influenced by the lateral position. The authors tested the hypothesis that structural properties of the passive pharynx change by changing the body position from supine to lateral. METHOD:Total muscle paralysis was induced with general anesthesia in eight patients with obstructive sleep apnea, eliminating neuromuscular factors contributing to pharyngeal patency. The cross-sectional area of the pharynx was measured endoscopically at different static airway pressures. Comparison of static pressure-area plot between the positions allowed assessment of the influence of the position change on the mechanical properties of the pharynx. RESULTS:The static pressure-area curves of the lateral position were above those of the supine position, with increasing maximum cross-sectional area and decreasing the closing pressure at both retropalatal and retroglossal airways. CONCLUSIONS:Lateral position structurally improves maintenance of the passive pharyngeal airway in patients with obstructive sleep apnea.

journal_name

Anesthesiology

journal_title

Anesthesiology

authors

Isono S,Tanaka A,Nishino T

doi

10.1097/00000542-200210000-00006

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

780-5

issue

4

eissn

0003-3022

issn

1528-1175

pii

00000542-200210000-00006

journal_volume

97

pub_type

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