当前位置： SCI文献检索 > JOURNAL OF NEUROSCIENCE METHODS期刊下所有文献 > Improved ceramic-based multisite microelectrode for rapid measurements of L-glutamate in the CNS.

Improved ceramic-based multisite microelectrode for rapid measurements of L-glutamate in the CNS.

Abstract：

:This paper describes improvements and further characterization of a ceramic-based multisite microelectrode for in vivo measurements of L-glutamate. Improvements include increased recording area, insulation deposition using photolithography for more uniform recording sites and forming the microelectrodes using a diamond saw providing smoother microelectrode edges. The new microelectrodes are triangular in shape, 1 cm in length and taper from 1 mm to a 2-5 microm tip. Details on performing in vivo measurements are given, including microelectrode preparation, pitfalls of the recording method and approaches to enhance reproducibility of the technique. The detection limit for L-glutamate was lowered to approximately 0.5 microM and a self-referencing recording technique was utilized to remove interferents as well as decrease noise. Applications of the microelectrodes to study L-glutamate uptake and release in rat prefrontal cortex, cortex, cerebellum and striatum are included.

journal_name

J Neurosci Methods

journal_title

Journal of neuroscience methods

authors

Burmeister JJ,Pomerleau F,Palmer M,Day BK,Huettl P,Gerhardt GA

doi

10.1016/s0165-0270(02)00172-3

subject

Has Abstract

pub_date

2002-09-30 00:00:00

pages

163-71

issue

2

eissn

0165-0270

issn

1872-678X

pii

S0165027002001723

journal_volume

119

pub_type

杂志文章

相关文献

JOURNAL OF NEUROSCIENCE METHODS文献大全
  • A flow rate monitor for a variety of physiological preparations, including in vitro brain slices.

    abstract：:A flow rate monitor system for constant perfusion of media for maintaining physiological preparations, particularly in vitro brain slices, is described. The system consists of 3 components: the counter with a drip rate meter and alarm; a drop sensor; and a remote DC power supply. It provides accurate and immediate rea...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/0165-0270(88)90024-6

    authors： Rinaldi PC,Brown AM

    更新日期：1988-02-01 00:00:00

  • MR connectomics: Principles and challenges.

    abstract：:MR connectomics is an emerging framework in neuro-science that combines diffusion MRI and whole brain tractography methodologies with the analytical tools of network science. In the present work we review the current methods enabling structural connectivity mapping with MRI and show how such data can be used to infer ...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章,评审

    doi：10.1016/j.jneumeth.2010.01.014

    authors： Hagmann P,Cammoun L,Gigandet X,Gerhard S,Grant PE,Wedeen V,Meuli R,Thiran JP,Honey CJ,Sporns O

    更新日期：2010-12-15 00:00:00

  • Wireless transmission of fast-scan cyclic voltammetry at a carbon-fiber microelectrode: proof of principle.

    abstract：:Fast-scan cyclic voltammetry (FSCV) at a carbon-fiber microelectrode (CFM) provides exquisite temporal and spatial resolution for monitoring brain chemistry. The utility of this approach has recently been demonstrated by measuring sub-second dopamine changes associated with behavior. However, one drawback is the cable...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2004.04.043

    authors： Garris PA,Ensman R,Poehlman J,Alexander A,Langley PE,Sandberg SG,Greco PG,Wightman RM,Rebec GV

    更新日期：2004-12-30 00:00:00

  • Recovering Wood and McCarthy's ERP-prototypes by means of ERP-specific procrustes-rotation.

    abstract：BACKGROUND:The misallocation of treatment-variance on the wrong component has been discussed in the context of temporal principal component analysis of event-related potentials. There is, until now, no rotation-method that can perfectly recover Wood and McCarthy's prototypes without making use of additional information...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2017.11.011

    authors： Beauducel A

    更新日期：2018-02-01 00:00:00

  • Design of a fused phantom for quantitative evaluation of brain metabolites and enhanced quality assurance testing for magnetic resonance imaging and spectroscopy.

    abstract：BACKGROUND:Magnetic resonance imaging and spectroscopy (MRI-MRS) is a useful tool for the identification and evaluation of chemical changes in anatomical regions. Quality assurance (QA) is performed in either images or spectra using QA phantom. Therefore, consistent and uniform technical MRI-MRS QA is crucial. NEW MET...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2015.08.005

    authors： Song KH,Kim SY,Lee DW,Jung JY,Lee JH,Baek HM,Choe BY

    更新日期：2015-11-30 00:00:00

  • Frequency-based approach to the study of semantic brain networks connectivity.

    abstract：:The interactions among cerebral regions involved in semantic word generations are explored through connectivity analysis based on fMRI data through multivariate autoregressive model (MVAR). Connections among the pars triangularis of the left inferior frontal gyrus (L45), the lateral fusiform girus (LFG) and the left m...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2012.10.005

    authors： Bianchi AM,Marchetta E,Tana MG,Tettamanti M,Rizzo G

    更新日期：2013-01-30 00:00:00

  • A mobile, high-throughput semi-automated system for testing cognition in large non-primate animal models of Huntington disease.

    abstract：BACKGROUND:For reasons of cost and ethical concerns, models of neurodegenerative disorders such as Huntington disease (HD) are currently being developed in farm animals, as an alternative to non-human primates. Developing reliable methods of testing cognitive function is essential to determining the usefulness of such ...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2015.08.025

    authors： McBride SD,Perentos N,Morton AJ

    更新日期：2016-05-30 00:00:00

  • Noninvasive method of immortalized neural stem-like cell transplantation in an experimental model of Huntington's disease.

    abstract：:A loss of neostriatal neurons is a characteristic of Huntington's disease (HD), and neural tissue transplantation has been performed directly into the striatum. Since the neural stem cells have ability to migrate into the lesion site, we administered immortalized neural stem-like cells (NSC) into the ventricle or via ...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2005.09.013

    authors： Lee ST,Park JE,Lee K,Kang L,Chu K,Kim SU,Kim M,Roh JK

    更新日期：2006-04-15 00:00:00

  • Chromatin immunoprecipitation and gene expression analysis of neuronal subtypes after fluorescence activated cell sorting.

    abstract：BACKGROUND:With advances in cell capture, gene expression can now be studied in neuronal subtypes and single cells; however, studying epigenetic mechanisms that underlie these changes presents challenges. Moreover, chromatin immunoprecipitation (ChIP) protocols optimized for low cell number do not adequately address te...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2016.02.006

    authors： Finegersh A,Homanics GE

    更新日期：2016-04-01 00:00:00

  • The extraction of motion-onset VEP BCI features based on deep learning and compressed sensing.

    abstract：BACKGROUND:Motion-onset visual evoked potentials (mVEP) can provide a softer stimulus with reduced fatigue, and it has potential applications for brain computer interface(BCI)systems. However, the mVEP waveform is seriously masked in the strong background EEG activities, and an effective approach is needed to extract t...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2016.11.002

    authors： Ma T,Li H,Yang H,Lv X,Li P,Liu T,Yao D,Xu P

    更新日期：2017-01-01 00:00:00

  • Odor-induced emotion recognition based on average frequency band division of EEG signals.

    abstract：BACKGROUND:Emotion recognition plays a key role in multimedia. To enhance the sensation of reality, smell has been incorporated into multimedia systems because it can directly stimulate memories and trigger strong emotions. NEW METHOD:For the recognition of olfactory-induced emotions, this study explored a combination...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2020.108599

    authors： Hou HR,Zhang XN,Meng QH

    更新日期：2020-01-21 00:00:00

  • Relation between myelin area and axon diameter in the aortic depressor nerve of spontaneously hypertensive rats.

    abstract：:The hypothesis that the aortic depressor nerve (ADN) from spontaneously hypertensive rats (SHR) does not show the expected correlation between myelin sheath area and the axonal diameter of myelinated fibers detected in normotensive rat myelinated fibers was tested by means of regression analysis. Proximal and distal s...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2005.04.007

    authors： Fazan VP,Salgado HC,dos Reis GC,Barreira AA

    更新日期：2005-10-30 00:00:00

  • Data-driven approach to the estimation of connectivity and time delays in the coupling of interacting neuronal subsystems.

    abstract：:One of the challenges in neuroscience is the detection of directionality between signals reflecting neural activity. To reveal the directionality of coupling and time delays between interacting multi-scale signals, we use a combination of a data-driven technique called empirical mode decomposition (EMD) and partial di...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2010.06.004

    authors： Silchenko AN,Adamchic I,Pawelczyk N,Hauptmann C,Maarouf M,Sturm V,Tass PA

    更新日期：2010-08-15 00:00:00

  • Comparing connectivity metrics in cortico-cortical evoked potentials using synthetic cortical response patterns.

    abstract：BACKGROUND:Cortico-Cortical Evoked Potentials (CCEPs) are a novel low frequency stimulation method used for brain mapping during intracranial epilepsy investigations. Only a handful of metrics have been applied to CCEP data to infer connectivity, and no comparison as to which is best has been performed. NEW METHOD:We ...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2019.108559

    authors： Prime D,Woolfe M,Rowlands D,O'Keefe S,Dionisio S

    更新日期：2020-01-09 00:00:00

  • A simple method for fabricating horizontal and vertical microwire arrays.

    abstract：:Microwire array electrodes are important in multi-site, multiple single-unit recording experiments. A simple method is described herein for the construction of microwire arrays consisting of evenly spaced insulated microwires in either horizontal or vertical orientations. Several key steps in the fabrication of a good...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/s0165-0270(03)00235-8

    authors： Tsai ML,Yen CT

    更新日期：2003-12-30 00:00:00

  • A portable chamber for long-distance transport of surviving human brain slice preparations.

    abstract：:Incubation chambers for surviving brain slice preparations are in most cases designed to be stationary. For investigations on human brain tissue resected for the treatment of brain tumor or epilepsy, portable incubation chambers are needed in addition to stationary ones to allow transport of the slices between laborat...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/0165-0270(96)00072-6

    authors： Köhling R,Lücke A,Straub H,Speckmann EJ

    更新日期：1996-08-01 00:00:00

  • Time-frequency analysis of resting state and evoked EEG data recorded at higher magnetic fields up to 9.4 T.

    abstract：BACKGROUND:Combining both high temporal and spatial resolution by means of simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) is of relevance to neuroscientists. This combination, however, leads to a distortion of the EEG signal by the so-called cardio-ballistic artefacts. The ai...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2015.07.011

    authors： Abbasi O,Dammers J,Arrubla J,Warbrick T,Butz M,Neuner I,Shah NJ

    更新日期：2015-11-30 00:00:00

  • A combined recording and microiontophoresis technique for input-output analysis of single neurons in the mammalian CNS.

    abstract：:A method is described for producing electrolytically sharpened and lacquer-insulated steel microelectrodes and for their attachment to a multibarrel micropipet assembly by light-curing bonding compound. This electrode complex is specially designed for recordings from deep brain structures. It permits the analysis of t...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/0165-0270(88)90007-6

    authors： Gottschaldt KM,Hicks TP,Vahle-Hinz C

    更新日期：1988-04-01 00:00:00

  • Physiological monitoring of small animals during magnetic resonance imaging.

    abstract：:Maintaining a stable physiologic state is essential when studying animal models of epilepsy with simultaneous electroencephalograph (EEG) and functional magnetic resonance imaging (fMRI) or EEG and magnetic resonance spectroscopy (MRS). To achieve and maintain such stability in rats in the MRI environment, a minimally...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2004.11.019

    authors： Mirsattari SM,Bihari F,Leung LS,Menon RS,Wang Z,Ives JR,Bartha R

    更新日期：2005-06-15 00:00:00

  • An accurate method for the quantification of cytochrome C oxidase in tissue sections.

    abstract：:Cytochrome oxidase (COX) is the enzyme that constitutes the last step of the mitochondrial electron transport chain for the production of ATP. Measurement of COX activity can be achieved by histochemistry, thus providing information about the metabolic status of the brain. Brain regions with high metabolism will prese...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2013.01.010

    authors： Melendez-Ferro M,Rice MW,Roberts RC,Perez-Costas E

    更新日期：2013-04-15 00:00:00

  • Simultaneous quantification of seven hippocampal neurotransmitters in depression mice by LC-MS/MS.

    abstract：BACKGROUND:There is no method available to simultaneously detect GABA, Glu, Epi, NE, DA, 5-HT and 5-HIAA in mouse hippocampus. NEW METHOD:A rapid and sensitive LC-MS/MS method has been developed for simultaneously measuring seven neurotransmitters in mouse hippocampus. The analytes were detected in positive mode with ...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2014.04.004

    authors： Huang F,Li J,Shi HL,Wang TT,Muhtar W,Du M,Zhang BB,Wu H,Yang L,Hu ZB,Wu XJ

    更新日期：2014-05-30 00:00:00

  • High-performance liquid chromatography/tandem mass spectrometric assay for the simultaneous measurement of dopamine, norepinephrine, 5-hydroxytryptamine and cocaine in biological samples.

    abstract：:A rapid liquid chromatography/tandem mass spectrometry (LC-MS/MS) method has been developed for the measurement of dopamine (DA), 5-hydroxytryptamine (5HT) and norepinephrine (NE) in brain microdialysates. The assay has also been utilised for the simultaneous measurement of these neurotransmitters and cocaine in brain...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2004.03.021

    authors： Hows ME,Lacroix L,Heidbreder C,Organ AJ,Shah AJ

    更新日期：2004-09-30 00:00:00

  • Automated quantification of synapses by fluorescence microscopy.

    abstract：:The quantification of synapses in neuronal cultures is essential in studies of the molecular mechanisms underlying synaptogenesis and synaptic plasticity. Conventional counting of synapses based on morphological or immunocytochemical criteria is extremely work-intensive. We developed a fully automated method which qua...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2011.11.010

    authors： Schätzle P,Wuttke R,Ziegler U,Sonderegger P

    更新日期：2012-02-15 00:00:00

  • Application of the unilateral 6-hydroxydopamine rat model of rotational behavior to the study of conditioned drug effects.

    abstract：:In rats with unilateral 6-hydroxydopamine lesions of the substantia nigra apomorphine reliably induces a response of contralateral rotation. The present study shows that this response can readily be conditioned to a test environment which the rats are briefly exposed to during the onset of the apomorphine-induced rota...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/0165-0270(88)90046-5

    authors： Carey RJ

    更新日期：1988-01-01 00:00:00

  • Variation of the choline signal intensity in the dorsolateral prefrontal cortex of rats exposed to the forced swimming test as detected by in vivo 1H MR spectroscopy.

    abstract：BACKGROUND:(1)H magnetic resonance spectroscopy (MRS) has documented an increased Cho/Cr ratio in the dorsolateral prefrontal cortex (DLPFC) in major depressive disorder (MDD). The aim of this study was to investigate neurochemical alterations in the left DLPFC, considered a main area of pathogenesis in depression, usi...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2007.05.022

    authors： Hong ST,Choi CB,Park C,Hong KS,Cheong C,Jeon YW,Choe BY

    更新日期：2007-09-15 00:00:00

  • A simplified method for the measurement of caffeine in plasma and brain: evidence for a cortical-subcortical caffeine concentration differential in brain.

    abstract：:We describe a much simplified high-performance liquid chromatography (HPLC) method for the measurement of caffeine in plasma and brain. A particularly attractive feature of this method is that a simple methanol/water (60:40) mobile phase can be used both for plasma and brain samples. In addition, the method is compati...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/0165-0270(94)90139-2

    authors： Carey RJ,DePalma G

    更新日期：1994-07-01 00:00:00

  • MNE Scan: Software for real-time processing of electrophysiological data.

    abstract：BACKGROUND:Magnetoencephalography (MEG) and Electroencephalography (EEG) are noninvasive techniques to study the electrophysiological activity of the human brain. Thus, they are well suited for real-time monitoring and analysis of neuronal activity. Real-time MEG/EEG data processing allows adjustment of the stimuli to ...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2018.03.020

    authors： Esch L,Sun L,Klüber V,Lew S,Baumgarten D,Grant PE,Okada Y,Haueisen J,Hämäläinen MS,Dinh C

    更新日期：2018-06-01 00:00:00

  • A novel mouse model of contralateral C7 transfer via the pretracheal route: A feasibility study.

    abstract：BACKGROUND:Contralateral seventh cervical nerve transfer (contralateral C7 transfer) is a novel treatment for patients with spastic paralysis, including stroke and traumatic brain injury. However, little is known on changes in plasticity that occur in the intact hemisphere after C7 transfer. An appropriate surgical mod...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2019.108445

    authors： Ye X,Shen YD,Feng JT,Wang F,Gao ZR,Lei GW,Yu AP,Wang CP,Liang CM,Xu WD

    更新日期：2019-12-01 00:00:00

  • In vitro isolation of neural precursor cells from the adult pig subventricular zone.

    abstract：:In order to improve cell therapy techniques, we have characterized a multipotent neural precursor cell isolation technique from the subventricular zone of adult pig brain. The pig is a non-primate species that is immunologically closest to human. The proliferative zone of this neurogenic structure was first localized ...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2009.06.008

    authors： Liard O,Segura S,Pascual A,Gaudreau P,Fusai T,Moyse E

    更新日期：2009-09-15 00:00:00

  • High throughput quantification of mutant huntingtin aggregates.

    abstract：:Mutant protein aggregates are an important biomarker in Huntington's and other neurodegenerative diseases however their quantification has typically relied on manual imaging and counting, or cell-free assays, which do not allow for concurrent analysis of cell viability. Here we describe four automated high throughput ...

    journal_title：Journal of neuroscience methods

    pub_type： 杂志文章

    doi：10.1016/j.jneumeth.2008.02.007

    authors： Scotter EL,Narayan P,Glass M,Dragunow M

    更新日期：2008-06-15 00:00:00