Role of Orbscan II in screening keratoconus suspects before refractive corneal surgery.

Abstract:

OBJECTIVE:To evaluate the relationship between videokeratographic keratoconus screening programs and Orbscan II topography. DESIGN:Prospective, observational case series and instrument validation study. PARTICIPANTS:Sixty consecutive eyes with suspicious videokeratography (TMS-1, Tomey Technology, Waltham, MA) were evaluated before undergoing laser in situ keratomileusis (LASIK) surgery. A control group of 50 consecutive eyes without suspicious features by videokeratography was also evaluated. METHODS:Keratoconus screening programs, using the Rabinowitz and Klyce/Maeda methods and Orbscan II (Bausch & Lomb, Claremont, CA) topographies were performed on these patients. MAIN OUTCOME MEASURES:Specific parameters evaluated on the Orbscan II topographies were anterior elevation, posterior elevation, and thinnest pachymetry. RESULTS:Compared with a control group of patients without suspicious videokeratography, there was a statistically significant difference in the mean posterior elevation and mean anterior elevation in the groups with positive keratoconus testing with the Rabinowitz or Klyce/Maeda methods. For patients who met both the Rabinowitz and Klyce/Maeda criteria for keratoconus, the mean posterior elevation was 44 +/- 2.5 micro m compared with a posterior elevation of 21 +/- 0.6 micro m for the control group. There was no statistically significant difference in the mean thinnest pachymetry between the control group and all keratoconus suspect groups. CONCLUSIONS:Patients with positive keratoconus screening tests have higher anterior and posterior elevation on Orbscan II topography. When used in combination with videokeratography, the Orbscan II topography system may be helpful in identifying patients who are potentially at high risk for developing ectasia after LASIK.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Rao SN,Raviv T,Majmudar PA,Epstein RJ

doi

10.1016/s0161-6420(02)01121-1

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

1642-6

issue

9

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(02)01121-1

journal_volume

109

pub_type

杂志文章
  • Initial 5-fluorouracil trabeculectomy in uncomplicated glaucoma.

    abstract::The effectiveness of trabeculectomy with adjunctive low-dose 5-fluorouracil (5-FU) as the initial surgical procedure in uncomplicated glaucoma was evaluated retrospectively in a consecutive series of 52 patients (mean follow-up, 18.6 +/- 11.7 mos) and 74 control subjects. The cumulative 2-year success (intraocular pre...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(91)32180-8

    authors: Liebmann JM,Ritch R,Marmor M,Nunez J,Wolner B

    更新日期:1991-07-01 00:00:00

  • Enucleation versus plaque irradiation for choroidal melanoma.

    abstract::The Collaborative Ocular Melanoma Study (COMS) is an international, multicenter-controlled study. The organization includes an Executive Committee, Steering Committee, 6 Central Units, 32 Clinical Centers, and a Data and Safety Monitoring Committee. Scientifically, the COMS consists of (1) a randomized trial of patien...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(88)33086-1

    authors: Straatsma BR,Fine SL,Earle JD,Hawkins BS,Diener-West M,McLaughlin JA

    更新日期:1988-07-01 00:00:00

  • Analysis of a novel protocol of pulsed intravenous cyclophosphamide for recalcitrant or severe ocular inflammatory disease.

    abstract:PURPOSE:To analyze the success rate of pulsed intravenous (IV) cyclophosphamide (CyP) for noninfectious ocular inflammatory disease and to identify risk factors for failure of therapy. DESIGN:Retrospective, interventional, noncomparative cohort study. PARTICIPANTS:One hundred ten eyes of 65 patients. METHODS:Through...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2013.01.031

    authors: Suelves AM,Arcinue CA,González-Martín JM,Kruh JN,Foster CS

    更新日期:2013-06-01 00:00:00

  • Diurnal variation in corneal endothelial morphology.

    abstract::Transient changes in the corneal endothelium were the earliest detectable response to low atmospheric oxygen in experimental animals. Similar changes have been reported after hard and soft contact lens wear. We describe widespread transient cell changes by wide-field specular microscopy in the normal corneal endotheli...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34169-0

    authors: Khodadoust AA,Hirst LW

    更新日期:1984-10-01 00:00:00

  • Enhanced attachment of acanthamoeba to extended-wear silicone hydrogel contact lenses: a new risk factor for infection?

    abstract:PURPOSE:To establish if silicone hydrogel (S-H) contact lenses could be a risk factor for Acanthamoeba infection by facilitating the attachment of trophozoites to their surface and transfer to the cornea and to determine the effect Acanthamoeba culture technique, patient wear, and Pseudomonas biofilm coating have on at...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(02)01971-1

    authors: Beattie TK,Tomlinson A,McFadyen AK,Seal DV,Grimason AM

    更新日期:2003-04-01 00:00:00

  • Oculopalatal myoclonus after the one-and-a-half syndrome with facial nerve palsy.

    abstract:PURPOSE:The one-and-a-half syndrome is an eye movement disorder characterized by a unilateral gaze palsy and an ipsilateral internuclear ophthalmoplegia. The authors describe a previously unrecognized association between the one-and-a-half syndrome and oculopalatal myoclonus (OPM). METHODS:Five clinical cases are pres...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(96)30743-4

    authors: Wolin MJ,Trent RG,Lavin PJ,Cornblath WT

    更新日期:1996-01-01 00:00:00

  • Treatment of recurrent squamous papillomata of the conjunctiva by carbon dioxide laser vaporization.

    abstract::Complete resection of recurrent conjunctival squamous papillomata frequently may be exceedingly difficult, since such lesions are typically friable and multilobulated. Recurrent lesions often fill the fornicies and spill onto the lid margins. Moreover, since the human papillomavirus (HPV) has been linked to some of th...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(86)33634-0

    authors: Bosniak SL,Novick NL,Sachs ME

    更新日期:1986-08-01 00:00:00

  • Three major loci involved in age-related macular degeneration are also associated with polypoidal choroidal vasculopathy.

    abstract:PURPOSE:To investigate the frequency of variants in 3 major age-related macular degeneration (AMD)-associated loci in patients of European-American descent with polypoidal choroidal vasculopathy (PCV). DESIGN:Cross-sectional, case-control association study. PARTICIPANTS:Fifty-five patients with PCV, 368 patients with...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ophtha.2009.12.018

    authors: Lima LH,Schubert C,Ferrara DC,Merriam JE,Imamura Y,Freund KB,Spaide RF,Yannuzzi LA,Allikmets R

    更新日期:2010-08-01 00:00:00

  • 5-fluorouracil in combined trabeculectomy and clear-cornea phacoemulsification with posterior chamber intraocular lens implantation. A one-year randomized, controlled clinical trial.

    abstract:PURPOSE:To test the effect of postoperative subconjunctival 5-fluorouracil (5-FU) on the pressure outcome in combined procedure (limbus-based trabeculectomy + clear-cornea phacoemulsification). METHODS:Prospective randomized, controlled clinical trial; n = 24 eyes (24 patients) with concurrent open-angle glaucoma and ...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(97)30336-4

    authors: Gandolfi SA,Vecchi M

    更新日期:1997-02-01 00:00:00

  • Blebitis, early endophthalmitis, and late endophthalmitis after glaucoma-filtering surgery.

    abstract:PURPOSE:The differentiating characteristics in blebitis and early and late endophthalmitis after glaucoma filtration surgery are reviewed. METHODS:All admission records and operative reports, as well as available office notes, on patients with blebitis or bleb-associated endophthalmitis admitted to a large referral ey...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(97)30196-1

    authors: Ciulla TA,Beck AD,Topping TM,Baker AS

    更新日期:1997-06-01 00:00:00

  • Linear array multiple transducer ultrasonic examination of the eye.

    abstract::Dynamic ultrasonic imaging adds a time dimension to the clinical diagnosis of ocular pathology. A recent development in this area of ophthalmic sonography has been the introduction of an electronically scanned, multiple transducer system that provides improved real-time imaging of ocular tissue motion. This paper disc...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(83)34564-4

    authors: Susal AL,Gaynon MW,Walker JT

    更新日期:1983-03-01 00:00:00

  • Initial experience using the transconjunctival sutureless vitrectomy system for vitreoretinal surgery.

    abstract:OBJECTIVE:To describe the initial experience and to evaluate the safety and feasibility of using the 25-gauge Transconjunctival Sutureless Vitrectomy System (TSV) for a variety of vitreoretinal procedures. DESIGN:Retrospective review of a consecutive interventional case series. PARTICIPANTS:Thirty-five eyes of 33 pat...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(02)01119-3

    authors: Fujii GY,De Juan E Jr,Humayun MS,Chang TS,Pieramici DJ,Barnes A,Kent D

    更新日期:2002-10-01 00:00:00

  • Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2% and timolol 0.5% given twice daily in patients with glaucoma or ocular hypertension. Brimonidine Study Group 2.

    abstract:OBJECTIVE:To compare the long-term safety and ocular-hypotensive efficacy of brimonidine tartrate 0.2% with timolol maleate 0.5% administered twice daily in patients with glaucoma or ocular hypertension. DESIGN:A double-masked, parallel-group, active-controlled, multicenter clinical trial of 12 months' duration. PART...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0161-6420(98)91048-x

    authors: LeBlanc RP

    更新日期:1998-10-01 00:00:00

  • Risk factors for conversion to neovascular age-related macular degeneration based on longitudinal morphologic and visual acuity data.

    abstract:PURPOSE:To use longitudinal quantitative morphologic and visual acuity (VA) data to investigate the risk of choroidal neovascularization (CNV) event occurrence in eyes with dry age-related macular degeneration (AMD). DESIGN:Prospective observational study. PARTICIPANTS:A total of 513 participants (844 eyes) followed ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.02.048

    authors: Friberg TR,Bilonick RA,Brennen PM

    更新日期:2012-07-01 00:00:00

  • Complex microcirculation patterns detected by confocal indocyanine green angiography predict time to growth of small choroidal melanocytic tumors: MuSIC Report II.

    abstract:PURPOSE:Multiple independent laboratories have confirmed the histologic observation that some tumor microcirculation patterns (MCPs) in uveal melanomas are associated strongly with death resulting from metastatic disease. Because these patterns are imageable with confocal indocyanine green angiography (ICG), we designe...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0161-6420(02)01266-6

    authors: Mueller AJ,Freeman WR,Schaller UC,Kampik A,Folberg R

    更新日期:2002-12-01 00:00:00

  • Ocular BB injuries.

    abstract::Data from the United States Consumer Product Safety Commission indicate that air-powered guns were responsible for 22,800 injuries treated in emergency rooms during 1981, of which 1255 were eye injuries. From 1970 to 1981, 32 patients have undergone surgical intervention at the Wilmer Eye Institute for airgun-related ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34159-8

    authors: Sternberg P Jr,de Juan E Jr,Green WR,Hirst LW,Sommer A

    更新日期:1984-10-01 00:00:00

  • Combined cataract extraction with intraocular lens implant and mitomycin-augmented trabeculectomy.

    abstract:PURPOSE:Cataract and glaucoma commonly coexist in elderly patients and present complex treatment options. This study investigates the results of simultaneous treatment of both conditions using phacoemulsification with posterior chamber lens implant and mitomycin-augmented trabeculectomy (combined surgery). METHODS:A r...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(96)30571-x

    authors: Lederer CM Jr

    更新日期:1996-07-01 00:00:00

  • Clinicopathologic effects of mutant GUCY2D in Leber congenital amaurosis.

    abstract:PURPOSE:To study the retinal degeneration in an 11 -year-old patient with Leber congenital amaurosis (LCA) caused by mutation in GUCY2D. STUDY DESIGN:Comparative human tissue study. PARTICIPANTS:Two subjects with LCA; postmortem eye from one LCA patient and three normal donors. METHODS:Clinical and visual function s...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(02)01757-8

    authors: Milam AH,Barakat MR,Gupta N,Rose L,Aleman TS,Pianta MJ,Cideciyan AV,Sheffield VC,Stone EM,Jacobson SG

    更新日期:2003-03-01 00:00:00

  • Glutamic acid decarboxylase autoantibody prevalence and association with HLA genotype in patients with younger-onset type 1 diabetes and proliferative diabetic retinopathy.

    abstract:OBJECTIVE:To investigate the relationship of HLA status and autoantibodies to glutamic acid decarboxylase (GAD) in proliferative diabetic retinopathy (PDR) to assess the role of autoimmunity and genetic markers in retinopathy. DESIGN:Retrospective, nonrandomized, comparative study. PARTICIPANTS:Patients who had suffe...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2005.05.016

    authors: Mimura T,Funatsu H,Uchigata Y,Kitano S,Shimizu E,Amano S,Yamagami S,Noma H,Araie M,Hori S

    更新日期:2005-11-01 00:00:00

  • Modified grid argon (blue-green) laser photocoagulation for diffuse diabetic macular edema.

    abstract::One hundred sixty eyes of 92 patients with diffuse diabetic maculopathy with or without cystoid macular edema were enrolled in a prospective randomized clinical trial to determine the efficacy of "modified grid" argon (blue-green) laser photocoagulation. At the 12- and 24-month follow-ups, visual acuity significantly ...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(86)33638-8

    authors: Olk RJ

    更新日期:1986-07-01 00:00:00

  • Rapid growth of an optic nerve ganglioglioma in a patient with neurofibromatosis 1.

    abstract:BACKGROUND:Optic nerve gangliogliomas are extremely rate tumors of the central nervous system composed of elements of glial and neuronal origin. The clinical and biologic behavior of gangliogliomas depends on the glial component. Pilocytic gangliogliomas generally have a low growth rate and good ultimate prognosis. No ...

    journal_title:Ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1016/s0161-6420(96)30613-1

    authors: Sadun F,Hinton DR,Sadun AA

    更新日期:1996-05-01 00:00:00

  • Role of instrument cleaning and maintenance in the development of diffuse lamellar keratitis.

    abstract:OBJECTIVE:To determine if instrument cleaning techniques affect the rate of diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK). DESIGN:Retrospective case series. PARTICIPANTS:Two hundred ten eyes of 109 patients. METHODS:A record review was performed of all patients who underwent LASIK at th...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(01)00876-4

    authors: Yuhan KR,Nguyen L,Wachler BS

    更新日期:2002-02-01 00:00:00

  • Surgical outcomes in patients with bilateral ptosis and Hering's dependence.

    abstract:PURPOSE:To assess whether sequential or simultaneous ptosis repair yields a better postoperative outcome in patients with documented preoperative Hering's dependency. DESIGN:Retrospective, case-control study. PARTICIPANTS AND CONTROLS:Of the 216 patients who underwent bilateral ptosis surgery, 109 patients with docum...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2011.07.008

    authors: Cetinkaya A,Kersten RC

    更新日期:2012-02-01 00:00:00

  • The changing spectrum of fungal keratitis in south Florida.

    abstract:PURPOSE:To review the clinical experience with fungal keratitis in south Florida over a 10-year period. METHODS:One hundred twenty-five cases of fungal keratitis were identified in the microbiology laboratory records between January 1982 and January 1992. The medical record of each patient was reviewed. RESULTS:The m...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(94)31225-5

    authors: Rosa RH Jr,Miller D,Alfonso EC

    更新日期:1994-06-01 00:00:00

  • Nanophthalmic sclera. Morphologic and tissue culture studies.

    abstract::We performed morphologic and tissue culture studies on scleral tissues obtained from a nanophthalmic patient. Seen by light and electron microscopy, collagens in these unusually thick scleral tissues were arranged in irregularly interlacing bundles. The size of the collagen fibers was more variable than that observed ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(86)33704-7

    authors: Yue BY,Duvall J,Goldberg MF,Puck A,Tso MO,Sugar J

    更新日期:1986-04-01 00:00:00

  • Penetrating ocular injuries. Types of injuries and visual results.

    abstract::The authors studied the hospital records of 453 patients who underwent primary surgical repair of penetrating ocular injuries at the Wilmer Institute from January 1970 through December 1981. The injury was due to blunt force in 22%, a sharp laceration in 37%, and a missile in 41%. The following factors correlated with...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(83)34387-6

    authors: De Juan E Jr,Sternberg P Jr,Michels RG

    更新日期:1983-11-01 00:00:00

  • Five years' follow-up in the surgical management of cataracts in high myopia treated with the Kelman phacoemulsification technique.

    abstract::With the advent of phacoemulsification, much interest has again been rekindled in extracapsular cataract surgery and its effects on the vitreoretinopathies associated in high myopia. Since 1972, 278 patients with high myopia greater than --7.50 D, as as determined by axial length echography, have been operated on by t...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(79)35313-1

    authors: Praeger DL

    更新日期:1979-11-01 00:00:00

  • Antibiotic resistance patterns of ocular bacterial flora: a prospective study of patients undergoing anterior segment surgery.

    abstract:PURPOSE:To determine the antibiotic susceptibility patterns of conjunctival bacterial flora isolated preoperatively from patients undergoing anterior segment surgery. DESIGN:Prospective observational study. PARTICIPANTS:One hundred fifty-six eyes from 139 patients scheduled for anterior segment surgery were enrolled ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(03)00735-8

    authors: Ta CN,Chang RT,Singh K,Egbert PR,Shriver EM,Blumenkranz MS,Miño de Kaspar H

    更新日期:2003-10-01 00:00:00

  • Fellow eye findings of highly myopic subjects operated for retinal detachment associated with a macular hole.

    abstract:PURPOSE:To identity anatomic risk factors involved in the onset of retinal complications causing decrease of visual acuity (VA) in the fellow eyes of highly myopic patients operated for retinal detachment with macular hole (RDMH). DESIGN:Cohort study. PARTICIPANTS:Ninety-eight patients (mean age, 51.5+/-8.0 years) wi...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2008.02.016

    authors: Ripandelli G,Coppé AM,Parisi V,Stirpe M

    更新日期:2008-09-01 00:00:00

  • Clinical and Genetic Characteristics of Japanese Patients with Age-Related Macular Degeneration and Pseudodrusen.

    abstract:PURPOSE:To investigate differences in clinical characteristics and genotype distribution in Japanese patients with age-related macular degeneration (AMD) and pseudodrusen using multimodal imaging. DESIGN:Retrospective, observational case series. PARTICIPANTS:A total of 101 patients (101 eyes) with AMD and pseudodruse...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2016.06.052

    authors: Elfandi S,Ooto S,Ueda-Arakawa N,Takahashi A,Yoshikawa M,Nakanishi H,Tamura H,Oishi A,Yamashiro K,Yoshimura N

    更新日期:2016-10-01 00:00:00