Abstract:
OBJECTIVES:The purpose of this study was to clarify clinical and angiographical characteristics of acetylcholine (ACh)-induced spasm in the right and left coronary artery. METHODS AND RESULTS:We performed 557 consecutive procedures of spasm provocation tests of ACh from January 1991 to December 2000 in patients without significant stenosis. ACh was injected in incremental doses of 20, 50 and 80 microg into the right coronary artery and in incremental doses of 20, 50 and 100 microg into the left coronary artery if spasm had not been provoked. Coronary spasm was defined as positive with more than 99% transient luminal narrowing. Proximal spasm was defined as that of segments 1, 2, 5, 6, 7 and 11 and distal spasm as that of segments 3, 4, 8, 9, 12, 13 and 14. Low-ACh-dose-induced spasms showed the clinical findings and angiographical characteristics of higher incidence of variant angina, proximal spasms, focal spasms, more ST elevation and ischemic heart disease. In contrast, angiographical characteristics of high-Ach-dose-induced spasms were distal spasms and diffuse spasms and there was less variant angina and less ST elevation. CONCLUSIONS:Lower ACh doses induced spasms more proximally and focally in the coronary artery, while higher doses of ACh provoked spasms more distally and diffusely.
journal_name
Coron Artery Disjournal_title
Coronary artery diseaseauthors
Sueda S,Kohno H,Fukuda H,Inoue K,Suzuki J,Watanabe K,Ochi T,Uraoka Tdoi
10.1097/00019501-200206000-00005subject
Has Abstractpub_date
2002-06-01 00:00:00pages
231-6issue
4eissn
0954-6928issn
1473-5830journal_volume
13pub_type
杂志文章abstract:BACKGROUND:P-selectin, an adhesion molecule of the selectin family, is expressed on the surface of activated thrombocytes by thrombin. The aim of the present study was to assess the predictive value of P-selectin (estimated by flow cytometric assay) for acute cardiac events in acute coronary syndrome. METHODS:The stud...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199508000-00009
更新日期:1995-08-01 00:00:00
abstract:INTRODUCTION:The serum level of parathyroid hormone (PTH) has been shown to be a predictor of cardiovascular mortality. Data on the association between PTH level and degree of atherosclerosis severity are lacking. The objective of this study was to determine the relationship of serum PTH level and number of stenotic co...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000089
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Electrogram fractionation can result when multiple groups of cardiac cells are excited asynchronously within the recording region of a mapping electrode. The spatial resolution of an electrode thus plays an important role in mapping complex rhythms. METHODS:We used a computational model, validated against e...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3283507a9b
更新日期:2012-03-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200103000-00005
更新日期:2001-03-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200012000-00008
更新日期:2000-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000094
更新日期:2014-08-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199302000-00009
更新日期:1993-02-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e32833578f4
更新日期:2010-05-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e328011ac01
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e328035f8ae
更新日期:2007-06-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199612000-00002
更新日期:1996-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/00019501-200609000-00011
更新日期:2006-09-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e32832fe5d5
更新日期:2010-08-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3282f0a2a7
更新日期:2007-12-01 00:00:00
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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doi:10.1097/MCA.0000000000000150
更新日期:2014-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000983
更新日期:2020-11-13 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/00019501-199909000-00008
更新日期:1999-09-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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doi:10.1097/MCA.0b013e3283576a77
更新日期:2012-09-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199502000-00009
更新日期:1995-02-01 00:00:00
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journal_title:Coronary artery disease
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更新日期:2014-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200002000-00013
更新日期:2000-02-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章,评审
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更新日期:2017-08-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2005-11-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200302000-00010
更新日期:2003-02-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章,多中心研究
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更新日期:2016-08-01 00:00:00