Buccal misoprostol as cervical preparation for second trimester pregnancy termination.

Abstract:

:The objective of the study was to assess the efficacy of cervical preparation with misoprostol or laminaria suction abortion up to 18 weeks gestation. The study was conducted among a consecutive case series of patients presenting for dilatation and evacuation at a single center. Cervical preparation was effected by either 600 mg buccal misoprostol (n = 32) or laminaria (n = 78). Dilatation and evacuation was then performed using vacuum aspiration, with fetal parts or placenta removed as necessary with appropriate forceps. The principle outcome of interest was procedure time. Complete abortion was effected in 100% of the cases. In all cases, the cervix was adequately prepared to allow either the introduction of a size 14-mm suction cannula or was easily dilated to this diameter. Group size was sufficient for detection of a 20% difference in mean procedure time with 80% power (calculated with two separate standard deviations for procedure time). Procedure times were not significantly different when misoprostol was used compared to laminaria for cervical preparation. It is concluded that the use of misoprostol to provide cervical preparation in second trimester abortion procedures appeared effective and offers an alternative to laminaria. Buccal misoprostol should be more widely investigated for this purpose.

journal_name

Contraception

journal_title

Contraception

authors

Todd CS,Soler M,Castleman L,Rogers MK,Blumenthal PD

doi

10.1016/s0010-7824(02)00306-2

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

415-8

issue

6

eissn

0010-7824

issn

1879-0518

pii

S0010782402003062

journal_volume

65

pub_type

杂志文章
  • The effects of gossypol on nuclear protein in rat testes. II. The synthesis of histones and testis-specific proteins after gossypol treatment.

    abstract::This communication is to report the effects of gossypol on the synthesis of chromosomal basic proteins in the spermiogenic cells. A double-labelling experiment has been performed. The control rats received 14C-arginine, whereas the gossypol-treated rats received a 3H-arginine injection. An equal volume of the tissues ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(88)90031-5

    authors: Teng CS,Fei RR

    更新日期:1988-03-01 00:00:00

  • Efficacy and safety of medical abortion using mifepristone and buccal misoprostol through 63 days.

    abstract:OBJECTIVE:The aim of this study was to report on the safety and efficacy of an evidence-based medical abortion regimen utilizing 200 mg of mifepristone orally followed by home use of 800 mcg misoprostol buccally 24-48 h later through 63 days estimated gestational age. STUDY DESIGN:We analyzed outcomes in women present...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2015.01.005

    authors: Gatter M,Cleland K,Nucatola DL

    更新日期:2015-04-01 00:00:00

  • Removal of deeply inserted, nonpalpable levonorgestrel (Norplant) implants.

    abstract::Deeply inserted, nonpalpable contraceptive implants can often be removed easily using 6-8 cm3 of 1% lidocaine and a single 1 cm incision. There is no need for suturing of the incision. The location of nonpalpable implants not retrieved by this procedure can be determined by a plain, soft tissue x-ray (standard AP and ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(96)00004-2

    authors: Sarma SP,Wamsher JG,Whitlock SW

    更新日期:1996-03-01 00:00:00

  • Perfect-use and typical-use Pearl Index of a contraceptive mobile app.

    abstract:OBJECTIVES:The Natural Cycles application is a fertility awareness-based contraceptive method that uses dates of menstruation and basal body temperature to inform couples whether protected intercourse is needed to prevent pregnancies. Our purpose with this study is to investigate the contraceptive efficacy of the mobil...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2017.08.014

    authors: Berglund Scherwitzl E,Lundberg O,Kopp Kallner H,Gemzell Danielsson K,Trussell J,Scherwitzl R

    更新日期:2017-12-01 00:00:00

  • Quick start: novel oral contraceptive initiation method.

    abstract::Conventional oral contraceptive (OC) starting instructions require waiting until menses to begin the OC. The conventional approach requires detailed patient education about when to begin and also may require the use of less effective or less acceptable interim contraceptive protection until menses. At our urban family...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(02)00351-7

    authors: Westhoff C,Kerns J,Morroni C,Cushman LF,Tiezzi L,Murphy PA

    更新日期:2002-09-01 00:00:00

  • A comparative study on the effects of a monophasic pill containing desogestrel plus 20 micrograms ethinylestradiol, a triphasic combination containing levonorgestrel and a monophasic combination containing gestodene on coagulatory factors.

    abstract::The changes in haemostasis during oral contraception are related to the ethinylestradiol dose present in the formulation taken by the patient. An open, randomized longitudinal study was performed to evaluate and compare the effects that low-dose oral contraceptives (OCs) containing different doses of ethinylestradiol ...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(91)90123-w

    authors: Melis GB,Fruzzetti F,Nicoletti I,Ricci C,Lammers P,Atsma WJ,Fioretti P

    更新日期:1991-01-01 00:00:00

  • Trends in nonresident abortion rates in New York City from 2005 to 2015: a time series analysis.

    abstract:OBJECTIVES:To examine trends and utilization patterns of NYC abortion services by nonresidents since growing abortion restrictions across many states could drive women to seek care in less restrictive jurisdictions including NYC. STUDY DESIGN:We used data from Induced Termination of Pregnancy certificates filed with t...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2019.05.008

    authors: Johansson EW,Argov EL,Langston A,Yager A,Searing H,Liu SY

    更新日期:2019-09-01 00:00:00

  • Contraceptive knowledge and use among low-income Hispanic immigrant women and non-Hispanic women.

    abstract:BACKGROUND:With the rising influx of Hispanics to the United States, there is an ongoing need to promote health and wellness care to this non-English-speaking, minority population group. Programs, specifically developed to address the unique cultural mores of Hispanics, need to focus on increasing knowledge about healt...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2007.12.008

    authors: Garcés-Palacio IC,Altarac M,Scarinci IC

    更新日期:2008-04-01 00:00:00

  • Levels of contraceptive seroids in breast milk and plasma of lactating women.

    abstract::Levels of contraceptive steroids in breast milk and plasma of lactating women were investigated. 7 lactating women received 150 mg medroxyprogesterone acetate (MPA) 1 week after delivery. 5 women (lactating) took 350 mcg norethisterone (NET) and 2 took 150 mcg d-norgestrel (d-ng) + 30 mcg ethinyl estradiol. Milk an...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(77)90061-0

    authors: Saxena BN,Shrimanker K,Grudzinskas JG

    更新日期:1977-12-01 00:00:00

  • Vaginal misoprostol compared with vaginal gemeprost in termination of second trimester pregnancy. A randomized trial.

    abstract::A prospective randomized trial was conducted in 140 women to compare the efficacy of vaginal gemeprost with vaginal misoprostol for termination of second trimester pregnancy. Women requesting termination of second trimester pregnancy were randomized into two groups. Group A women were given 1 mg vaginal gemeprost ever...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0010-7824(98)00099-7

    authors: Wong KS,Ngai CS,Wong AY,Tang LC,Ho PC

    更新日期:1998-10-01 00:00:00

  • Effects of combined oral contraceptives, depot medroxyprogesterone acetate and the levonorgestrel-releasing intrauterine system on the vaginal microbiome.

    abstract:OBJECTIVES:Prior studies suggest that the composition of the vaginal microbiome may positively or negatively affect susceptibility to sexually transmitted infections (STIs) and bacterial vaginosis (BV). Some female hormonal contraceptive methods also appear to positively or negatively influence STI transmission and BV....

    journal_title:Contraception

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.contraception.2016.11.006

    authors: Brooks JP,Edwards DJ,Blithe DL,Fettweis JM,Serrano MG,Sheth NU,Strauss JF 3rd,Buck GA,Jefferson KK

    更新日期:2017-04-01 00:00:00

  • In vitro inhibition of sperm motility by some local mineral water drinks.

    abstract::The effect of eight common local mineral water drinks in Ile-Ife, Nigeria (seven cola and one lemon-based) on sperm motility in vitro was carried out. There was no significant difference in the pH values of all the drinks, the pH ranged between 2.30-2.50. After one minute, Pepsi-Cola had the least inhibitory effect on...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(87)90092-8

    authors: Oyelola OO,Ayangade SO,Amole F

    更新日期:1987-10-01 00:00:00

  • Weight and body mass index among female contraceptive clients.

    abstract:OBJECTIVES:As obesity may affect the efficacy of some contraceptives, we examined weight, body mass index (BMI) and prevalence of obesity among female contraceptive clients at 231 U.S. health centers. A secondary aim was to analyze differences in contraceptive method use by obesity status. STUDY DESIGN:Cross-sectional...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2015.02.006

    authors: Kohn JE,Lopez PM,Simons HR

    更新日期:2015-06-01 00:00:00

  • A comparative study of the levonorgestrel-releasing intrauterine system Mirena versus the Copper T380A intrauterine device during lactation: breast-feeding performance, infant growth and infant development.

    abstract:BACKGROUND:Mirena is a levonorgestrel-releasing intrauterine system (LNG-IUS) that provides highly effective and long-acting progestogen-only contraception. OBJECTIVE:The objective of this study was to analyze the possible effects of using LNG-20 microg IUS on breast-feeding performance, infant growth and infant devel...

    journal_title:Contraception

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.contraception.2005.04.004

    authors: Shaamash AH,Sayed GH,Hussien MM,Shaaban MM

    更新日期:2005-11-01 00:00:00

  • Pharmacokinetic study of orally administered RU 486 in non-pregnant women.

    abstract::A method based on HPLC was devised for the estimation of RU 486 in blood and utilised to study the pharmacokinetics of a single dose of 50 mg RU 486 administered orally to 12 women on day 7 of the cycle. The dose was rapidly absorbed with peak plasma concentration between 1 and 2 hours. Distribution was also rapid (me...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(89)90052-8

    authors: He CH,Shi YE,Ye ZH,Zhang GG,Jiang NX,Van Look PF,Fotherby K

    更新日期:1989-10-01 00:00:00

  • Medroxyprogesterone acetate levels among Kenyan women using depot medroxyprogesterone acetate in the FEM-PrEP trial.

    abstract:OBJECTIVE:To describe medroxyprogesterone acetate (MPA) levels among Kenyan depot medroxyprogesterone acetate (DMPA) users in the FEM-PrEP HIV prevention trial, and to compare MPA levels between ARV for HIV prevention (treatment) and placebo groups. STUDY DESIGN:We measured MPA in previously collected plasma samples f...

    journal_title:Contraception

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.contraception.2016.03.003

    authors: Nanda K,Callahan R,Taylor D,Wang M,Agot K,Jenkins D,Van Damme L,Dorflinger L,FEM-PrEP Study Group.

    更新日期:2016-07-01 00:00:00

  • Vaginal swab specimen processing methods influence performance of rapid semen detection tests: a cautionary tale.

    abstract:BACKGROUND:Detection of semen biomarkers in vaginal fluid can be used to assess women's recent exposure to semen. Quantitative tests for detection of prostate-specific antigen (PSA) perform well, but are expensive and require specialized equipment. We assessed two rapid immunochromatographic strip tests for identificat...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2010.02.022

    authors: Hobbs MM,Steiner MJ,Rich KD,Gallo MF,Warner L,Macaluso M

    更新日期:2010-09-01 00:00:00

  • Etonogestrel implant migration to the vasculature, chest wall, and distant body sites: cases from a pharmacovigilance database.

    abstract:OBJECTIVE:To describe clinical outcomes of etonogestrel implant patients with migration to the vasculature, chest wall and other distant body sites spontaneously reported to the US Food and Drug Administration Adverse Event Reporting System (FAERS) database. STUDY DESIGN:We performed a standardized Medical Dictionary ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2017.08.009

    authors: Kang S,Niak A,Gada N,Brinker A,Jones SC

    更新日期:2017-12-01 00:00:00

  • Corrosion behavior of Cu and the Cu-Zn-Al shape memory alloy in simulated uterine fluid.

    abstract::Chemical immersion tests, electrochemical methods and atomic absorption spectrometry were employed to investigate the corrosion behavior of Cu and the Cu-Zn-Al shape memory alloy (SMA) in simulated uterine fluid. The effect of pH on corrosion rate and corrosion potential was also investigated. The results indicated th...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2005.04.006

    authors: Chen B,Liang C,Fu D,Ren D

    更新日期:2005-09-01 00:00:00

  • Contraception technology: past, present and future.

    abstract::Steady progress in contraception research has been achieved over the past 50 years. Hormonal and nonhormonal modern contraceptives have improved women's lives by reducing different health conditions that contributed to considerable morbidity. However, the contraceptives available today are not suitable to all users, a...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2012.08.002

    authors: Sitruk-Ware R,Nath A,Mishell DR Jr

    更新日期:2013-03-01 00:00:00

  • Do as we say, not as we do: experiences of unprotected intercourse reported by members of the Society of Family Planning.

    abstract:OBJECTIVES:We examine the lifetime and past-year prevalence and circumstances of unprotected intercourse among members of the Society of Family Planning (SFP), a professional reproductive health organization in the United States. STUDY DESIGN:We invited the membership of SFP (n=477) via email to participate in an anon...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2015.04.004

    authors: Aiken AR,Trussell J

    更新日期:2015-07-01 00:00:00

  • Combined oral contraceptives: do we know all of their effects?

    abstract::Combined oral contraceptives are undoubtedly popular. By the end of the 1980's, an estimated 63 million married women around the world were using this method of contraception. In Britain, perhaps 95% of all sexually active women have used the pill at some time before their 30th birthday. Commensurate with such widespr...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/0010-7824(95)00095-r

    authors: Hannaford PC

    更新日期:1995-06-01 00:00:00

  • Effect of a new injectable male contraceptive on the seminal plasma amino acids studied by proton NMR spectroscopy.

    abstract::Effect of RISUG, a newly developed male contraceptive, on various amino acids of seminal plasma ejaculates was studied by proton magnetic resonance spectroscopy at 400 MHz. Levels of amino acids were compared with the seminal plasma of obstructive azoospermia and controls. Glutamic acid, glutamine, and arginine were f...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(02)00343-8

    authors: Chaudhury K,Sharma U,Jagannathan NR,Guha SK

    更新日期:2002-09-01 00:00:00

  • Fertility regulation in male rats and hamsters with alkylating agents.

    abstract::A single intratesticular injection of TEPA or Thio-TEPA induced a period of infertility lasting 1-2 months. Restoration of fertility was characterized by a reduction of the litter size resulting from the first inpregnation post-treatment. There was no evidence of tissue pathogenesis 6-12 months after treatment. ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(80)90061-x

    authors: Howe GR,Steward R

    更新日期:1980-08-01 00:00:00

  • Complications of surgical termination of second-trimester pregnancy in obese versus nonobese women.

    abstract:BACKGROUND:Obesity is becoming increasingly common in obstetric and gynecologic populations, which may affect the safety of surgical termination of pregnancy. STUDY DESIGN:We performed a retrospective review of all patients undergoing second-trimester surgical termination of pregnancy by under ultrasound guidance term...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2012.02.006

    authors: Murphy LA,Thornburg LL,Glantz JC,Wasserman EC,Stanwood NL,Betstadt SJ

    更新日期:2012-10-01 00:00:00

  • Elevated blood pressure following LHRH antagonists in rats.

    abstract::LHRH and three potent antagonistic analogs: z-[Gln1, des-His2,D-Pse6,des-Gly10]-LHRH ethylamide, where D-Pse = threo-D-phenylserine; z-[Gln1,des-His2,D-Phe6,des-Gly10]-LHRH ethylamide; and Boc-[Ser(Bzl)1,des-His2,D-Trp6]-LHRH; were studied for their effects on blood pressure and heart rate in chronically catheterized ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(82)90096-8

    authors: Smith RD,Edgren RA

    更新日期:1982-04-01 00:00:00

  • Abortion referral-making in the United States: findings and recommendations from the abortion referrals learning community.

    abstract::In recent years, reproductive health researchers and practitioners have increased their focus on abortion referrals as an overlooked component of access. March 2019 proposed changes to the regulation of publicly funded family planning services that severely restrict abortion referrals have heightened public attention....

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2019.07.141

    authors: Zurek M,O'Donnell J

    更新日期:2019-11-01 00:00:00

  • Intrauterine contraception with copper and with levonorgestrel: a randomized study of the TCu 380Ag and levonorgestrel 20 mcg/day devices.

    abstract::First year results of a randomized study of 1509 users of the Copper T380Ag with a silver core or of an IUD releasing 20 mcg day of levonorgestrel are reported. The cumulative gross pregnancy rate for each device was 0.3 per 100 at one year, with more than 490 women having one year of use with each device. The levonor...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(84)90036-2

    authors: Sivin I,Alvarez F,Diaz J,Diaz S,el Mahgoub S,Coutinho E,Brache V,Diaz MM,Faundes A,Pavez M

    更新日期:1984-11-01 00:00:00

  • Effect of an oral contraceptive in primary dysmenorrhea--changes in uterine activity and reactivity to agonists.

    abstract::Mechanisms for the therapeutic effect of oral contraceptives in dysmenorrhea were studied by recording intrauterine pressure on the first day of menstrual bleeding in women with moderate to severe symptoms and after three weeks of oral contraceptive therapy (150 micrograms levonorgestrel + 30 micrograms ethinyl estrad...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(89)90026-7

    authors: Ekström P,Juchnicka E,Laudanski T,Akerlund M

    更新日期:1989-07-01 00:00:00

  • Effectiveness of levonorgestrel emergency contraception given before or after ovulation--a pilot study.

    abstract:BACKGROUND:Although widely used, the mechanisms of action of the levonorgestrel emergency contraceptive pill (LNG ECP) are still unclear. There are increasing data to indicate that LNG is particularly effective as an ECP by interrupting follicular development and ovulation. An important outstanding question is whether ...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/j.contraception.2006.08.015

    authors: Novikova N,Weisberg E,Stanczyk FZ,Croxatto HB,Fraser IS

    更新日期:2007-02-01 00:00:00