Abstract：
BACKGROUND AND OBJECTIVE:Drug mixtures containing sufentanil may be unstable owing to absorption into the drug reservoirs of patient-controlled epidural analgesia systems that contain polyvinylchloride. The stability of sufentanil in a mixture of ropivacaine 0.2% in a 750 mL reservoir was therefore investigated. METHODS:During simulated epidural infusions of 5 mLh(-1) at 25 degrees C, sufentanil concentrations were measured for 96 h. Samples were taken from the reservoir and from the end of the epidural catheter under the following conditions: into glass or polyvinylchloride reservoirs containing ropivacaine 0.2% with sufentanil 1, 0.75 or 0.5 microg mL(-1); and into polyvinylchloride reservoirs with ropivacaine 0.2% and sufentanil 1 microg mL(-1) which were stored for 4 weeks at 8 degrees C. RESULTS:The different solutions remained stable over the observation period of 96 h. Using the same solutions, independent samples' ANOVA showed no difference in the sufentanil concentrations between the glass and polyvinylchloride reservoirs, or between the polyvinylchloride reservoirs when stored for 4 weeks. Correlations between the concentrations at the different measurement times were extremely high for the reservoir (r(min) = 0.98, r(max) = 1.00) and the catheter end (rmin = 0.86, r(max) = 1.00). CONCLUSIONS:Sufentanil citrate at 0.5-1.0 microg mL(-1) in an admixture of ropivacaine 0.29 for 5 days, which is the usual period for postoperative epidural analgesia, remains stable in a polyvinylchloride reservoir. There is no change in the drug concentration even if the reservoir is stored for 4 weeks at 8 degrees C.
journal_name
Eur J Anaesthesioljournal_title
European journal of anaesthesiologyauthors
Brodner G,Ermert T,Van Aken H,Westphal M,Marcus MA,Gogarten W,Goeters C,Bürkle Hdoi
10.1017/s0265021502000479subject
Has Abstractpub_date
2002-04-01 00:00:00pages
295-7issue
4eissn
0265-0215issn
1365-2346journal_volume
19pub_type
杂志文章abstract：:Stellate ganglion block is a selective sympathetic block that affects the ipsilateral head, neck, upper extremity and upper part of the thorax. Convulsions are a recognized complication of intra-arterial injection during stellate ganglion block. As central nervous system toxicity depends ultimately on the concentratio...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,评审
doi：10.1017/s0265021502000613
更新日期：2002-05-01 00:00:00
abstract：:In a multicentre, randomized, double-blind, placebo-controlled dose-ranging study, 1030 patients undergoing outpatient surgery with general anaesthesia received i.v. dolasetron mesylate (12.5, 25, 50, or 100 mg) or placebo. The principal outcome measure was the proportion of patients who were free of emesis or rescue ...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1046/j.1365-2346.2000.00594.x
更新日期：2000-01-01 00:00:00
abstract：:Malignant hyperthermia is an autosomal-dominant inherited disorder of the skeletal muscle cell characterized by a hypermetabolic response to all commonly used inhalational anaesthetics and depolarizing muscle relaxants. The clinical syndrome includes muscle rigidity, hypercapnia, tachycardia and myoglobinuria as resul...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,评审
doi：10.1046/j.1365-2346.2001.00888.x
更新日期：2001-10-01 00:00:00
abstract：:The thrombogenicity of polyethylene, silicone and polyurethane central venous catheters was compared in a prospective clinical, phlebographic and post-mortem study in 52 patients. The incidence of central venous thrombosis was high with polyethylene catheters (70%), but much lower with silicone (20%) and with polyuret...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1984-12-01 00:00:00
abstract：:Dantrolene plasma concentrations and renal clearance calculations in a patient undergoing major surgery are reported. The family history was positive for malignant hyperthermia. Following oral pretreatment the plasma concentrations in this patient were not noticeably different from values obtained in a study in awake ...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章
doi：
更新日期：1986-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Hypotension, the commonest side-effect of spinal anaesthesia, results from sympathetic denervation. This study compared patient positioning (supine vs. decubitus) on haemodynamic variables during spinal anaesthesia. METHODS:After intravenous crystalloid preloading with 5 mL kg(-1), hyperbaric ...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1017/s0265021505001183
更新日期：2005-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:the objective of this study was to assess whether antiemetic drugs metoclopramide and diphenhydramine, administered together as opposed to alone, can have better efficacy in preventing postoperative nausea and vomiting when added to patient-controlled morphine analgesia. PATIENTS AND METHODS:d...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1097/EJA.0b013e32833f53b8
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Magnesium sulphate is an important adjuvant drug in multimodal anaesthesia. In combination with rocuronium it can enhance neuromuscular blockade (NMB). Limited data exist concerning the effect of magnesium sulphate on the duration of deep or intense NMB and the period of no response. OBJECTIVE(S):To determi...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1097/EJA.0000000000001003
更新日期：2019-07-01 00:00:00
abstract：:Dynamic hyperinflation, also called intrinsic PEEP (PEEPi,) occurs particularly when high tidal volumes or high respiratory rates are used during mechanical ventilation, although the phenomenon does occur at normal tidal volumes. It is not identified using existing monitoring such as the airway pressure but can be ide...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:Simulation is often used for training personnel in activities where the consequences of inappropriate actions are serious. We report a realistic training simulator, which can reproduce practically all potential malfunctions in the anaesthetic machine. Using actual standard equipment (Dameca 10750), the interior of the...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The efficiency of bilateral paravertebral blockade combined with general anaesthesia (active) vs. general anaesthesia alone (control) in reducing postoperative pain following laparoscopic cholecystectomy was evaluated using a prospective randomized study design. METHODS:Patients were randomly ...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1017/s026502150400612x
更新日期：2004-06-01 00:00:00
abstract：:A hemiarthroplasty for femoral neck fracture was successfully performed under combined epidural anaesthesia and light general anaesthesia before phaeochromocytoma removal. Pre-operative therapy was managed with doxazosin, enalapril and diltiazem. Peri-operative management facilitated maintenance of stable haemodynamic...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:In this review, we shall consider the oral and intravenous fluid management of pregnant women during labour and operative delivery in the context of neuroaxial blockade. We shall also discuss the use of blood transfusion in the peripartum period, especially during postpartum haemorrhage. Current management of military...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,评审
doi：10.1097/EJA.0b013e32833c30e3
更新日期：2010-12-01 00:00:00
abstract：:Propofol and isoflurane were compared for haemodynamic stability and recovery time as main anaesthetic agents for maintenance in a total of 43 ASA I and II patients in uncomplicated operations lasting at least 30 min. The premedication (oral diazepam), induction (thiopentone-fentanyl-suxamethonium) and maintenance pro...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Patients in cardiac surgery and critically ill patients often demonstrate either hypothermia or fever. In addition, owing to heart failure, they frequently require inotropic support. The relative effectiveness of modern inotropic agents at various temperatures has not yet been evaluated. Theref...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章
doi：10.1097/EJA.0b013e328330e9a0
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Randomised controlled trial (RCT) abstracts published in journal articles have traditionally been deficient of crucial information. To improve the quality of RCT abstracts, in January 2008, the Consolidated Standards of Reporting Trial (CONSORT) group published a checklist of essential informat...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章
doi：10.1097/EJA.0b013e32833fb96f
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To evaluate the efficacy of 0.1% ropivacaine with fentanyl 2 microg mL(-1) via epidural for analgesia in labour. METHODS:In a randomized study, 80 nulliparous parturients in labour had epidural analgesia initiated with 0.2% ropivacaine and fentanyl and were then randomized to receive either 0....
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1017/s0265021504000031
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND:Patient blood management (PBM) can prevent preoperative anaemia, but little is known about practice in Europe. OBJECTIVE:To assess the pre and postoperative prevalence and perioperative management of anaemia in patients undergoing elective orthopaedic surgery in Europe. DESIGN:An observational study; data ...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,多中心研究
doi：10.1097/EJA.0000000000000202
更新日期：2015-03-01 00:00:00
abstract：:The initial disposition of propofol was reported to change when the administration was preceded by fentanyl. The pharmacokinetic profile of the induction dose of propofol (2 mg kg-1 body weight) was studied in 20 ASA I patients randomly allocated to receive fentanyl 1.5 microgram kg-1 (n = 12) or not (n = 8). Anaesthe...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In most studies of cardiac output changes after spinal anaesthesia, the time-resolution is limited. The aim of this study was to demonstrate cardiac output changes with high time-resolution during onset of spinal anaesthesia in elderly patients. METHODS:We investigated 32 patients aged 60 yr s...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章
doi：10.1017/S0265021507000427
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The laryngeal mask has become a widely accepted alternative to endotracheal intubation and mask ventilation. The laryngeal tube is a relatively new supraglottic airway device for airway management. We compared the new version of the laryngeal tube with the laryngeal mask. METHODS:In a randomiz...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1017/S0265021507000129
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:In this prospective, randomized, double-blind, controlled study, we investigated the sensory, motor and analgesic block characteristics of S(+) ketamine, fentanyl and saline given intrathecally (IT) in addition to 0.5% plain bupivacaine (10 mg) for spinal analgesia. METHODS:Ninety ASA I or II adult patients...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1017/S0265021506000950
更新日期：2006-12-01 00:00:00
abstract：:One hundred patients undergoing scheduled upper limb orthopaedic surgery were studied to determine if the speed of injection of the local anaesthetic solution could modify the extent and depth of anaesthesia with the axillary approach to the brachial plexus. The blocks were performed using the 'orthogonal two-needle t...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Preoperative oral dextromethorphan and intravenous clonidine attenuate arterial pressure and heart rate increases during tourniquet inflation under general anaesthesia. The effect of preoperative oral clonidine on these variables has not been investigated. METHODS:We designed this study to com...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1017/S0265021506002055
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Adding various opioids to the local anaesthetic solution administrated intrathecally improves the analgesic potency of spinal analgesia. The purpose of this study was to evaluate the efficacy and safety of intrathecal fentanyl 10 microg added to 15 mg hyperbaric ropivacaine in patients undergoi...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1017/s0265021505000785
更新日期：2005-06-01 00:00:00
abstract：:Anaesthetic agents for day-case surgery ideally should have a short duration of action. This study was designed to compare the efficacy and safety of mivacurium and vecuronium for healthy adults undergoing dental day-case surgery. Thirty fit healthy adult patients (ASA I or II) randomly received either mivacurium 0.15...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1046/j.1365-2346.1994.00207.x
更新日期：1997-11-01 00:00:00
abstract：:Prolongation of the QT interval may produce potentially hazardous dysrhythmias. The effects on the QT interval of midazolam followed by administration of either vecuronium or atracurium have been investigated. Thirty patients, ASA I or II, without cardiovascular problems, electrolyte abnormalities or receiving any med...
journal_title：European journal of anaesthesiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The effects of bicarbonated Ringer's solution were evaluated and compared with those of acetated Ringer's, lactated Ringer's and Ringer's solutions in partially hepatectomized rabbits. METHOD:Animals were randomly divided into six groups (n = 6 in each group): a sham-operated group, an operate...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章
doi：10.1017/s0265021505001043
更新日期：2005-08-01 00:00:00
abstract：:The majority of contemporary gas delivery modules, on anaesthetic workstations, are equipped with oxygen-nitrous oxide proportioning systems which should prevent the delivery of hypoxic gas mixtures. We investigated five modules, of two different types, using fresh gas flows ranging from 50 mL min-1 to 20 L min-1 with...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章
doi：10.1097/00003643-199601000-00013
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:Hypoventilation is a major cause of morbidity and mortality in patients having procedures under sedation. Few clinical strategies have been evaluated to reduce intraoperative hypoventilation during surgical procedures under deep sedation. OBJECTIVE:The primary objective of this investigation was to examine ...
journal_title：European journal of anaesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1097/EJA.0000000000000025
更新日期：2014-12-01 00:00:00
