Abstract:
OBJECTIVE:To assess the long-term effect of dietary advice on diet and mortality after a randomised trial of men with a recent history of myocardial infarction. DESIGN:Questionnaire survey and mortality follow-up after a trial of dietary advice. SETTING:Twenty-one hospitals in south Wales and south-west England. SUBJECTS:Former participants in the Diet and Reinfarction Trial. MAIN OUTCOME MEASURES:Current fish intake and cereal fibre intake. All-cause mortality, stroke mortality and coronary mortality. RESULTS:By February 2000, after 21147 person years of follow-up, 1083 (53%) of the men had died. Completed questionnaires were obtained from 879 (85%) of the 1030 men alive at the beginning of 1999. Relative increases in fish and fibre intake were still present at 10 y but were much smaller. The early reduction in all-cause mortality observed in those given fish advice (unadjusted hazard 0.70 (95% CI 0.54, 0.92)) was followed by an increased risk over the next 3 y (unadjusted hazard 1.31 (95% CI 1.01, 1.70). Fat and fibre advice had no clear effect on coronary or all-cause mortality. The risk of stroke death was increased in the fat advice group-the overall unadjusted hazard was 2.03 (95% CI 1.14, 3.63). CONCLUSIONS:In this follow-up of a trial of intensive dietary advice following myocardial infarction we did not observe any substantial long-term survival benefit. Further trials of fish and fibre advice are feasible and necessary to clarify the role of these foods in coronary disease.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Ness AR,Hughes J,Elwood PC,Whitley E,Smith GD,Burr MLdoi
10.1038/sj.ejcn.1601342subject
Has Abstractpub_date
2002-06-01 00:00:00pages
512-8issue
6eissn
0954-3007issn
1476-5640journal_volume
56pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND/OBJECTIVES:A high prevalence of Type 2 diabetes exists in Saudi Arabia. Epidemiological evidence suggests that low glycaemic index (GI) diets reduce diabetes risk. Yet, little is known about the GI of traditional Saudi Arabian staples such as Hassawi rice (HR). HR was evaluated in terms of its GI and insulin...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2011.4
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:We set up a baseline data on urinary iodine excretion from a nationwide representative sample of rural schoolchildren before instituting iodine supplementation. DESIGN:Stratified multistage cluster sampling in three different strata: lowlands, foothills and mountainous areas. Early morning urine samples were...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600562
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Observational studies have suggested low serum levels of vitamin B12 or folate to be risk factors of depression and anxiety. However, these results may be biased by confounding and reverse causation. Mendelian randomization studies are not subject to these limitations. The aim was to examine the a...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
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更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the role of the C677T-MTHFR (methylenetetrahydrofolate reductase)-polymorphism (CC, CT and TT) for vascular complications in liver transplant recipients. DESIGN:Retrospective study. SETTING:Hepatology-Transplantation-Unit, Johann Wolfgang Goethe-University, Frankfurt am...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602699
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To determine the effect of iron supplementation on iron status and endurance capacity. DESIGN:Randomized, double-blind iron supplementation. SETTING:University of Missouri-Columbia and surrounding community. SUBJECTS:Twenty iron-deficient (serum ferritin, sFer<16 microg/l; serum transferrin receptor, sTfR>...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602479
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Several studies have found an inverse association between fish consumption and risk of dementia. The objective of this study was to describe the characteristics of older fish consumers, in order to identify potential confounders in this relationship. DESIGN:Cross-sectional analysis of the baseline data of a ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/sj.ejcn.1602145
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To explore whether mothers' lifetime experiences with their own weight status and related cognitive and affective factors influence child feeding behavior. SUBJECTS/METHODS:Overweight mothers (N = 221) of 4-5 year olds recalled their weight at four time points, and were grouped into weight histor...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-017-0071-0
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To investigate the separate and combined effect of wine-drinking and other alcoholic beverages on esophageal cancer, in a high wine-consuming population. DESIGN:Combined analysis of two hospital-based case-control studies. SETTING:Major teaching and general hospitals in the greater Milan area and in the pro...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601113
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Disruptions in redox balance lead to oxidative stress, a promoter of morbidity in critical illness. This study aimed to: (1) characterize the plasma and alveolar thiol/disulfide redox pools, (2) examine their associations with alveolar macrophage phagocytosis, and (3) determine the effect of high ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41430-017-0047-0
更新日期:2018-05-01 00:00:00
abstract::The objective of this study was to measure lutein and zeaxanthin plasma levels after oral lutein administration in preterm infants. Lutein was given orally in a single dose of 0.5 mg/kg to 10 preterm infants at a mean age of 52 h of life. Plasma lutein and zeaxanthin were measured before and 6, 24, 48, and 120 h after...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:10.1038/ejcn.2010.62
更新日期:2010-07-01 00:00:00
abstract::We previously detected that ~50% of kidney transplant patients (KTPs) present sarcopenia using the first European Working Group on Sarcopenia in Older People (EWGSOP1) consensus. Our aim was to evaluate the agreement between the sarcopenia diagnosis using EWGSOP1 and the new consensus (EWGSOP2) in KTPs. A cross-sectio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-019-0535-5
更新日期:2020-07-01 00:00:00
abstract::Nutrient intake was assessed for 15 long-stay elderly patients by 7-d weighed inventory. Analysis revealed neither significant day-to-day nor weekday/weekend variations for any studied nutrient except fibre. It would appear that acceptable indications of customary intake in this population can be achieved by measureme...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1988-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Excessive consumption of sugar-sweetened beverages (SSBs) increases risk of obesity. Similar data are lacking in Chinese populations with rapid nutritional transition. We aimed to examine the association between SSB intake, lifestyle factors and obesity in Hong Kong Chinese. SUBJECTS/METHODS:This...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.181
更新日期:2010-12-01 00:00:00
abstract::Assessing diet through dietary patterns has become popular in diet-disease investigations due to the appealing simplicity of expressing several dietary exposures through one variable. Current evidence suggests that there may exist a priori and a posteriori dietary patterns that are consistently associated with reduced...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
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更新日期:2018-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:There is a lack of detailed data on fish consumption in European children and adolescents. We therefore investigated fish consumption patterns, portion sizes and estimated intakes of long-chain n-3 polyunsaturated fatty acids (PUFA; eicosapentaenoic acid, docosahexaenoic acid). SUBJECTS/METHODS:F...
journal_title:European journal of clinical nutrition
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doi:10.1038/ejcn.2009.40
更新日期:2009-09-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-00802-4
更新日期:2020-11-16 00:00:00
abstract:OBJECTIVE:To assess vitamin D status in women and their children aged 4-5 years in Northern Jordan during summer. DESIGN:A cross-sectional study in which 93 mother-child dyads volunteered through local community centers between June and July 2007. Anthropometric measurements were performed and information on socioecon...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.99
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between the common cold and vitamin C supplementation. DESIGN:A double-blind, 5-year randomized controlled trial. SETTING:A village in Akita prefecture, one of the regions in Japan with the highest mortality from gastric cancer. SUBJECTS:Participants in annual screening prog...
journal_title:European journal of clinical nutrition
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更新日期:2006-01-01 00:00:00
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更新日期:2018-01-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
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abstract:BACKGROUND:Studies have shown that depression relates to biomarkers of both short- and long-term polyunsaturated fatty acid (PUFA) intake. However, it is not known which of these two biomarkers has the closest relationship to depression. OBJECTIVE:To examine the relationship of depression with both adipose tissue and ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602413
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:In view of the ongoing debate on "chronic malnutrition" and the concept of "stunting" as "a better measure than underweight of the cumulative effects of undernutrition and infection (WHO)", we translate, briefly comment and re-publish three seminal historic papers on catch-up growth following re-feeding afte...
journal_title:European journal of clinical nutrition
pub_type: 历史文章,杂志文章,评审
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更新日期:2018-12-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601387
更新日期:2002-08-01 00:00:00
abstract::Evidence is accumulating that obesity risks become established early in life. The goal of this systematic review is to assess whether there is evidence that rapid postnatal growth holds different implications for childhood obesity risks for children who experienced different patterns of prenatal growth. We conducted s...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
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更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:There is experimental evidence that riboflavin (vitamin B2) supplementation reduces oxidative damage and cerebral oedema following acute stroke. OBJECTIVE:To measure riboflavin levels in acute stroke before and after supplementation with this vitamin. DESIGN:Ninety-six acute ischaemic stroke patients had t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602666
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The term 'beer belly' expresses the common belief that beer consumption is a major determinant of waist circumference (WC). We studied the gender-specific associations between beer consumption and WC (partially in relation to body weight and hip circumference (HC) change). PARTICIPANTS/METHODS:Wi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章
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更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:[corrected] To study the existence of a graded relationship between the nutrient content of the diet and some measures of social position. DESIGN AND SETTING:The graded relationship hypothesis was verified by secondary analysis performed on two different nutrition surveys: the Quebec Nutrition Survey (QNS) a...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601165
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Previous research has shown, in predominantly European populations, that dietary patterns are evident early in life. However, little is known about early-life dietary patterns in Australian children. We aimed to describe dietary patterns of Australian toddlers and their associations with socio-dem...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To compare the validity of skinfold anthropometry (SFA) and bioelectrical impedance (BIA) for the measurement of body composition in patients with chronic renal failure (CRF). DESIGN:We compared measurement of % total body fat (%TBF) and fat-free mass (FFM) by BIA and SFA, with dual energy X-ray absorptiomet...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00