A gene expression analysis in rat kidney following high and low salt intake.

abstract：BACKGROUND:The usefulness of the hypertensive retinopathy classification by Keith-Wagener-Barker (KWB) in clinical practice remains controversial. The simplified Mitchell-Wong grading, combining the two initial KWB' grades in one stage, is proposed as an alternative method; both systems are poorly validated regarding t...

journal_title：Journal of hypertension

authors： Aissopou EK,Papathanassiou M,Nasothimiou EG,Konstantonis GD,Tentolouris N,Theodossiadis PG,Papaioannou TG,Sfikakis PP,Protogerou AD

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Various studies have suggested that a delay in the time between diagnosing hypertension and its correct control (D-C, diagnostic-control time) is linked to a worse prognosis. The aim of this study was to examine the relationship between D-C time and all-cause mortality, or the incidence of cardiovascular even...

journal_title：Journal of hypertension

authors： Martín-Fernández M,Vinyoles E,Real J,Soldevila N,Muñoz MÁ,Del-Val JL,Verdú JM,Domingo M,Mundet X

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Daily exposure to air-jet stress (AJS) causes sustained elevations of blood pressure in borderline hypertensive rats (BHR). It is known that the renin-angiotensin system is activated during episodes of behavioral stress, and the purpose of this study was to assess the involvement of renin-angiotensin system i...

journal_title：Journal of hypertension

authors： Coste SC,Qi Y,Brooks VL,McCarron DA,Hatton DC

更新日期：1995-12-01 00:00:00

abstract：:Experimental models of genetic hypertension are used to develop paradigms to study human essential hypertension while removing some of the complexity inherent in the study of human subjects. Since 1991 several quantitative trait loci responsible for blood pressure regulation have been identified in various rat crosses...

journal_title：Journal of hypertension

authors： Dominiczak AF,Clark JS,Jeffs B,Anderson NH,Negrin CD,Lee WK,Brosnan MJ

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:We have previously described anatomical changes in pulmonary blood flow distribution in chronic hypoxic rats, associated with pulmonary arterial hypertension (PAH). METHOD:In this study, we utilized synchrotron radiation microangiography to compare these changes in pulmonary blood flow with a PAH-model indu...

journal_title：Journal of hypertension

authors： Schwenke DO,Pearson JT,Shimochi A,Kangawa K,Tsuchimochi H,Umetani K,Shirai M,Cragg PA

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the prognostic significance of cardiovascular risk factors including 24-h ambulatory blood pressure level and rhythm for all-cause mortality in type 2 diabetic patients. METHODS:In a prospective observational study, 104 patients with type 2 diabetes were followed: 51 patients with diabetic nephro...

journal_title：Journal of hypertension

authors： Astrup AS,Nielsen FS,Rossing P,Ali S,Kastrup J,Smidt UM,Parving HH

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:Calcium blockade has been reported to inhibit the contraction of the vascular smooth muscle and the liberation of vasoactive substances by endothelial cells. We tested the effects of calcium blockade on the mechanical properties of the carotid artery in normotensive Wistar-Kyoto (WKY) rats and spontaneously ...

journal_title：Journal of hypertension

authors： Lévy BI,el Fertak L,Pieddeloup C,Barouki F,Safar ME

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:Cardiovascular reactivity to mental stress has been used as a tool to predict short-term hypertension risk in adults but the impact of cardiovascular reactivity in childhood on hypertension in adulthood is unknown. Using the 1970 British Cohort study, we examined the association between pulse rate reactivity in...

journal_title：Journal of hypertension

authors： Hamer M,Kivimäki M,Batty GD

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE(S):To study the changes in macrophage inducible nitric oxide synthase (iNOS) activity, plasma levels of nitrite, lipid peroxidation (LPO) and melatonin in human essential hypertension before and 6 months after 4 mg/day lacidipine treatment. DESIGN:The study was carried out in a total of 25 subjects--11 healt...

journal_title：Journal of hypertension

authors： Escames G,Khaldy H,León J,González L,Acuña-Castroviejo D

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Several cytokines and adhesion molecules released from endothelium play an important role in inflammation, immune responses, and probably atherogenesis. OBJECTIVE:To determine whether the transcription factor nuclear factor-kappaB mediated expression of these genes involved in the inflammatory response of e...

journal_title：Journal of hypertension

authors： Tomita N,Morishita R,Tomita S,Yamamoto K,Aoki M,Matsushita H,Hayashi S,Higaki J,Ogihara T

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:Phenotypic transformation of adventitial fibroblasts is important in the pathogenesis of hypertension. This study was designed to determine whether fibronectin type III domain containing 5 (FNDC5) alleviates the phenotypic transformation of adventitial fibroblasts in hypertension and the underlying mechanisms...

journal_title：Journal of hypertension

authors： Ling L,Chen D,Tong Y,Zang YH,Ren XS,Zhou H,Qi XH,Chen Q,Li YH,Kang YM,Zhu GQ

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Little data is available concerning the prognostic implications of renal function abnormalities, their evolution over time and the effects of nifedipine on such abnormalities in patients with stable angina pectoris. METHODS:The previously published ACTION trial compared long-acting nifedipine GITS 60 mg onc...

journal_title：Journal of hypertension

authors： Ruilope LM,Kirwan BA,de Brouwer S,Danchin N,Fox KA,Wagener G,Segura J,Poole-Wilson PA,Lubsen J,ACTION investigators.

更新日期：2007-08-01 00:00:00

abstract：:To evaluate factors influencing hemodynamic responses to psychological and physical stress, 117 normotensive college students were studied. The standardized tests included arithmetic, Stroop word-color, mirror draw, isometric handgrip and cold pressor challenges. The responses of blood pressure and pulse during the te...

journal_title：Journal of hypertension

authors： McAdoo WG,Weinberger MH,Miller JZ,Fineberg NS,Grim CE

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To assess the dilatory effectiveness of nitric oxide donors in resistance arteries of patients with arterial hypertension in comparison with that in those of normotensive controls. BACKGROUND:Endothelium-dependent vasodilation has been demonstrated to be impaired in arterial hypertension. Besides disturbance...

journal_title：Journal of hypertension

authors： Preik M,Kelm M,Feelisch M,Strauer BE

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVES:It is well known that among hypertensive patients, an increased left ventricular mass (LVM) is a powerful predictor of cardiovascular morbidity and mortality. However, the mechanisms underlying LVM in hypertension are not completely understood, as the absolute value of blood pressure and other risk factors a...

journal_title：Journal of hypertension

authors： Menni C,Boffi L,Cesana F,Viviani Anselmi C,Nava S,Bertola F,Blasio AM,Roncarati R,Trimarco V,Marino M,Trimarco B,Grassi G,Giannattasio C,Mancia G

更新日期：2012-11-01 00:00:00

abstract：:We have studied the effect of parathyroidectomy on the systolic blood pressure, cardiovascular reactivity and the contractile response of isolated aorta to norepinephrine in the genetically hypertensive Lyon rat strain (LH), parathyroidectomized hypertensive Lyon rats (LH-PTX) and parathyroidectomized hypertensive Lyo...

journal_title：Journal of hypertension

authors： Pernot F,Schleiffer R,Vincent M,Sassard J,Gairard A

更新日期：1990-12-01 00:00:00

abstract：:Haemorheological characteristics were measured in a group of 52 patients with essential arterial hypertension (HT), and were compared with those of a group of normotensive subjects. The relationships between the arterial blood pressure (BP), the echocardiographic indices of left ventricular hypertrophy (LVH), and the ...

journal_title：Journal of hypertension

authors： Zannad F,Voisin P,Brunotte F,Bruntz JF,Stoltz JF,Gilgenkrantz JM

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVE:To determine if the contribution of the sympathetic nervous system to blood pressure could be evidenced by low-frequency oscillations of systolic blood pressure (LF(SBP)), reflecting vascular sympathetic modulation, or by the decrease in blood pressure after autonomic blockade. DESIGN:We studied multiple sys...

journal_title：Journal of hypertension

authors： Diedrich A,Jordan J,Tank J,Shannon JR,Robertson R,Luft FC,Robertson D,Biaggioni I

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:In a previous study, we found that neonatal sympathectomy prevented the development of angiotensin II (ANG II)-induced hypertension but not the development of structural changes in small mesenteric arteries. OBJECTIVES:To investigate further the dissociation between hypertension and structural vascular chan...

journal_title：Journal of hypertension

authors： Simon G,Csiky B

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Patients with essential hypertension exhibit several red blood cell (RBC) ion transport abnormalities, insulin resistance (IR) and increased risk of developing type 2 diabetes. The aims of this study were to assess RBC ion transport activities under basal conditions and to test the in vivo effect of acute hyp...

journal_title：Journal of hypertension

authors： Suchánková G,Vlasáková Z,Zicha J,Vokurková M,Dobesová Z,Pelikánová T

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:Rapid growth velocity in early life may be a risk factor for obesity, elevated blood pressure, and adverse metabolic markers in childhood, but results are not consistent. We analysed the association between peak growth velocity during the first 2 years of life and blood pressure, fasting glucose and insulin ...

journal_title：Journal of hypertension

authors： Thiering E,Brüske I,Kratzsch J,Hoffmann B,Herbarth O,von Berg A,Schaaf B,Wichmann HE,Heinrich J,LISAplus Study Group.

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:Renal denervation (RDN) can reduce sympathetic activity and blood pressure (BP) in patients with hypertension. The effects on resting and ambulatory heart rate (HR), also regulated by the sympathetic nervous system, are not established. METHODS:Herein, we report 12-month outcomes from the Global SYMPLICITY ...

journal_title：Journal of hypertension

authors： Böhm M,Ukena C,Ewen S,Linz D,Zivanovic I,Hoppe U,Narkiewicz K,Ruilope L,Schlaich M,Negoita M,Schmieder R,Williams B,Zeymer U,Zirlik A,Mancia G,Mahfoud F,Global SYMPLICITY Registry Investigators.

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To verify the benefit of renin-angiotensin system blockade in hypertension, the effects of 24 weeks' losartan and ramipril treatment, both alone and in combination, on urinary albumin excretion (UAE) and circulating transforming growth factor beta1 (TGF beta1) have been evaluated in hypertensive subjects with...

journal_title：Journal of hypertension

authors： Scaglione R,Argano C,Corrao S,Di Chiara T,Licata A,Licata G

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to identify, describe, and evaluate the available cardiovascular disease risk prediction models developed or validated in the hypertensive population. METHODS:MEDLINE and the Web of Science were searched from database inception to March 2019, and all reference lists of included arti...

journal_title：Journal of hypertension

authors： Cai R,Wu X,Li C,Chao J

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Blood pressure (BP) control is the most established practice for preventing the progression of chronic kidney disease (CKD). We examined the BP control and nocturnal dipping pattern changes in hypertensive patients with CKD and their effects on target organ damages. METHODS:We recruited 378 hypertensive CKD ...

journal_title：Journal of hypertension

authors： Cha RH,Lee H,Lee JP,Kang E,Song YR,Kim YS,Kim SG

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Recently, an apparently novel, specific endothelin-1 inactivating metalloendopeptidase (ET-1 peptidase) has been isolated from the rat kidney. In this study we attempted to determine whether the same or a similar peptidase is present in the human kidney, and whether the enzyme is excreted into the urine. The ...

journal_title：Journal of hypertension

authors： Janas J,Sitkiewicz D,Januszewicz A,Szczesniak C,Grenda R,Janas RM

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:Excess oxidative stress is one of the major metabolic abnormalities on vascular walls in hypertension and atherosclerosis. In order to further elucidate the endothelial function under oxidative stress, the effect of hydrogen peroxide (H2O2) on expression of two novel endothelium-derived vasorelaxing peptides,...

journal_title：Journal of hypertension

authors： Chun TH,Itoh H,Saito T,Yamahara K,Doi K,Mori Y,Ogawa Y,Yamashita J,Tanaka T,Inoue M,Masatsugu K,Sawada N,Fukunaga Y,Nakao K

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) remodeling and aortic stiffness have independent predictive value for all causes and cardiovascular mortality. Because elastic properties of the arterial wall vary along the aortic pathway, we hypothesized that local and regional aortic stiffness could differently impact on LV remodelin...

journal_title：Journal of hypertension

authors： Quinaglia T,Bensalah MZ,Bollache E,Kachenoura N,Soulat G,Boutouyrie P,Laurent S,Mousseaux E

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To investigate gender-dependent difference in the free cytosolic calcium concentration ([Ca2+ ]i ) response to angiotensin II (Ang II) in vascular smooth muscle cells (VSMC) isolated from spontaneously hypertensive rats (SHR). To further evaluate this gender-dependent difference by studying the role of thapsi...

journal_title：Journal of hypertension

authors： Loukotová J,Kunes J,Zicha J

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Hypertension control is often inadequate in HIV patients. In a contemporary, nationwide cohort of Italian HIV-infected adults, we assessed time trends in hypertension prevalence, awareness, treatment, and control. We also evaluated predictors of cardiovascular events and of new-onset hypertension. METHODS:M...

journal_title：Journal of hypertension

authors： De Socio GV,Ricci E,Maggi P,Parruti G,Celesia BM,Orofino G,Madeddu G,Martinelli C,Menzaghi B,Taramasso L,Bonfanti P,Pucci G,Schillaci G,CISAI study group.

更新日期：2017-02-01 00:00:00