Abstract:
:Oesophageal atresia (OA) is often associated with anomalies of other systems. The genetic contribution to the formation of the VACTERL association is not clear. The objective of this study was to evaluate the incidence of associated anomalies in two different racial populations. The associated anomalies in neonates with OA managed in an Asian and a European paediatric surgical centre from 1982 to 1998 were reviewed. Non-Asian and non-European patients were excluded from the respective centres. The incidence of anomalies was compared using Fisher's exact test, taking #E5/E5# below 0.05 as statistically significant. Forty-eight consecutive Asian (25 boys and 23 girls) and 34 consecutive European patients (20 boys and 14 girls) were included in the analysis. The percentage of patients with at least one associated anomaly was 50% and 74% in the Asian and European populations, respectively, which was significantly different (#E5/E5#=0. 04). There was no statistically significant difference in the incidence of associated cardiovascular (29% vs 39%), anorectal (11% vs 18%), and musculoskeletal (16% vs 22%) anomalies, duodenal atresia (4% vs 3%), or Down's syndrome (3% vs 6%) between the two populations. However, the European patients had a significantly higher incidence of urogenital (UG) anomalies (26% vs 4%, #E5/E5#=0.006), the most common being agenesis (n=4) and dysplasia (n=3) of one or both kidneys. Hereditary factors may influence the incidence of associated anomalies in children with OA, particularly of the UG system. However, environmental factors cannot be excluded.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
van Heurn LW,Cheng W,de Vries B,Saing H,Jansen NJ,Kootstra G,Tam PKdoi
10.1007/s003830100692subject
Has Abstractpub_date
2002-05-01 00:00:00pages
241-3issue
4eissn
0179-0358issn
1437-9813journal_volume
18pub_type
杂志文章abstract::Africa faces a triple burden of disease; HIV, tuberculosis and malaria. Despite this, its population is expected to double over the next 45 years. There is a dire shortage of medical specialists and many countries lack suitably qualified doctors to train medical specialists. Videoconferencing offers the opportunity to...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2085-5
更新日期:2008-02-01 00:00:00
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journal_title:Pediatric surgery international
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journal_title:Pediatric surgery international
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doi:10.1007/s00383-012-3113-7
更新日期:2012-10-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0888-y
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journal_title:Pediatric surgery international
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doi:10.1007/s003830000515
更新日期:2001-07-01 00:00:00
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journal_title:Pediatric surgery international
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doi:10.1007/s003830050408
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00183739
更新日期:1996-03-01 00:00:00
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journal_title:Pediatric surgery international
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journal_title:Pediatric surgery international
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doi:10.1007/s00383-020-04851-5
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1562-y
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-010-2577-6
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journal_title:Pediatric surgery international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00383-019-04440-1
更新日期:2019-04-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-009-2333-y
更新日期:2009-03-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00174584
更新日期:1996-12-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 已发布勘误
doi:10.1007/s00383-020-04624-0
更新日期:2020-04-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1331-3
更新日期:2005-02-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章,多中心研究
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更新日期:2018-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00383-017-4072-9
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-1957-z
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doi:10.1007/s00383-005-1617-0
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journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
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更新日期:2008-10-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1534-2
更新日期:2005-09-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0931-z
更新日期:2003-06-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3833-6
更新日期:2016-03-01 00:00:00
abstract::The presentation of congenital diaphragmatic hernia (CDH) at birth may fall outside the typical features (cyanosis, tachypnea and respiratory failure), manifesting, instead, also with others pictures that make the diagnosis difficult or even impossible. We report a case of CDH presenting as a pneumothorax and a perfor...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-007-2000-0
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:The need for clinically applicable skin substitutes continues to be a matter of fact. Hypothetically, a laboratory grown autologous skin analog with near normal architecture might be a suitable approach to yield both satisfactory functional and cosmetic long-term results. In this study, we explored the use of h...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3808-7
更新日期:2016-01-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-017-4067-6
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION:We assessed the impact of intestinal transplantation on Japanese pediatric patients with intestinal failure with data from the Japanese intestinal transplant registry. METHODS:Standardized forms were sent to all known intestinal transplantation programs, requesting information on transplants performed bet...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3392-7
更新日期:2013-10-01 00:00:00