Prolactin receptor in human endometriotic tissues.

Abstract:

BACKGROUND:Augmented serum prolactin (PRL) levels have been implicated as a cause for infertility in patients with endometriosis. However, it has not been established whether this lactogenic hormone or its receptor (PRLR) have specific effects on the development of human endometriosis. In the present study we assessed PRLR expression in human endometriotic and normal tissue. METHODS:Fourteen patients with laparoscopically proven endometriosis were recruited and the negative or positive expression of the PRLR in normal endometrial and endometriotic tissues obtained during the mid-late proliferative phase of the menstrual cycle was evaluated by RT-PCR. Evaluation of serum prolactin, and peritoneal fluid estradiol content were carried out by specific radioimmunoassays (RIA). RESULTS:In endometriotic tissue samples the corresponding 1048 bp PRLR transcript was negative in 12/14 of the samples (86%) and positive in two samples (14%). The opposite was seen in normal tissue, since PRLR expression was positive in 11/14 samples (79%) and negative in the remaining three samples (21%). There was an association between serum prolactin concentrations and PRLR expression in normal tissue but not in endometriotic tissue. CONCLUSIONS:The PRLR is expressed in normal endometrium, while cells of the endometriotic tissues did not express the PRLR, at least during the mid-late proliferative phase of the menstrual cycle. The absence of the PRLR in the endometriotic tissues could not be correlated with the serum prolactin levels. These results suggest the existence of differential regulation of PRLR expression between normal and endometriotic tissue.

authors

Martinez LB,Leyva MZ,Romero IC

doi

10.1034/j.1600-0412.2002.810102.x

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

5-10

issue

1

eissn

0001-6349

issn

1600-0412

journal_volume

81

pub_type

杂志文章
  • Fibrinogen and histidine-rich glycoprotein in early-onset preeclampsia.

    abstract:OBJECTIVE:To determine whether plasma levels of fibrinogen and the placental tissue distributions of fibrinogen and histidine-rich glycoprotein (HRG) differ between early- and late-onset preeclampsia. DESIGN:The study comprised 18 women with early-onset (gestational weeks 24-32) and 19 women with late-onset (gestation...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016340903295618

    authors: Kårehed K,Wikström AK,Olsson AK,Larsson A,Olovsson M,Akerud H

    更新日期:2010-01-01 00:00:00

  • The value of routine estradiol monitoring in assisted conception cycles.

    abstract:BACKGROUND:Traditional monitoring of an in vitro fertilization (IVF) treatment cycle includes regular estradiol levels and ultrasound scans in an attempt to reduce the risk of ovarian hyperstimulation syndrome (OHSS). The need for estradiol monitoring remains controversial. METHODS:We reviewed 538 consecutive cycles o...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.2002.810613.x

    authors: Thomas K,Searle T,Quinn A,Wood S,Lewis-Jones I,Kingsland C

    更新日期:2002-06-01 00:00:00

  • Preinductive cervical ripening with PgE2 gel in term pregnant women with ultrasonically diagnosed intra-uterine growth-retarded fetuses.

    abstract::Intra-uterine growth retardation (IUGR), often combined with other pregnancy-related complications, constitutes a rather common indication for labor induction. The objective of this prospective study was to evaluate a strict intracervical application of 0.5 mg PgE2 in gel for cervical ripening and labor induction. Eig...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349109007916

    authors: Almström H,Ekman G,Granström L

    更新日期:1991-01-01 00:00:00

  • Histopathological prognostic factors of adult granulosa cell tumors of the ovary.

    abstract:BACKGROUND:The prognostic factors of adult granulosa cell tumor (AGCT) have not been well defined. METHODS:In 27 AGCT patients, we examined clinical stage, microscopic patterns, mitotic index (MI), and lymph-vascular space invasion (LVSI) to determine whether these factors were related to disease-free survival (DFS) o...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.2001.801120.x

    authors: Fujimoto T,Sakuragi N,Okuyama K,Fujino T,Yamashita K,Yamashiro S,Shimizu M,Fujimoto S

    更新日期:2001-11-01 00:00:00

  • Osteoporosis--an update.

    abstract::Osteoporosis and subsequent fractures is a rapidly growing major health problem in many parts of the world. Even if prevalence and incidence are high in Europe, rate of increase is even higher in Asia. The majority of fractures occur in women underlining the importance of ovarian deficiency. Genetic factors and lifest...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:

    authors: Samsioe G

    更新日期:1997-03-01 00:00:00

  • Physical therapy for pregnancy-related low back and pelvic pain: a systematic review.

    abstract:BACKGROUND:A systematic review of prospective controlled clinical trials was performed to assess the effectiveness of physical therapy interventions for the prevention and treatment of pregnancy-related back and pelvic pain. Pregnancy-related low back and pelvic pain has an impact on daily life for many women. Preventi...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1034/j.1600-0412.2003.00125.x

    authors: Stuge B,Hilde G,Vøllestad N

    更新日期:2003-11-01 00:00:00

  • Endometrial destruction by hyperthermia--a possible treatment of menorrhagia. An experimental study.

    abstract:BACKGROUND:Treatment of menorrhagia by heat-destruction of the endometrium, intended to be an alternative to hysterectomy, was investigated in an experimental study. METHOD:A specially designed catheter (CavatermTM) with a silicone balloon containing a self-regulating containing heating element is inserted into the ut...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016349609033325

    authors: Friberg B,Persson BR,Willén R,Ahlgren M

    更新日期:1996-04-01 00:00:00

  • Increased tissue concentrations of arachidonic acid in umbilical artery and placenta in fetal growth retardation.

    abstract:OBJECTIVE:To compare the fatty acid phospholipid composition of the umbilical artery and the placenta in cases of fetal growth retardation (FGR) and of normal growth, as well as in symmetric and asymmetric FGR. DESIGN:Case-control study. SETTING:University hospital. POPULATION:Thirty-nine FGR cases (12 asymmetric, 2...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.2001.080009807.x

    authors: Matorras R,López De Larrucea A,Sanjurjo P,Ignacio Ruiz J,Echevarría Y,Nieto A,Perteagudo L,Aldamiz-Echevarria JL

    更新日期:2001-09-01 00:00:00

  • Ultrasonography versus urography as preoperative investigation prior to hysterectomy.

    abstract::Ultrasonography (US) has been compared with urography (IVU) as a preoperative investigation prior to hysterectomy in 62 patients. In 38 patients the urinary tract was deemed normal by both US and IVU. US and IVU coincided in varying degrees of hydronephrosis in 8 patients and disagreed in one. Of 5 double ureters, US ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348909021018

    authors: Aslaksen A,Göthlin JH,Geitung JT,Anker C

    更新日期:1989-01-01 00:00:00

  • Maternal and neonatal outcomes of large for gestational age pregnancies.

    abstract:OBJECTIVE:To compare maternal and neonatal outcomes of term large for gestational age (LGA) pregnancies and adequate for gestational age (AGA) pregnancies. DESIGN:Retrospective analysis. SETTING:Large university research medical center. POPULATION:All term singleton LGA (birthweight ≥ 90th percentile) and AGA pregna...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2012.01412.x

    authors: Weissmann-Brenner A,Simchen MJ,Zilberberg E,Kalter A,Weisz B,Achiron R,Dulitzky M

    更新日期:2012-07-01 00:00:00

  • Classification of cesarean sections among immigrants in Belgium.

    abstract:OBJECTIVE:To provide insight into the differential effect of immigration on cesarean section (CS) rates, using the Robson classification. DESIGN:A population-based study using birth certificates from the birth registry of 2009. SETTING:All births in two of the three Belgian regions excluding Flanders. POPULATION:37 ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.12003

    authors: Minsart AF,De Spiegelaere M,Englert Y,Buekens P

    更新日期:2013-02-01 00:00:00

  • Bipolar cautery for laparoscopic sterilization.

    abstract::Laparoscopic sterilization with a bipolar electrode was performed in 62 patients. The sterilization failed in one patient and was questionable in another. The effectiveness was assessed by hysterosalpingography (HSG) in 51 patients. No complications due to laparoscopy occurred. The method is considered to be advantage...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347809155898

    authors: Gregersen E,Kjer JJ

    更新日期:1978-01-01 00:00:00

  • Total intra-uterine volume and symphysis fundus height. Is there a relation?

    abstract::The concordance between measurements of total intra-uterine volume (parallel planimetric area method) and symphysis fundus height and the efficacy of these measurements in predicting birthweight by centile range was prospectively investigated in a blind study of 81 measurement sets in 74 women in the third trimester o...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348709103650

    authors: Geirsson RT,Agustsson P

    更新日期:1987-01-01 00:00:00

  • Management of postmenopausal women with vaginal bleeding when the endometrium can not be visualized.

    abstract:OBJECTIVE:To determine the risk of endometrial cancer when endometrial thickness is not visualized using ultrasonography. DESIGN:Cross-sectional study. SETTING:Gynecological oncology center in the United Kingdom. POPULATION:All postmenopausal women referred with vaginal bleeding. METHODS:All women were investigated...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2012.01407.x

    authors: Burbos N,Musonda P,Crocker SG,Morris EP,Nieto JJ,Duncan TJ

    更新日期:2012-06-01 00:00:00

  • Factors associated with pregnancy termination in Ukrainian women.

    abstract:OBJECTIVES:To study differences in social and demographic characteristics between women undergoing an induced abortion and antenatal care attendants in the Ukraine. DESIGN:Hospital-based unmatched case control study. METHODS:From a survey including 1,694 women of fertile age, who attended five women's clinics in the ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Mogilevkina I,Hellberg D,Nordstrom ML,Odlind V

    更新日期:2000-12-01 00:00:00

  • Good perinatal outcome in selective vaginal breech delivery at term.

    abstract:BACKGROUND AND AIM:To compare perinatal outcome in groups of planned vaginal breech delivery, elective cesarean section with the fetus in breech presentation, and planned vaginal delivery with the fetus in cephalic presentation in a university hospital with a tradition of managing breech deliveries by the vaginal route...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2005.00248.x

    authors: Uotila J,Tuimala R,Kirkinen P

    更新日期:2005-06-01 00:00:00

  • The prognostic value of the miR-200 family in ovarian cancer: a meta-analysis.

    abstract:INTRODUCTION:To assess the association between miR-200 family expression and overall survival/progression-free survival in women with ovarian cancer. MATERIAL AND METHODS:A systematic literature search, up to September 2015, in PubMed, EMBASE and Cochrane Library was performed to identify articles that assessed the as...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/aogs.12883

    authors: Shi C,Zhang Z

    更新日期:2016-05-01 00:00:00

  • Treatment of abscesses in the vulva. Conventional open treatment versus primary suture under antibiotic cover.

    abstract::Seventy patients were treated for a subcutaneous abscess in the vulva. In 35 consecutive patients the abscess was treated conventionally with deroofing of the abscess and wet dressings. In the other 35 consecutive patients the abscess was treated by incision, curettage and primary suture under antibiotic cover with a ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348609157385

    authors: Larsen T,Larsen PN,Christophersen S,Moesgaard F,Nielsen ML

    更新日期:1986-01-01 00:00:00

  • Premalignant and malignant uterine changes in immunosuppressed renal transplant recipients.

    abstract::29 female immunosuppressed renal transplant recipients were examined gynecologically. In 2 cases the epithelium of the portio was found to be dysplastic, while endometrial carcinoma was present in 1 patient. A review of the literature suggests that immunosuppressed patients are more likely to develop tumors than other...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347809154202

    authors: Husslein H,Breitenecker G,Tatra G

    更新日期:1978-01-01 00:00:00

  • Birth outcomes in pregnant women treated with low-molecular-weight heparin.

    abstract:BACKGROUND:Pregnancy and puerperium are associated with an increased risk of venous thromboembolism. Low-molecular-weight heparin is the anticoagulant of choice in pregnant women because, unlike warfarin, it does not cross the placenta. However, there are limited data on the risk of adverse birth outcomes following use...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Sørensen HT,Johnsen SP,Larsen H,Pedersen L,Nielsen GL,Møller M

    更新日期:2000-08-01 00:00:00

  • Factors influencing delivery method in breech presentation.

    abstract:BACKGROUND:To study factors influencing delivery method in breech presentation. METHODS:Population based cohort study from The Medical Birth Registry of Norway, comprising all singleton deliveries in Norway, 1967-1994, 1,592,064 deliveries of which 45,921 (2.9%) were in breech presentation. RESULTS:The proportion of ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Albrechtsen S,Rasmussen S,Dalaker K,Irgens LM

    更新日期:1998-04-01 00:00:00

  • Dietary and lifestyle interventions to limit weight gain during pregnancy for obese or overweight women: a systematic review.

    abstract:BACKGROUND:To assess the benefits and harm of dietary and lifestyle interventions during pregnancy to improve maternal and infant outcomes for pregnant women who are overweight or obese. METHODS:Randomized controlled trials comparing any form of dietary or lifestyle intervention during pregnancy for women who are over...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1080/00016340802061111

    authors: Dodd JM,Crowther CA,Robinson JS

    更新日期:2008-01-01 00:00:00

  • The plasma concentration of medroxyprogesterone acetate and ovarian function during treatment with medroxyprogesterone acetate in 5 and 10 mg doses.

    abstract::Peripheral plasma levels of medroxyprogesterone acetate (MPA) were determined by radioimmunoassay in 5 women after oral administration of 5 and 10 mg medroxyprogesterone acetate daily. Peak levels of MPA in plasma were recorded within 1 - 3 hours of taking the tablet, which indicates a rapid absorption from the gastro...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348409154654

    authors: Wikström A,Green B,Johansson ED

    更新日期:1984-01-01 00:00:00

  • The effect of physical training on bone mineral density in women with endometriosis treated with GnRH analogs: a pilot study.

    abstract:BACKGROUND:The effect of physical training on bone mineral density (BMD) in women with endometriosis treated with gonadotropin-releasing hormone (GnRH) analogs was studied. METHODS:Nineteen Caucasian premenopausal women aged 23-38 years were included in the study. The subjects were all treated with 21.6 mg goserelin d...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.0001-6349.2005.00558.x

    authors: Bergström I,Freyschuss B,Jacobsson H,Landgren BM

    更新日期:2005-04-01 00:00:00

  • Echographic features and perinatal outcomes in fetuses with congenital absence of ductus venosus.

    abstract:INTRODUCTION:The purpose of this study was to describe the echographic features and perinatal outcomes of fetuses with absence of ductus venosus. MATERIAL AND METHODS:Retrospective review of 10 cases with absence of ductus venosus diagnosed by prenatal ultrasonography between January 2014 and February 2016 at a single...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13176

    authors: Garcia-Delgado R,Garcia-Rodriguez R,Romero Requejo A,Armas Roca M,Obreros Zegarra L,Medina Castellano M,Garcia Hernandez JA

    更新日期:2017-10-01 00:00:00

  • Serum lipoprotein and apolipoprotein changes during treatment with a contraceptive vaginal ring containing levonorgestrel and estradiol.

    abstract::Contraceptive vaginal rings containing estradiol and levonorgestrel were used by 22 women during 219 cycles. The estrogenicity was low and the daily dose of levonorgestrel was about 290 micrograms. The triglyceride and cholesterol concentrations decreased in whole serum and, to varying degrees, in the different lipopr...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348209156600

    authors: Ahrén T,Lithell H,Victor A,Vessby B,Johansson ED

    更新日期:1982-01-01 00:00:00

  • Premature rupture of fetal membranes changes in collagen type.

    abstract::Collagen from the chorioamnion units from premature and term pregnancies was solubilized by limited pepsin digestion and subjected to SDS-PAG electrophoresis. Collagen types were quantitated by densitometry. It was found that collagen type III decreases and collagen type V tends to increase as gestational age advances...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: al-Zaid NS,Gumaa KA,Bou-Resli MN,Ibrahim ME

    更新日期:1988-01-01 00:00:00

  • Longitudinal study of the uterine body and cavity with three-dimensional ultrasonography in the puerperium.

    abstract:OBJECTIVE:To describe uterine involution in the puerperium with three-dimensional ultrasound. DESIGN:Prospective, longitudinal study. SETTING:Fetal medicine unit, department of obstetrics and gynecology, university referral hospital, Uppsala, Sweden. POPULATION:Fifty women with uncomplicated deliveries and puerperiu...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0412.2012.01418.x

    authors: Belachew J,Axelsson O,Mulic-Lutvica A,Eurenius K

    更新日期:2012-10-01 00:00:00

  • The value of oral micronized progesterone in the prevention of recurrent spontaneous preterm birth: a randomized controlled trial.

    abstract:INTRODUCTION:Progesterone is becoming universally accepted for preventing recurrent spontaneous preterm delivery. There is, however, poor consensus on the effective types and doses of progesterone to be used. Despite the encouraging available research, the role of oral micronized progesterone has not yet been thoroughl...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/aogs.13236

    authors: Ashoush S,El-Kady O,Al-Hawwary G,Othman A

    更新日期:2017-12-01 00:00:00

  • Therapeutic group psychoeducation and relaxation in treating fear of childbirth.

    abstract:BACKGROUND:The increase in the numbers of women fearing childbirth and requesting cesarean sections call for new forms of antenatal treatment. METHODS:Finnish nulliparous women experiencing severe fear of childbirth (experimental group, n = 102) attended 5 group sessions with a psychologist, once together with a midwi...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1080/00016340600756920

    authors: Saisto T,Toivanen R,Salmela-Aro K,Halmesmäki E

    更新日期:2006-01-01 00:00:00