Iron-catalyzed reaction products of alpha-tocopherol with 1-palmitoyl-2-linoleoyl-3-sn-phosphatidylcholine (13S)-hydroperoxide.

abstract：:We have investigated monomolecular fluid-like films of palmitoyl oleoylphosphatidyl lipids with choline, glycerol and serine head groups, respectively. Conventional Langmuir trough experiments have been evaluated towards a thermodynamic analysis applying a novel approach that was recently developed in this laboratory....

journal_title：Chemistry and physics of lipids

authors： Weis I,Welzel PB,Bähr G,Schwarz G

更新日期：2000-03-01 00:00:00

abstract：:The concentration of TL in Penaeus kerathurus muscle and cephalothorax was 1.03+/-0.04 (75.9+/-0.8% of which was PhL) and 2.36+/-0.07% (45.5+/-0.8% of which was PhL) of the wet tissue, respectively. The phosphatidylethanolamine represented 26.4+/-0.6% (85.6% diacyl- and 14.4% alkyl-acyl- or alkenyl-acyl-analogues) of ...

journal_title：Chemistry and physics of lipids

authors： Miniadis-Meimaroglou S,Kora L,Sinanoglou VJ

更新日期：2008-04-01 00:00:00

abstract：:To exploit the potential of Didodecyldimethylammonium bromide (D12DAB) as a core lipidic constituent, an attempt was made to fabricate and optimize cationic nanostructured lipid carriers (cNLCs) using a cost-effective microemulsification methodology. Designed composition was optimized by studying the effect of differe...

journal_title：Chemistry and physics of lipids

authors： Kanwar R,Kaur G,Mehta SK

更新日期：2016-03-01 00:00:00

abstract：:[4,4-2H2]-, [5,5-2H2)-, [6-2H]-, [7-2H]-, [8,8-2H2)-, [11,11-2H2]-, [14,14-2H2]- and [18,18,18-2H3]-cis,cis-octadeca-6,9-dienoic (isolinoleic) acid were synthesized by supplementing cultures of the protozoan Tetrahymena with the corresponding deuterated cis-octadeca-9-enoic (oleic) acids. The cultures were harvested, ...

journal_title：Chemistry and physics of lipids

authors： Baenziger JE,Smith IC,Hill RJ

更新日期：1990-04-01 00:00:00

abstract：:Platelet activating factor is one of the most potent inflammatory ether phospholipid mediators known and structurally modified analogues are of considerable interest as potential therapeutic preparations. Inspired by the proposed structure for a novel endogenous hydroxy-PAF analogue isolated recently from gingival cre...

journal_title：Chemistry and physics of lipids

authors： Karantonis HC,Pitsinos EN,Antonopoulou S,Couladouros EA,Demopoulos CA

更新日期：2005-12-01 00:00:00

abstract：:The X-ray crystal structure of 3 beta-benzoyloxy-6 alpha-chloro-5 alpha-cholest-7-ene (IV) was determined by the heavy atom method and refined to R = 0.063 (space group P21, a = 11.364, b = 11.089, c = 12.232, beta = 99.43 degrees, Z = 2). IV was previously shown to be an important intermediate in the acid-catalyzed i...

journal_title：Chemistry and physics of lipids

authors： Wilson DK,Wilson WK,Quiocho FA,Schroepfer GJ Jr

更新日期：1988-08-01 00:00:00

abstract：:The aggregative properties of highly pure GM3 ganglioside in aqueous solution have been studied by static and dynamic laser light scattering measurements and fluorescence spectroscopy experiments performed by the use of a GM3 derivative containing the pyrene group at the end of the fatty acid moiety. GM3 ganglioside s...

journal_title：Chemistry and physics of lipids

authors： Sonnino S,Cantu L,Acquotti D,Corti M,Tettamanti G

更新日期：1990-02-01 00:00:00

abstract：:N-Acyl tris(hydroxymethyl)aminomethanes (N-acyl tris, NATs) are structural analogs of ceramides, which were reported to induce apoptosis either by elevation of ceramide levels or by activation of pro-apoptotic effectors that are physiological targets of ceramide. In this study, we synthesized and characterized a homol...

journal_title：Chemistry and physics of lipids

authors： D S,Ravindar C,Swamy MJ

更新日期：2018-12-01 00:00:00

abstract：:In the last 30 years, ceramides have been found to mediate a myriad of biological processes. Ceramides have been recognized as bioactive molecules and their metabolizing enzymes are attractive targets in cancer therapy and other diseases. The molecular mechanism of action of cellular ceramides are still not fully esta...

journal_title：Chemistry and physics of lipids

authors： Canals D,Salamone S,Hannun YA

更新日期：2018-11-01 00:00:00

abstract：:Ceramide-1-phosphate (C1P) is an important signaling sphingolipid and a metabolite of ceramide. C1P contains an anionic phosphomonoester head group and has been shown to regulate physiological and pathophysiological processes such as cell proliferation, inflammation, apoptosis, phagocytosis, and macrophage chemotaxis....

journal_title：Chemistry and physics of lipids

authors： Shirey CM,Ward KE,Stahelin RV

更新日期：2016-10-01 00:00:00

abstract：:The extracorporeal procedure for the specific removal of lipoprotein (a) (Lp(a)) from human plasma--Lp(a) apheresis--was applied to the treatment of three patients with coronary artery disease documented by angiography. Their initial lipid levels were as follows: total cholesterol, 210-230 mg/dl; low-density lipoprote...

journal_title：Chemistry and physics of lipids

authors： Pokrovsky SN,Sussekov AV,Afanasieva OI,Adamova IY,Lyakishev AA,Kukharchuk VV

更新日期：1994-01-01 00:00:00

abstract：:The interaction of the amphoteric surfactant N-dodecyl-N,N-dimethylbetaine (C12-Bet) with phosphatidylcholine (PC) liposomes was investigated. Permeability alterations were detected as a change in 5(6)-carboxyfluorescein (CF) released from the interior of vesicles and bilayer solubilization as a decrease in the static...

journal_title：Chemistry and physics of lipids

authors： de la Maza A,Lopez O,Coderch L,Parra JL

更新日期：1998-07-01 00:00:00

abstract：:Human erythrocyte band 3 reconstituted into phospholipid vesicles has been used for studying the interaction of interdigitated lipid bilayer with an integral membrane protein. The interdigitated gel phase in DPPG/band 3 or DPPG/DMPC/band 3 systems was induced with polymyxin B (PMB) or Tris+. The phase transitions of t...

journal_title：Chemistry and physics of lipids

authors： Wang PY,Lu JZ,Chen JW,Hwang F

更新日期：1994-03-01 00:00:00

abstract：:The properties of cholesterol in bilayers of egg phosphatidylcholine (PC) were investigated directly by means of 2H-NMR of specifically-deuterated species (C3, C7, C26, C27). Quadrupole splittings were a measure of molecular ordering, and relaxation times T1 and T2e were indicators of rates of motion. The importance o...

journal_title：Chemistry and physics of lipids

authors： Taylor MG,Akiyama T,Saitô H,Smith IC

更新日期：1982-12-01 00:00:00

abstract：:Ionic properties of didodecanoylphosphatidylglycerol (C12PG), didodecanolyphosphatidyl-l'-propanol (C12PP), di-(12-methyl, 13-methyl)-pentadecanoylphosphatidylglycerols (C15PG) and dihexadecanoylphosphatidylglycerol (C16PG) have been studied at the air-water interface using titration experiments at constant ionic stre...

journal_title：Chemistry and physics of lipids

authors： Sacré MM,Tocanne JF

更新日期：1977-04-01 00:00:00

abstract：:The 13C- and 31P-NMR spectra and DSC thermograms of unsonicated dispersions consisting of phospholipids of varying methylation stages of the propanolamine head group were investigated. Methylation of the head group was accompanied by a corresponding reduction in the phase transition temperatures. In the liquid crystal...

journal_title：Chemistry and physics of lipids

authors： Gawrisch K,Arnold K,Rüger HJ,Kertscher P,Nuhn P

更新日期：1977-12-01 00:00:00

abstract：:The gel-like liquid phase transition of dimyristoylphosphatidylcholine (DMPC) large unilamellar vesicles prepared by reverse phase evaporation has been investigated in buffers containing ethanol by quasi-elastic light scattering (QLS) and vibrational (infrared and Raman) spectroscopy. With the QLS technique, the relat...

journal_title：Chemistry and physics of lipids

authors： Hantz E,Cao A,Taillandier E

更新日期：1988-12-01 00:00:00

abstract：:Nitration of unsaturated fatty acids is a (patho)physiologically important pathway of lipid modification induced by nitric oxide-derived species. We report herein on the unexpected chain rearrangement undergone by (13S,9Z,11E)-13-hydroxyoctadeca-9,11-dienoic acid (1), a linoleic acid metabolite, when exposed to nitrat...

journal_title：Chemistry and physics of lipids

authors： Manini P,Camera E,Picardo M,Napolitano A,d'Ischia M

更新日期：2008-01-01 00:00:00

abstract：:Inverted cubic and isotropic phases have been observed in phospholipid and glycolipid systems. These phases exhibit characteristic morphologies in freeze-fracture electron micrographs, isotropic 31P-NMR resonances and (in some cases) cubic X-ray diffraction patterns. It is proposed here that these phases may form from...

journal_title：Chemistry and physics of lipids

authors： Siegel DP

更新日期：1986-12-31 00:00:00

abstract：:As part of a program to prepare delta 8(14)-15-ketosterols that cannot readily be metabolized to cholesterol or side-chain oxygenated species, we have prepared 3 beta-hydroxy-7 alpha-fluoro-5 alpha-cholest-8(14)-en-15-one (VII) and the 9 alpha-hydroxy (IV), 9 alpha-fluoro (VI) and 7 alpha-fluoro (VIII) derivatives of ...

journal_title：Chemistry and physics of lipids

authors： Siddiqui AU,Swaminathan S,Pinkerton FD,Gerst N,Wilson WK,Choi H,Schroephfer GJ Jr

更新日期：1994-06-24 00:00:00

abstract：:Interactions of the peptides melittin and magainin with phospholipid vesicle membranes have been studied using fluorescence correlation spectroscopy. Molecular interactions of melittin and magainin with phospholipid membranes are performed in rhodamine-entrapped vesicles (REV) and in rhodamine-labelled phospholipid ve...

journal_title：Chemistry and physics of lipids

authors： Pramanik A,Thyberg P,Rigler R

更新日期：2000-01-01 00:00:00

abstract：:2-N-(Hexadecanoyl)-amino-4-nitrophenyl phosphorylcholine-hydroxide a compound resembling sphingomyelin is synthesized. It is cleaved by sphingomyelinase to the chromogenic N-acylaminonitrophenyl moiety. Phospholipase C preparations do not hydrolyze this compound. The starting material is 2-amino-4-nitrophenol which wh...

journal_title：Chemistry and physics of lipids

authors： Gal AE,Fash FJ

更新日期：1976-02-01 00:00:00

abstract：:The orientational order and rotational dynamics of 1-palmitoyl-2-[[2-[4-(6-phenyl-trans-1,3,5- hexatrienyl)phenyl]ethyl] carbon yl]-3-sn-phosphatidylcholine (DPH-PC) in dilinoleoylphosphatidylethanolamine (DLPE) and 1-palmitoyl-2-oleoylphosphatidylcholine (POPC) binary lipid mixtures were investigated. A previous stud...

journal_title：Chemistry and physics of lipids

authors： Cheng KH

更新日期：1989-10-01 00:00:00

abstract：:Apolipoprotein B-100 (apoB-100) is the major protein in low-density lipoprotein (LDL) and contains the ligand for binding LDL to its cell surface receptor. Lipoprotein [a] (Lp[a]) is a lipoprotein that consists of LDL and apolipoprotein [a] (apo[a]). The primary structure of apoB-100 has been determined by a combinati...

journal_title：Chemistry and physics of lipids

authors： Yang C,Gu ZW,Yang M,Gotto AM Jr

更新日期：1994-01-01 00:00:00

abstract：:The influence of the temperature on the adsorption of monomeric and micellar solutions of the anionic surfactant sodium dodecyl sulfate (SDS) on phosphatidylcholine (PC) liposomes was investigated using the fluorescent probe 2-(p-toluidinyl)-naphthalene-6-sodium sulfonate (TNS). The number of adsorbed molecules was qu...

journal_title：Chemistry and physics of lipids

authors： Cócera M,López O,Estelrich J,Parra JL,de la Maza A

更新日期：2003-06-01 00:00:00

abstract：:Lipids have a variety of physiological roles, ranging from structural and biophysical contributions to membrane functions to signaling contributions in normal and abnormal physiology. This review highlights some of the contributions made by Robert Bittman to our understanding of lipid assemblies through the production...

journal_title：Chemistry and physics of lipids

authors： Parrill AL

更新日期：2016-01-01 00:00:00

abstract：:The stereochemistry of fat digestion and absorption was studied by feeding a triacylglycerol analogue to rats with a thoracic duct cannula. The analogue, rac-1,2-dioleoyl-3-S-tetradecyl-3-thioglycerol-S-oxide was chosen since its enantiomers exhibited high rotation in optical rotary dispersion (ORD) and circular dichr...

journal_title：Chemistry and physics of lipids

authors： Akesson B,Michelsen P

更新日期：1981-12-01 00:00:00

abstract：:Previously unknown 4,5-epoxy-N-acetyl-sphingosine (1) was synthesized by epoxidation of N-acetyl-sphingosine with 1,1-dimethyldioxirane. A by-product generated by HPLC purification is the tetrahydrofuryl derivative of acetamide (2). Mainly allylic oxidation was observed when natural ceramides were reacted with dimethy...

journal_title：Chemistry and physics of lipids

authors： Möllenberg A,Spiteller G

更新日期：2001-02-01 00:00:00

abstract：:The 220 MHz PMR spectra of 143 non-conjugated alkenoic and alkynoic acids and esters are correlated so as to provide a method for the structural analysis of such compounds in general. The spectral data are explained in terms of long-range deshielding of the double bonds, triple bonds, acid and ester groups in the mole...

journal_title：Chemistry and physics of lipids

authors： Frost DJ,Gunstone FD

更新日期：1975-09-01 00:00:00

abstract：:Thio analogs of platelet activating factor (PAF) are of great interest because they exhibit antineoplastic properties both in vitro and in vivo. In contrast to most known anticancer agents, these lipids appear not to act through the synthesis and function of DNA and, therefore, offer a new avenue of approaching cancer...

journal_title：Chemistry and physics of lipids

authors： Mavromoustakos T,Theodoropoulou E,Yang DP,Lin SY,Koufaki M,Makriyannis A

更新日期：1996-11-01 00:00:00